e‐LEUKEMIA: The nanoconductance of redox proteins of the respiratory chain
and its p
physiopathological
y p
g
implication
p
in leukemia.
ADRESSED PATHOLOGY: Cancer
GENERAL OBJECTIVES: the project aims to investigate the redox regulation of the respiratory chain of
CSCs as a therapy against leukemia and to create a correlation model of electron transfer chain
alteration effects that would contribute to the identification of relevant parameters involved in the
inhibition of the mithocondrial respiratory chain, to be considered for the future design of new anti‐
cancer drugs, less toxic and more effective.
PARTICIPANTS:
— Pau Gorostiza. Nanomemb‐UB. University
P G
i N
b UB U i
i of Barcelona.
fB
l
— Josep Samitier. Nanomed‐IBEC. Bioengineering Institute of Catalonia.
CLINICAL GROUPS:
— Ramon Mangues. Hospital de la Santa Creu
Ramon Mangues Hospital de la Santa Creu i Sant
i Sant Pau.
Pau
EXTERNAL GROUPS:
— Miquel Àngel de la Rosa Acosta. Instituto Bioquímica Vegetal y Fotosíntesis de Sevilla. IBVF