Titan™ UHPLC Columns (1.9 μm)
Outperforms other UHPLC columns with the narrowest particle size distribution
of any sub-2 μm totally porous particles
Figure 2. Titan C18 Performance Comparison in Acetonitrile
Comparison of the Titan performance to commercially available sub-2 μm columns
Dionex® 3000 (Low D tubing)
column:
mobile phase:
temp:
flow rate:
detection:
Supelco® introduces Titan™ C18 UHPLC columns, based on 1.9 μm
totally porous, monodisperse silica particles. These particles are the
result of a newly developed, patent-pending, Ecoporous™ silica
manufacturing process.
5 cm x 3.0 mm I.D.
60% acetonitrile
35 °C
0.9 mL/min (4 mm/s)
254 nm
1.
2.
3.
4.
5.
Uracil
Diazepam
Toluene
Naphthalene
Biphenyl
Titan delivers:
• Efficiency > 250,000 N/m, comparable to leading UHPLC columns
particle size distribution translates to rugged, reliable
• Narrow
performance
• A great value, available at half the cost of other UHPLC columns
3
Titan C18, 1.9 μm
N= 14,710
N/m = 294,200
h= 1.75
σ= 1.05
Pressure*= 4,100psi
2
1
5
4
1.0
Min
Competitor A C18, 1.8 μm
Figure 1. Particle Size Distribution Comparison for Different Silicas
N= 9,260
N/m= 185,200
h= 3.18
σ= 1.02
Pressure*= 4,650psi
14
Titan (1.9 µm)
Incremental
Number
(%)
12
2.0
3
2
1
5
4
Competitor A (1.8 µm)
Competitor B (1.7 µm)
10
1.0
Min
8
2.0
Competitor B C18, 1.7 μm
N= 9,783
N/m= 195,700
h= 2.84
σ= 1.16
Pressure*= 4,900psi
6
4
3
2
1
4
5
2
0
0
0.5
1
2
Particle Size (μm)
1.5
2.5
3
3.5
4
1.0
Min
* Total System Pressure
2.0
Ordering Information
Table 1. Titan Porous Silica Characteristics
Particle
Size* μm
Pore
Diameter Å
Surface
Area m2/g
1.9
80
410
*Very narrow distribution: D (90/10) < 1.15
Pore
Pressure
Volume cc/g psi (bar)
0.76
18000 (1241)
Description
Titan C18 Columns, 1.9 μm
2 cm x 2.1 mm
3 cm x 2.1 mm
5 cm x 2.1 mm
7.5 cm x 2.1 mm
10 cm x 2.1 mm
3 cm x 3.0 mm
5 cm x 3.0 mm
Titan C18 Guard Cartridges, 1.9 μm
2.1 mm
3.0 mm
Titan Guard Cartridge Holder
(cartridge not included)
Qty.
Cat. No.
1
1
1
1
1
1
1
577120-U
577121-U
577122-U
577123-U
577124-U
577125-U
577126-U
3
3
1
577127-U
577128-U
577133-U
For more information, visit
sigma-aldrich.com/titan
Enabling Science to
Improve the Quality of Life
Order/Customer Service (800) 325-3010 • Fax (800) 325-5052
Technical Service (800) 325-5832 • sigma-aldrich.com/techservice
Development/Custom Manufacturing Inquiries
(800) 244-1173
Safety-related Information sigma-aldrich.com/safetycenter
©2013 Sigma-Aldrich Co. LLC. All rights reserved. SIGMA-ALDRICH and SUPELCO are trademarks of Sigma-Aldrich Co. LLC, registered in the US and other countries. Ecoporous, Titan and Solutions within are trademarks of Sigma
Aldrich Co. LLC. Fused-Core is a registered trademark of Advanced Materials Technology, Inc. Dionex is a registered trademark of Thermo Fisher Scientific. Supelco brand products are sold through Sigma-Aldrich, Inc. Purchaser must
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the invoice or packing slip.
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