curriculum vitae - Seribiotech Research Laboratory

CURRICULUM VITAE
Research Achievements in Brief
1.
Invited to deliver “KEY NOTE ADDRESS” in “National conference on Tree Biotechnology 2013”,
held on 23-24 Sept 2013 at Institute of Forest Genetics and Tree Breeding, Coimbatore, India.
2.
World’s first mulberry genetic linkage map has been published (Tree Genet. & Genomes 2006, 3: 1524).
3.
Analyzed 13 Morus spp. with DNA bar-coding techniques and concluded that there is no species
differentiation in the genus Morus.
4.
I am having 33 years of quality research experience in Plant Molecular Breeding, Genetics and
Breeding, published 41 research papers in reputed International and National journals.
5.
a) Worked as a Visiting Scientist at National Institute of Sericultural and Entomological Sciences,
Tsukuba, Japan on mulberry anther, pollen, protoplast culture and fusion with Science & Technology
Agency (STA), Japan fellowship.
b) Trained at International and National level on Next Generation Sequencing (NGS) technologies,
Marker Assisted Breeding (MAB) strategies, genomic selection, Bioinformatics, Biostatics, DNA
Marker technologies, DNA fingerprinting for crop improvement.
c) I am having research experience in i) Next Generation sequencing (NGS) technologies, epigenetics,
Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES), Methylomics, Joint Linkage
Association Mapping (JLAM) technologies, Ultra bar-coding technology and transposon
fingerprinting for germplasm conservation and diversity enhancement, Bioinformatics, linkage and
QTL mapping, DNA fingerprinting; cloning and characterization of functional genes, molecular
cytogenetic techniques etc.
d) ii) Open pollinated Hybridization (OPH), Controlled pollinated Hybridization (CPH), development of
tetraploids, triploids, haploids and doubled haploids (DH), protoplast culture and fusion for
obtaining somatic hybrids. Pseudo-test crossing and pseudo-backcrossing mapping technologies.
e) In vitro screening for biotic and abiotic stresses and having 5 years teaching experience in Plant
breeding, Genetics and molecular biology to M. Sc students at University of Mysore, CSR&TI,
Mysore and Kakatiya University, Warangal.
f) Trained several experts in Plant Molecular Breeding, Genetics; evaluated several papers for
publication and projects for funding and evaluated Ph. D thesises.
1. Name of the Applicant: Dr. MODALA VENKATESWARLU
2. Nationality
: INDIAN
3. Gender
: Male
4. Designation & Place : Scientist D
of Research Institute Seribiotech Research Laboratory, Central Silk Board,
where presently
Ministry of Textiles, Govt. of India, Kodathi, BANGALOREworking
560 035, India; Phone: 91-80-28440651(O)
91-80-28439406 (Home); Mobile: 91-9886233731;
Fax: 91-80-28439597; [email protected]
5. Marital status:
: Married and having one daughter
6. Research Experience : 35 years
7. Special achievements: World’s first genetic linkage map of mulberry tree (Morus
spp.) Published in Tree Genetics & Genomes 3: 15-24, 2006.
Cited by 60 International publications.
8. Scientific publications: 42 (Please see list of publications)
9. Field of Research
: Plant Molecular Breeding, Breeding, Genetics, epigenetics etc.
10. Teaching experience: Having 5 years teaching experience in Plant
breeding, Genetics and molecular biology to M. Sc
students at University of Mysore, Central Sericultural
Research &Training Institute (CSR&TI), Mysore and
Kakatiya University, Warangal.
Technical Expertise Acquired:
1. Plant Molecular Breeding:
1. Development of mapping populations including pseudo test cross and pseudo
back cross.
2. Identification of Molecular Markers associated with economic traits in
plants.
3. Construction of Genetic Linkage Maps and QTL mapping (with
MAPMAKER, QTL Cartographer). Joint Linkage Association Mapping
techniques, genomic selection, transcriptomics, epigenetics, molecular
cytogenetic techniques, Molecular characterization of plant germplasm with
DNA fingerprinting.
4. Next Generation Sequencing (NGS) technologies, Whole Genome Sequencing
(WGS), Whole Exome Sequencing (WES) and Methylomics.
5. Plant Breeding techniques.
a. Open pollinated hybridization, Controlled pollinated hybridization,
pseudo-test cross. Pseudo-back cross etc..
b. Development of tetraploids, triploids through colchicin treatment,
crossing between tetraploids and diploids.
c. Mutation breeding techniques.
d. Cytology and mutation breeding techniques in Catharanthus roseus
and mulberry (Morus spp.).
6. Plant Tissue culture techniques:
a. Induction of haploids through anther, pollen, ovary, ovule cultures
and diploidization through colchicine treatment to get homozygous
diploids (DH).
b. Protoplast isolation, culture, regeneration and fusion studies to obtain
somatic hybrids.
c. In vitro screening techniques for biotic and abiotic stresses.
Research projects pursued/pursuing/proposed
Duration of Research
As Scientist-D, Seribotech Research
Laboratory, Bangalore
June 2001 to till date
Research Projects dealing/dealt/proposed
Genetic characterization of mulberry Germplasm Resources for conservation
and valorization with high throughput genomic technologies”. Rs. 122.532
lakhs; submitted to Ministry of Environment & Forests, India for funding.
Cloning and characterization of drought-resistance genes in mulberry (Morus
spp.) and mulberry germplasm screening for drought resistance.
Isolation and characterization of Microsatellite markers in mulberry (Morus
spp.) genome. Funded by Central Silk Board.
Construction of genetic linkage maps and QTL analysis of economically
important traits in mulberry.
Genome analysis in Muga silkworm food plants: development of molecular
markers and genetic linkage maps for economically important traits.
As Senior Scientist
CSR&TI, Mysore
Dec 1986 to May 2001
Dissection of mulberry genome: Further studies on genetic variability,
characterization of genes associated with productivity.
Genome analysis in mulberry: profiling of important germplasm using
Molecular Markers and development of Mapping populations (in
collaboration with Centre for Cellular & Molecular Biology, Hyderabad and
funded by Department of Biotechnology, India
Evaluation and cataloguing of mulberry germplasm with isoenzyme gene
markers.
Induction of haploids through anther, pollen, Ovary and Ovule cultures in
mulberry. In vitro clonal multiplication.
Protoplast isolation, culture, regeneration and fusion studies to obtain
somatic hybrids in mulberry.
As visiting Scientist at Japan with STA,
Japan Fellowship
(5-12-90 to 4-12-91)
As RA, SRF & JRF (CSIR) at Botany
Dept., Kakatiya
Univ., Warangal, AP
Evolution of superior mulberry varieties through controlled pollination and
mutation breeding.
(Sponsored by Central Silk Board)
Anther, pollen, protoplast cultures and protoplast fusion to get haploids and
somatic hybrids respectively in mulberry.
Plant Molecular Genetics, Breeding and Cytogenetics
Academic degrees obtained:
Degree
Year of passing
M.Sc
Botany
1980
Ph.D
1985
Name of
Institute/Univ.
Kakatiya University,
Warangal, AP, India
Subjects studied
Kakatiya University,
Warangal, AP, India
Plant Breeding &
Genetics
Botany
(Cytogenetics)
Period of Research Abroad
Period
Dec90-Dec91
8th March 2013
Conference
attended
through
“Webinar”
from Los
Angels
28th Jan 2013 –
30th April 2013
Place &
Country
National
Institute of
Sericultural
and
Entomological
Sciences,
Tsukuba,
Japan
Plant Breeding
& Genetics
Dept., Univ.
Illinois,
Urbana
Los Angels,
USA
Purpose of
visit
Sponsored by
Research on
mulberry
Biotechnology
Science & technology Agency (STA),
Japan fellowship
Crop
improvement
in a changing
environment
Conference sponsored by Dupont
To visit
daughter and
tour USA
Daughter and Self
Period spent in India as visiting Scientist/workshops/conferences attended
Period
Jun99-aug99
Place & Country
Center for Cellular &
Molecular
Biology,Hyderabad
Jan2000Feb2000
Tata Energy Research
Institute, New Delhi
4-8 th Feb. 2002
CSR&TI, Mysore
4th – 8th Dec
2002
18th –22nd Mar.,
2003
14th Feb to 24th
Feb 2010
Central Silk Board,
Bangalore
Indian Institute of
Science, Bangalore
IARI, New Delhi, New
Delhi
Training on Statistical
methods
Data mining applications
in Bioinformatics
Marker assisted Breeding
strategies in crop plants
29th to 31st Aug
2012
ICRISAT, Hyderabad,
India
3rd International
workshop on Application
of Next Generation
Sequencing technologies
in Crop Improvement
“National Conference on
Tree Biotechnology 2013”
23 to 24
September 2013
Institute of Forest
Genetics and Tree
Breeding,
Coimbatore, India
7th April 2014
Indian Institute of
Science, Bangalore
11Th Sept 2014
Genotypic Pvt. Ltd.,
Bangalore
Purpose of visit
Research on mulberry
DNA fingerprinting
studies (AFLP, RAPD,
ISSR, CAPS etc.)
Training on DNA based
marker technologies in
plants
Training on
Bioinformatics
Sponsored by
Department of Science &
Technology, New Delhi
IGBP Symposium on
“Geosphere-Biosphere
Interactions in a Future
Earth”
Application of NGS
technologies in
Agriculture and Medicine
Department of
Biotechnology (DBT), New
Delhi
Department of
Biotechnology (DBT), New
Delhi
Central Silk Board,
Bangalore
Department of
Biotechnology, New Delhi
Indian Agricultural
Research Institute, New
Delhi, India
ICRISAT, Hyderabad,
India
Ministry of Environment &
Forestry, India
International GeosphereBiosphere Programme
(IGBP), Sweden
Genotypic Pvt. Ltd.,
Bangalore with the support
of other private firms
Others:
1.
2.
3.
4.
5.
Co-Chairman for two mulberry improvement sessions and presented a Lead paper in “National
Seminar on Scenario of Seribiotechnological Research in India, 28th – 30th Aug 2008, held at
Department of Sericulture, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, A.P.,
India.
Ph.D. thesises evaluation and recommendation for award of Ph.D.
Guided eight M. Sc students in Plant Molecular Breeding for dissertation and guiding JRFs
under various projects. Training Research staff.
Reviewing as a referee several research papers for publication and in several International
journals and evaluation of projects for funding.
Ph. D. guide under Biotechnology Dept, University of Mysore, Mysore, India.
Signature of the applicant
(Dr. Modala Venkateswarlu)
List of publications of Dr. Modala Venkateswarlu, Scientist-D, SBRL
1. M. Venkateswarlu, S. Raje Urs, B. Surendra Nath, H.E. Shashidhar, M.
Maheswaran, T.M. Veeraiah and M.G. Sabitha 2006 A first genetic
linkage map of mulberry (Morus spp.) using RAPD, ISSR and SSR
markers and pseudotestcross mapping strategy. Tree Genet & Genomes
3: 15-24.
2. Invited keynote address presentation: M. Venkateswarlu, V. Sivaprasad, G.
Ravikumar 2013 Tree Genetic Mapping: Recent Advances and Future
Perspectives. Theme: 5-Marker Assisted Selection. In: Proc. National Seminar
Tree Biotech. 2013; Emerging opportunities in forestry and tree Science,
(Eds.) M. Dasgupta, R.R. Warrier, R. Yasodha, IFGTB, Coimbatore, Tamilnadu,
India, 23-24 Sept 2013.
3. M. Venkateswarlu, G, Ravikumar, N.B. Vijayaprakash, C.G.P. Rao, C.K. Kamble
and A. Tikadar 2012 Molecular phylogeny of Morus species differentiation
based on chloroplast matK sequences. Indian J. Sericulture. 51: 16-19.
4. G. Ravikumar, K.V. Vardhana, Rajni bala, M. Venkateswarlu, G.P. Rao and Vikas
Kumar 2014 Yeast two-hybrid screen reveals novel protein interactions of the
cytoplasmic tail of lipophorin receptor (LpR4) in silkworm brain. J. Mol.
Recognition. 27: 190-196.
5. Invited Lead paper: M. Venkateswarlu and S. Raje Urs 2008 Construction of
Genetic Linkage and QTL maps of economic traits in mulberry (Morus
spp.). National Seminar on scenario of Seribiotechnological Research in India,
28th – 30th Aug 2008, Department of Sericulture, Sri Pamavati Mahila
Viswavidyalam, Tirupati – 517502, A.P, India, Souvenir, pp 15-22.
6. M. Venkateswarlu, B. Surendra Nath, B. Saratchandra and S. Raje Urs 2004
Evaluation of ISSR and RAPD markers for their utility in detecting
genetic diversity in mulberry (Morus spp.). Inter. J. Indus. Entomol.,
9: 207 – 215.
7. M. Venkateswarlu, B. Saratchandra, B. Surendra Nath and S. Raje
Urs 2004 Strategies for genome mapping and marker assisted selection in
mulberry. J. Cytol. Genet. 5: 111 – 124.
8. M. Venkateswarlu, R.K. Aggarwal & A. Sarkar 2002 An easy and simple method
of DNA extraction and purification in mulberry. J. Cytol. Genet.,
3: 163-174.
9. M. Venkateswarlu 2001 Genome analysis in mulberry (Morus spp.): DNA
profiling of germplasm using molecular markers and development of
mapping populations at the Central Sericultural Research and Training
Institute (CSR&TI), Srirampura, Mysore, India. IOPB News Letter
(Germany), 33: 13-14.
10. J. S. Kumar, A. Sarkar, B. N. Susheelamma & M. Venkateswarlu 2002
Identification of mulberry genotypes for cultivation as tree.
Indian J. Sericult., 41: 78-79.
11. M. Venkateswarlu, B.N. Susheelamma, A. Sarkar & R.K. Datta 1994 Isozyme
studies in mulberry germplasm introduced from Rajasthan. Indian J.
Sericult., 33: 98-99.
12. K. Katagiri & M. Venkateswarlu 1993 Induction of calli and organ-like structures
in isolated pollen culture of mulberry Morus australis POIRT. J. Sericult.
Sci. Jpn., 62: 1-6.
13. K. Katagiri & M. Venkateswarlu 1991 Effect of sugars and sugar alcohols on the
division of mulberry pollen in tissue culture. J. Sericult. Sci. Jpn., 60: 514516.
14. B.N. Susheelamma, M. Venkateswarlu, K. Sengupta & N. Suryanarayana 1990
Variation in chlorophyll a, b and total chlorophyll content in F1 hybrids of
mulberry (Morus spp.). Indian J. Sericult., 29: 42-45.
15. M. Venkateswarlu, B.N. Susheelamma, N. Suryanarayana, N.K. Dwivedi & K.
Sengupta 1989 Peroxidase isozyme patterns in aneuploids of mulberry.
Sericologia (France), 29: 99-104.
16. B.N. Susheelamma, M. Venkateswarlu, N.K. Dwivedi, A.K. Sikdar, N.
Suryanarayana & K. Sengupta 1989 Polyploidy and gene dosage
Effects on peroxidase activity in mulberry. Curr. Sci., 58: 580-581.
17. M. Venkateswarlu, B.N. Susheelamma, N. Suryanarayana, & K.
Sengupta 1989 Peroxidase isozyme studies in four mulberry varieties
introduced from Indonesia. Indian J. Sericult., 28: 271-273.
18. M. Venkateswarlu, N. Suryanarayana & K. Subhash 1989 Effect of gamma rays
and EMS alone and in combination on growth and alkaloid production in
periwinkle. Adv. Plant Sci., 2: 28-32.
19. M. Venkateswarlu 1989 Ultrasonics induced mutations in periwinkle. J. pure
applied Ultrasonics, 11: 4-9.
20. M. Venkateswarlu, N. Suryanarayana & K. Subhash 1989 Hydroxyl amine
induced chlorophyll mutants in periwinkle. Biological Memoirs,
15: 104-106.
21. M. Venkateswarlu, M.V. Rajam & K. Subhash 1988 Chromosome behavior in
meiotic system of Catharanthus following treatment with gamma rays,
EMS, HA alone and in combination. Cytologia (Japan), 53: 139-145.
22. M. Venkateswarlu, B.N. Susheelamma, P. Kumar & K. Subhash 1988 Studies on
induced mutation frequency in Catharanthus roseus (L.) G. Don by
gamma rays and EMS individually and in combination. Indian J. Gnet.,
48: 313-316.
23. M. Venkateswarlu, N. Suryanarayana & K. Subhash 1988 X-ray induced meiotic
behavior in Catharanthus roseus (L.) G. Don. Biol. Memoirs, 14: 173-179.
24. P. Kumar, M. Venkateswarlu & J. Nizam 1988 Effect of X-rays on the somatic
cells of Nizella sativa L. J. Cytol. Genet., 23: 151-156.
25. J. Kashinath, M. Venkateswarlu, Ch. Ramesh Babu & K. Subhash 1988 Studies on
EMS induced mutations on Coriandrum sativum L. Res. J. Plant Environ.,
4: 63-73.
26. M. Venkateswarlu & M.N. Padma 1988 Chlorophyll content in different
mulberry varieties. CSR&TI, Mysore News Letter,, 3: 6.
27. M. Venkateswarlu, P. Kumar, J. Kashinath, T. Mogili & Ch. Ramesh Babu 1984
Chlorophyll mutation frequency induced by X-rays in Vinca rosea L. J.
Plant Nature, 1: 99-100.
28. T. Mogili, M. Venkateswarlu, A. Sadanandam & P. Kumar 1984 Mytomycin C
induced somatic pairing and chromosomal aberrations in Cuminum
cyminum (L.). J. Plant Nature, 1: 83-86.
29. J. Kashinath, M. Venkateswarlu & P. Kumar 1984 Effects of X-irradiation on
meiotic behavior in Coriandrum sativum L. J. Plant Nature, 1: 9-11.
30. M. Venkateswarlu, J. Kashinath, Ch. Ramesh Babu & P. Kumar 1983 Effects of
ultrasonics on Vinca rosea Linn. J. Acoust. Soc. India, 11: 24-27.
31. M. Venkateswarlu, P. Kumar, T. Mogili, J. Kashinath & Ch. Ramesh Babu 1983
Sterile mutant induced by Hydroxylamine in Catharanthus roseus (L.)
G. Don. Indian Bot. Reporter, 2: 82.
32. Ch. Ramesh Babu, M. Venkateswarlu, J. Kashinath, T. Mogili & P. Kumar, &
1983 EMS induced chlorophyll mutations in Cassia aungustifolia Vahl.
Club J. Swamy Bot. Club, 2: 14-16.
33. J. Kashinath, M. Venkateswarlu, Ch. Ramesh Babu, T. Mogili & P. Kumar
1983 Meiotic anomalies induced by gamma rays in Coriandrum sativum.
J. Swamy Bot. Club, 2: 136-140.
34. T. Mogili, M. Venkateswarlu, J. Kashinath, Ch. Ramesh Babu & P. Kumar 1983
EMS induced sterile mutant in Catharanthus roseus (L.) G. Don.
J. Swamy Bot. Club, 2: 91-92.
35. M. Venkateswarlu, B.N. Susheelamma, Mala V. Rajan, P.K. Tewary & A. Sarkar
1995 Peroxidase isoenzyme studies in triploids of mulberry.
Indian J. Sericult., 34: 153-155.
36. P.K. Tewary, M.K. Raghunath, M. Venkateswarlu & A. Sarkar 1996 Genotypic
differences in response to in vitro shoot development of mulberry (Morus
spp.). Indian J. Sericult., 35: 104-106.
37. M. Venkateswarlu & K. Katagiri 1991 Induction of greenish status and callus in
anther culture of mulberry. Proc. Japanese Sericulture Assoc., Mito,
Japan, Nov 28-30, 1991 p.11.
38. K. Katagiri & M. Venkateswarlu 1991 Induction of callus, embryo like and organ
like divisions in pollen culture of Indian mulberry variety Berhampore.
Proc. Japanese Sericulture Assoc., Mito, Japan, Nov 28-30, 1991 p.10.
39. M. Venkateswarlu, B.N. Susheelamma, N. Suryanarayana, N.K. Dwivedi & K.
Sengupta 1988 Peroxidase isozyme studies in aneuploids of mulberry.
Proc. Inter. Congress Tropical Sericult. Practices, Bangalore, (ed. J.
Sampath), printed at M/s Jwalamukhi Job Press, Bangalore, pp. 79-83.
40. B.N. Susheelamma, M.S. Jolly, K. Sengupta, M. Venkateswarlu & N.
Suryanarayana 1988 Quantitative assessment of drought resistant mulberry
genotypes leaves cultivated under natural stress conditions by feeding larvae
of Bombyx mori L. Proc. Inter. Congress Tropical Sericult. Practices,
Bangalore, (ed. J. Sampath), printed at M/s Jwalamukhi Job Press,
Bangalore, pp. 79-83.
41. P.K. Tewary, M. Venkateswarlu, M.K. Raghunath & A. Sarkar 1997 Application
of tissue culture techniques in mulberry propagation and breeding. In: Recent
Advances in Biotechnological Applications in Plant Tissue and Cell Culture
(eds. G.A. Ravishanker & L.V. Venkataraman), pp. 28-39, Oxford & IBH
Publishing Co. Pvt. Ltd., New Delhi & Calcutta