CURRICULUM VITAE Research Achievements in Brief 1. Invited to deliver “KEY NOTE ADDRESS” in “National conference on Tree Biotechnology 2013”, held on 23-24 Sept 2013 at Institute of Forest Genetics and Tree Breeding, Coimbatore, India. 2. World’s first mulberry genetic linkage map has been published (Tree Genet. & Genomes 2006, 3: 1524). 3. Analyzed 13 Morus spp. with DNA bar-coding techniques and concluded that there is no species differentiation in the genus Morus. 4. I am having 33 years of quality research experience in Plant Molecular Breeding, Genetics and Breeding, published 41 research papers in reputed International and National journals. 5. a) Worked as a Visiting Scientist at National Institute of Sericultural and Entomological Sciences, Tsukuba, Japan on mulberry anther, pollen, protoplast culture and fusion with Science & Technology Agency (STA), Japan fellowship. b) Trained at International and National level on Next Generation Sequencing (NGS) technologies, Marker Assisted Breeding (MAB) strategies, genomic selection, Bioinformatics, Biostatics, DNA Marker technologies, DNA fingerprinting for crop improvement. c) I am having research experience in i) Next Generation sequencing (NGS) technologies, epigenetics, Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES), Methylomics, Joint Linkage Association Mapping (JLAM) technologies, Ultra bar-coding technology and transposon fingerprinting for germplasm conservation and diversity enhancement, Bioinformatics, linkage and QTL mapping, DNA fingerprinting; cloning and characterization of functional genes, molecular cytogenetic techniques etc. d) ii) Open pollinated Hybridization (OPH), Controlled pollinated Hybridization (CPH), development of tetraploids, triploids, haploids and doubled haploids (DH), protoplast culture and fusion for obtaining somatic hybrids. Pseudo-test crossing and pseudo-backcrossing mapping technologies. e) In vitro screening for biotic and abiotic stresses and having 5 years teaching experience in Plant breeding, Genetics and molecular biology to M. Sc students at University of Mysore, CSR&TI, Mysore and Kakatiya University, Warangal. f) Trained several experts in Plant Molecular Breeding, Genetics; evaluated several papers for publication and projects for funding and evaluated Ph. D thesises. 1. Name of the Applicant: Dr. MODALA VENKATESWARLU 2. Nationality : INDIAN 3. Gender : Male 4. Designation & Place : Scientist D of Research Institute Seribiotech Research Laboratory, Central Silk Board, where presently Ministry of Textiles, Govt. of India, Kodathi, BANGALOREworking 560 035, India; Phone: 91-80-28440651(O) 91-80-28439406 (Home); Mobile: 91-9886233731; Fax: 91-80-28439597; [email protected] 5. Marital status: : Married and having one daughter 6. Research Experience : 35 years 7. Special achievements: World’s first genetic linkage map of mulberry tree (Morus spp.) Published in Tree Genetics & Genomes 3: 15-24, 2006. Cited by 60 International publications. 8. Scientific publications: 42 (Please see list of publications) 9. Field of Research : Plant Molecular Breeding, Breeding, Genetics, epigenetics etc. 10. Teaching experience: Having 5 years teaching experience in Plant breeding, Genetics and molecular biology to M. Sc students at University of Mysore, Central Sericultural Research &Training Institute (CSR&TI), Mysore and Kakatiya University, Warangal. Technical Expertise Acquired: 1. Plant Molecular Breeding: 1. Development of mapping populations including pseudo test cross and pseudo back cross. 2. Identification of Molecular Markers associated with economic traits in plants. 3. Construction of Genetic Linkage Maps and QTL mapping (with MAPMAKER, QTL Cartographer). Joint Linkage Association Mapping techniques, genomic selection, transcriptomics, epigenetics, molecular cytogenetic techniques, Molecular characterization of plant germplasm with DNA fingerprinting. 4. Next Generation Sequencing (NGS) technologies, Whole Genome Sequencing (WGS), Whole Exome Sequencing (WES) and Methylomics. 5. Plant Breeding techniques. a. Open pollinated hybridization, Controlled pollinated hybridization, pseudo-test cross. Pseudo-back cross etc.. b. Development of tetraploids, triploids through colchicin treatment, crossing between tetraploids and diploids. c. Mutation breeding techniques. d. Cytology and mutation breeding techniques in Catharanthus roseus and mulberry (Morus spp.). 6. Plant Tissue culture techniques: a. Induction of haploids through anther, pollen, ovary, ovule cultures and diploidization through colchicine treatment to get homozygous diploids (DH). b. Protoplast isolation, culture, regeneration and fusion studies to obtain somatic hybrids. c. In vitro screening techniques for biotic and abiotic stresses. Research projects pursued/pursuing/proposed Duration of Research As Scientist-D, Seribotech Research Laboratory, Bangalore June 2001 to till date Research Projects dealing/dealt/proposed Genetic characterization of mulberry Germplasm Resources for conservation and valorization with high throughput genomic technologies”. Rs. 122.532 lakhs; submitted to Ministry of Environment & Forests, India for funding. Cloning and characterization of drought-resistance genes in mulberry (Morus spp.) and mulberry germplasm screening for drought resistance. Isolation and characterization of Microsatellite markers in mulberry (Morus spp.) genome. Funded by Central Silk Board. Construction of genetic linkage maps and QTL analysis of economically important traits in mulberry. Genome analysis in Muga silkworm food plants: development of molecular markers and genetic linkage maps for economically important traits. As Senior Scientist CSR&TI, Mysore Dec 1986 to May 2001 Dissection of mulberry genome: Further studies on genetic variability, characterization of genes associated with productivity. Genome analysis in mulberry: profiling of important germplasm using Molecular Markers and development of Mapping populations (in collaboration with Centre for Cellular & Molecular Biology, Hyderabad and funded by Department of Biotechnology, India Evaluation and cataloguing of mulberry germplasm with isoenzyme gene markers. Induction of haploids through anther, pollen, Ovary and Ovule cultures in mulberry. In vitro clonal multiplication. Protoplast isolation, culture, regeneration and fusion studies to obtain somatic hybrids in mulberry. As visiting Scientist at Japan with STA, Japan Fellowship (5-12-90 to 4-12-91) As RA, SRF & JRF (CSIR) at Botany Dept., Kakatiya Univ., Warangal, AP Evolution of superior mulberry varieties through controlled pollination and mutation breeding. (Sponsored by Central Silk Board) Anther, pollen, protoplast cultures and protoplast fusion to get haploids and somatic hybrids respectively in mulberry. Plant Molecular Genetics, Breeding and Cytogenetics Academic degrees obtained: Degree Year of passing M.Sc Botany 1980 Ph.D 1985 Name of Institute/Univ. Kakatiya University, Warangal, AP, India Subjects studied Kakatiya University, Warangal, AP, India Plant Breeding & Genetics Botany (Cytogenetics) Period of Research Abroad Period Dec90-Dec91 8th March 2013 Conference attended through “Webinar” from Los Angels 28th Jan 2013 – 30th April 2013 Place & Country National Institute of Sericultural and Entomological Sciences, Tsukuba, Japan Plant Breeding & Genetics Dept., Univ. Illinois, Urbana Los Angels, USA Purpose of visit Sponsored by Research on mulberry Biotechnology Science & technology Agency (STA), Japan fellowship Crop improvement in a changing environment Conference sponsored by Dupont To visit daughter and tour USA Daughter and Self Period spent in India as visiting Scientist/workshops/conferences attended Period Jun99-aug99 Place & Country Center for Cellular & Molecular Biology,Hyderabad Jan2000Feb2000 Tata Energy Research Institute, New Delhi 4-8 th Feb. 2002 CSR&TI, Mysore 4th – 8th Dec 2002 18th –22nd Mar., 2003 14th Feb to 24th Feb 2010 Central Silk Board, Bangalore Indian Institute of Science, Bangalore IARI, New Delhi, New Delhi Training on Statistical methods Data mining applications in Bioinformatics Marker assisted Breeding strategies in crop plants 29th to 31st Aug 2012 ICRISAT, Hyderabad, India 3rd International workshop on Application of Next Generation Sequencing technologies in Crop Improvement “National Conference on Tree Biotechnology 2013” 23 to 24 September 2013 Institute of Forest Genetics and Tree Breeding, Coimbatore, India 7th April 2014 Indian Institute of Science, Bangalore 11Th Sept 2014 Genotypic Pvt. Ltd., Bangalore Purpose of visit Research on mulberry DNA fingerprinting studies (AFLP, RAPD, ISSR, CAPS etc.) Training on DNA based marker technologies in plants Training on Bioinformatics Sponsored by Department of Science & Technology, New Delhi IGBP Symposium on “Geosphere-Biosphere Interactions in a Future Earth” Application of NGS technologies in Agriculture and Medicine Department of Biotechnology (DBT), New Delhi Department of Biotechnology (DBT), New Delhi Central Silk Board, Bangalore Department of Biotechnology, New Delhi Indian Agricultural Research Institute, New Delhi, India ICRISAT, Hyderabad, India Ministry of Environment & Forestry, India International GeosphereBiosphere Programme (IGBP), Sweden Genotypic Pvt. Ltd., Bangalore with the support of other private firms Others: 1. 2. 3. 4. 5. Co-Chairman for two mulberry improvement sessions and presented a Lead paper in “National Seminar on Scenario of Seribiotechnological Research in India, 28th – 30th Aug 2008, held at Department of Sericulture, Sri Padmavati Mahila Visvavidyalayam, Tirupati-517502, A.P., India. Ph.D. thesises evaluation and recommendation for award of Ph.D. Guided eight M. Sc students in Plant Molecular Breeding for dissertation and guiding JRFs under various projects. Training Research staff. Reviewing as a referee several research papers for publication and in several International journals and evaluation of projects for funding. Ph. D. guide under Biotechnology Dept, University of Mysore, Mysore, India. Signature of the applicant (Dr. Modala Venkateswarlu) List of publications of Dr. Modala Venkateswarlu, Scientist-D, SBRL 1. M. Venkateswarlu, S. Raje Urs, B. Surendra Nath, H.E. Shashidhar, M. Maheswaran, T.M. Veeraiah and M.G. Sabitha 2006 A first genetic linkage map of mulberry (Morus spp.) using RAPD, ISSR and SSR markers and pseudotestcross mapping strategy. Tree Genet & Genomes 3: 15-24. 2. Invited keynote address presentation: M. Venkateswarlu, V. Sivaprasad, G. Ravikumar 2013 Tree Genetic Mapping: Recent Advances and Future Perspectives. Theme: 5-Marker Assisted Selection. In: Proc. National Seminar Tree Biotech. 2013; Emerging opportunities in forestry and tree Science, (Eds.) M. Dasgupta, R.R. Warrier, R. Yasodha, IFGTB, Coimbatore, Tamilnadu, India, 23-24 Sept 2013. 3. M. Venkateswarlu, G, Ravikumar, N.B. Vijayaprakash, C.G.P. Rao, C.K. Kamble and A. Tikadar 2012 Molecular phylogeny of Morus species differentiation based on chloroplast matK sequences. Indian J. Sericulture. 51: 16-19. 4. G. Ravikumar, K.V. Vardhana, Rajni bala, M. Venkateswarlu, G.P. Rao and Vikas Kumar 2014 Yeast two-hybrid screen reveals novel protein interactions of the cytoplasmic tail of lipophorin receptor (LpR4) in silkworm brain. J. Mol. Recognition. 27: 190-196. 5. Invited Lead paper: M. Venkateswarlu and S. Raje Urs 2008 Construction of Genetic Linkage and QTL maps of economic traits in mulberry (Morus spp.). National Seminar on scenario of Seribiotechnological Research in India, 28th – 30th Aug 2008, Department of Sericulture, Sri Pamavati Mahila Viswavidyalam, Tirupati – 517502, A.P, India, Souvenir, pp 15-22. 6. M. Venkateswarlu, B. Surendra Nath, B. Saratchandra and S. Raje Urs 2004 Evaluation of ISSR and RAPD markers for their utility in detecting genetic diversity in mulberry (Morus spp.). Inter. J. Indus. Entomol., 9: 207 – 215. 7. M. Venkateswarlu, B. Saratchandra, B. Surendra Nath and S. Raje Urs 2004 Strategies for genome mapping and marker assisted selection in mulberry. J. Cytol. Genet. 5: 111 – 124. 8. M. Venkateswarlu, R.K. Aggarwal & A. Sarkar 2002 An easy and simple method of DNA extraction and purification in mulberry. J. Cytol. Genet., 3: 163-174. 9. M. Venkateswarlu 2001 Genome analysis in mulberry (Morus spp.): DNA profiling of germplasm using molecular markers and development of mapping populations at the Central Sericultural Research and Training Institute (CSR&TI), Srirampura, Mysore, India. IOPB News Letter (Germany), 33: 13-14. 10. J. S. Kumar, A. Sarkar, B. N. Susheelamma & M. Venkateswarlu 2002 Identification of mulberry genotypes for cultivation as tree. Indian J. Sericult., 41: 78-79. 11. M. Venkateswarlu, B.N. Susheelamma, A. Sarkar & R.K. Datta 1994 Isozyme studies in mulberry germplasm introduced from Rajasthan. Indian J. Sericult., 33: 98-99. 12. K. Katagiri & M. Venkateswarlu 1993 Induction of calli and organ-like structures in isolated pollen culture of mulberry Morus australis POIRT. J. Sericult. Sci. Jpn., 62: 1-6. 13. K. Katagiri & M. Venkateswarlu 1991 Effect of sugars and sugar alcohols on the division of mulberry pollen in tissue culture. J. Sericult. Sci. Jpn., 60: 514516. 14. B.N. Susheelamma, M. Venkateswarlu, K. Sengupta & N. Suryanarayana 1990 Variation in chlorophyll a, b and total chlorophyll content in F1 hybrids of mulberry (Morus spp.). Indian J. Sericult., 29: 42-45. 15. M. Venkateswarlu, B.N. Susheelamma, N. Suryanarayana, N.K. Dwivedi & K. Sengupta 1989 Peroxidase isozyme patterns in aneuploids of mulberry. Sericologia (France), 29: 99-104. 16. B.N. Susheelamma, M. Venkateswarlu, N.K. Dwivedi, A.K. Sikdar, N. Suryanarayana & K. Sengupta 1989 Polyploidy and gene dosage Effects on peroxidase activity in mulberry. Curr. Sci., 58: 580-581. 17. M. Venkateswarlu, B.N. Susheelamma, N. Suryanarayana, & K. Sengupta 1989 Peroxidase isozyme studies in four mulberry varieties introduced from Indonesia. Indian J. Sericult., 28: 271-273. 18. M. Venkateswarlu, N. Suryanarayana & K. Subhash 1989 Effect of gamma rays and EMS alone and in combination on growth and alkaloid production in periwinkle. Adv. Plant Sci., 2: 28-32. 19. M. Venkateswarlu 1989 Ultrasonics induced mutations in periwinkle. J. pure applied Ultrasonics, 11: 4-9. 20. M. Venkateswarlu, N. Suryanarayana & K. Subhash 1989 Hydroxyl amine induced chlorophyll mutants in periwinkle. Biological Memoirs, 15: 104-106. 21. M. Venkateswarlu, M.V. Rajam & K. Subhash 1988 Chromosome behavior in meiotic system of Catharanthus following treatment with gamma rays, EMS, HA alone and in combination. Cytologia (Japan), 53: 139-145. 22. M. Venkateswarlu, B.N. Susheelamma, P. Kumar & K. Subhash 1988 Studies on induced mutation frequency in Catharanthus roseus (L.) G. Don by gamma rays and EMS individually and in combination. Indian J. Gnet., 48: 313-316. 23. M. Venkateswarlu, N. Suryanarayana & K. Subhash 1988 X-ray induced meiotic behavior in Catharanthus roseus (L.) G. Don. Biol. Memoirs, 14: 173-179. 24. P. Kumar, M. Venkateswarlu & J. Nizam 1988 Effect of X-rays on the somatic cells of Nizella sativa L. J. Cytol. Genet., 23: 151-156. 25. J. Kashinath, M. Venkateswarlu, Ch. Ramesh Babu & K. Subhash 1988 Studies on EMS induced mutations on Coriandrum sativum L. Res. J. Plant Environ., 4: 63-73. 26. M. Venkateswarlu & M.N. Padma 1988 Chlorophyll content in different mulberry varieties. CSR&TI, Mysore News Letter,, 3: 6. 27. M. Venkateswarlu, P. Kumar, J. Kashinath, T. Mogili & Ch. Ramesh Babu 1984 Chlorophyll mutation frequency induced by X-rays in Vinca rosea L. J. Plant Nature, 1: 99-100. 28. T. Mogili, M. Venkateswarlu, A. Sadanandam & P. Kumar 1984 Mytomycin C induced somatic pairing and chromosomal aberrations in Cuminum cyminum (L.). J. Plant Nature, 1: 83-86. 29. J. Kashinath, M. Venkateswarlu & P. Kumar 1984 Effects of X-irradiation on meiotic behavior in Coriandrum sativum L. J. Plant Nature, 1: 9-11. 30. M. Venkateswarlu, J. Kashinath, Ch. Ramesh Babu & P. Kumar 1983 Effects of ultrasonics on Vinca rosea Linn. J. Acoust. Soc. India, 11: 24-27. 31. M. Venkateswarlu, P. Kumar, T. Mogili, J. Kashinath & Ch. Ramesh Babu 1983 Sterile mutant induced by Hydroxylamine in Catharanthus roseus (L.) G. Don. Indian Bot. Reporter, 2: 82. 32. Ch. Ramesh Babu, M. Venkateswarlu, J. Kashinath, T. Mogili & P. Kumar, & 1983 EMS induced chlorophyll mutations in Cassia aungustifolia Vahl. Club J. Swamy Bot. Club, 2: 14-16. 33. J. Kashinath, M. Venkateswarlu, Ch. Ramesh Babu, T. Mogili & P. Kumar 1983 Meiotic anomalies induced by gamma rays in Coriandrum sativum. J. Swamy Bot. Club, 2: 136-140. 34. T. Mogili, M. Venkateswarlu, J. Kashinath, Ch. Ramesh Babu & P. Kumar 1983 EMS induced sterile mutant in Catharanthus roseus (L.) G. Don. J. Swamy Bot. Club, 2: 91-92. 35. M. Venkateswarlu, B.N. Susheelamma, Mala V. Rajan, P.K. Tewary & A. Sarkar 1995 Peroxidase isoenzyme studies in triploids of mulberry. Indian J. Sericult., 34: 153-155. 36. P.K. Tewary, M.K. Raghunath, M. Venkateswarlu & A. Sarkar 1996 Genotypic differences in response to in vitro shoot development of mulberry (Morus spp.). Indian J. Sericult., 35: 104-106. 37. M. Venkateswarlu & K. Katagiri 1991 Induction of greenish status and callus in anther culture of mulberry. Proc. Japanese Sericulture Assoc., Mito, Japan, Nov 28-30, 1991 p.11. 38. K. Katagiri & M. Venkateswarlu 1991 Induction of callus, embryo like and organ like divisions in pollen culture of Indian mulberry variety Berhampore. Proc. Japanese Sericulture Assoc., Mito, Japan, Nov 28-30, 1991 p.10. 39. M. Venkateswarlu, B.N. Susheelamma, N. Suryanarayana, N.K. Dwivedi & K. Sengupta 1988 Peroxidase isozyme studies in aneuploids of mulberry. Proc. Inter. Congress Tropical Sericult. Practices, Bangalore, (ed. J. Sampath), printed at M/s Jwalamukhi Job Press, Bangalore, pp. 79-83. 40. B.N. Susheelamma, M.S. Jolly, K. Sengupta, M. Venkateswarlu & N. Suryanarayana 1988 Quantitative assessment of drought resistant mulberry genotypes leaves cultivated under natural stress conditions by feeding larvae of Bombyx mori L. Proc. Inter. Congress Tropical Sericult. Practices, Bangalore, (ed. J. Sampath), printed at M/s Jwalamukhi Job Press, Bangalore, pp. 79-83. 41. P.K. Tewary, M. Venkateswarlu, M.K. Raghunath & A. Sarkar 1997 Application of tissue culture techniques in mulberry propagation and breeding. In: Recent Advances in Biotechnological Applications in Plant Tissue and Cell Culture (eds. G.A. Ravishanker & L.V. Venkataraman), pp. 28-39, Oxford & IBH Publishing Co. Pvt. Ltd., New Delhi & Calcutta
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