The DMDG In-Vitro Technology Training Course Day 1 12.00 - 14.00 14.00 - 14.15 14.15 - 15.00 15:00 - 15.30 15:30 - 16.00 16.00 - 16.30 16.30 - 17.30 18.30 – 20:00 20:00 – 23:00 Delegate Arrival and Registration Course Introduction Drug Metabolism and Phase I Phase II Enzymes Coffee Introduction to Transporters Tutorial 1 (Routes of ADME) Dinner Quiz Day 2 09.00 - 09.45 09:45 - 10.15 10.15 - 10.45 10.45 - 11.30 11.30 - 13.00 13.00 - 14.00 14.00 - 14.45 14.45- 15.15 15.15 - 15.45 15:45 – 17:30 Hepatocytes Sub cellular fractions Coffee Enzyme Kinetics & Clearance Tutorial 2 (Enzyme Kinetics) Lunch Molecular Methods Transporter Phenotyping Coffee Tutorial 3 (Clearance & Transporters) 19.00 Dinner + Free evening Day 3 09.00 - 09.45 09:45 - 10.30 Inhibition of ADME Induction of ADME 10:30 - 11.00 11.00 - 12.30 12:30 - 13.30 13.30 - 14.00 14.00 - 14.45 15.00 - 15.30 15.30 - 15.45 15.45 – 17.45 17.45 – 18.00 20.00 Coffee Tutorial 4 (ADME Inhibition & Induction) Lunch In Vitro – In Vivo extrapolation Applications of In Vitro Coffee Tutorial 5 intro Tutorial 5 Tutorial 5 – Discussion/presentation Course Dinner Day 4 09.00 Delegates Depart *In the event of oversubscription, places will be allocated according to DMDG rules.
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