Schematic overview of neural circuits thought to be relevant in mesocorticolimbic neurotransmission and psychotic disorder, illustration of reported environmental impact on these regions and circuits in human studies, and the effect of repeated environmental exposures on the regulation of bottomup sensory input and top-down cognitive control by the nucleus accumbens. JV Os et al. Nature 468, 203-212 (2010) doi:10.1038/nature09563
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