Category 1 FIRMNESS + ELASTICITY Your Score 63% 57% GLOBAL AVERAGE MEDIUM RISK You have a partial imbalance: More collagen is breaking down and less is being produced. 57% 12% RACE AVERAGE GENOTYPE Average Score based on your ancestry Percentage of people with the same outcome as you About this category Your Gene Profile Keeping the skin firm, plump and wrinkle-free, collagen makes up 75% of the skins dry weight. Your genetic predispositions play a big role in determining both the speed of collagen production and breakdown. Collagen Breakdown Visible & Internal Signs Prolonged Redness Poor Wound Healing Accelerated Aging Skin Laxity & Sagging Hollowing Under Eyes Your Scientifically Selected Program Collagen Imbalance Wound Healing Issues Increased Collagen Breakdown Slowdown in Tissue Remodelling Why do we experience Sagging Skin? When you are younger, your body makes more collagen than it loses, but after about the age of 40, collagen loss can accelerate, leading to a decline in the health and appearance of your skin. This process is precipitated by a protein called MMP1 or Collagenase. Collagen BALANCE In youthful skin, production and degradation of Collagen is in balance. Collagen Protection Collagen IMBALANCE Genetic abnormalities can can cause increased collagen breakdown. The SkinDNATM Genetic ® Test can help identify if the rise and fall of collagen is in balance, or if the breakdown of collagen predominates, which can result in the appearance of premature wrinkling, aging and sagging of the skin. Topical Ingredients Coenzyme Q10 Protects the dermis from degradation Resveratrol Stimulates collagen synthesis Epidermal Growth Factors Stimulates skin cell reproduction Retinol 0.5% Stimulates skin cell reproduction L-ascorbic Acid 15%+ Promotes collagen production Vitamin E Along with L-ascorbic Acid helps to neutralize free radicals Palmitoyl Oligopeptide Collagen communicator to boost production Supplemental Ingredients Alpha Lipoic Acid Raises collagen protective mechanisims Vitamin C + E Can help decrease MMP activity N-Acetyl Cysteine Amino acid shown to reduce MMP damage Whey Protein Maximizes collagen protective mechanisims Soy Isoflavones Can help decrease MMP activity Professional Treatments Collagen Induction Therapy Increases collagen production Glycolic Acid Stimulates collagen growth Radio Frequency / IR Increases collagen production LED - Red Light / Near IR Temporarily reduces MMP activities Category 2 WRINKLING (A.G.E.) YOUR SCORE Turnover 25% 77% GLOBAL AVERAGE HIGHER RISK Your body has reduced functioning ability to efficiently metabolise glucose: If glucose is not completely metabolized the excess stored can cause Glycation. If you have a high sugar diet can increase your lifetime risk to Glycation. About this category Glycation is heavily implicated in accelerated skin aging and has been described as carmelization of the skin from the inside out. Glycation occurs when excess bodily glucose molecules link to the skin’s Collagen and Elastin fibers. This cross-linking can form chemical bridges between these proteins. Visible & Internal Signs Heavy Wrinkles & Folds Accelerated Aging Cracking and Thinning Skin Uneven Skin Texture Pillowing of the Skin Decreased Skin Elasticity Stiffened Collagen Fibers Glucose/Collagen Cross Linking Weak Dermal Epidermal Junction 23% 62% Average Score based on your ancestry Percentage of people with the same outcome as you RACE AVERAGE GENOTYPE Your Gene Profile Glycation Interruption Your Scientifically Selected Program Topical Ingredients Blueberry Extract Stabilizes collagen matrix Kombucha Decelerates glycation bonding Epidermal Growth Factors Stimulates skin cell reproduction Vitamin B6 - Pyridoxine Shown to prevent the formation of glycation end-products Hyaluronic Acid Retains water within the dermis to reduce appearance of glycated skin Supplemental Ingredients Alpha Lipoic Acid Reduces the formation of glycation end products Glycation, crepe-like skin YOUNG SKIN Healthy Collagen Fibers AS WE AGE Stiffened Cross linked Collagen fibers due to Glycation How your body processes sugar is determined in part by your genes. Variations in the these genes can alter the functioning of normal glucose levels and energy metabolism. Glycated collagen fibers can become rigid, less elastic and have reduced regenerative ability which can lead to damage such as laxity, cracking and thinning skin. The SkinDNA Genetic Test can help to identify genetic variations that can alter the functioning of normal glucose levels and energy metabolism. While glucose is a vital cellular fuel, if not fully metabolized by the body Glycation can occur. Blueberry Extract Reduces the glycation cycle Low Dose Aspirin Reduces the glycation cycle Quercetin Shown to reduce glycation end product formation Carnosine Reduces the formation of glycation end products Professional Treatments Collagen Induction Therapy Increases collagen production and cellular turnover Low Sugar Diet Consult a professional before commencing dietary changes Your Summary YOU+ HOW YOUR SKIN MAY AGE FIRMNESS + ELASTICITY 0 1 100 38 WRINKLING (A.G.E) 0 100 SUN DAMAGE + PIGMENTATION 0 1 3 100 63 1 3 5 FREE RADICAL DAMAGE 0 83 100 1 SENSITIVITY + INFLAMMATION 0 69 100 1 4 58% YOUR SCORE 1 Firmness / Laxity 2 Wrinkling / Glycation 3 Pigmentation 4 Antioxidant Protection 5 Sensitivity / Irritation 3 You have an imbalance - more collagen is breaking down and less is being produced. Your bodies ability to efficiently breakdown glucose levels is normal. However if you lead an unhealthy routine consisting of a high sugar diet can ultimately increase your lifestyle risk to Glycation. Your body is partially efficient in producing melanin as well as other various processors that aim to protect your skin from the sun. You may also have a higher chance of irregular pigmentation and burning. Your body’s ability to produce essential antioxidants is normal. However by living an unhealthy lifestyle that includes smoking, high stress and bad diet can ultimately increase free radical production, which will increase your risk of cellular damage You have a partial oversupply of inflammatory proteins. As a result, the extra inflammation produced may cause rash, redness or irritations. You may also have a partial risk of chemical sensitivity found in perfumed products and city pollution. Your Summary YOUR SUMMARY YOU+ FIRMNESS + ELASTICITY Collagen Breakdown 11q21-q22 2G2G Deficient Collagen Protection 11q21-q22 AA Normal You have a partial imbalance: The enzyme responsible for collagen breakdown (MMP) is heightened. Your genes have partially reduced functioning ability to produce Glutathione Antioxidant and may not be providing optimum support to protect your collagen levels from the effects of over-active collagen breakdown activity. YOUR SCORE More collagen is breaking down and less is being produced. 63% MEDIUM RISK 57% GLOBAL AVERAGE WRINKLING (A.G.E.) Glycation Interruption 11q21-q22 AA Deficient Your body has reduced functioning ability to efficiently metabolise glucose: If glucose is not completely metabolized the You have reduced functioning ability to efficiently breakdown glucose. If glucose is not completely metabolised the excess stored can cause Glycation. Excess glucose molecules stick to Collagen and Elastin resulting in cross-linked fibers binding them YOUR SCORE excess stored can cause Glycation. If you have a high sugar diet can increase your lifetime risk to Glycation. 25% HIGHER RISK 77% GLOBAL AVERAGE SUN DAMAGE + PIGMENTATION Melanin Production M1 11q21-q22 AA Sub-Normal Melanin Production M2 11q21-q22 AA Sub-Normal Ultraviolet Genetic Repair 11q21-q22 AA Normal DNA Photo Repair M1 11q21-q22 AA Deficient DNA Photo Repair M2 11q21-q22 AC Sub-Normal UV Radical Repair 11q21-q22 CC Normal Your bodies ability to protect your skin from the sun is optimal: However by sunbathing everyday or not taking care while outdoors can ultimately increase your lifestyle risk of sun damage, UV damage and pigmentation issues. Your results indicate that your body is moderately able to produce melanin (pigment). It is likely that your skin provides the volume of melanin needed to protect you for short intervals of sunlight exposure. It is likely that your body has the ability to tan, you may find that longer exposure causes sensitivity, freckling and other various pigmentation spots with minimal sun burning symptoms. Normal ability to repair DNA damage caused from UV exposure. Heightened sensitivity and reduced ability to break down radicals produced from UV exposed skin cells. Normal DNA repairing ability. After UV exposure this gene is crucial for maintaining the overall health and integrity of skin by repairing DNA damage caused by UV exposure. YOUR SCORE 78% LOW RISK 62% GLOBAL AVERAGE Your Summary YOUR SUMMARY YOU+ FREE RADCIAL DAMAGE Superoxide Radical Defence 2G2G 11q21-q22 Deficient Glutathione Production AA Normal Pollution Defence 11q21-q22 AA Deficient Reduced ability to produce essential antioxidants: Your genes have normal functioning ability to produce Glutathione Antioxidant. As you have Reduced ability to produce Superoxide Dismutase the benefits of normal functioning Glutathione antioxidant will aid in helping to efficiently breakdown free radicals and prevent unnecessary damage to skin cells. You have a reduced ability to efficiently breakdown Quinones found in Environmental pollutants, this can cause skin to become sensitive to Environmental pollutants. YOUR SCORE You may also have an increased risk of sensitivity to Environmental Pollutants such as city smog. Doing what you can to reduce free radical production is essential to a longterm healthy dermis. 56% HIGHER RISK 76% GLOBAL AVERAGE SENSITIVITY + INFLAMMATION Acute Inflammation 11q21-q22 AA Sub-Normal The gene responsible for the regulation of inflammation is over-reactive and can result in the body’s ability to over- respond to a threat causing a sometimes heightened inflammatory response unnecessary to skin cells. Itching and redness, rashes and sensitivity. It is likely that you could also suffer from allergies such as hay fever and various other allergies. Internal Toxins Protection 11q21-q22 AA Sub-Normal Your genes have reduced functioning ability to breakdown xenobiotic compounds such as cigarette smoke, exhaust fumes, air pollution and alcohol. Variations in this gene can create internal inflammatory responses. These responses can manifest into redness, rashes and acne. Dermal Sensitivity M1 11q21-q22 AA Normal Dermal Sensitivity M2 11q21-q22 AA Deficient Genetically your body is able to breakdown toxic chemical compounds found in everyday pollutions. At the same time you may still partially be sensitive to certain perfumed products, active skincare ingredients and general city pollution. Genetically, your body is producing normal levels of inflammatory proteins: You have a reduced risk of chemical sensitivity and skin inflammation. You may still at times experience skin irritations when using a highly active products. YOUR SCORE 82% LOW RISK 80% GLOBAL AVERAGE
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