FT-11708E
DeOxyCholic acid, Sodium Salt
Product Information
Catalog #:
Name:
UP1170E, 50g
DeOxyCholic acid, Sodium Salt
Sodium DeOxyCholic acid, Deoxycholate Sodium Salt,
3 ,12 a-Dihydroxy-5β-cholan-24-oic acid, mono sodium salt
C24H39O4Na
MW : 414.57
CAS [302-95-4]
Storage:
Room temperature (Z)
(–20°C for long term)
Physical properties:
Melting Point:
117°C
Aggregation Number:
5 (average)
Micelle MW:
2000 (average)
Critical Micelle Concentration: CMC (H2O) 2-6 mM or ~0.083 - 0.249% (w/v)
Solubility in water:
>5%
Extinction Coefficient:
A280nm: <0.04 (1% detergent Solution)
A340nm: <0.02
A260nm: <0.06
Specifications:
Arsenic
Heavy Metals
Loss on Drying
Purity (Dry Basis)
Sodium Cholate
Solubility (10%, Water)
<=0.001%
<=0.005%
<=5.0%
>99.0%
<=2.0%
PASS
Technical and Scientific Information
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Sodium Deoxycholate solutions may become viscous or gel-like when refrigerated. Allow the detergent to
warm to room temperature to decrease viscosity.
At concentrations above 2 mM, cholate will form micelles having MW ~2000. The small size of these micelle
allows them to be easily removed by dialysis or gel filtration if needed. Note: removal of a detergent from a
protein solution my result in protein precipitation and/or aggregation.
Because the effectiveness of a detergent in any application is dependent on the detergents concentration, it is
recommended to refer to the literature, or calibrate if required the detergent concentrations in your application.
Applications: Sodium Deoxycholate is water soluble ionic detergent/bile salt commonly used in applications
ranging from cell lysis (RIPA Buffer), liposome preparation, isolation of membrane proteins and lipids,
preventing nonspecific binding in affinity chromatography and a cell culture media supplement. Sodium
Deoxycholate is also used for stripping endotoxin (Lipopolysaccharide or LPS).
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FT-11708E
Legals
Xn, R22: Harmful if swallowed
Xi, R36/37: Irritating to eyes and respiratory system
S2: keep out of the reach of children
Physical/chemical hazards: not applicable
Related products
Other detergents: see pages B2+ of our BioSciences catalog.
Desalting tools
Ordering information
Catalog size quantities and prices may be found at http://www.interchim.com
Please inquire for higher quantities (availability, shipment conditions).
For any information, please ask : Uptima / Interchim; Hotline : +33(0)4 70 03 73 06
Disclaimer : Materials from Uptima are sold for research use only, and are not intended for food, drug, household, or cosmetic use. Uptima is not
liable for any damage resulting from handling or contact with this product.
Rev.I02E
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[email protected]
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