Table S2. KEGG Pathways examined.
KEGG pathway
hsa00010
hsa00020
hsa00030
hsa00031
hsa00040
hsa00051
hsa00052
hsa00053
hsa00061
hsa00062
hsa00071
hsa00072
hsa00100
hsa00120
hsa00130
hsa00140
hsa00150
hsa00190
hsa00220
hsa00230
hsa00232
hsa00240
hsa00251
hsa00252
hsa00260
hsa00271
hsa00272
hsa00280
hsa00281
hsa00290
hsa00300
hsa00310
hsa00330
hsa00340
hsa00350
hsa00360
hsa00361
hsa00363
hsa00364
hsa00380
hsa00400
hsa00401
hsa00410
Name of pathway
Glycolysis / Gluconeogenesis
Citrate cycle (TCA cycle)
Pentose phosphate pathway
Inositol Metabolism
Pentose and glucuronate interconversions
Fructose and mannose metabolism
Galactose metabolism
Ascorbate and aldarate metabolism
Fatty acid biosynthesis
Fatty acid elongation in mitochondria
Fatty acid metabolism
Synthesis and degradation of ketone bodies
Steroid biosynthesis
Primary bile acid biosynthesis
Ubiquinone and other terpenoid-quinone biosynthesis
C21-Steroid hormone metabolism
Androgen and estrogen metabolism
Oxidative phosphorylation
Urea cycle and metabolism of amino groups
Purine metabolism
Caffeine metabolism
Pyrimidine metabolism
Glutamate metabolism
Alanine and aspartate metabolism
Glycine, serine and threonine metabolism
Methionine metabolism
Cysteine metabolism
Valine, leucine and isoleucine degradation
Geraniol degradation
Valine, leucine and isoleucine biosynthesis
Lysine biosynthesis
Lysine degradation
Arginine and proline metabolism
Histidine metabolism
Tyrosine metabolism
Phenylalanine metabolism
gamma-Hexachlorocyclohexane degradation
Bisphenol A degradation
Fluorobenzoate degradation
Tryptophan metabolism
Phenylalanine, tyrosine and tryptophan biosynthesis
Novobiocin biosynthesis
beta-Alanine metabolism
hsa00430
hsa00440
hsa00450
hsa00460
hsa00471
hsa00472
hsa00480
hsa00500
hsa00510
hsa00511
hsa00512
hsa00520
hsa00521
hsa00530
hsa00531
hsa00532
hsa00533
hsa00534
hsa00550
hsa00561
hsa00562
hsa00563
hsa00564
hsa00565
hsa00590
hsa00591
hsa00592
hsa00600
hsa00601
hsa00602
hsa00603
hsa00604
hsa00620
hsa00624
hsa00625
hsa00627
hsa00630
hsa00632
hsa00640
hsa00641
hsa00643
hsa00650
hsa00670
hsa00680
hsa00710
hsa00720
Taurine and hypotaurine metabolism
Aminophosphonate metabolism
Selenoamino acid metabolism
Cyanoamino acid metabolism
D-Glutamine and D-glutamate metabolism
D-Arginine and D-ornithine metabolism
Glutathione metabolism
Starch and sucrose metabolism
N-Glycan biosynthesis
Other glycan degradation
O-Glycan biosynthesis
Amino sugar and nucleotide sugar metabolism
Streptomycin biosynthesis
Aminosugars metabolism
Glycosaminoglycan degradation
Chondroitin sulfate biosynthesis
Keratan sulfate biosynthesis
Heparan sulfate biosynthesis
Peptioglycan biosynthesis
Glycerolipid metabolism
Inositol phosphate metabolism
Glycosylphosphatidylinositol(GPI)-anchor biosynthesis
Glycerophospholipid metabolism
Ether lipid metabolism
Arachidonic acid metabolism
Linoleic acid metabolism
alpha-Linolenic acid metabolism
Sphingolipid metabolism
Glycosphingolipid biosynthesis - lacto and neolacto series
Glycosphingolipid biosynthesis - neo-lacto series
Glycosphingolipid biosynthesis - globo series
Glycosphingolipid biosynthesis - ganglio series
Pyruvate metabolism
1- and 2-Methylnaphthalene degradation
Tetrachloroethene degradation
1,4-Dichlorobenzene degradation
Glyoxylate and dicarboxylate metabolism
Benzoate degradation via CoA ligation
Propanoate metabolism
3-Chloroacrylic acid degradation
Styrene degradation
Butanoate metabolism
One carbon pool by folate
Methane metabolism
Carbon fixation in photosynthetic organisms
Reductive carboxylate cycle (CO2 fixation)
hsa00730
hsa00740
hsa00750
hsa00760
hsa00770
hsa00780
hsa00785
hsa00790
hsa00791
hsa00830
hsa00860
hsa00900
hsa00902
hsa00903
hsa00910
hsa00920
hsa00930
hsa00950
hsa00960
hsa00970
hsa00980
hsa00982
hsa00983
hsa01030
hsa01031
hsa01032
hsa01040
hsa01061
hsa01430
hsa01510
hsa02010
hsa03010
hsa03020
hsa03022
hsa03030
hsa03050
hsa03060
hsa03320
hsa03410
hsa03420
hsa03430
hsa03440
hsa03450
hsa04010
hsa04012
hsa04020
Thiamine metabolism
Riboflavin metabolism
Vitamin B6 metabolism
Nicotinate and nicotinamide metabolism
Pantothenate and CoA biosynthesis
Biotin metabolism
Lipoic acid metabolism
Folate biosynthesis
Atrazine degradation
Retinol metabolism
Porphyrin and chlorophyll metabolism
Terpenoid backbone biosynthesis
Monoterpenoid biosynthesis
Limonene and pinene degradation
Nitrogen metabolism
Sulfur metabolism
Caprolactam degradation
Isoquinoline alkaloid biosynthesis
Tropane, piperidine and pyridine alkaloid biosynthesis
Aminoacyl-tRNA biosynthesis
Metabolism of xenobiotics by cytochrome P450
Drug metabolism - cytochrome P450
Drug metabolism - other enzymes
Glycan structures - biosynthesis 1
Glycan structures - biosynthesis 2
Glycan structures - degradation
Biosynthesis of unsaturated fatty acids
Biosynthesis of phenylpropanoids
Cell Communication
Neurodegenerative diseases
ABC transporters
Ribosome
RNA polymerase
Basal transcription factors
DNA replication
Proteasome
Protein export
PPAR signaling pathway
Base excision repair
Nucleotide excision repair
Mismatch repair
Homologous recombination
Non-homologous end-joining
MAPK signaling pathway
ErbB signaling pathway
Calcium signaling pathway
hsa04060
hsa04070
hsa04080
hsa04110
hsa04115
hsa04120
hsa04130
hsa04140
hsa04150
hsa04210
hsa04310
hsa04330
hsa04340
hsa04350
hsa04360
hsa04370
hsa04510
hsa04512
hsa04514
hsa04520
hsa04530
hsa04540
hsa04610
hsa04612
hsa04614
hsa04620
hsa04630
hsa04640
hsa04650
hsa04660
hsa04662
hsa04664
hsa04670
hsa04710
hsa04720
hsa04730
hsa04740
hsa04742
hsa04810
hsa04910
hsa04912
hsa04916
hsa04920
hsa04930
hsa04940
hsa04950
Cytokine-cytokine receptor interaction
Phosphatidylinositol signaling system
Neuroactive ligand-receptor interaction
Cell cycle
p53 signaling pathway
Ubiquitin mediated proteolysis
SNARE interactions in vesicular transport
Regulation of autophagy
mTOR signaling pathway
Apoptosis
Wnt signaling pathway
Notch signaling pathway
Hedgehog signaling pathway
TGF-beta signaling pathway
Axon guidance
VEGF signaling pathway
Focal adhesion
ECM-receptor interaction
Cell adhesion molecules (CAMs)
Adherens junction
Tight junction
Gap junction
Complement and coagulation cascades
Antigen processing and presentation
Renin-angiotensin system
Toll-like receptor signaling pathway
Jak-STAT signaling pathway
Hematopoietic cell lineage
Natural killer cell mediated cytotoxicity
T cell receptor signaling pathway
B cell receptor signaling pathway
Fc epsilon RI signaling pathway
Leukocyte transendothelial migration
Circadian rhythm - mammal
Long-term potentiation
Long-term depression
Olfactory transduction
Taste transduction
Regulation of actin cytoskeleton
Insulin signaling pathway
GnRH signaling pathway
Melanogenesis
Adipocytokine signaling pathway
Type II diabetes mellitus
Type I diabetes mellitus
Maturity onset diabetes of the young
hsa05010
hsa05012
hsa05020
hsa05030
hsa05040
hsa05050
hsa05060
hsa05110
hsa05120
hsa05130
hsa05131
hsa05210
hsa05211
hsa05212
hsa05213
hsa05214
hsa05215
hsa05216
hsa05217
hsa05218
hsa05219
hsa05220
hsa05221
hsa05222
hsa05223
hsa05310
hsa05320
hsa05322
hsa05330
hsa05332
hsa05340
Alzheimer's disease
Parkinson's disease
Prion diseases
Amyotrophic lateral sclerosis (ALS)
Huntington's disease
Dentatorubropallidoluysian atrophy (DRPLA)
Prion disease
Vibrio cholerae infection
Epithelial cell signaling in Helicobacter pylori infection
Pathogenic Escherichia coli infection - EHEC
Shigellosis
Colorectal cancer
Renal cell carcinoma
Pancreatic cancer
Endometrial cancer
Glioma
Prostate cancer
Thyroid cancer
Basal cell carcinoma
Melanoma
Bladder cancer
Chronic myeloid leukemia
Acute myeloid leukemia
Small cell lung cancer
Non-small cell lung cancer
Asthma
Autoimmune thyroid disease
Systemic lupus erythematosus
Allograft rejection
Graft-versus-host disease
Primary immunodeficiency