Lacey Holzer, Richard Tafalla, University of Wisconsin-Stout Abstract 190 550 170 500 The Response of Blood Glucose to Reported Total Fat Intake 140 The Response of Blood Glucose to Reported Total Energy (Kcal) Intake 3500 120 450 R-sq=42.9% P=.021 110 90 70 100 400 350 R-sq=60.9% P=.003 300 R-sq=32.9% P=.051 80 60 250 Total Energy (Kcal) 130 3000 Total Fat (g) Total Carbohydrate (g) 150 Total Protein (g) Background: Elevated fasting blood glucose ranges from normal glucose tolerance (under 100 mg/dL) to impaired glucose tolerance (100-125 mg/dL) to diabetes mellitus (above 126 mg/dL). Glucose intolerance is related to the development of chronic diseases, specifically, metabolic syndrome, obesity, type 2 diabetes, and cardiovascular disease. Current National Institutes of Health statistics conclude that an estimated 1 in 6 Americans have insulin resistance. Dietary intake may have a direct influence on glucose metabolism and insulin sensitivity. The Response of Blood Glucose to Reported Carbohydrate Intake The Response of Blood Glucose to Reported Protein Intake 2000 200 40 50 150 30 100 85 90 95 100 105 110 115 1500 20 85 90 95 100 105 110 115 85 90 Blood Glucose (mg/dL) Blood Glucose (mg/dL) Objective: The purpose of this study was to correlate the result of reported dietary intake to measured fasting blood glucose. R-sq=56.2% P=.005 2500 The Response of Blood Glucose to Reported Total Sugar Intake 100 105 110 115 1000 Blood Glucose (mg/dL) The Response of Blood Glucose to Reported Galactose Intake 1 375 95 85 The Response of Blood Glucose to Reported Lactose Intake 160 95 Glucose (mg/dL) 105 Blood 115 The Response of Blood Glucose to Reported Glucose Intake 65 0.9 175 0.6 R-sq=31.4% P=.046 0.5 0.4 60 Materials and Methods R-sq=55.2% P=.006 35 25 0.3 125 40 0.2 15 75 20 0.1 25 0 85 90 95 100 105 110 115 0 85 90 Blood Glucose (mg/dL) 95 100 105 110 115 5 85 90 Blood Glucose (mg/dL) 95 100 105 110 115 85 90 Blood Glucose (mg/dL) The Response of Blood Glucose to Reported Starch Intake The Response of Blood Glucose to Reported Sucrose Intake 95 100 105 110 115 Blood Glucose (mg/dL) The Response of Blood Glucose to Reported Fructose Intake 175 The Response of Blood Glucose to Reported Maltose Intake 5.5 65 5 70 155 55 4.5 60 135 4 40 115 R-sq=19.9% P=.15 95 R-sq=46.3% P=.015 35 Maltose (g) R-sq=62.9% P=.002 Total Fructose (g) 50 Total Starch (g) Total Sucrose (g) 45 3.5 R-sq=47.9% P=.009 3 DHQ II- The food frequency questionnaire was administered by a registered dietitian. The results were based on the participants’ diet for the past year. 2.5 25 75 30 2 20 55 10 35 85 90 95 100 105 Blood Glucose (mg/dL) 110 115 15 1.5 1 5 85 90 95 100 105 110 115 Blood Glucose (mg/dL) Demographic Conclusions: The reported energy, carbohydrate, fat, and protein intake correlated to fasting blood glucose levels. Reported total sugar intake including, fructose, glucose, sucrose, galactose, lactose, and maltose also directly correlated to fasting blood glucose levels. The reported starch intake did not correlate with fasting blood glucose levels. The results illustrate a correlation between reported macronutrient and total sugar consumption with fasting blood glucose levels. R-sq=33.9% P=.037 80 Total Glucose (g) R-sq=59.8% P=.003 100 Lactose (g) 225 Galactose (g) 45 80 Results: The overall reported total energy intake (P=.005) was statistically significantly correlated to fasting blood glucose. The macronutrients, carbohydrate (P=.003), protein (P=.021), and fat (P=.051) were statistically significantly correlated to fasting blood glucose. The sugars, including total sugar (P=.003), fructose (P=.015), glucose (P=.006), sucrose (P=.002), galactose (P=.046), lactose (P=.037), and maltose (P=.009) were statistically significantly correlated to fasting blood glucose. The reported starch intake (P=.15) was not statistically significantly correlated to fasting blood glucose. 120 0.7 Glucose intolerance can be associated with serious chronic diseases. The most common are metabolic syndrome, obesity, type 2 diabetes, and cardiovascular disease. Normal glucose tolerance is defined as blood glucose under 100 mg/dL, impaired glucose tolerance is defined as blood glucose of 100-125 mg/dL, and diabetes mellitus is defined as blood glucose of 126 mg/dL or greater. Impaired glucose tolerance is rising around the world and many people are being diagnosed with diabetes. AccuChek* - The use of AccuChek by nursing staff determined blood glucose measured in mg/dL 55 0.8 275 Total Sugar (g) Design: Participants (n=12) selected were a subset of “The Glycemic Effect of Honey” study. Recruited individuals exhibited both normal and impaired glucose tolerance. At baseline, fasting blood glucose levels were determined by Accu-Chek (mg/dL). Participants completed the Diet History Questionnaire II (DHQ II) online and the resultant energy, carbohydrate, protein, fat, total sugar, fructose, glucose, sucrose, galactose, lactose, maltose, and starch were used for comparison. Reported nutrient intake was correlated to blood glucose using the fitted line regression on Minitab (version 15). 140 325 Introduction Age (years) Body Mass Index (BMI) Height (cm) Weight (kg) N= Blood Glucose (mg/dL) 85 90 95 100 105 110 115 85 90 95 100 105 Blood Glucose (mg/dL) Blood Glucose (mg/dL) Totalmean(SE) 49.1(3.9) Menmean(SE) 52.3(4.7) Womenmean(SE) 48.0(5.16) 26.9(1.4) 28.2(0.6) 26.8(1.8) 171.1(2.1) 79.1(4.4) 12 179.9(2.9) 91.3(2.7) 3 168.2(1.8) 75.1(5.1) 9 97(2.40) 104(3.84) 94(2.46) 110 115 Conclusion •Reported higher dietary intake of energy, carbohydrates, protein, fat, total sugar, fructose, glucose, sucrose, galactose, lactose, and maltose correlated with a higher fasting blood glucose level. •Starch intake did not correlate with fasting blood glucose. References Costacou T, Mayer-Davis EJ. Nutrition and prevention of type 2 diabetes. AnnRevNutr 2003;23:147-170 Haffner S. The Metabolic Syndrome: inflammation, diabetes mellitus, and cardiovascular disease. AM J Cardiol 2006;97:3-11 National Diabetes Information. (2011, February). Retrieved August 8, 2011, fromNational DiabetesStatistics, 2011: http://www.diabetes.niddk.nih.gov/dm/pubs/statistics/
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