Pathways of Rb+ Influx and Their Relation to Intracellular
[Na+] in the Perfused Rat Heart
by Valerie V. Kupriyanov, Laura C. Stewart, Bo Xiang, June Kwak, and Roxanne
Deslauriers
Circulation Research
Volume 76(5):839-851
May 1, 1995
Copyright © American Heart Association, Inc. All rights reserved.
Left, Representative 87Rb nuclear magnetic resonance spectra of perfused rat heart during Rb+
load and washout.
Valerie V. Kupriyanov et al. Circ Res. 1995;76:839-851
Copyright © American Heart Association, Inc. All rights reserved.
Left, Graph showing kinetics of Rb+ equilibration in extracellular space.
Valerie V. Kupriyanov et al. Circ Res. 1995;76:839-851
Copyright © American Heart Association, Inc. All rights reserved.
Bar graph showing effects of procaine (Proc), ouabain (Ouab), bumetanide (Bum), and 4aminopyridine (4-AP) on the Rb+ uptake rate in perfused rat hearts.
Valerie V. Kupriyanov et al. Circ Res. 1995;76:839-851
Copyright © American Heart Association, Inc. All rights reserved.
Bar graph showing effects of lidocaine (Lido), dimethylamiloride (DMA), and monensin (Mon) on
the Rb+ influx rate in perfused rat hearts.
Valerie V. Kupriyanov et al. Circ Res. 1995;76:839-851
Copyright © American Heart Association, Inc. All rights reserved.
Bar graph showing inhibition of the Rb+ uptake rate in perfused rat hearts with
dimethylamiloride (DMA) and bumetanide (Bum) in the presence of lidocaine (Lido).
Valerie V. Kupriyanov et al. Circ Res. 1995;76:839-851
Copyright © American Heart Association, Inc. All rights reserved.
Changes in the 23Na spectra of perfused rat hearts caused by procaine, ouabain, and monensin.
Valerie V. Kupriyanov et al. Circ Res. 1995;76:839-851
Copyright © American Heart Association, Inc. All rights reserved.
Bar graph showing effect of drugs that alter Rb+ and Na+ transport on intracellular Na+ content
in perfused rat hearts.
Valerie V. Kupriyanov et al. Circ Res. 1995;76:839-851
Copyright © American Heart Association, Inc. All rights reserved.
Graph showing correlation between the Rb+ influx rate and the intracellular Na+ content in
perfused rat hearts.
Valerie V. Kupriyanov et al. Circ Res. 1995;76:839-851
Copyright © American Heart Association, Inc. All rights reserved.