Published in Thyroid. January 2014, 24(1): 88-168.
DOI: 10.1089/thy.2013.0109
© Mary Ann Liebert, Inc.
FIG. 18. Study of the interscapular brown adipose tissue (iBAT) thermal response to norepinephrine (NE) infusion. (A,
B) A rat (or mouse) is anesthetized, and the iBAT pad is exposed through a surgical incision. A thermistor is placed under
the iBAT pad and secured with a stitch; a rectal thermistor is inserted in the colon for measurement of core temperature
(not shown). The right jugular vein is cannulated and connected to an infusion pump for infusion of catecholamines or
other molecules. Temperatures are measured continuously before and during infusion. Courtesy of Dr. Miriam O. Ribeiro.
(C) Plasma NE levels during infusion in intact and Tx rats; (D) iBAT temperature during infusion in intact and Tx rats.
Infusion lasted for 60 minutes, and the temperature data points indicate the difference between baseline and maximum
peak achieved during infusion. Reproduced with permission from Ribeiro et al. (627).