MCUTS Trial: A sport-based intervention to increase uptake of voluntary medical male circumcision among adult male football players: results from a clusterrandomised trial in Bulawayo, Zimbabwe Background VMMC in Zimbabwe* • National target: 80% VMMC coverage by 2015 • HIV-negative men aged 15-29 years • Could avert 570,000 (42%) new HIV infections by 2025 • Roughly 1 infection averted per 4 VMMCs Sport-based HIV prevention** • • • • Strong effects on knowledge, attitudes, behaviour Overall, low-quality studies conducted to date Few studies assessing effects on HIV service uptake GRS conducting two RCTs, planning others * Njeuhmeli (2012) ** Kaufman, Spencer and Ross (2013) in AIDS and Behavior ‘Make The Cut’ Intervention Short, scalable, soccer-based intervention • 60 min session facilitated by circumcised men with soccer teams • Most men play and watch soccer Logistical and behavioural reinforcement • Transport provided • Biweekly SMS reminders • Priority status at clinic MCUTS Trial: Methods Soccer teams randomised into three groups • Delivery by soccer pros (n=15) • Delivery by non-soccer-pros (n=14) • Control group (n=18) Primary outcome: VMMC uptake over 4 months • Clinic register and consent form • Linkage via national ID, name, DOB, age, phone number Baseline surveys using Open Data Kit • Assessing reported MC prevalence, knowledge, intentions MCUTS Trial: Methods MCUTS Trial: Results Round 1 2 3 • Roughly 9.8-times higher odds of VMMC uptake in intervention than control group: OR=9.81, 95% CI=0.93-103.2, p=0.057 Comparing uptake of VMMC between groups, main outcome analysis by intention-to-treat MCUTS Trial: Results Round 3 1 2 • Hints of difference of effectiveness by age • Lower uptake among men over 30 years Comparing VMMC uptake between study groups across age MCUTS Trial: Discussion Round 2 1 • Weak evidence of strong relative effect and modest absolute effect • Smaller sample size than anticipated - Less statistical power than planned • Limited generalizability beyond soccer players • MCUTS II with adolescent males and Weekend Special with adult males Acknowledgements MCUTS Collaborators Zak Kaufman, David Ross, Jeff DeCelles, Kenneth Bhauti, Karin Hatzold, Cynthia Chaibva, & Fennie Mantula Advisor Thomas Clark Implementation Staff Grassroot Soccer Zimbabwe & PSI Zimbabwe Funding Bill & Melinda Gates Foundation Doris Duke Charitable Foundation
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