李庆顺博士简历 工作地址: 厦门大学环境与生态学院 福建、厦门翔安区,361102 E-mail: [email protected] 工作电话: 86-592-218-9836 学历: 理学学士:植物学,厦门大学生物系,1983 理学硕士:生化遗传学,厦门大学生物系,1986 (导师:黄厚哲) 理学博士:植物生物化学与分子生物学,美国肯塔基大学,1995(导师:Arthur Hunt) 博士后:植物分子生物学及生物化学,美国肯塔基大学,1995-1996(导师:Arthur Hunt) 工作经历: 2012-至今: 院长、教授、博导,厦门大学环境与生态学院 2013-2015.6: 教授,迈阿密大学生物学系, 美国俄亥俄州 2011-2013:主任(Director),迈阿密大学细胞、分子与结构生物学硕博研究生点 2010-2013:教授,迈阿密大学植物学系 2010-2014:副理事长、理事长(各两年任期), 美国俄亥俄州植物生物技术协会 2009-2012:副系主任,迈阿密大学植物学系 2007-2010:副教授,迈阿密大学植物学系 2001-2007: 助理教授,迈阿密大学植物学系,美国俄亥俄州 1996-2001:科学研究员(Scientist), 课题负责人,美国肯塔基大学烟草研究发展中心 1995-1996:博士后,美国肯塔基大学,植物分子生物学及生物化学 1989-1991:讲师,厦门大学生物系 1986-1988:助教,厦门大学生物系 专业学会会员及职务: 美国植物生物学会,会员 RNA 学会 (国际核糖核酸学会),会员 美国科学进步协会,会员 全美科学研究协会--SIGMA-XI,会员;迈阿密大学分会,财务员(2005-2008)。 科学荣誉与服务: 1. 肯塔基大学杰出校友,肯塔基大学农学院,2014 2. 杰出学者,迈阿密大学,2012 3. 年度最佳研究者,迈阿密大学 2011, Sigma Xi –全美科学研究协会 4. 中华人民共和国国庆 60 周年特邀 “海外高层次人才和留学回国人员国庆观礼团” 成 员,2009。 5. 中华人民共和国国庆 50 周年特邀 “海外百名博士访问交流团” 成员,1999。 6. 为 38 种专业科学杂志审稿人。 7. 客座教授:福建农科院;上海师范大学;福建农林大学。 代表性科学论文 (近 5 年;学术生涯共 76 篇) 1 Journal articles 1. Xiaohui Wu*, Yong Zeng, Jinting Guan, Guoli, Ji, Rongting Huang, Qingshun Q. Li*. 2015. Genome-wide Characterization of Intergenic Polyadenylation Sites Redefines Gene Spaces in Arabidopsis thaliana. BMC Genomics. 16:511. 2. Guoli Ji, Jinting Guan, Yong Zeng, Qingshun Q. Li and Xiaohui Wu*. 2015. Genome-wide identification and predictive modeling of polyadenylation sites in eukaryotes. Briefings in Bioinformatics. 16(2): 304-313. 3. Guoli Ji, Lei Li, Qingshun Q. Li, Xiangdong Wu, Jingyi Fu, Xiaohui Wu*. 2015. PASPA: a web server for mRNA poly(A) site predictions in plants and algae. Bioinformatics, 31(10): 1671-3. 4. Jinting Guan, Jingyi Fu, Mingcheng Wu, Longteng Chen, Guoli Ji, Qingshun Q. Li, Xiaohui Wu*. 2015. VAAPA: A web platform for visualization and analysis of alternative polyadenylation. Comput Biol Med. 57:20-25. 5. Man Liu, Ruqiang Xu, Carrie Merrill, Liwei Hong, Carol Von Lanken, Arthur G. Hunt* and Qingshun Q. Li*. 2014. Integration of developmental and environmental signals via a polyadenylation factor in plants. PloS One. 9: e115779. 6. William C Ray*, Samuel L Wolock, Nicholas W Callahan, Min Dong, Qingshun Q. Li, Chun Liang, Thomas J. Magliery and Christopher W. Bartlett. 2014. Addressing the unmet need for visualizing Conditional Random Fields in Biological Data. BMC Bioinformatics. 15:202. 7. Xiaohui Wu, Bobby Gaffney, Arthur G. Hunt*, and Qingshun Q. Li*. 2014. Genome-wide determination of poly(A) sites in Medicago truncatula: evolutionary conservation of alternative poly(A) site choice. BMC Genomics. 15:615. 8. Zhixin Zhao, Xiaohui Wu, Praveen Kumar Raj Kumar, Min Dong, Guoli Ji, Qingshun Q. Li* and Chun Liang*. 2014. Bioinformatics analysis of alternative polyadenylation in green alga Chlamydomonas reinhardtii using transcriptome sequences from three different sequencing platforms. Genes Genomics Genetics (G3). 4:871-883. 9. Liuyin Ma, Pratap Kumar Pati, Man Liu, Qingshun Q. Li* and Arthur G. Hunt*. 2014. High throughput characterizations of poly(A) site choice in plants. Methods. 67:74-83. 10. Liuyin Ma, Cheng Guo and Qingshun Q. Li*. 2014. Role of alternative polyadenylation in epigenetic silencing and antisilencing. Proc. Nat. Acad. Sci. USA, 111:9-10. 11. Denghui Xing, Yajun Wang, Ruqiang Xu, Xinfu Ye, Dewei Yang, Qingshun Q. Li*. 2013. The Regulatory Role of Pcf11-Similar-4 (PCFS4) in Arabidopsis Development by Genome-Wide Physical Interactions with Target Loci. BMC Genomics. 14:598. 12. Guoli Ji*, Yong Zeng, Jinting Guan, Qingshun Q. Li, Congting Ye, Yunlong Liu. 2013. Recent advances in mathematical modeling and simulation of DNA replication process. Current Bioinformatics. 8:591-602. 13. Patrick E. Thomas, Xiaohui Wu, Man Liu, Bobby Gaffney, Guoli Ji, Qingshun Q. Li and Arthur G. Hunt*. 2012. Genome-wide control of poly(A) site choice by CPSF30 in 2 Arabidopsis. Plant Cell. 24: 4376-4388. 14. Arthur G. Hunt, Denghui Xing*, Qingshun Q. Li*. 2012. Plant polyadenylation factors: conservation and variety. BMC Genomics. 13:641. 15. Hongwei Zhao, Jun Zheng, Qingshun Q. Li*. 2011. A novel plant in vitro assay system for pre-mRNA cleavage and polyadenylation. Plant Physiology, 157:1546-1554. 16. Yingjia Shen, R. C. Venu, Kan Nobuta, Xiaohui Wu, Varun Notibula, Caghan Demirci, Blake C Meyers, Guo-Liang Wang, Guoli Ji, Qingshun Q. Li*. 2011. Transcriptome Dynamics Through Alternative Polyadenylation in Developmental and Environmental Responses in Plants Revealed by Deep Sequencing. Genome Research, 21:1478-1486. 17. Xiaohui Wu, Man Liu, Bruce Downie, Chun Liang, Guoli Ji, Qingshun Q. Li*, Arthur Hunt*. 2011. The genome-wide landscape of polyadenylation in Arabidopsis provides evidence for extensive alternative polyadenylation. Proc. Nat. Acad. Sci. USA, 108:12533–12538. 18. Jianti Zheng, Denghui Xing, Xiaohui Wu, Diana Kroll, Yingjia Shen, Guoli Ji, Qingshun Q. Li*. 2011. Ratio-based analysis of differential mRNA processing and expression of a polyadenylation factor mutant pcfs4 using Arabidopsis tiling microarray. PLoS One, 6:e14719. 19. Denghui Xing, Qingshun Q. Li*. 2011. Alternative polyadenylation and gene expression regulation in plants. WIREs (Willey Interdisciplinary Reviews) RNA, 2:445-458. (Invited review) Book Chapters In “Polyadenylation in Plants” Editors: A.G. Hunt and Q.Q. Li. Series: Methods in Molecular Biology; Series Editor: John Walker. Humana Press, Springer Publishing Group, USA. 20. Jingyi Cao, Qingshun Q. Li*. 2015. Poly(A) Tag Library Construction from 10 ng Total RNA. 21. Hongwei Zhao*, Xinfu Ye, Qingshun Q. Li.. 2015. Characterization of plant polyadenylation complexes by using tandem affinity purification. 22. Hongwei Zhao*, Qingshun Q. Li. 2015. In vitro analysis of cleavage and polyadenylation in Arabidopsis. 23. Denghui Xing*, Qingshun Q. Li. 2015. RADPRE: a computational program for identification of differential mRNA processing including alternative polyadenylation. 24. Xiaohui Wu, Guoli Ji, Qingshun Q. Li*. 2015. Computational analysis of plant polyadenylation signals. 25. Xiaohui Wu*, Guoli Ji, Qingshun Q. Li. 2015. Prediction of plant polyadenylation sites. 26. Xiaohui Wu*, Guoli Ji, Qingshun Q. Li. 2015. PAT-seq data processing to extract poly(A) sites and their analysis. 27. Min Dong, Qingshun Q. Li, and Chun Liang*. RNA-seq data. 3 2015. Extraction of poly(A) sites from 28. Man Liu, Xiaohui Wu, Qingshun Q. Li*. 2015. DNA/RNA hybrid primer mediated poly(A) tag library construction for Illumina sequencing. 美国及世界专利(共 5 项): 1. Arthur G. Hunt, Qingshun Q. Li, Jianjun Yang and Carol von Lanken. 2000. Use of yeast poly(A) binding proteins and their genes for broad range protection of plants against bacterial, fungal and viral pathogens. US Patent #6018106. 2. Qingshun Q. Li, Songhai Shen, Arthur G. Hunt and Shengyang He. 2002. Use of hrmA proteins and their genes for broad range protection of plants against bacterial, viral and fungal pathogens. US Patent #6342654 3. Arthur G. Hunt, Glen B. Collins, Qingshun Q. Li, Christopher B. Lawrence and Santanu Dasgupta. 2002. Use of bacterial acetate kinase and their genes for protection of plants against different pathogens. US Patent # 6476293 4. Nicholas P. Everett, Qingshun Q. Li, Christopher Lawrence, H. Maelor Davies. 2007. Peptides with enhanced stability to protease degradation. US Patent #7,214,766. Also International Patent. 5. Dave Francko, Ken Wilson, Qingshun Q. Li, Alejandra Equiza. Plant Cryoprotectant Compositions and Methods of Use. US Patent Application #61/019713 (June 18, 2009), International Patent Application #PCT/US08/67241. (这项植物防冻剂专利已经用于商业 生产并在市场销售 (“Freezepruf” http://www.liquidfence.com/FreezePruf.html) 出版书: 1. Arthur G. Hunt and Qingshun Q. Li, Editors. 2015. Book title: Polyadenylation in Plants. Series title: Methods of Molecular Biology. Humana Press, USA (part of the Springer publishing group). 2. Rebecca S. Balish, Qingshun Q. Li, and David Pennock. 2012. Laboratory Experiences for Biological Concepts: Structure, Function, Cellular and Molecular Biology. ISBN 978-0-7380-4797-3. Hayden McNeil Publishing, Plymouth, Michigan, USA. 应邀国际学术会议报告(与其他学术讲座及学术会议报告一共 50 多次): 国际、国内、区域性学术会议摘要与版报(共 100 余次) 4
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