Questions for preparation. Final test “Bioenergetics. Carbohydrates”
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Question and answer variants
Choose expression which is correct for description of the 1 st phase of catabolism:
1. 1/3 of energy is released in the reactions of this phase;
2. Millions of different compounds may enter this phase;
3. Carbon dioxide and water are released in the reactions of this stage.
4. The process of bonds cleavage may be catalysed by 5 different ways;
Choose expression which is correct for description of the 1 st phase of catabolism:
1. No energy is accumulated in the reactions of this phase;
2. Only 5 compounds may enter this phase;
3. NH3 and creatinine are released in the reactions of this stage as end products.
4. Carbon dioxide and water are released in the reactions of this stage.
Choose expression which is correct for description of the 1 st phase of catabolism:
1. Most of ATP is synthesised in this phase;
2. 1/3 of energy is released in the reactions of this phase;
3. The process of bonds cleavage is catalysed by hydrolases and phosphorylases;
4. Only 5 compounds may enter this phase;
Choose expression which is correct for description of the 2 nd phase of catabolism:
1. 1/3 of energy is released in the reactions of this phase;
2. Millions of different compounds may enter this phase;
3. Only 5 compounds may enter this phase;
4. No energy is accumulated in the reactions of this phase;
Choose expression which is correct for description of the 2 nd phase of catabolism:
1. 50% of energy is released in the reactions of this phase;
2. Millions of different compounds may enter this phase;
3. Only 5 compounds may enter this phase;
4. The process of bonds cleavage may be catalysed by 5 different ways;
Choose expression which is correct for description of the 2 nd phase of catabolism:
1. 2/3 of energy is released in the reactions of this phase;
2. Only 5 compounds may enter this phase;
3. No energy is accumulated in the reactions of this phase;
4. NH3 and carbon dioxide are released in the reactions of this stage as end products;
Choose expression which is correct for description of the 3rd phase of catabolism:
1. 2/3 of energy is released in the reactions of this phase;
2. Millions of different compounds may enter this phase;
3. NH3 and creatinine are released in the reactions of this stage as end products.
4. The process of bonds cleavage may be catalysed by 5 different ways;
Choose expression which is correct for description of the 3 rd phase of catabolism:
1. 50% of energy is released in the reactions of this phase;
2. Catabolic reactions of this phase produce most of ATP in the cell;
3. NH3 and creatinine are released in the reactions of this stage as end products.
4. The process of bonds cleavage is catalysed by hydrolases and phosphorylases;
Choose expression which is correct for description of the 3 rd phase of catabolism:
1. 1/3 of energy is released in the reactions of this phase;
2. NH3 and creatinine are released in the reactions of this stage as end products.
3. Carbon dioxide and water are released in the reactions of this stage.
4. The process of bonds cleavage may be catalysed by 5 different ways;
Choose expression which is correct for description of the 3 rd phase of catabolism:
1. 1/3 of energy is released in the reactions of this phase;
2. Main metabolic pathways of this phase are Krebs cycle and respiratory chain;
3. No energy is accumulated in the reactions of this phase;
4. NH3 and creatinine are released in the reactions of this stage as end products.
In Krebs cycle regulatory enzyme is…
1. Aconitase
2. Citrate synthase
3. Succinyl-CoA synthase (succinate thiokinase)
4. Malate dehydrogenase
In Krebs cycle regulatory enzyme is…
1. Fumarase
2. Aconitase
3. Isocitrate dehydrogenase
4. Malate dehydrogenase
In Krebs cycle regulatory enzyme is…
1. Alfa-ketoglutarate dehydrogenase complex
2. Succinyl-CoA synthase (succinate thiokinase)
3. Aconitase
4. Malate dehydrogenase
In Krebs cycle regulatory enzyme is…
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1. Fumarase
2. Aconitase
3. Malate dehydrogenase
4. Succinate dehydrogenase
Enzyme which catalyse irreversible reaction of Krebs cycle is…
1. Alfa-ketoglutarate dehydrogenase complex
2. Succinyl-CoA synthase (succinate thiokinase)
3. Malate dehydrogenase
4. Aconitase
Enzyme which catalyse irreversible reaction of Krebs cycle is…
1. Aconitase
2. Malate dehydrogenase
3. Citrate synthase
4. Succinyl-CoA synthase (succinate thiokinase)
In Krebs cycle enzyme which catalyse FAD-dependent dehydrogenation is…
1. Fumarase
2. Aconitase
3. Malate dehydrogenase
4. Succinate dehydrogenase
In Krebs cycle enzyme whose activity is regulated by covalent modification is…
1. Malate dehydrogenase
2. Succinate dehydrogenase
3. Succinyl-CoA synthase (succinate thiokinase)
4. Alfa-ketoglutarate dehydrogenase complex
In Krebs cycle enzyme whose activity may be downregulated by competitive inhibition is…
1. Fumarase
2. Isocitrate dehydrogenase
3. Succinate dehydrogenase
4. Malate dehydrogenase
In Krebs cycle enzyme whose activity may be downregulated by allosteric inhibition by citrate is…
1. Isocitrate dehydrogenase
2. Citrate synthase
3. Succinate dehydrogenase
4. Malate dehydrogenase
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
substrate:
1. fumarase, fumaric acid
2. aconitase, citrate
3. isocitrate dehydrogenase, isocitrate
4. succinate dehydrogenase, succinate
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
substrate:
1. succinate dehydrogenase, succinate
2. malate dehydrogenase, malate
3. citrate synthase, oxaloacetate
4. succinyl-CоА-synthase, α-ketoglutarate
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
product:
1. succinate dehydrogenase, fumarate
2. succinate-thiokinase, succinate
3. isocitrate dehydrogenase, -ketoglutarate
4. -ketoglutarate dehydrogenase complex, succinyl-CоА
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
product:
1. fumarase, malate
2. isocitrate dehydrogenase, α-ketoglutarate
3. succinate dehydrogenase, fumaric acid
4. malate dehydrogenase, oxaloacetate
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
product:
1. Fumarase, malate
2. Isocitrate dehydrogenase, α-ketoglutarate
3. Succinate dehydrogenase, fumaric acid
4. Malate dehydrogenase, oxaloacetate
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
product:
1.
fumarase, fumaric acid
2.
aconitase, isocitrate
3.
isocitrate dehydrogenase, isocitrate
4.
succinate dehydrogenase, succinate
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For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
cofactor:
1.
isocitrate dehydrogenase, NAD+
2.
succinate dehydrogenase, FAD
3.
-ketoglutarate dehydrogenase complex, NAD+
4.
malate dehydrogenase, NAD+
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
cofactor:
1.
isocitrate dehydrogenase, NAD+
2.
succinate dehydrogenase, FAD
3.
-ketoglutarate dehydrogenase complex, NAD+
4.
malate dehydrogenase, NAD+
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
cofactor:
1.
isocitrate dehydrogenase, NAD+
2.
succinate dehydrogenase, FAD
3.
-ketoglutarate dehydrogenase complex, NAD+
4.
malate dehydrogenase, NAD+
For reaction number  from the scheme of Krebs cycle choose correct combination of names of enzyme and its
cofactor:
1.
isocitrate dehydrogenase, NAD+
2.
succinate dehydrogenase, FAD
3.
-ketoglutarate dehydrogenase complex, NAD+
4.
malate dehydrogenase, NAD+
Substance, which inhibit NADH-CoQ oxydoreductase complex is…
1. Rotenon
2. Cyanide
3. Antimycin
4. Carbon monoxide
Substance, which inhibit NADH-CoQ oxydoreductase complex is…
1. Cyanide
2. Carboxin
3. Phenobarbital
4. Antimycin
Substance, which inhibit succinate-CoQ oxydoreductase complex is…
1. Antimycin
2. Carboxin
3. Cyanide
4. Carbon monoxide
Substance, which inhibit CoQH2-cytochrome c oxydoreductase complex is…
1. Rotenon
2. Phenobarbital
3. Antimycin
4. Cyanide
Substance, which inhibit cytochrome c oxydase complex is…
1. Carbon monoxide
2. Antimycin
3. Carboxin
4. Rotenon
Substance, which inhibit cytochrome c oxydase complex is…
1. Antimycin
2. Phenobarbital
3. Carboxin
4. Cyanide
Choose correct combination of respiratory complex name and its structural components:
1. NADH-CoQ oxydoreductase complex, [FMN-containing flavoprotein, iron-sulfur proteins]
2. NADH-CoQ oxydoreductase complex, [FAD-containing flavoprotein, iron-sulfur protein]
3. NADH-CoQ oxydoreductase complex, [cyt b, iron-sulfur protein, cyt c1]
4. NADH-CoQ oxydoreductase complex, [cyt a, cyt a3]
Choose correct combination of respiratory complex name and its structural components:
1. succinate-CoQ oxydoreductase complex, [FMN-containing flavoprotein, iron-sulfur proteins]
2. succinate-CoQ oxydoreductase complex, [cyt b, iron-sulfur protein, cyt c1]
3. succinate-CoQ oxydoreductase complex, [cyt a, cyt a3]
4. succinate-CoQ oxydoreductase complex, [FAD-containing flavoprotein, iron-sulfur protein]
Choose correct combination of respiratory complex name and its structural components:
1. CoQH2-cytochrome c oxydoreductase complex, [cyt a, cyt a3]
2. CoQH2-cytochrome c oxydoreductase complex, [cyt b, iron-sulfur protein, cyt c1]
3. CoQH2-cytochrome c oxydoreductase complex, [FMN-containing flavoprotein, iron-sulfur proteins]
4. CoQH2-cytochrome c oxydoreductase complex, [FAD-containing flavoprotein, iron-sulfur protein]
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Choose correct combination of respiratory complex name and its structural components:
1. cytochrome c oxydase complex, [FAD-containing flavoprotein, iron-sulfur protein]
2. cytochrome c oxydase complex, [FMN-containing flavoprotein, iron-sulfur proteins]
3. cytochrome c oxydase complex, [cyt a, cyt a3]
4. cytochrome c oxydase complex, [cyt b, iron-sulfur protein, cyt c1]
Choose correct value for P/O coefficient if electron donor for respiratory chain is NADH:
1. P/O=1
2. P/O=1,5
3. P/O=2,5
4. P/O=4
Choose correct value for P/O coefficient if electron donor for respiratory chain is FADH2:
1. P/O=1
2. P/O=1,5
3. P/O=2,5
4. P/O=4
Choose correct value for P/O coefficient if electron donor for respiratory chain is ascorbate:
1. P/O=1
2. P/O=1,5
3. P/O=2,5
4. P/O=4
Choose correct value for energetical effect of acetyl-CoA oxidation in Krebs cycle:
1. 3 ATP
2. 6 ATP
3. 10 ATP
4. 15 ATP
Enzyme of Krebs cycle which catalyse reaction in which GTP is formed is…
1. succinate dehydrogenase
2. malate dehydrogenase
3. citrate synthase
4. succinyl-CоА-synthase
Krebs cycle reaction in which GTP is formed is…
1. succinate dehydrogenase reaction
2. succinate thiokinase reaction
3. citrate synthase reaction
4. malate dehydrogenase reaction
Choose correct value for energetical effect of Krebs cycle reaction  (on scheme):
1. 1 ATP
2. 1,5 ATP
3. 2,5 ATP
4. 4 ATP
Choose correct value for energetical effect of Krebs cycle reaction  (on scheme):
1. 4 ATP
2. 2,5 ATP
3. 1,5 ATP
4. 1 ATP
Choose correct value for energetical effect of Krebs cycle reaction  (on scheme):
1. 4 ATP
2. 2,5 ATP
3. 1,5 ATP
4. 1 ATP
Choose correct value for energetical effect of Krebs cycle reaction  (on scheme):
1. 4 ATP
2. 2,5 ATP
3. 1,5 ATP
4. 1 ATP
In mitochondria the rate of substrates oxidation is increased after addition of…
1. Glucose
2. 2,4-dinitrophenol
3. Ascorbic acid
4. Carbon monoxide
In mitochondria the rate of substrates oxidation is increased after addition of…
1. Cyanides
2. Carboxin
3. Carbon monoxide
4. Chlorophenols
In mitochondria oxygen consumption is increased after addition of…
1. Cyanides
2. Carboxin
3. Chlorophenols
4. Carbon monoxide
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In mitochondria heat production is increased after addition of…
1. High amount of acetylsalicylic acid
2. High amount of glucose
3. High amount of NAD+
4. High amount of FADH2
In mitochondria P/O is decreased as a result of action of…
1. Citrate
2. Carbon monoxide
3. Carbon dioxide
4. Carboxin
In mitochondria P/O is decreased as a result of action of…
1. Polynitrophenols
2. Fumarate
3. ADP
4. Oxygen
Action of uncoupling agents is accompanied with…
1. Decrease of rate of substrate oxidation
2. Decrease of oxygen consumption
3. Decrease of P/O value
4. Decrease of heat production
Action of uncoupling agents is accompanied with…
1. Increase of rate of substrate oxidation
2. Decrease of oxygen consumption
3. Increase of P/O value
4. Decrease of heat production
Action of uncoupling agents is accompanied with…
1. Decrease of rate of substrate oxidation
2. Increase of oxygen consumption
3. Increase of P/O value
4. Decrease of heat production
Action of uncoupling agents is accompanied with…
1. Decrease of rate of substrate oxidation
2. Decrease of oxygen consumption
3. Increase of P/O value
4. Increase of heat production
Hypoenergetical state (low ATP production) may be induced by…
1. Niacin deficiency
2. Excess of glucose in food
3. Ca deficiency
4. Vitamin A deficiency
Hypoenergetical state (low ATP production) may be induced by…
1. Vitamin D deficiency
2. Exccess of proteins in food
3. Na deficiency
4. Riboflavin deficiency
Hypoenergetical state (low ATP production) may be induced by…
1. Vitamin E deficiency
2. Ca deficiency
3. Pantothenic acid deficiency
4. Excess of fats in food
Hypoenergetical state (low ATP production) may be induced by…
1. Ca deficiency
2. Starvation
3. Excess of glucose in food
4. Vitamin A deficiency
Hypoenergetical state (low ATP production) may be induced by…
1. Antioxidants deficiency
2. Exccess of proteins in food
3. Na deficiency
4. Long-term heavy physical activity
Hypoenergetical state (low ATP production) may be induced by…
1. Vitamin E deficiency
2. Ca deficiency
3. Decreased oxygen consumption
4. Excess of fats in food
Hypoenergetical state (low ATP production) may be induced by…
1. Excess of glucose in food
2. Action of uncoupling agents
3. Ca deficiency
4. Vitamin A deficiency
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Hypoenergetical state (low ATP production) may be induced by…
1. Vitamin D deficiency
2. Na deficiency
3. Exccess of proteins in food
4. Action of inhibitors of mitochondrial respiratory chains
Hypoenergetical state (low ATP production) may be induced by…
1. Low amount of oxygen in the air
2. Vitamin E deficiency
3. Ca deficiency
4. Excess of fats in food
Hypoenergetical state (low ATP production) may be induced by…
1. Methemoglobin accumulation in blood
2. Excess of glucose in food
3. Ca deficiency
4. Vitamin A deficiency
Microsomal oxidation function is…
1. Energetical (ATP synthesis)
2. Inactivation of xenobiotics
3. Synthesis of proteins
4. Catabolism of glucose
Function of microsomal oxidation is…
1. Energetical (ATP synthesis)
2. Synthesis of proteins
3. Synthesis of bile acids, steroid hormons
4. Catabolism of glucose
Function of microsomal oxidation is…
1. Catabolism of several aromatic aminoacids
2. Energetical (ATP synthesis)
3. Catabolism of glucose
4. Catabolism of proteins
Scheme SH2+O2 → Sox + H2O2 represents action of…
1. Anaerobic dehydrogenase
2. Aerobic dehydrogenase
3. Monooxygenase
4. Dioxygenase
Scheme SH2+O2 → S=O + H2O represents action of…
1. Anaerobic dehydrogenase
2. Aerobic dehydrogenase
3. Monooxygenase
4. Dioxygenase
Scheme SH+O2+XH2 → S-OH + H2O +Xox represents action of…
1. Anaerobic dehydrogenase
2. Aerobic dehydrogenase
3. Monooxygenase
4. Dioxygenase
Scheme SH2+NAD+ → Sox + NADH+H+ represents action of…
1. Anaerobic dehydrogenase
2. Aerobic dehydrogenase
3. Monooxygenase
4. Dioxygenase
Hydrogen peroxide is formed as a result of activity of…
1. Anaerobic dehydrogenases
2. Aerobic dehydrogenases
3. Monooxygenases
4. Dioxygenases
Choose enzyme which participates in inactivation of H2O2:
1. Oxidase
2. Catalase
3. Cytochrome
4. Anaerobic dehydrogenase
Choose enzyme which participates in inactivation of H2O2:
1. Peroxidase
2. Superoxide dismutase
3. Cytochrome
4. Aerobic dehydrogenase