TAGRAVITTM A2
TAGRAVIT™ A2
Tagravit™ A2 microcapsules, enable optimal isolation
and protection of Retinyl palmitate, with unique
Release on Demand™ (RND™) technology that
ensures efficient delivery.
Retinyl palmitate is one of the most important
vitamins for the appearance of the skin. Retinyl
palmitate is an exfoliator which increase shedding rate
of the upper dermal layer forces the skin to produce
new cells. It also provides effective antioxidant
support and regeneration and has been shown in UVB
exposure studies to offer sun protection all by itself.
Its regular application significantly improves the skin
elasticity, smoothness, softness, resulting in younger,
clearer and healthier looking skin.
Retinyl palmitate is highly sensitive and unstable
active ingredient.. Therefore, it is essential to increase
the its stability and overcome formulations barriers
(e.g. handling, packaging and storage).
Technology
In order to ensure retinyl palmitate stability, Tagra
Biotechnologies Ltd. has developed Tagravit™ A2
(Fig.1), a unique microcapsules made by the patented
RND™ technology to enhance retinyl palmitate
stability.
Color: light yellow
Average particle size: less than 70 µm
Storage: closed containers, <10° C.
Shelf Life: 1 year
Solubility: Dispersible in all types of cosmetic
formulations
Moisture: <3%
Formulation
Easy to handle, Tagravit™ A2 is suitable for all types
of formulations*. The Tagravit™ A2 should be added
on the last step of the formulation preparation using
low sheer paddle mixer (60-200rpm).
* Formulations should not contain more than 20% of
alcohols and/or glycols in total.
TAGRAVIT™ A2 enhance retinyl palmitate
stability
Tagravit™ A2 microcapsule shell is made of a single
layer polymer, enabling optimal isolation of the
retinyl palmitate and prevents interaction with other
components. The retinyl palmitate is protected from
light, temperature, pH, and oxidation.
The retinyl palmitate is released from the
microcapsules by rubbing the formulation into the
skin. Until the moment of application, it remains fresh
and potent, due to its high and improved stability. The
Tagravit™ A2 significantly increase the retinyl
palmitate stability (Fig.2).
Fig.1: SEM micrograph of Tagravit ™ A2
microcapsules. Magnification: (A.) 5K / bar- 1µm
and (B.) 1K / bar - 10 µm.
Applications
- Anti-aging
- Nourishing
- Moisturizing
- Wrinkle reduction
- Skin regeneration
- Anti-acne
- Whitening
- Sun protection against UVB
INCI:
Retinyl Palmitate & BHT & Tricaprylin &
Polymethyl Methacrylate .
Product Specification:
Appearance: Powder
Payload: 7% (127272 IU/g)
Fig.2: Stability of Tagravit™ A2 incorporated in
O/W cream base at 25°C compared to free retinyl
palmitate. Data are represented as mean content % of
initial.