Programme
Sunday, 13th October 2013
12:30 – 15:00
REGISTRATION
12:30 – 18:00
DISPLAYING THE POSTERS
15:00 – 15:30
Coffee/tea
15:30 – 15:40
Opening ceremony
Chairpersons:
Ľudmila Šabová, PhD. & Pavel Rössner Jr., PhD.
15:40 – 16:10
Katarína Kozics, Annamária Srančíková, Martina Melušová,
Pavol Mučaji, Vladimír Meluš, Mária Poláková, Zdenka
Krajčovičová, Barbara Kusznierewicz, Eva Horváthová
Effects of Lamiaceae plants on oxidant-induced DNA damage and
antioxidant status in experimental systems in vitro and ex vivo (L1)
16:10 – 16:40
Eva Horváthová, Annamária Srančíková, Martina Melušová,
Darina Slameňová, Katarína Kozics
Effects of Lavandula angustifolia administration on oxidant-induced
DNA damage and antioxidant status in HepG2 cells (in vitro) and in
primary rat hepatocytes (ex vivo) (L2)
16:40 – 17:10
Andrea Rossnerova, Zuzana Novakova, Katerina Honkova,
Milada Spatova, Michal Vojtisek, Radim J. Sram, Pavel
Rossner Jr., Jan Topinka
Possibility of automated scoring micronuclei in adherent human cell
lines by the MetaSystems Metafer image cytometry system for
evaluation of the genetic toxicity (L3)
17:10 – 17:40
Ivona Závacká, Hana Lehocká, Jana Vavrošová, Vladimír
Janout
The results of interconnection of the Evidence of Professional
Exposure to Genotoxic Factors and Cancer Registry in Moravian Silesian Region (Evaluation of occupational exposure to genotoxic
factors in relation to cancer) (L4)
18:00 – 18:30
Welcome drink
18:30
Dinner
Monday, 14th October 2013
Chairpersons:
Katarína Luciaková, D.Sc. & Dr. Jan Topinka, D.Sc.
9:00 – 9:15
Ján Sedlák, D.Sc., director of the Cancer Research Institute, SAS
Welcome speech
9:15 – 10:00
Július Brtko, Lucia Bialešová, Vladimír Lenko, Dana Macejová
The road to nuclear receptors and their cognate ligands: Insights
into physiology and therapy of malignant diseases (L5)
10:00 – 10:30
Ľudmila Šabová, Miroslava Kretová, Katarína Luciaková
The role of NF1 transcription factor in gene regulation (L6)
10:30 – 11:00
Coffee/tea
11:00 – 11:30
Miroslava Kretová, Ľudmila Šabová, Katarína Luciaková
The role of trancription factor NFI in senescence (L7)
11:30 – 12:00
Mária Ficková, Zuzana Kováčiková, Dana Macejová, Július
Brtko
The effect of Bisphenol A in combination with estradiol on the
activity of antioxidant enzymes in human breast carcinoma cells
(L8)
12:30 – 12:50
Eva Regendová-Sedlačková, Katarína Kozics, Michal Pastorek,
Alena Gábelová
UVA-induced damaging potential of 7H-dibenzo[c,g]carbazole (L9)
13:00 – 14:30
Lunch
Chairpersons:
Dr. Mária Ficková, DSc. & Dr. Ivan Chalupa, Ph.D.
14:30 – 15:00
Helena Líbalová, Simona Krčková, Kateřina Uhlířová, Jiří
Kléma, Alena Milcová, Jana Schmuczerová, Miroslav Machala,
Radim J. Šrám, Jan Topinka
Major toxic events and complex molecular response in A549 cells
induced by organic extracts from respirable air particles (L10)
15:00 – 15:30
Pavel Rossner, Jr., Elena Tulupova, Andrea Rossnerova,
Helena Libalova, Hans Gmuender, Katerina Uhlirova, Jan
Topinka, Radim J. Sram
Gene expression profiling in a population exposed to heavy air
pollution (L11)
15:30 – 15:50
Jitka Pavlíková, Jana Schmuczerová, Alena Milcová, Pavel
Rossner, Andrea Rossnerová, Zuzana Nováková, Antonín
Ambrož, Martin Pechout, Michal Vojtíšek, Jan Topinka
Toxicity of diesel emissions under severe congestion simulated in
the laboratory (L12)
15:50 – 16:20
Coffee/tea
POSTER SESSION (5 min. + 5 min. discussion)
16:20 – 16:30
Dana Macejová, Lucia Bialešová, Tomáš Havránek, Július
Brtko, Mária Ficková
Di(2-ethylhexyl)-phthalate: Effects on expression of RXRalpha and
RXRbeta retinoid X receptor subtypes in the MCF-7 breast cancer
cell line (P1)
16:30 – 16:40
Monika Záškvarová, Boris Bilčík, Pavel Výboh, Ivan Čavarga,
Dušan Chorvát, Alžbeta Chorvátová, Pavol Miškovský
Chorioallantoic membrane of Japanese quail embryo as a model
for the study of angiogenesis and cancer treatment (P2)
16:40 – 16:50
Roman Moravčík, Andrej Boháč, Miroslav Kubeš, Michal
Zeman
Inhibition of VEGF mediated post receptor signaling pathways by
newly synthesized tyrosine kinase inhibitor in comparison with
approved multikinase inhibitor sunitinib (P3)
16:50 – 17:00
Katarína Koňariková, Georgios A. Perdikaris, Lucia
Andrezálová, Lucia Laubertová, Helena Gbelcová, Zdeňka
Ďuračková, Ingrid Žitňanová
Influence of N-salicylidene-L-glutamato copper (II) complex on
human colon carcinoma cell line HT-29 and breast carcinoma cell
line MCF-7 (P4)
17:00 – 17:10
Andrej Gajdoš, Dagmar Gajdošová
Mutagenesis modified by lifestyle factors and the cancer prevention
consulting center (P5)
17:10 – 17:20
Lucia Bialešová, Július Brtko, Slavomíra Ondková, Štefan
Galbavý, Dana Macejová
Selected nuclear receptors expression in human breast carcinoma
tissues (P6)
17:20 – 17:30
Hana Svobodová, Petr Jošt, Rudolf Štětina
Potential genotoxicity of the co-administration of prophylactic drugs
against nerve agents (P7)
17:30 – 17:40
Michal Šelc, Martina Neboháčová
Charakterization of DNA-binding protein Tbf1 in yeast Candida
parapsilosis (P8)
18:00 –
Dinner
19:30 –
Slovak wine degustation
Tuesday, 15th October 2013
Chairpersons:
Hana Lehocká, MD., Ph.D. & Július Brtko, DSc.
9:00 – 9:45
Karol Mičieta, Andrea Sámelová, Jozef Dušička, Eva Brutovská
Phytoindication of ecogenotoxicity in the proximity of Chemko
Strážske (L12)
9:45 – 10:05
Eva Brutovská, Andrea Sámelová, Karol Mičieta
The use of plant specific locus systems in tests of genotoxicity
(L13)
10:05 – 10:35
Coffee/tea
10:35 – 10:55
Jana Feruszova, Elička Gálová, Andrea Šoltýsová, Peter Ditte,
Andrea Ševčovičová, Petronela Imreová, Ivan Chalupa, Eva
Miadoková
Comparison of the non-photoactivated and photoactivated hypericin
effects (L14)
10:55 – 11:15
Petronela Imreova, Zuzana Csanyiová, Jana Feruszová, Eliška
Gálová, Andrea Ševčovičová, Eva Miadoková, Lívia Šebová,
Ivan Chalupa
Cytogenetic study of potential genotoxic effect of hypericin in vitro
(L15)
11:15 – 11:35
Martina Melušová, Soňa Jantová, Eva Horváthová
Rosemary essential oil as a potential DNA-protective natural
compound effective against selected oxidative agents in HepG2
cells (L16)
11:35 – 11:55
Annamária Srančíková, Alena Gábelová, Katarína Kozics
Sustained ERK1/2 activation can underlie the cell cycle arrest in
HepG2 cells treated with plant extracts from Salvia officinalis and
Thymus vulgaris (L17)
11:55 – 12:05
Jana Feruszová, Eliška Gálová, Andrea Šoltýsová, Peter Ditte,
Andrea Ševčovičová, Petronela Imreová, Ivan Chalupa, Eva
Miadoková
Biological effects of hypericin and hyperforin (P9)
12:05 – 13:00
Lunch
13:10
Social programme
1. The limestone cave “DRINY”
Departure at 13:10
Around 1 h walking tour through the forest
admission at 14:30 (the last one since it is out of season)
admission fee: 5 Eur
Individual walking tours
2. Dolina Hlboče
3. Havrania skala
4. Molpír hradisko
5. Ostrý kameň
6. Záruby
17:00 – 19:00
Poster discussion
19:00
Conference dinner
Wednesday, 16th October 2013
Chairpersons:
Dr. Alena Gábelová, Ph.D. & Prof. Karol Mičieta, DSc.
9:00 – 9:45
Pavel Vodička, Jana Slysková, Rudolf Štětina, Ľudmila
Vodičková, Pavel Procházka, Miroslav Levy, Veronika
Poláková, Barbara Pardini, Ludovít Bielik, Michaela
Schneiderová, Václav Liska, Andrew Collins, Rajiv Kumar,
Alessio Naccarati
DNA repair characteristics in exposed individuals and in colorectal
cancer patients (L18)
9:45 – 10:15
Ľudmila Vodičková, Maura Carrai, Jana Slyskova, Pavel
Prochazka, Ludovit Bielik, Sona Vodenkova, Katerina
Jiraskova, Alexandra Rejhova, Veronika Vymetalkova,
Riccardo Flamini, Mirko De Rosso, Antonio Dalla Vedova, Luigi
Bavaresco, Pavel Vodička, Roberto Barale
Taste receptor gene variants and taste perception as tentative risk
determinants of colorectal cancer (L19)
10:15 – 10:45
Coffee Break
10:45 – 11:15
Alena Gábelová, Monika Mesárošová, Vlasta Závišová, Martina
Koneracká, Monika Ursínyová, Ivan Chalupa, Katarína Kozics,
Barbora Buliaková, Natália Tomašovičová, Martina Labudová,
Ivo Vávra, Zuzana Križanová, Zuzana Hušeková, Milan Timko,
Fedor Čiampor
The interactions of surface modified magnetite nanoparticles with
human cells; an in vitro study (L20)
11:15 – 11:35
Barbora Buliaková, Monika Mesárošová, Michal Šelc,
Miroslava Kretová, Alena Gábelová
The surface-modified magnetite nanoparticles induce ERK1/2,
SAPK/JNK and p53 phosphorylation in A549 cells (L21)
11:35
Closing ceremony
12:00 – 13:00
Lunch
13:30
Bus departure