PUBLICATIONS
Lu, J., Zhang, L., Lewis, R.S., Bovet, L., Goepfert, S., Jack, A.M., Crutchfield, J.D., Huihua, J.
and Dewey, R.E. 2016. Expression of a constitutively active nitrate reductase variant in
tobacco reduces tobacco-specific nitrosamine accumulation in cured leaves and cigarette
smoke. Plant Biotech. J. 14: 1500-1510.
Lewis, R.S., Lopez, H.O., Bowen, S.W., Andres, K.R., Steede, W.T. and Dewey, R.E. 2015.
Transgenic and mutation-based suppression of a Berberine Bridge Enzyme-Like (BBL)
gene family reduces alkaloid content in field-grown tobacco. PLOS ONE
10(2):e0117273.
Patel, M., Milla-Lewis, S., Zhang, W., Templeton, K., Reynolds, W.C., Richardson, K., Biswas,
M., Zuleta, M.C., Dewey, R.E., Qu, R. and Sathish, P. 2015. Overexpression of ubiquitinlike LpHUB1 gene confers drought tolerance in perennial ryegrass. Plant Biotech. J. 13:
689-699.
Dewey, R.E. and Lewis, R.S. (2014) Molecular biology-based approaches for facilitating
compliance of future tobacco products in an FDA regulatory environment. Recent Adv.
Tob. Sci. 40: 47-62.
Cardinal, A.J., Whetten, R., Wang, S., Auclair, J., Hyten, D., Cregan, P., Bachlava, E., Gillman,
J., Rameriz, M., Dewey, R., Upchurch, G., Miranda, L. and Burton, J.W (2014) Mapping
the low palmitate fap1 mutation and validation of its effects in soybean oil and agronomic
traits in three soybean populations. Theor. Appl. Genet. 127: 97-111.
Cai, B., Jack, A.M., Lewis, R.S., Dewey, R.E. and Bush, L.P. (2013) (R)-nicotine biosynthesis,
metabolism and translocation in tobacco as determined by nicotine demethylase mutants.
Phytochem. 95: 188-196.
Patel, M., Dewey, R.E. and Qu, R. (2013) Enhancing Agrobacterium tumefaciens-mediated
transformation efficiency of perennial ryegrass and rice using heat and high maltose
treatments during bacterial infection. Plant Cell Tiss. Organ Cult. 114: 19-29.
Dewey, R.E. and Xie, J. (2013) Molecular genetics of alkaloid biosynthesis in Nicotiana
tabacum. Phytochem. 94: 10-27.
Zhang, W-J., Dewey, R.E., Boss, W., Phillippy, B.Q. and Qu, R. (2013) Enhanced
Agrobacterium-mediated transformation efficiencies in monocot cells is associated with
attenuated defense responses. Plant Mol. Biol. 81: 273-286.
Cai, B., Siminszky, B., Chappell, J., Dewey, R.E. and Bush, L.P. (2012) Enantioselective
demethylation of nicotine as a mechanism for variable nornicotine composition in
tobacco leaf. J. Biol. Chem. 287: 42804-42811.
Li, D., Lewis, R.S., Jack, A.M., Dewey, R.E., Bowen, S.W. and Miller, R.D. (2012)
Development of CAPS and dCAPS markers for CYP82E4, CYP82E5v2 and CYP82E10
gene mutants reducing nicotine to nornicotine conversion in tobacco. Mol. Breed. 29:
589-599.
De Vries, B.D., Fehr, W.R., Welke, G.A. and Dewey, R.E. (2011) Molecular analysis of the
mutant alleles for elevated palmitate concentration in soybean. Crop Sci. 51: 2554-2560.
Cardinal, A.J., Burton, J.W., Camacho-Roger, A.M., Whetten R., Chappell, A.S., Bilyeu, K.D.,
Auclair, J. and Dewey, R.E. (2011) Molecular analysis of GmFAD3A in two soybean
populations segregating for the fan, fap1, and fapnc loci. Crop Sci. 51: 2104-2112.
De Vries, B.D., Fehr, W.R., Welke, G.A. and Dewey, R.E. (2011) Molecular characterization of
the mutant fap3(A22) allele for reduced palmitate concentration in soybean. Crop Sci. 51:
1611-1616.
Lewis, R.S., Bowen, S.W., Keogh, M.R. and Dewey, R.E. (2010) Three nicotine demethylase
genes mediate nornicotine biosynthesis in Nicotiana tabacum L.: functional
characterization of the CYP82E10 gene. Phytochem. 71: 1988-1998.
Lewis, R.S. and Dewey, R.E. (2010) Genetics-based modification of tobacco chemistry in a
regulatory environment. Recent Adv. Tob. Sci. 36: 5-24.
Dewey, R.E. and Zhang, P. (2010) Candidate gene analysis of mutant soybean germplasm. In K.
D. Bilyeu, M.B. Ratnaparkhe, C. Kole, eds., Genetics, Genomics and Breeding of
Soybean. CRC Press, Boca Raton, FL. pp. 187-197.
Keogh, M.R., Courtney, P.D., Kinney, A.J. and Dewey, R.E. (2009) Functional characterization
of phospholipid N-methyltransferases from Arabidopsis and soybean. J. Biol. Chem. 284:
15439-15447.
Bachlava, E., Dewey, R.E., Burton, J.W. and Cardinal, A.J. (2009) Mapping candidate genes for
oleate biosynthesis and their association with the unsaturated fatty acid seed content in
soybean. Mol. Breeding 23: 337-347.
Bachlava, E., Dewey, R.E., Burton, J.W. and Cardinal, A.J. (2009) Mapping and comparison of
quantitative trait loci for oleic acid seed content in two segregating soybean populations.
Crop Sci. 49: 1-10.
Zhang, P. Burton, J.W., Upchurch, R.G., Whittle, E., Shanklin, J. and Dewey, R.E. (2008)
Mutations in a 9-stearoyl-ACP-desaturase gene are associated with enhanced stearic
acid levels in soybean seeds. Crop Sci. 48: 2305-2313.
Lewis, R.S., Jack, A.M., Morris, J.W., Robert, V.J.M., Gavilano, L., Siminszky, B., Bush, L.P.,
Hayes, A.J. and Dewey, R.E. (2008) RNAi-induced suppression of nicotine demethylase
activity reduces levels of a key carcinogen in cured tobacco leaves. Plant Biotech. J. 6:
346-354.
Chakrabarti, M., Bowen, S.W., Coleman, N.P., Meekins, K.M., Dewey, R.E. and Siminszky, B.
(2008) CYP82E4-mediated nicotine to nornicotine conversion in tobacco is regulated by
a senescence-specific signaling pathway. Plant Mol. Biol. 66: 415-427.
Bachlava, E., Dewey, R.E., Auclair, J., Wang, S., Burton, J.W. and Cardinal, A.J. (2008)
Mapping genes encoding microsomal -6 desaturase enzymes and their cosegregation
with QTL affecting oleic acid content in soybean. Crop Sci. 48: 640-650.
Cardinal, A.J., Dewey, R.E. and Burton, J.W. (2008) Estimating the individual effects of the
reduced palmitic acid fapnc and fap1 alleles on agronomic traits in two soybean
populations. Crop Sci. 48: 633-639.
Irsigler, A.S.T., Costa, M.D.L., Zhang, P., Braga, P.A., Dewey, R.E., Boston, R.S. and Fontes,
E.P.B. (2007) Expression profiling on soybean leaves reveals integration of ER- and
osmotic-stress pathways. BMC Genomics 8: 431.
Siminszky, G., Gavilano, L., Chakrabarti, M., Dewey, R.E. and Bowen, S.W. (2007) Evolution
of nicotine N-demethylase genes and their use in reducing nornicotine levels in tobacco.
Recent Adv. Tob. Sci. 33: 27-38.
Cardinal, A.J., Burton, J.W., Camacho, A.M., Yang, J.H., Wilson, R.F. and Dewey, R.E.
(2007) Molecular analysis of soybean lines with low palmitic acid content in the seed oil.
Crop Sci. 47: 304-310.
Aghoram, K., Wilson, R.F., Burton, J.W. and Dewey, R.E. (2006) A mutation in a 3-keto-acyl
ACP synthase II gene is associated with elevated palmitic acid levels in soybean seeds.
Crop Sci. 46: 2453-2459.
Siminszky, B., Gavilano, L., Bowen, S.W. and Dewey, R.E. (2005) Conversion of nicotine to
nornicotine in Nicotiana tabacum is mediated by CYP82E4, a cytochrome P450
monooxygenase. Proc. Natl. Acad. Sci. USA 102: 14919-14924.
Tang, G-Q., Novitzky, W. P., Griffin, C.H., Huber, S.C. and Dewey, R.E. (2005) Functional
characterization of two closely related soybean (Glycine max) oleate desaturase enzymes:
evidence of regulation through phosphorylation and differential stability. Plant J. 44:
433-446.
Hernández-Sebastià, C.H., Marsolais, F., Saravitz, C., Israel, D., Dewey, R.E. and Huber, S.C.
(2005) Free amino acid profiles suggest a possible role for asparagine in the control of
storage-product accumulation in developing seeds of low- and high-protein soybean
lines. J. Exp. Bot. 56: 1951-1963.
Siminszky, B. and Dewey, R.E. (2004) Developing a genomic resource for elucidating the
mechanism of nicotine to nornicotine conversion. Recent Adv. Tob. Sci. 30: 39-47.
Pantalone, V.R., Walker, D.R., Dewey, R.E. and Rajcan, I. (2004) DNA marker-assisted
selection for improvement of soybean oil concentration and quality. In R.F. Wilson, H.T.
Stalker and E.C. Brummer, eds., Legume Crop Genomics. AOCS Press, Champaign, IL.
pp. 283-311.
Siminszky, B., Freytag, A.M., Sheldon, B.S. and Dewey, R.E. (2003) P450 reductase enhances
CYP71A10-dependent phenylurea metabolism in tobacco. Pest. Biochem. Physiol. 77:
35-43.
Tang, G-Q., Hardin, S.C., Dewey, R. and Huber S.C. (2003) A novel C-terminal proteolytic
processing of cytosolic pyruvate kinase, its phosphorylation and degradation by the
proteasome in developing soybean seeds. Plant J. 34: 77–93.
Dewey, R.E. and Kinney, A.J. (2002) Phospholipid biosynthetic enzymes in plants. In J.R.
Whitaker and A.G.J. Voragen, eds., Handbook of Food Enzymology. Marcel Dekker,
New York. pp. 147–160.
Wilson, R.F., Burton, J.W., Pantalone, V.R. and Dewey, R.E. (2002) New gene
combinations governing saturated and unsaturated fatty acid composition in soybean. In
S. Kuo and H. Gardner, eds., Lipid Biotechnology. Marcel Dekker, New York. pp. 95–
113.
Wilson, R.F., Burton, J.W., Novitzky, W.P. and Dewey, R.E. (2001) Current and future
innovations in soybean (Glycine max L. Merr.) oil composition. J. Oleo Sci. 50: 353-358.
Monks, D.E., Aghoram, K. Courtney, P.D., DeWald, D. B. and Dewey, R.E. (2001)
Hyperosmotic stress induces the rapid phosphorylation of a soybean phosphatidylinositol
transfer protein homolog through activation of the protein kinases SPK1 and SPK2. Plant
Cell 13: 1205–1219.
Wilson, R.F., Marquardt, T.C., Novitzky, W.P., Burton, J.W., Wilcox, J.R., Kinney, A.J. and
Dewey, R.E. (2001) Metabolic mechanisms associated with alleles governing the 16:0
concentration of soybean oil. J. Amer. Oil Chem. Soc. 78: 335–340.
Wilson, R.F., Marquardt, T.C., Burton, J.W., Wilcox, J.R. and Dewey, R.E. (2001) Effects of
alleles governing 16:0 concentration on glycerolipid composition in developing soybeans.
J. Amer. Oil Chem. Soc. 78: 329–334.
Shank, K.J., Su, P., Brglez, I., Boss, W.F., Dewey, R.E. and Boston, R.S. (2001) Induction of
lipid metabolic enzymes during the ER stress response in plants. Plant Physiol. 126: 267277.
Siminszky, B., Sheldon, B.S., Corbin, F.T. and Dewey, R.E. (2000) A cytochrome P450
monooxygenase cDNA (CYP71A10) confers resistance to linuron in transgenic tobacco.
Weed Sci. 48: 291-295.
Pedra, J.H.F., Delu-Filho, N., Dewey, R.E., Otoni, W.C. and Fontes, E.P.B. (2000) Antisense
and sense expression of a sucrose binding protein homologue gene from soybean in
transgenic tobacco affects plant growth and carbohydrate partitioning in leaves. Plant Sci.
152: 87-98.
Goode, J.H. and Dewey, R.E. (1999) Characterization of aminoalcoholphosphotransferases from
Arabidopsis thaliana and soybean. Plant Physiol. Biochem. 37: 1-13.
Drøbak, B.K., Dewey, R.E. and Boss, W.F. (1999) Phosphoinositide-kinases and the synthesis
of polyphosphoinositides in higher plant cells. In K.W. Jeon, ed., International Review of
Cytology - A Survey of Cell Biology. Vol. 189. Academic Press, San Diego. pp. 95-130.
Siminszky, B.S., Corbin, F.T., Ward, E.R., Fleischmann, T.J. and Dewey, R.E. (1999)
Expression of a soybean cytochrome P450 monooxygenase cDNA in yeast and tobacco
enhances the metabolism of phenylurea herbicides. Proc. Natl. Acad. Sci. USA 96: 17501755.
Kearns, M.A., Monks, D.E., Fang, M., Rivas, M.P., Courtney, P.D., Chen, J., Prestwich,
G.D., Theibert, A.B., Dewey, R.E. and Bankaitis, V.A. (1998) Novel developmentally
regulated phosphoinositide binding proteins from soybean whose expression bypasses the
requirement for an essential phosphatidylinositol transfer protein in yeast. EMBO J. 17:
4004-4017.
Monks, D.E., Goode, J.H. and Dewey, R.E. (1997) Phosphatidylcholine biosynthesis in
soybeans: the cloning and characterization of genes encoding enzymes of the nucleotide
pathway. In J.P. Williams, M.U. Khan and N.W. Lem, eds., Physiology, Biochemistry
and Molecular Biology of Plant Lipids. Kluwer Academic, Dordrect, pp 110-112.
Monks, D.E., Goode, J.H. and Dewey, R.E. (1996) Characterization of soybean choline kinase
cDNAs and their expression in yeast and Escherichia coli. Plant Physiol. 110: 1197
1205.
Goode, J.H., Settlage, S.B., Wilson, R.F. and Dewey, R.E. (1995) Isolation of a calnexin
homolog from developing soybean seeds. Plant Physiol. 108: 1341.
Dewey, R.E., Wilson, R.F., Novitzky, W.P. and Goode, J.H. (1994) The AAPT1 gene of
soybean complements a cholinephosphotransferase-deficient mutant of yeast. Plant Cell
6: 1495-1507.
Dewey, R.E. and Korth, K.L. (1994) Molecular aspects of cytoplasmic male sterility in maize. In
Y.P.S. Bajaj, ed., Biotechnology in Agriculture and Forestry, Vol. 25: Maize. SpringerVerlag, Berlin, pp. 402-416.
Wilson, R.F., Kwanyuen, P., Dewey, R.E. and Settlage, S.B. (1993) Recent developments in the
molecular biochemistry and genetics of diacylglycerol acyltransferase from soybean. In
S.L. MacKenzie, D.C. Taylor eds., Seed Oils for the Future. American Oil Chemists
Society, Champaign, IL., pp. 116-135.
Hennig, J., Dewey, R.E., Cutt, J.R. and Klessig, D.F. (1993) Pathogen, salicylic acid and
developmental dependent expression of a -1,3-glucanase/GUS gene fusion in transgenic
tobacco plants. Plant J. 4: 481-490.
Dewey, R.E., Timothy, D.H. and Levings C.S. III (1991) Chimeric mitochondrial genes
expressed in the C male-sterile cytoplasm of maize. Curr. Genet. 20: 475-482.
Levings, C.S. III and Dewey, R.E. (1988) Molecular studies of cytoplasmic male sterility in
maize. Phil. Trans. R. Soc. Lond. B 319: 177-185.
Dewey, R.E., Siedow, J.N., Timothy, D.H. and Levings, C.S. III (1988) Expression of a 13 kD
maize mitochondrial protein in E. coli confers sensitivity to Bipolaris maydis toxin.
Science 239: 293-295.
Gywnn, B., Dewey, R.E., Sederoff, R.R., Timothy, D.H. and Levings, C.S. III (1987) Sequence
of the 18S-5S ribosomal gene region and the cytochrome oxidase II gene from mtDNA of
Zea diploperennis. Theor. Appl. Genet. 74: 781-788.
Stamper, S.E., Dewey, R.E., Bland, M.M., and Levings, C.S. III (1987) Characterization of the
gene urf13-T and an unidentified reading frame, ORF 25, in maize and tobacco
mitochondria. Curr. Genet. 12: 457-463.
Dewey, R.E., Hu, W.W.L. and Levings, C.S. III (1987) The urf13-T mitochondrial gene of cmsT maize. In J.L. Key and L. McIntosh, eds., Plant Gene Systems and Their Biology.
UCLA Symposia on Molecular and Cellular Biology, New Series Vol. 62. Alan R. Liss,
Inc., New York, pp. 65-74.
Dewey, R.E., Timothy, D.H. and Levings, C.S. III (1987) A mitochondrial protein associated
with cytoplasmic male sterility in the T cytoplasm of maize. Proc. Natl. Acad. Sci. USA
84: 5374-7378.
Dewey, R.E., Levings, C.S., III and Timothy, D.H. (1986) Novel recombinations in the maize
mitochondrial genome produce a unique transcriptional unit in the Texas male-sterile
cytoplasm. Cell 44, 439-449.
Dewey, R.E., Levings, C.S., III and Timothy, D.H. (1985) Nucleotide sequence of ATPase
subunit 6 gene of maize mitochondria. Plant Physiol. 79, 914-919.
Dewey, R.E., Schuster, A.M., Levings, C.S., III and Timothy, D.H. (1985) Nucleotide
sequence of F0-ATPase proteolipid (subunit 9) gene of maize mitochondria. Proc. Natl.
Acad. Sci. USA 82, 1015-1019.