Jeffery C. Young
Biology Department, Western Washington University
Bellingham, WA 98225
Education
Ph.D. Plant Biology, Ohio State University, Columbus, OH, 1994
BA Philosophy, Plant Biology Minor, Ohio State University, Columbus, OH, 1989
Appointments
Professor
Associate Professor
Assistant Professor
Postdoctoral Fellow
Western Washington University, Bellingham, WA
Western Washington University, Bellingham, WA
Western Washington University, Bellingham, WA
University of Wisconsin, Madison, Wisconsin
'10'04- '10
'99- '04
'94 -'99
Courses Taught at Western Washington University
Biology 205, Cell Biology; Biology 206, Organismal Biology; Biology 321, Genetics; Biology 322
Genetics Lab, Biology 445c/599, Introduction to Genomics , Biology 470/570, Functional Genomics,
Bio/Chem 473, Molecular Biology, Bio/Chem 475, Molecular Biology Lab
Research Focus
Our laboratory uses the model plant Arabidopsis to study transport phenomenon and pathogenesis in
plants. We employ physiological, genetic and genomic techniques.
Grants and Awards
- NSF Award #0116266 (2001-2004): Arabidopsis 2010: RUI: Genetic and Physiological
Characterization of Arabidopsis Plasma Membrane H+-ATPase Mutants, $500,000
- NSF Award #0216618 (2002): MRI/RUI: Instrumentation for Sequencing and Genomic Analysis
- Beckman Scholars Proposal (2003-2005): Recognizing Outstanding Undergraduate Students in
Chemistry and Biological Sciences Research
- NIH Award #R15GM101580 (Current) Probing the Archazolid Pharmacophore Using Plant-Based VATPase Assays, Co-PI Greg O’Neil (Chemistry), $290,251
Publications
Young, JC, Sack, FD (1992). Time-lapse analysis of gravitropism in Ceratodon protonema. American Journal of
Botany 789:(2): 1348-1358
Young, JC, Liscum, E, Hangarter, RP (1992). Spectral dependence of light-inhibited hypocotyl elongation in
photomorphic mutants of Arabidopsis: evidence for a UV-A specific photosensor. Planta 188: 106-114
Liscum, E, Young, JC, Poff, KL, Hangarter, RP (1992). Genetic separation of phototropism and blue light
inhibition of stem elongation. Plant Physiol. 100: 267-271
Zhong, H.H., Young, JC, Pease, EA, Hangarter, RP, McClung, R (1994). Interactions between light and the
circadian clock in the regulation of CAT2 expression in Arabidopsis. Plant Physiol. 104: 889-898
Young, JC and Hangarter, RP (1996) Comparative analysis of light response mutants by subtractive response
spectra. Cell and Developmental Biology.
Zagotta, M, Hicks, KA, Jacobs, CI, Young, JC, Hangarter, RP, Meeks-Wagner, DR (1996) The Arabidopsis
ELF3 gene regulates vegetative photomorphogenesis and the photoperiodic induction of flowering. Plant
Journal 10(4): 691-702
Krysan, PJ, Young, JC, Tax, F, and Sussman, MR (1996) Identification of T-DNA insertions within Arabidopsis
genes involved in signal transduction and ion transport. Proc. Natl. Acad. Sci. 93: 8145-8150
Young, JC, DeWitt, ND and Sussman, MR (1998) A Transgene Encoding a Plasma Membrane H+-ATPase that
Confers Acid Resistance in Arabidopsis thaliana Seedlings. GENETICS 149(2): 501-507
Publications with Western Washington Attribution
Publication Quality Impact Factor (average): 9.1 Citations: mean = 151, range = 10-­‐584) 1. Krysan*, PJ, Young, J* and Sussman, MR (1999) T-­‐DNA as an Insertional Mutagen in Arabidopsis. Plant Cell 11: 2283-­‐2290 *Co-­‐first author. 2. Nagpal, P, Walker, L, Young, J, Sonawala, Timpte, C, Estelle, M and Reed, J (2000) AXR2 encodes a member of the Aux/IAA protein family 1. Plant Physiol. 123, 563-­‐573 3. Gottwald, JR, Krysan , PK, Young, JC, Evert , RF and Sussman , MR (2000) Genetic evidence for the in planta role of phloem specific plasma membrane sucrose transporters. PNAS 97(25), 13979-­‐13984 4. Sussman, MR, Amasino, R, Young, JC, Krysan, PJ and Austin-­‐Phillips, S (2000) The Arabidopsis Knockout Facility at the University of Wisconsin-­‐Madison, Plant Physiol. 124(4): 1465-­‐1467 5. Young, JC, Krysan, PJ and Sussman, MR (2001) Efficient screening of Arabidopsis T-­‐DNA insertion lines. Plant Physiol. 125(2), 513-­‐518 6. Chen, JG, Ullah, H, Young, JC, Sussman, MR and Jones, AJ (2001) ABP1 is required for organized cell elongation and division in Arabidopsis embryogenesis, Genes and Development 15(7): 902-­‐911 7. Ullah, H, Young, J, Chen, JG, Kyung, HI, Sussman, M, Jones, AJ (2001) Modulation of Cell Proliferation by Heterotrimeric G-­‐protein in Arabidopsis , Science 15 (292): 2066-­‐2069 8. Krysan, PJ, Young, JC, Jester, PJ, Monson, S, Copenhaver, G, Preuss, D, and Sussman, MR (2002) Characterization of T-­‐DNA insertion sites in Arabidopsis thaliana and the implications for saturation mutagenesis, OMICS 6(2): 163-­‐174 9. Wu, Z, Liang, F, Hong, B, Young, JC, Sussman, MR, Harper, JF and Sze, H (2002) An ER-­‐bound Ca2+/Mn2+ pump, ECA1, supports plant growth and confers tolerance to Mn2+ stress, Plant Physiol. 130: 128-­‐
137 10. Monte, E, Alonso, JM, Ecker, JR, Zhang, Y, Li, X, Young, JC, and Quail, PH (2003) Isolation and characterization of phyC mutants inArabidopsis reveals complex crosstalk between phytochrome signaling pathways Plant Cell 15: 1962-­‐1980 11. Hussain D, Haydona M, Wang Y, Wonga E, Shersona S, Young J, Camakarisa J, Harper J, and Cobbetta, C (2004) P-­‐Type ATPase Heavy Metal Transporters with Roles in Essential Zinc Homeostasis in Arabidopsis. The Plant Cell 16: 1327-­‐1339 12. Robertson WR, Clark K (nee Szumlanski), Young JC, Sussman MR. (2004) An Arabidopsis thaliana Plasma Membrane Proton Pump Is Essential for Pollen Development. Genetics. 168(3):1677-­‐87 13. Baxter, IR*, Young, JC*, Armstrong, G, Fosters, N, Bogenschutz, N, Cordova T, Peer WA, Hazen SP, Murphy A, and Harper JF. (2005) A plasma membrane H+-­‐ATPase is required for the formation of proanthocyanidins in the seed coat endothelium of Arabidopsis thaliana. PNAS, 102 (7): 2649–2654 *Co-­‐first author. 14. Ellis CM, Nagpal P, Young JC, Hagen G, Guilfoyle TJ, Reed JW. (2005) AUXIN RESPONSE FACTOR1 and AUXIN RESPONSE FACTOR2 regulate senescence and floral organ abscission in Arabidopsis thaliana. Development. 132(20):4563-­‐74 15. Haruta, M, Burch, HL, Nelson, RB, Barrett-­‐Wilt, G, Kline, KG, Mohsin, SB, Young, JC, Otegui, MS, and Sussman, MR (2010) Molecular Characterization Of Mutant Arabidopsis Plants With Reduced Plasma Membrane Proton Pump Activity. Journal of Biological Chemistry, Published on March 26, 2010, doi:10.1074/jbc.M110.101733 16. Tran AB, Melly GC, Doucette R, Ashcraft B, Sebren LJ, Havko N, Young JC, O'Neil GW (2011) Synthesis and activity of the archazolid western hemisphere. Org Biomol Chem. 2011 Oct 26;(22):7671-­‐4 Other Scholarly Activity
Young, JC, Peterson, M, Nickerson, DW, Fletcher, AL, Klee, IJ, Stults, J, Pince, C, Elsaesser, K,
Trinkhaus, J, Mohl, C (2002) A gantlet of physiological conditions for testing conditional
phenotypes in Arabidopsis thaliana
- WEB Release, NSF Funded Site, 6/02 - present
-
www.gantlet.org (new)
Grant, Journal Review
Journal of Plant Growth, Plant Physiology, Plant Cell, American Journal of Botany, NSF Grant
Review
Professional Associations
American Society of Plant Biologists