Pyridine Nucleotide Regulation of Cardiac Intermediary
Metabolism
by John R. Ussher, Jagdip S. Jaswal, and Gary D. Lopaschuk
Circulation Research
Volume 111(5):628-641
August 17, 2012
Copyright © American Heart Association, Inc. All rights reserved.
Biosynthesis of NAD+/NADP+.
John R. Ussher et al. Circ Res. 2012;111:628-641
Copyright © American Heart Association, Inc. All rights reserved.
Malate-aspartate and glycerol 3-phosphate shuttles.
John R. Ussher et al. Circ Res. 2012;111:628-641
Copyright © American Heart Association, Inc. All rights reserved.
The pentose phosphate pathway (PPP).
John R. Ussher et al. Circ Res. 2012;111:628-641
Copyright © American Heart Association, Inc. All rights reserved.
Effects of ischemia on cytosolic and mitochondrial NADH. Ischemia is characterized by
diminished coronary flow and hence oxygen delivery.
John R. Ussher et al. Circ Res. 2012;111:628-641
Copyright © American Heart Association, Inc. All rights reserved.
Increased flux through the pentose phosphate pathway (PPP) in heart failure.
John R. Ussher et al. Circ Res. 2012;111:628-641
Copyright © American Heart Association, Inc. All rights reserved.