Cogmed Working Memory Training Increasing Working Memory Capacity through Computerized Training Psychoeducational Clinic NCSU www.ncsu.edu/psychology/theclinic Working memory is The ability to keep information in your mind for a short period of time (seconds) and be able to use this information in your thinking. Working memory is essential for Controlling attention Reading comprehension Mathematical reasoning Planning and organizing activities Keeping instructions in mind Resisting distraction Problem solving and fluid intelligence Signs of a poor working memory An inability of maintain attention Distractibility An inability to start projects or follow them through to completion Problems remembering instructions A habit of interrupting or not waiting for one’s turn Difficulties getting organized Learning difficulties ©2007 Cogmed Development of working memory in ADHD Test performance Visuospatial Working Memory Capacity Research hypothesis: Can working memory be improved by training? If so, does improving working memory: - affect other areas of cognition? - affect symptoms of AD(H)D? Torkel Klingberg, MD, PhD, Professor in Cognitive Neuroscience, Karolinska Institute Director – Development Cognitive Neuroscience Lab, Stockholm Brain Institute Subjects: 53 non-medicated children (9 girls, 44 boys) - Randomized to the treatment or comparison programs 7-12 years of age (mean 9.9 years) 15 ADHD predominantly inattentive 38 ADHD combined type Klingberg et al. (2005) JAACAP Intervention: computerized training of working memory Training group 5 weeks training Verbal and visuospatial working memory trials Difficulty level automatically adjusted - Matched WM span of child to each task Control group 5 weeks training Same exercises except difficulty level Remained on initial low level - Did NOT match WM span of child to task Klingberg et al. (2005) JAACAP Intervention: training procedures 40 minutes per day 5 days/week 5 weeks Weekly calls by Cogmed Personal Coach - Discuss technical difficulties - Feedback on #days of data uploaded to server The technology was later developed with the Karolinska-based company Cogmed Outcome measures: Evaluate executive functioning - Span-board task measures visuospatial WM - Digit-span measures verbal WM - Stroop interference task measures response inhibition - Raven’s Colored Progress Matrices measure nonverbal reasoning ability Evaluate ADHD symptoms -18 DSM-IV items used as a rating scale - Conners Rating Scale for parents/teachers Klingberg et al. (2005) JAACAP Research Timeline Klingberg et al. (2005) JAACAP Outcome Measure Results Treat Control Visuospatial Klingberg et al. (2005) JAACAP At follow up, the performance in the treatment group was about as high as, or higher than, at post-intervention Rating scores of ADHD symptoms (DSM-IV) Klingberg et al. (2005) JAACAP Long-term effects “How is the training effect now compared to directly after training: Has it decreased, is it unchanged or has it increased?” Of the 80% who have benefited after training: On-going research Adults with ADHD Pre-schoolers Children Aging population Gibson et al. (CHADD 2006) U.S. Independent Replication Study: Computerized Training of Working Memory Subjects Children with ADHD (100%) treated with stimulate medication prior to and during the study Ages 12-14 years Number of Subjects N = 14 Gibson et al. (CHADD 2006) U.S. Independent Replication Study: Executive Task Results Span Board Gibson et al. (CHADD 2006) Ravens U.S. Independent Replication Study: ADHD symptom ratings using DSM-IV rating scales Gibson et al. (CHADD 2006) Working memory training & school performance Subjects Children with special education needs Ages 9-12 35% with ADHD diagnosis Treatment N = 42 Working memory training in school Control N = 15 Ordinary special education activities Klingberg et al. (CHADD 2006) Working Memory Training & School Performance Klingberg et al. (CHADD 2006) Conclusion Working memory can be improved with significant improvements in: - Improved ability to sustain attention - Improved impulse control - Better complex reasoning skills - Better academic performance Klingberg et al. (2005) JAACAP In the clinical setting: Cogmed Working Memory Training The current program is designed especially for children and adolescents with attention deficits. Software-based Five weeks long Home-based Supported by Cogmed Personal Coaches TM RoboMemo software program Designed for children 7 and older Series of rotating exercises Trains the visuospatial and the verbal working memory Adaptive algorithm continually adjusts the level of difficulty - Based on the real-time performance of the user The training process 1: Interview 2: Start-up session 3: Training for 5 weeks 4: Wrap-up session 5: Follow-up Training can be started and completed with or without an office visit. How the program works The personal coach provides one-on-one support A parent or training aide supervises the child during each session The program is rigorous and engaging - 30-45 minutes each day - 5 days a week - 5 weeks A reward system provides encouragement ©2007 Cogmed What’s needed to train? PC with Internet connection Headphones or speakers Separate, quiet room preferred ©2007 Cogmed Tracking results Time line Index graph 8 out of 10 children show measurable effects Improved ability to sustain attention Improved impulse control Better complex reasoning skills Better academic performance ©2007 Cogmed New products Adults Children age 4-7 This Program was released in the fall of 2007 Currently in Development ©2007 Cogmed What they have said: Child Parent “I can focus better in school. I got all of my math homework correct.” “He has felt better within himself and does his work more quickly.” Teacher Psychologist “She is able to hold verbal information in her head better, her mental processing has improved.” “I have observed a “maturity” in each child, the ability to remember better, and be more organized.” References WM in children with diagnosed ADHD (Westerberg, Child Neuropsychology, 2004) WM training for children with ADHD, pilot results (Klingberg, J. of Clin. and Exp Neuropsychology, 2002) WM training for children with ADHD, multi-site clinical validation (Klingberg, J. Am. Ac. Child & Adol. Psychiatry, 2005) Brain imaging analysis of change following WM training (Olesen, Nature Neuroscience, 2004)
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