Session 3: Atomic Structure and Ionizing Radiation (cont’d) Lecture 3 CLRS 321 Nuclear Medicine Physics and Instrumentation 1 Lecture 2 Objectives (Adapted from your Textbook) • Describe the interactions of charged particles with matter. • Discuss the processes of excitation and ionization. • Describe the processes of photoelectric effect, Compton scattering, and pair production. • Discuss the production of characteristic X-rays. • Discuss the process that produces Auger electrons. • Write the general form of the attenuation equation for gamma photons. • Calculate the reduction of gamma radiation using the general attenuation equation. • State the relationship between the linear attenuation coefficient and the half-value layer. Interactions • Excitation – Charged particle or electromagnetic radiation supplies energy to outer shell electrons • The “excited” electron moves to a higher shell or subshell • Electron spontaneously returns to a less excited state giving up electromagnetic radiation • Ionization – Charged particle or electromagnetic radiation completely removes electron from atom • Results in an ion pair Interactions: Excitation Paul Early, D. Bruce Sodee, Principles and Practice of Nuclear Medicine, 2nd Ed., (St. Louis: Mosby 1995), pg. 13. Interactions: Ionization If an electron has a binding energy of 70 keV, then it would require 70 keV of energy to kick that electron out of its shell. . Paul Early, D. Bruce Sodee, Principles and Practice of Nuclear Medicine, 2nd Ed., (St. Louis: Mosby 1995), pg. 11. Interactions: Alpha & Beta • Alpha – Typically have energies between 3 & 8 MeV • Requires about 34 keV to strip an electron from an atom – Thus alphas can create hundreds of thousands of ion pairs in less than a mm of tissues • Beta – Can create Bremsstrahlung radiation when near high Z materials • With pure beta emitters, plastic is better shielding than lead to avoid Bremsstrahlung radiation Interactions: Photons • Represent electromagnetic radiation – Visible light • Reflected or absorbed – X-rays and gamma rays • One of three (really, maybe four) possibilities – No interaction (pass through) – Scatter (partially absorbed) – Completely absorbed » And also may become matter and thus absorbed • Rate of absorption increases exponentially with distance travelled through matter Interactions: Photoelectric Effect Total absorption of a gamma photon at the expense of an electron Photon energy must be equal or greater than electron binding energy Electron falls from outer shell and emits characteristic Xray photon Paul Christian, Donald Bernier, James Langan, Nuclear Medicine and Pet: Technology and Techniques, 5th Ed. (St. Louis: Mosby 2004) p 52. E Ebinding Ekinetic Interactions: Compton Scattering Gamma Photons don’t just disappear when they confront matter—their energy has to be accounted for Compton is a type of scatter in which an electron is ejected and the gamma photon continues at a deflected angle The amount of energy that the photon is reduced is dependent upon the angle at which it is scattered when it ejects the electron Paul Christian, Donald Bernier, James Langan, Nuclear Medicine and Pet: Technology and Techniques, 5th Ed. (St. Louis: Mosby 2004) p 53. The more the photon is deflected (greater angle), the less its energy it retains Interactions: Compton Scatter Compton events tend to increase with higher Z material The incident photon energy is equivalent to the binding energy of the electron and its kinetic energy of its recoil, plus the deflected energy of the photon The deflected energy of the photon can be calculated based on its deflected angle (θ) http://hyperphysics.phy-astr.gsu.edu/hbase/quantum/imgqua/compton2.gif ESc EO EO 1 1 cos 0.511 MeV Interactions: Compton Scatter NOTE: YOUR BOOK IS WRONG! The minimum amount of energy of a backscattered (180◦) Compton Scatter photon can be calculated as: Emin E0 2 E0 1 0.511MeV The maximum amount of backscatter energy transferred to the recoil electron in a backscatter event can be calculated as: Emax Paul Christian, Donald Bernier, James Langan, Nuclear Medicine and Pet: Technology and Techniques, 5th Ed. (St. Louis: Mosby 2004) p 53. E02 ( E0 0.2555MeV ) Interactions: Compton Scatter An example for calculating the minimum amount of energy a Tc-99m backscattered 140 keV photon can have: Emin 0.140 MeV 0.090MeV 2(0.140 MeV ) 1 0.511MeV An example for calculating the maximum energy a recoil electron can have from a maximum backscattered Tc-99m photon: (0.140MeV )2 Emax 0.049MeV (0.140MeV 0.2555MeV ) Interactions: Compton Scatter • What does all this mean??? – The minimal energy of a backscattered photon will form something called the “Backscattered peak” on the energy spectrum (we’ll cover that later). – Emin of the backscatter photon and Emax of the recoil electron is energy-dependent and the difference between the two increases with incident photon energy Interactions: Compton Scatter Radionuclide Photon E Emin of Backscattered Photon Emax of Recoil Electron I-125 27.5 keV 24.8 keV 3.3 keV Xe-133 81 keV 62 keV 19 keV Tc-99m 140 keV 91 keV 49 keV I-131 364 keV 150 keV 214 keV Annihilation 511 keV 170 keV 341 keV Co-60 1330 keV 214 keV 1116 keV -- To infinity 255.5 To infinity Since the energy imparted to the recoil electron must exceed the binding energy of the electron, this means that Compton Scatter is more likely to occur at higher incident photon energies (to a point—we will soon see). From Table 6-2, p. 78, Physics in Nuclear Medicine, 3rd Ed., by Simon Cherry, James Sorenson, and Michael Phelps, Saunders: Philadelphia, 2003. Interactions: Pair Production Requires gamma photon of at least 1.022 MeV to pass near a highelectrical field of a nucleus Energy is converted to matter (m=E/c2) A positron and electron are created, each with a mass equivalent of 511keV Paul Christian, Donald Bernier, James Langan, Nuclear Medicine and Pet: Technology and Techniques, 5th Ed. (St. Louis: Mosby 2004) p 53. Extra Nuclear Release: Bremsstrahlung Important consideration when using beta emitters German for “breaking radiation” Beta decelerating in vicinity of high density (high Z) nucleus dissipates energy in the form of x-ray photons Best to use plastic or lucite syringe shields with beta emitters to avoid the Bremsstrahlung effect as the beta particles penetrate lead shielding Paul Christian, Donald Bernier, James Langan, Nuclear Medicine and Pet: Technology and Techniques, 5th Ed. (St. Louis: Mosby 2004) p 54. Can get poor quality nuclear medicine images using Bremsstrahlung (ex: Sr-89) Extra Nuclear Release: (Energy States of Electrons) This picture from the Sodee text represents the electron energy states as different speed limits around the nucleus of an atom. In order for a car at 70 mph to go down to the 65 mph speed limit, it must lose a “quantum” of 5 mph. For electrons, this quantum is in the form of a specific wavelength of electromagnetic radiation. Paul Early, D. Bruce Sodee, Principles and Practice of Nuclear Medicine, 2nd Ed., (St. Louis: Mosby 1995), pg. 11. Extra Nuclear Release: Characteristic X-rays Paul Christian, Donald Bernier, James Langan, Nuclear Medicine and Pet: Technology and Techniques, 5th Ed. (St. Louis: Mosby 2004) p 54. This figure from your textbook shows what happens when an electron loses energy to move from the L shell to the K shell. Again Electromagnetic radiation is emitted, but it is of a higher energy (shorter wavelength/higher frequency) than visible light and is in the form of an X-ray photon. Such an emission is called a “characteristic X-ray” and its “character” is dependent upon and equal to the specific difference in energy states between the L and K shells of the atom. Extra Nuclear Release: Auger Electrons Paul Christian & Kristen M. Waterstram-Rich, Nuclear Medicine and Pet/CT: Technology and Techniques, 6th Ed. (St. Louis: Mosby 2004), Fig 2-25, p 57. Attenuation and Transmission of Photons This is how all the gamma radiation eventually succumbs to matter It is absorbed or attenuated. This is how it relates to instrumentation Paul Christian, Donald Bernier, James Langan, Nuclear Medicine and Pet: Technology and Techniques, 5th Ed. (St. Louis: Mosby 2004) p 52. Attenuation and Transmission of Photons • Attenuation Combined effects of attenuation is expressed by the linear attenuation coefficient (μ), which is in the units 1/distance(cm-1). The attenuation of incident radiation (I) can be expressed as follows: Paul Christian, Donald Bernier, James Langan, Nuclear Medicine and Pet: Technology and Techniques, 5th Ed. (St. Louis: Mosby 2004) p 52. X is the distance through which the incident radiation travels through the attenuating material. Paul Christian & Kristen M. Waterstram-Rich, Nuclear Medicine and Pet/CT: Technology and Techniques, 6th Ed. (St. Louis: Mosby 2004), p 57. Attenuation and Transmission of Photons • Half-Value Layer (HVL) – Similar concept to T1/2 – Layer of attenuating material that will absorb ½ the incident radiation – Specific for type of material and energy of incident radiation – Is related to μ according to the following: Paul Christian & Kristen M. Waterstram-Rich, Nuclear Medicine and Pet/CT: Technology and Techniques, 6th Ed. (St. Louis: Mosby 2004), p 57. Where have we seen this before??? Attenuation and Transmission of Photons • Substituting the previous for μ, our attenuation equation now looks like… Paul Christian & Kristen M. Waterstram-Rich, Nuclear Medicine and Pet/CT: Technology and Techniques, 6th Ed. (St. Louis: Mosby 2004), p 57. Attenuation and Transmission of Photons • An example (from book) – I-131 • (364 keV principle gamma photon E) – Lead is the shielding • HVL is 0.3 cm for 364 keV photons • Thickness of the lead is 0.9cm – Incident radiation field is 5mR/hr 0.693 2.31cm 1 0.3cm Paul Christian & Kristen M. Waterstram-Rich, Nuclear Medicine and Pet/CT: Technology and Techniques, 6th Ed. (St. Louis: Mosby 2004), p 57. Attenuation and Transmission of Photons • Mass Attenuation Coefficient – Based on material density • Is related to the linear attenuation coefficient – Physicists can break this down so that they can measure attenuation according to Compton scatter, photoelectric effect, and pair production Paul Christian & Kristen M. Waterstram-Rich, Nuclear Medicine and Pet/CT: Technology and Techniques, 6th Ed. (St. Louis: Mosby 2004), p 57. Next time: Basic Electrical Concepts http://www.waltsense.com/storage/articl es/20090429_finger-insocket.jpg?__SQUARESPACE_CACH EVERSION=1241027409629
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