Advancing the Science Webinar Series:
Chemical-Induced Asthma
The Role of Toxicology in Asthma Hazard Assessment
This webinar series will discuss the
advances being made with chemicalinduced asthma and the role of clinical,
toxicological, and epidemiological
research in regulatory and hazard
characterization approaches. Future
topics will include:



Environmental contributions to
asthma prevalence: assessing the
link between exposure and
disease (June 2016)
Asthma risk assessment: A
regulatory perspective (August
2016)
Asthma-specific hazard
characterization approaches: A
novel approach to a complex
problem (October 2016)
FREE Webinar, Registration is
REQUIRED.
Register for the webinar at:
aciscience.org/asthma
Certificate of Completion for 5 Continuing
Education hours available for attending all
5 webinars and completing the surveys.
April 28th, 2016
2:00PM EST
A review of the in vivo, in vitro, and in silico
models used for toxicological assessments of
asthma and surrogate or related endpoints,
specifically their utility and limitations. This
speaker will also discuss new methods, tests,
and approaches for toxicological assessment.
Dr. David Basketter
Learning Objectives:
 To discuss in vivo, in vitro, and in silico models for testing asthma and
surrogate or related endpoints
 To discuss the types of reliable, human relevant information that these
models provide
 To discuss the limitations of these models when considering their use
for human health hazard assessment
Dr. David Basketter is a Eurotox Registered Toxicologist and a Fellow of the Royal
Institute of Biology, the Royal College of Pathology, the British Toxicology Society,
the Royal Society of Medicine, and the Academy of Toxicological Sciences. He
previously worked at the Unilever Safety Laboratory on allergy and irritation and is
the past President of the European Society of Contact Dermatitis. He is the chair of
committees on irritation and allergy topics, including European trade associations
for cosmetics and cleaning products, at the European Center for the Validation of
Alternative Methods (ECVAM) Scientific Advisory Committee (ESAC) and at the
Japanese Centre for Validation of Alternative Methods. He is the co-developer of
the local lymph node assay (LLNA). Current research interests include development
of non-animal methods for the identification and assessment of irritants and
allergens.
Sponsored by the American Cleaning Institute (ACI), in collaboration with the Toxicology
Excellence for Risk Assessment (TERA) Center, University of Cincinnati and Endorsed by the
Society of Toxicology and Society for Risk Analysis
Society of Risk Analysis