Genes that were included in the rabbit gene chip GenBank ID Gene Name DQ529234 NM_001082135 AY005131 AB021298 EF472882 EF472883 EF472884 EF472885 EF472886 EF472887 EF397306 D82875 AB042195 AB021296 AB021297 J03462 B-cell CLL/lymphoma 2 protein (Bcl-2) BCL2-like 1 (BCL2L1), nuclear gene encoding mitochondrial protein Bcl-X B-type Fas antigen Caspase 1 Caspase 11 Caspase 14 Caspase 2 Caspase 7 Caspase 9 Caspase 10 Deoxyribonuclease I DRAK1 Fas antigen Fas antigen spliced variant Fast skeletal muscle troponin C Apoptosis 1. 2. 3. 4. 5. 6. 7. 8. 9. 10. 11. 12. 13. 14. 15. 16. Blood coagulation cascade 17. 18. 19. 20. 21. 22. L12139 U77477 AF003200 AF395821 S73493 AF080065 Alpha-1-antitrypsin Factor VII Factor X Factor XI Heparin cofactor II=plasma thrombin inhibitor Prothrombin precursor 23. 24. 25. 26. 27. M81396 AY138902 NM_001082291 NM_001101714 S61902 Thrombin Thrombomodulin precursor Tissue factor Tissue factor pathway inhibitor (lipoprotein-associated coagulation inhibitor) Tissue factor pathway inhibitor=Kunitz-type protease inhibitor Cell adhesion 28. 29. 30. 31. 32. 33. 34. 35. 36. 37. 38. 39. 40. 41. 42. 43. 44. 45. 46. 47. X62075 U82750 U82751 EF472915 NM_001082677 EF472878 S80206 M55442 S77513 AY195896 AF184591 M73781 DQ356265 U28945 S82979 U26535 D16544 U39446 AF454919 AY212510 Cell cycle control Alpha-actinin ADAM 6d ADAM 6e ADAM 10 ADAM 2 ADAM 9 Fibronectin Fomesticus vitronectin Integrin alpha 5 Integrin beta 1 Integrin beta3 Integrin beta 8 subunit Kit ligand Ksp-cadherin Laminin beta 2 subunit L-selectin precursor Osteopontin P-selectin Thrombospondin 2-like protein Vascular cell adhesion molecule (VCAM-1) 48. 49. 50. 51. 52. 53. 54. 55. 56. 57. 58. 59. 60. 61. 62. U24656 AF012745 AF510726 AF041421 AF042497 AF412307 AF413111 D14906 D14905 AF495878 NM_001081999 NM_001082756 X90592 AB010995 U16821 Annexin I Annexin VIII Annexin XIIIb Bone morphogenetic protein 2 Bone morphogenetic protein 4 Bone morphogenetic protein 5 Bone morphogenetic protein 7 Calmodulin-dependent protein kinase II-delta Calmodulin-dependent protein kinase II-gamma 2 Caveolin Cyclin-dependent kinase-like 2 (CDC2-related kinase) p21-activated protein kinase I (PAKI) p53 protein p97 protein Particle major protein p50 Cell signaling 63. 64. 65. 66. 67. 68. AF089893 AF089895 AF274319 AF076969 NM_001082746 NM_001082655 69. 70. 71. 72. 73. X75345 Z30163 AF247647 AF333177 AF333178 cAMP-dependent protein kinase subunit R1 alpha cAMP-dependent protein kinase subunit R2 beta cGMP-dependent protein kinase II (cGK-II) cGMP-dependent protein kinase type 1 alpha Heme-regulated eIF-2a kinase Inhibitor of kappa light polypeptide gene enhancer in B-cells, kinase complexassociated protein (IKBKAP) MAP kinase activated protein kinase 2 MAP kinase kinase 1 Osteonectin Receptor tyrosine kinase ErbB1 Receptor tyrosine kinase ErbB2 74. 75. 76. 77. 78. 79. 80. 81. AF333179 AF333180 AF136242 U42424 AB073102 AF323272 AF139639 DQ356266 Receptor tyrosine kinase ErbB3 Receptor tyrosine kinase ErbB4 Retinoic acid receptor RXR alpha Rho-associated-ser/thr kinase ryk mRNA for tyrosine kinase-related protein Secreted frizzled-related protein 2 Serum and glucocorticoid-regulated protein kinase (Sgk) Transmembrane tyrosine kinase receptor (c-kit) Chemokines/Cytokines/Inflammation/ Immune response 82. 83. 84. 85. 86. 87. 88. 89. 90. 91. 92. 93. 94. 95. 96. 97. 98. 99. NM_001082195 NM_001089311 NM_001089312 NM_001082207 M96942 D21835 D21832 AF169170 AF169176 AF068058 AF068057 L24445 EF112476 M28161 M57440 M57439 AF123437 M12845 CD14 molecule CD1a molecule CD1b molecule CD28 molecule Class II (HLA-DOB gene homologue) Interleukin 1 beta Interleukin 1 receptor antagonist Interleukin 4 variant IL-4delta 2 Interleukin 6 Interleukin 10 Interleukin 2 Interleukin 8 receptor subtype B Lefty MHC class II RLA-DR-alpha Monocyte chemoattractant protein-1 (MCP 1) Neutrophil attractant/activation protein-1 (NAP 1) Neutrophil-activating peptide 78 (ENA 78) Tumor necrosis factor (TNF) Growth factors and related molecules 100. 101. 102. 103. 104. 105. 106. 107. 108. 109. 110. 111. 112. 113. 114. 115. 116. 117. 118. 119. 120. 121. 122. 123. 124. 125. 126. AB217855 AF333181 AH012916 AF474181 AF013269 L12034 AF184968 AF020291 U06470 U12310 NM_001082342 NM_001082636 AF333182 U75390 AF022961 AB010386 AF049241 AY553907 AY421758 U82163 AF487889 AY347260 AB020215 X04793 X04795 M19338 X04796 Connective tissue growth factor Epidermal growth factor Fibroblast growth factor 5 (FGF 5) Fibroblast growth factor 8b (FGF 8) Fibroblast growth factor 9 Fibroblast growth factor mRNA Fibroblast growth factor receptor 2 (FGFR 2) Fibromodulin Galectin 3 Gro homolog GRO protein (GRO) Growth hormone receptor (GHR) Heparin-binding epidermal growth factor Insulin-like growth factor 1 precursor (IGF 1) Insulin-like growth factor IB (IGF IB) Interferon gamma Keratinocyte growth factor (KGF) Midkine Neuregulin 1 alpha isoform Oncogene rsc Osteoglycin Platelet derived growth factor D Platelet-derived growth factor beta Protein kinase C alpha Protein kinase C beta Protein kinase C delta Protein kinase C gamma 127. 128. 129. 130. 131. 132. 133. 134. 135. 136. 137. 138. 139. 140. U78768 M20014 AF243516 M86381 M25664 DQ013342 AF333183 AF000133 U66205 AY429466 AY196796 DQ221768 AF453570 AB017155 Protein kinase c zeta Protein kinase C-n Putative epidermal growth factor receptor Serum and growth factor-inducible gene Ps4e Synovial cell activator Thrombopoietin receptor Transforming growth factor alpha Transforming growth factor beta 1 Transforming growth factor induced protein Transforming growth factor-beta 2 Vascular endothelial growth factor (VEGF) Vascular endothelial growth factor receptor 1 Vascular endothelial growth factor receptor 3 VEGF receptor-2/Flk-1 Metabolism/ Enzymes/Others 141. 142. 143. 144. 145. 146. 147. 148. 149. 150. 151. 152. 153. J05041 L23202 M12046 AF541960 AF541961 D10883 NM_001082239 M91004 AF245469 AY421757 AF311974 X59931 AY159324 Angiotensin converting enzyme Angiotensin-converting isozyme Atrial natriuretic polypeptides Calcineurin A alpha Calcineurin A beta Calcyclin-associated protein (CAP 50) Creatine kinase, muscle (CKM) Endothelial leukocyte adhesion molecule I Endothelin B receptor Endothelin converting enzyme Endothelin receptor type A Endothelin 1 FK506 binding protein 12.6 154. 155. 156. 157. 158. 159. 160. 161. 162. 163. 164. 165. 166. NM_001082027 AF202899 AF339158 AF404277 Z49747 M64656 M64657 NM_001082118 NM_001082698 NM_001082303 Y00701 M17250 NM_001082240 H+,K+-ATPase alpha 2c subunit Heat shock protein 47 Mannose-6-phosphate/insulin-like growth factor II receptor Phosphatidic acid phosphatase type 2A Phospholipase C Phosphorylase kinase alpha subunit Phosphorylase kinase beta subunit Potassium voltage-gated channel, Shal-related subfamily, member 2 (KCND2) Protein phosphatase 1A (formerly 2C), magnesium-dependent, alpha isoform Protein phosphatase regulatory subunit (RG1) Protein phosphatase-1 catalytic subunit Tryptophan hydroxylase UDP-glucuronosyltransferase Oxidative stress/ Oxidoreducatases 167. 168. 169. 170. 171. 172. 173. 174. 175. 176. 177. 178. 179. 180. Z97654 NM_001082282 M96556 X69799 AJ002388 Y15406 L12405 NM_001082681 NM_001082388 AF332576 L10912 AB008784 M19917 M36538 12-Lipoxygenase 15-Lipoxygenase 5-Lipoxygenase-activating protein Alcohol dehydrogenase, class I Alcohol dehydrogenase, isozyme 1 Alcohol dehydrogenase, class III Copper/zinc-superoxide dismutase Cyclooxygenase-1 (COX-1) Cyclooxygenase-2 (COX-2) Cytochrome P-4B1 isoform Cytochrome P-450 2B-Bx Cytochrome P450 2D/I Cytochrome P-450 isozyme 6 Cytochrome P-450 LM4 181. 182. 183. 184. 185. 186. 187. 188. 189. 190. 191. 192. 193. 194. 195. 196. 197. 198. 199. 200. Z67878 NM_001082285 NM_001082246 NM_001082784 NM_001082284 NM_001082245 AY340972 X13837 L23766 AY421756 S61699 AB016237 L28808 AJ012536 E01314 U91584 AY179960 U85094 AF200350 BR000301 Extracellular superoxide dismutase Flavin containing monooxygenase 1 (FMO1) Flavin containing monooxygenase 3 (FMO3) Flavin containing monooxygenase 4 (FMO4) Flavin containing monooxygenase 4 (FMO4) Flavin containing monooxygenase 5 (FMO5) Forkhead transcription factor L2 (FoxL2) Glutathione peroxidase Glutathione S-transferase Heme oxygenase 1 Heme oxygenase 2 LOX-1 mRNA for lectin-like oxidized LDL receptor Manganese superoxide dismutase NADH-ubiquinone oxidoreductase chain 2 NADPH-cytochrome P450 reductase Nitric oxide synthase, constitutive Nitric oxide synthase, endothelial (NOS3) Nitric oxide synthase, inducible (NOS2) Nitric oxide synthase, neuronal (NOS1) NOX5 mRNA for predicted NADPH oxidase 5 Proteases and their inhibitors 201. 202. 203. 204. 205. 206. 207. M13364 M13363 NM_001082059 AF148956 NM_001082264 M16476 EF472888 Calcium-dependent protease Calcium-dependent protease large subunit mu-type Calpain 3, p94 Calpain L, p82 Calpain, small subunit 1 Calpastatin Cathepsin B 208. 209. 210. 211. 212. 213. 214. 215. 216. 217. 218. 219. EF472890 AF458078 AF506008 AF346415 U46069 EF472908 L08418 AF020710 AF074325 AF097708 AY029518 AY453856 Cathepsin D Cathepsin L Cysteine protease CPP32 Eppin Fertilin alpha subunit Plasminogen activator inhibitor 2 Procathepsin E Protein inhibitor of neuronal nitric oxide synthase (PIN) Putative plasminogen activator inhibitor-1 Serine protease (HTRA) Tissue-type plasminogen activator Urokinase plasminogen activator (uPA) Receptors 220. 221. 222. 223. 224. 225. 226. 227. 228. L01700 AF145438 AF451328 NM_001082683 D49842 NM_001082208 M58021 AY275542 AF182217 Adenosine receptor A1 Adenosine receptor A3 Angiotensin receptor 2 CD38 molecule CD86 CD86 molecule IL-8 receptor Metabotropic glutamate receptor 6 Pregnane x receptor (NR1I2) Structural molecules 229. 230. 231. 232. S83371 D49399 D83228 L01477 Collagen, pro alpha 1 type III Collagen, type I alpha 2 Collagen, type II Collagen, type IV 233. 234. 235. 236. 237. 238. 239. 240. 241. 242. 243. 244. 245. 246. 247. L47283 AF451331 J05042 AF247705 S78179 M17820 F059201 AF056312 AF170528 AF170529 AB004812 U32574 M21983 M76233 X64696 Collagen, type IV alpha 3 Collagen, type V alpha 1 Collagen, type VIII alpha-1 Collagen, type X alpha 1 Collagen, type XII Collagenase-1 precursor (MMP-1) Collagenase-3 precursor Coronin Glycoprotein IIb (GPIIb) Glycoprotein IIIa (GPIIIa) Large aggregating cartilage proteoglycan core protein Myosin heavy chain (MHC) Myosin light chain 2 Smooth muscle myosin light chain kinase Titin Transcription factors 248. 249. 250. 251. 252. 253. 254. 255. 256. 257. 258. 259. AJ291306 AJ291307 AJ291320 AF035178 U09823 X74728 U47663 X68142 AF404275 AF404276 AY273790 AJ291311 c-jun transcription factor (c-jun gene) c-myc transcription factor (c-myc gene) Early growth response 1 zinc-finger transcription factor (egr-1 gene) Elongation factor 1 A2 (EEF1A-2) Elongation factor 1 alpha (Rabefla2) Elongation factor 1 beta Elongation factor 1 delta (Rabef1D) Elongation factor 1 gamma Endothelial differentiation gene 1 Endothelial differentiation gene 7 Hypoxia inducible factor 1 alpha Nuclear factor of activated T-cells (nfatx gene) 260. 261. 262. 263. AY166781 U66564 AF003894 AF003895 Peroxisome proliferator-activated receptor gamma 3 (PPAR gamma 3) RUSH-1 alpha Upstream stimulatory factor 1a Upstream stimulatory factor 1b Transporter/Carrier molecules 264. 265. 266. 267. 268. 269. 270. 271. 272. 273. 274. 275. 276. 277. AF407578 NM_001082389 X06659 U10695 U39356 L42979 M36603 AF118852 AY339876 AF372520 NM_001082260 NM_001082063 X68071 U18344 Acyl CoA binding protein Alpha-hemoglobin Apolipoprotein A-I Apolipoprotein B mRNA editing protein Apolipoprotein C-IV Apolipoprotein D (apoD) Apolipoprotein E Apolipoprotein J/clusterin Glucose transporter type 4 (GLUT4) Haptoglobin Hemoglobin, beta Hyperpolarization-activated cyclic nucleotide-gated channel 1 Ras-related protein (Rab2) Serum albumin precursor Vascular remodeling 278. 279. S76584 J04712 280. 281. 282. 283. EF472901 EF472902 AB006779 D63579 Decorin=proteoglycan Hyperoxia induced (HI) 1 gene encoding a tissue inhibitor of metal proteinases (TIMP) Matrix metalloproteinase 10 Matrix metalloproteinase 11 Matrix metalloproteinase 12 Matrix metalloproteinase 2 284. 285. 286. 287. 288. 289. 290. 291. 292. 293. 294. D26514 U73940 U83918 EF472903 EF472904 EF472905 EF472906 R86534 AF069713 AF069714 AF069715 Matrix metalloproteinase 9 Membane-type 1 metalloproteinase precursor (MMP 14) Membrane-type 1 metalloproteinase Membrane-type 2 matrix metalloproteinase Membrane-type 3 matrix metalloproteinase Membrane-type 4 matrix metalloproteinase Membrane-type 5 matrix metalloproteinase Metallo-elastase Tissue inhibitor of metalloproteinase-2 (TIMP 2) Tissue inhibitor of metalloproteinase-3 (TIMP 3) Tissue inhibitor of metalloproteinase-4 (TIMP 4)
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