EBMT ABSTRACTS SUBMITTED TO ASH 2014 1. Similar Outcome of Upfront Unrelated and Matched Sibling Donor Hematopoietic Stem Cell Transplantation in Idiopathic Aplastic Anaemia of Childhood and Adolescence: A Cohort Controlled Study on Behalf of the UK Paediatric BMT WP, of the PD WP and of the SAA WP of the EBMT Result Type: Paper Number: 256 Presenter: Carlo Dufour Program: Oral and Poster Abstracts Session: 508. Bone Marrow Failure: Molecular Mechanisms: Diagnosis and Treatment Time and Location: Monday, December 8, 2014: 7:00 AM-8:30 AM West Building, 3005-3007 (Moscone Center) 2. Allogeneic Hematopoietic Stem-Cell Transplantation (HSCT) in First Complete Remission Is Superior Compared to Chemotherapy/Autologous HSCT in Patients with Intermediate-Risk Cytogenetics Acute Myeloid Leukemia Lacking Mutations in NPM1, FLT3-ITD, and CEBPA: A Joint Study of AMLSG, Cetlam and Acute Leukemia Working Party of EBMT Result Type: Paper Number: 324 Presenter: Jordi Esteve Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Comparative Transplantation Outcomes Time and Location: Monday, December 8, 2014: 7:00 AM-8:30 AM South Building, Esplanade 304-306-308 (Moscone Center) 3. Long-Term Follow-up Data Support the Curative Potential of Allogeneic Hematopoietic Cell Transplantation in Patients with Chronic Lymphocytic Leukemia: A Retrospective Analysis from the Chronic Malignancies Working Party of the EBMT Result Type: Paper Number: 2561 Presenter: Michel Van Gelder Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 1 4. Reduced Intensity Vs. Standard Conditioning Followed By Allogeneic Stem Cell Transplantation for Patients with MDS or Secondary AML: A Prospective, Randomized Phase III Study of the Chronic Malignancies Working Party of the EBMT (RICMAC-Trial) Result Type: Paper Number: 320 Presenter: Nicolaus Kröger Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Comparative Transplantation Outcomes Time and Location: Monday, December 8, 2014: 7:00 AM-8:30 AM South Building, Esplanade 304-306-308 (Moscone Center) 5. Haplotransplants Versus Other Alternative Donors for Allogeneic Stem Cell Transplantation in Non Hodgkin Lymphoma (NHL): A Retrospective Analysis of the EBMT Lymphoma Working Party Result Type: Paper Number: 2573 Presenter: Sascha Dietrich Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 6. Allogeneic Hematopoietic Stem Cell Transplantation in Myelodysplastic Syndrome (MDS) Patients at Lower Risk According to International Prognostic Scoring System (IPSS) : A Retrospective Study on Behalf of the Cmwp of the EBMT Result Type: Paper Number: 2530 Presenter: Marie Robin Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 7. Allogeneic Hematopoietic Stem Cell Transplantation for Multiple Myeloma: Evolution and Outcomes over More Than Two Decades within EBMT Centers Result Type: Paper Number: 2554 Presenter: Mauricette Michallet Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 2 8. Influence of Preexisting Invasive Aspergillosis on Allo-HSCT Outcome: A Retrospective EBMT Analysis from the Infectious Diseases and Acute Leukemia Working Parties Result Type: Paper Number: 185 Presenter: Olaf Penack Program: Oral and Poster Abstracts Session: 721. Clinical Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Transplant Toxicities: Infections in Transplant Recipients Time and Location: Sunday, December 7, 2014: 4:30 PM-6:00 PM West Building, 2009-2011-2022-2024 (Moscone Center) 9. Allogeneic Hematopoietic Cell Transplantation in AML with Normal Karyotype and NPM1 Mutated FLT3-ITD Negative: A Retrospective Analysis from the Acute Leukemia Working Party of EBMT Result Type: Paper Number: 1230 Presenter: Ali Bazarbachi Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster I Time and Location: Saturday, December 6, 2014: 5:30 PM-7:30 PM North Building, Hall E (Moscone Center) 10. Allogeneic Stem Cell Transplantation in Myelodysplastic Syndrome; A More Favorable Outcome after Fludarabine and Treosulfan Conditioning. a Survey on Behalf of the Chronic Malignancies Working Party of the EBMT Result Type: Paper Number: 1216 Presenter: Avichai Shimoni Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster I Time and Location: Saturday, December 6, 2014: 5:30 PM-7:30 PM North Building, Hall E (Moscone Center) 11. Impact of CD3+ and CD34+ Doses in the Mobilized Peripheral Blood Stem Cell Grafts on the Outcome of Reduced-Intensity Conditioning Allogenic Transplantation from Matched Unrelated Donors for Acute Myeloid Leukemia – an Analysis from the Acute Leukemia Working Party of the EBMT Result Type: Paper Number: 190 Presenter: Tomasz Czerw Program: Oral and Poster Abstracts Session: 722. Clinical Allogeneic Transplantation: Acute and Chronic GVHD, Immune Reconstitution: Risk Factors for GVHD and Outcomes Time and Location: Sunday, December 7, 2014: 4:30 PM-6:00 PM West Building, 3009-3011-3022-3024 (Moscone Center) 3 12. Allogeneic HCT in Patients with 17p-CLL: Results of a Non-Interventional Study of the EBMT & Eric Result Type: Paper Number: 1224 Presenter: Johannes Schetelig Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster I Time and Location: Saturday, December 6, 2014: 5:30 PM-7:30 PM North Building, Hall E (Moscone Center) 13. Does Ex Vivo CD34+ Cell Selection Change the Outcome of Systemic Sclerosis Patients Treated with Autologous Hematopoietic Stem Cell Transplantation (AHSCT), an Adwp EBMT Study? Result Type: Paper Number: 2517 Presenter: Maria Oliveira Program: Oral and Poster Abstracts Session: 731. Clinical Autologous Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 14. Contrasting Factors Determine the Kinetics of Disease Relapse after Allogeneic Stem Cell Transplantation (allo-SCT) for Acute Myeloid Leukaemia (AML): a Survey from the Acute Leukaemia Working Party of the EBMT Result Type: Paper Number: 3945 Presenter: Charles Craddock Program: Oral and Poster Abstracts Session: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence: Poster III Time and Location: Monday, December 8, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 15. Allogeneic HCT with Reduced Intensity Conditioning Versus Autologous HCT for >55 Years Old Patients with Acute Lymphoblastic Leukemia in First Complete Remission: An Analysis from Acute Leukemia Working Party of the EBMT Result Type: Paper Number: 3974 Presenter: Sebastian Giebel Program: Oral and Poster Abstracts Session: 731. Clinical Autologous Transplantation: Results: Poster III Time and Location: Monday, December 8, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 4 16. Autologous Stem Cell Transplantation (ASCT) for the Treatment of Patients with Waldenstrom’s Macroglobulinemia / Lymphoplasmacytic Lymphoma (WM/LPL). a Risk Factor Analysis By the European Society for Blood and Marrow Transplantation (EBMT) Lymphoma Working Party Result Type: Paper Number: 678 Presenter: Charalampia Kyriakou Program: Oral and Poster Abstracts Session: 731. Clinical Autologous Transplantation: Results: Clinical Results in Lymphoid Malignancies Time and Location: Monday, December 8, 2014: 4:30 PM-6:00 PM West Building, 3001-3003-3014-3016 (Moscone Center) 17. Activity and Tolerability of Azacitidine in Patients Who Relapse after Allogeneic Stem Cell Transplantation (allo-SCT) for Acute Myeloid Leukemia (AML) and Myelodysplasia (MDS): a Survey from the European Society for Blood and Marrow Transplantation (EBMT Result Type: Paper Number: 2506 Presenter: Charles Craddock Program: Oral and Poster Abstracts Session: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 18. Higher Doses of Antithymocyte Globulin (ATG) Increase the Risk of Relapse in Acute Myeloid Leukemia (AML) Patients Undergoing Matched Related Donor Allogeneic Transplantation in First Complete Remission (CR1): An Analysis from the Acute Leukemia Working Party of EBMT Result Type: Paper Number: 729 Presenter: Raynier Devillier Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Improving Transplantation Outcomes Time and Location: Monday, December 8, 2014: 6:15 PM-7:45 PM South Building, Esplanade 304-306-308 (Moscone Center) 19. Matched and Mismatched Unrelated Donor Versus Unmanipulated Haploidentical Donors for Hematopoietic Cell Transplantation in Acute Leukemia in Remission: A Pair Matched Analysis on Behalf of the Acute Leukemia Working Party (ALWP) of the European Society for Blood and Marrow Transplantation (EBMT) Result Type: Paper Number: 1219 Presenter: Simona Piemontese Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster I 5 Time and Location: Saturday, December 6, 2014: 5:30 PM-7:30 PM North Building, Hall E (Moscone Center) 20. Autologous Stem Cell Transplantation for Primary Mediastinal B Cell Lymphoma in the Rituximab Era: A Retrospective Study By the EBMT Lymphoma Working Party Result Type: Paper Number: 1195 Presenter: Irit Avivi Program: Oral and Poster Abstracts Session: 731. Clinical Autologous Transplantation: Results: Poster I Time and Location: Saturday, December 6, 2014: 5:30 PM-7:30 PM North Building, Hall E (Moscone Center) 21. Prediction of Allogeneic HSCT Related Mortality in Acute Leukemia: Exploring Boundaries of Prediction through Machine Learning Based Modeling. a Data Mining Study from the Acute Leukemia Working Party (ALWP) of the EBMT Result Type: Paper Number: 2568 Presenter: Roni Shouval Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 22. RIC Allo-SCT with Flu/Bu in Comparison to Flu/Mel for AML Results in Similar Overall Survival: A Report from the ALWP of the EBMT Result Type: Paper Number: 545 Presenter: Frederic Baron Program: Oral and Poster Abstracts Session: 721. Clinical Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Transplant Toxicities: Novel Conditioning Regimens Time and Location: Monday, December 8, 2014: 2:45 PM-4:15 PM West Building, 2006-2008 (Moscone Center) 23. Haploidentical Versus Autologous Stem Cell Transplantation in Adult Acute Leukemia: A Matched Pair Analysis from the Acute Leukemia Working Party of the European Society for Blood and Marrow Transplantation (EBMT) Result Type: Paper Number: 2508 Presenter: Norbert Gorin Program: Oral and Poster Abstracts Session: 723. Clinical Allogeneic and Autologous Transplantation: Late Complications and Approaches to Disease Recurrence: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM 6 North Building, Hall E (Moscone Center) 24. Double Cord Blood Transplantation: Incidence, Organ Involvement and Risk Factors of Acute Graft Versus Host Disease. a Retrospective Analysis on Behalf of Eurocord, ALWP and Cqwp-EBMT Result Type: Paper Number: 187 Presenter: Erick Xavier Program: Oral and Poster Abstracts Session: 722. Clinical Allogeneic Transplantation: Acute and Chronic GVHD, Immune Reconstitution: Risk Factors for GVHD and Outcomes Time and Location: Sunday, December 7, 2014: 4:30 PM-6:00 PM West Building, 3009-3011-3022-3024 (Moscone Center) 25. High Dose Therapy and Autologous Stem Cell Transplantation in Marginal Zone Lymphoma : An EBMT-FIL-Gimeto Retrospective Study Result Type: Paper Number: 2526 Presenter: Irit Avivi Program: Oral and Poster Abstracts Session: 731. Clinical Autologous Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 26. Outcomes of Cord Blood Transplantation Using Reduced Intensity Conditioning for Chronic Lymphocytic Leukemia: A Retrospective Study on Behalf of Eurocord, SFGM-TC and Cqwp-EBMT Result Type: Paper Number: 2581 Presenter: Erick Xavier Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 27. Outcomes after Double Umbilical Cord Blood Transplantation in Children: A Survey on Behalf of Eurocord and PDWP-EBMT Result Type: Paper Number: 2570 Presenter: Federica Giannotti Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 7 28. Unrelated Cord Blood Versus Non-T Cell Depleted Haploidentical Stem Cell Transplantation: Comparable Results in Adults with Acute Leukemia, a Eurocord and ALWP-EBMT Study Result Type: Paper Number: 1227 Presenter: Annalisa Ruggeri Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster I Time and Location: Saturday, December 6, 2014: 5:30 PM-7:30 PM North Building, Hall E (Moscone Center) 29. Comparison Between Related T-Cell Depleted HLA-Haploidentical Stem Cell Transplantation (TCD-Haplo) and Umbilical Cord Blood Transplantation (UCBT) in Pediatric Patients with Acute Leukemia, a Eurocord, PDWP-EBMT Study Result Type: Paper Number: 1215 Presenter: Franco Locatelli Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster I Time and Location: Saturday, December 6, 2014: 5:30 PM-7:30 PM North Building, Hall E (Moscone Center) 30. The Hierarchy of Alternative Donors for Allogeneic Hematopoietic Stem Cell Transplantation in Poor Risk AML in CR1: 10/10 Matched Unrelated Donors Still to be Preferred over Haplo-Identical Donors or Umbilical Cord Blood Result Type: Paper Number: 681 Presenter: Jurjen Versluis Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Haploidentical and Beyond Time and Location: Monday, December 8, 2014: 4:30 PM-6:00 PM West Building, 3005-3007 (Moscone Center) 31. Myeloablative Versus Reduced Intensity Allogeneic Stem Cell Transplantation in Relapsed Hodgkin’s Lymphoma in Recent Years. a Retrospective Analysis of the Lymphoma Working Party of the European Group for Blood and Marrow Transplantation Result Type: Paper Number: 2562 Presenter: Sonja Genadieva Stavrik Program: Oral and Poster Abstracts Session: 732. Clinical Allogeneic Transplantation: Results: Poster II Time and Location: Sunday, December 7, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 8 32. Genetic Determinants of Busulfan Clearance and Outcomes in Pediatric Patients Undergoing Hematopoietic Stem Cell Transplantation- Result of a Multicentric Prospective Study on Behalf of the Pediatric Disease Working Party of the European Blood and Marrow Transplantation Group Result Type: Paper Number: 424 Presenter: Marc Ansari Program: Oral and Poster Abstracts Session: 721. Clinical Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Transplant Toxicities: Personalizing Transplant Outcomes Time and Location: Monday, December 8, 2014: 10:30 AM-12:00 PM West Building, 3001-3003-3014-3016 (Moscone Center) 33. Safety and Efficacy of Thiotepa-Based Conditioning Therapy for Allogeneic Transplantation in Acute Myeloid Leukemia - a Survey from the Acute Leukemia Working Party of the European Group for Blood and Marrow Transplantation Result Type: Paper Number: 3895 Presenter: Sandra Eder Program: Oral and Poster Abstracts Session: 721. Clinical Allogeneic Transplantation: Conditioning Regimens, Engraftment and Acute Transplant Toxicities: Poster III Time and Location: Monday, December 8, 2014: 6:00 PM-8:00 PM North Building, Hall E (Moscone Center) 9
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