SOCOMUN XXIV Pan American Health Organization (PAHO) Chagas Disease Hello delegates, my name is Daniela Leon, and I will be one of your co-chairs for this year’s SOCOMUN conference! I am senior this year, have been in MUN all four years, and have been a part of the SOCOMUN secretariat since sophomore year. Also in sophomore year, I attended a conference at Berkeley University, and this year I will be attending a conference in Panama. I really like MUN because it has helped me develop great public speaking skills and leadership abilities. It has been a great way to meet new people from all over the world and it has brought to light all of the issues that are plaguing our world. It is really cool to hear issues on the new or in conversations and be able to get involved and share your ideas on the subject. My favorite committees are UNICEF and WHO, but I am always going into different committees so I can see all the different issues we have to face as a community today. I am in Advanced Dance at SMCHS and am in all of the department’s shows, and I am a competitive dancer with a studio outside of school. I really hope that SOCOMUN will be a great experience for all of you, and I hope that it will encourage you to continue in MUN. We will be discussing the topic of Chagas disease as our main topic, and if we have some extra time at the end of committee we will move on to our emergency topic which is Tuberculosis. I encourage you all to participate in committee and during caucus so you can get the most out of this conference. If you have any questions about the committee, the topic, MUN, or anything else, feel free to email me at [email protected] anytime! I can’t wait to see you all in committee! Background: Chagas, or Trypanosoma cruzi, is a very serious and life threatening disease that is not well known, but can be compared to diseases such as malaria and cholera as it is caused by the protozoan parasite and transmitted through insects. It has infected around seven million people, and its seriousness is exemplified as the disease claims 12,500 lives each year. The disease was first seen in humans in 1909. It would take another ninety years before the disease properly recognized and treatment instigated through organizations such as Doctors Without Borders. Unfortunately, many cases remain undetected and improperly treated, resulting in fatal damage to the heart, digestive system, and nervous system. Cases are most common in the southwestern United States, Central America, and Latin America. The disease itself has two stages: acute and chronic. Even with modern medical techniques, both stages of Chagas is very difficult to detect. During the acute stage of Chagas, minute symptoms include: body aches, inflammatory skin chamogas, fatigue, and vomiting. It is very difficult to detect in this stage because it closely resembles the symptoms of many other pathogens. After going through the acute stage, Chagas enters into the chronic stage. In this stage, symptoms can include constipation, digestive problems, difficulty swallowing, and abdominal pains. Detection is nearly impossible because the disease can enter remission and halt all symptoms for many years. An important aspect in understanding the disease itself is how it is transmitted. It is a SOCOMUN XXIV parasitic disease that is transmitted by the triatomines insect. It is most common in urban slums across Latin America because the insects live in the walls and roofs of mud and straw houses. These bugs come out at night to eat, which is when human contact most likely occurs. This is not however, the only way the disease can be transmitted. It is also known to be spread through bodily fluid contact such as blood transfusions, organ transplants, breastfeeding, and in the womb. It has also been recorded to spread through eating or drinking infected food and water, although very rare, as protozoan parasites can inhabit these resources. The biggest issues that come with the disease is diagnosis and treatment. In order to test for the parasite, doctors need to do at least three blood tests, but thee tend to be expensive, hard to acquire, and sometimes inadequate and inaccurate. It is also difficult because it needs to be treated in the acute stage, and a person can contract the disease again even after treatment. Another issue is the controlling of the vector. In this case, the vector is the disease carrying insect, and it is very hard to control their population, making it even more difficult to successfully treat those infected with the disease and lowering the chances of being infected again. Possible Solutions: All these solutions are being provided to help you begin forming your own solutions. While you can use these, I encourage you to create your own solutions so you can be more involved during committee. Please make sure that your solutions go along with your country’s policy, and that you do not contradict what you are proposing (for example, if your country is against the death penalty, you cannot propose to use the death penalty at any time during committee). Additionally, funding shall not be an issue because PAHO will cover costs, but finding organizations such as Doctors Without Borders can help bolster solutions. A solution that can be proposed is the continuation of researching Chagas disease and its treatments. Continuing research projects such as Chagas Implementation of Research Project, or CIRP, can greatly contribute to finding a quick and effective treatment of the disease. It can also be used to further public awareness on the Chagas disease and its causes, effects, and treatment. It would be a great way to spread the information to the general populace, especially those who underestimate the issue to its full extent. It can also be helpful to extend the information to those in the public that are impoverished and need the extension to learn the dangers they are in. This solution can be further expanded through the partnership of existing NGO’s , which will help countries work together and advance aspects of global awareness, disease research, treatment research, and different rural and urban treatment techniques. Another solution that could be proposed is the use of alternatives that are effective, safe, and non-toxic. This would be encouraged, but while these new alternatives are found, it is highly encourages that the uses of Nifurtimox and Benznidazole are continued. This along with the endorsement of more permanent and mobile health care clinics would help maximize the treatment and make it more available to people living in urban and rural areas. SOCOMUN XXIV Questions to consider: The following questions are provided for you to think about while you do your research. You do not need to specifically answer these questions for the conference, they are here to help you progress your ideas. 1. What are the main areas in diagnosis and treatment that could use the most improvement to help find a solution to the disease? 2. What forms of medicine could be produced to more effectively treat the disease? 3. In what ways could we control the vector without causing any harm to the environment, but still control it enough to make it easier to control the disease? 4. Do you think the means of treatment and diagnosis have a good base and could be built upon to find a more successful solution? 5. If yes, what changes can we make and how would you implement them? 6. If know, what other forms of treatment would you use and how would they be more successful than the ones used today? 7. What has been the major issue that has stumped doctors and scientist when finding a quick and efficient way of treating Chagas? 8. What treatments have worked in the past and how can we continue and progress off of these treatments? 9. How can we make the means of diagnosis and treatment more available to everyone (more supply, less expensive, more distribution areas, etc.)? SOCOMUN XXIV Works Cited "Chagas." MSF USA. N.p., n.d. Web. 20 Apr. 2015. <http://www.doctorswithoutborders.org/our-work/medical issues/chagas?utm_source=google&utm_medium=ppc&utm_campaign=chagas>. N.p., n.d. Web. 20 Apr. 2015. <http%3A%2F%2Fwww.medicinenet.com%2Fchagas_disease%2Farticle.htm>. "Chagas Disease (American Trypanosomiasis) ." Chagas Disease (American Trypanosomiasis). N.p., n.d. Web. 20 Apr. 2015. <http://emedicine.medscape.com/article/214581-overview>. "Chagas Disease (American Trypanosomiasis)." WHO. N.p., n.d. Web. 20 Apr. 2015. <http://www.who.int/mediacentre/factsheets/fs340/en/>. "History." The Chagas Disease Foundation. N.p., n.d. Web. 20 Apr. 2015. <http://www.chagasfound.org/chagas-disease-info.php?ID=4&t=History>. "Chagas Disease: Potentially a Life-threatening Neglected Tropical Disease." WHO. N.p., n.d. Web. 20 Apr. 2015. <http://www.who.int/chagas/en/>. "Detailed FAQs." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 19 July 2013. Web. 20 Apr. 2015. <http://www.cdc.gov/parasites/chagas/gen_info/detailed.html>. Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 19 July 2013. Web. 20 Apr. 2015. <http://www.cdc.gov/parasites/chagas/>. Tarleton, Rick L. CHAGAS DISEASE IMPACT AND OPPORTUNITIES: BEYOND THE HISTORICAL DOGMA. U.S. National Library of Medicine, n.d. Web. 20 Apr. 2015. <http://www.ncbi.nlm.nih.gov/books/NBK62523/>. "Chagas." - DNDi. N.p., n.d. Web. 20 Apr. 2015. <http://www.dndi.org/diseases projects/diseases/chagas.html>. SOCOMUN XXIV Pan American Health Organization (PAHO) Tuberculosis Background: Tuberculosis, or also known as TB, is a major problem worldwide. The World Health Organization announced that tuberculosis, second to HIV/AIDS, as one of the most infectious diseases on the planet. In 2013, 9 million people were infected and 1.5 million died of the disease, 95% of these fatalities occurring in low-income countries. Tuberculosis is an infectious disease that can attack any part of the body, but is most commonly known to attacks the lungs. Its symptoms include cough with sputum and blood at times, chest pains, weakness, weight loss, fever and night sweats. Tuberculosis is an extremely infectious airborne disease that is spread from person to person. Transmission occurs when a person with tuberculosis coughs, sneezes, laughs, sings, or even talks, because it causes TB to enter the air. After contact with infected air or another infected person, another acquires the disease, however repeated close contact is necessary for transmission. It is important to note the difference between being infected with TB and simply having the disease present in the body. A person who is infected with the TB has a high quantity of the infectious bacteria in their body, displays symptoms, and is capable of spreading the disease. TB can be present within the body and not display any symptoms. It is important to note that about one-third of the world's population has latent TB, which means people have been infected by TB bacteria but are not (yet) ill with the disease and cannot transmit it. Anyone with the disease present should consult a doctor immediately and receive treatment as soon as possible. 37 million lives were saved by proper diagnosis and treatment between 2000 and 2013. However, the overuse of antibiotics when treating the disease has led to the development of a multidrug resistant strain of TB known as MDR-TB. 480,000 contracted this strain in 2013, making it very difficult to combat. However, some cases are effectively treated due to proper immune response. When combined with HIV/AIDS, it can result in a fatal combination which result in an increase of the progress of both pathogens. 25% of HIV-positive patients are TB related. Cases are concentrated in 22 nations and with improving health care facilities coupled with WHO’s support, the number of reported TB cases are slowly declining. Possible Solutions: All these solutions are being provided to help you begin forming your own solutions. While you can use these, I encourage you to create your own solutions so you can be more involved with the topic and during committee. Please make sure that your solutions go along with your country’s policy, and that you do not contradict what you are proposing (for example if your country is against the death penalty, you cannot propose to use the death penalty at any time during committee). All costs, again, shall be covered by PAHO. A solution that can be proposed could be the support of NGO’s and research projects/programs so they can continue their research on tuberculosis and its different treatment means. Spreading awareness of the disease so the general public understands the seriousness and the consequences that comes with this disease. Many people don’t know SOCOMUN XXIV or understand how this disease is the second greatest killer, so we need to find ways to distribute this information to people all over the world. In developed nations, the use of media can be very influential and educational. In under developed nations, the UN can send teaching seminars about diseases such as tuberculosis and HIV/AIDS so that poverty stricken people can have access to information about the diseases and their treatments. Another solution that could be promoted is the implementation of more permanent and mobile health care centers. These would open up more availability of treatment and its options to those living in urban slums and impoverished areas. They would provide health care in all forms but most importantly in treatment for diseases such as tuberculosis. Questions to Consider: The following questions are provided for you to think about while you do your research. You do not need to specifically answer these questions for the conference, they are here to help you progress your ideas. 1. What have been the major causes of the tuberculosis disease spreading? 2. Why are have some people’s bodies adapted and learned to fight against TB, causing most people who have been infected by the disease not be affected? 3. How can we have more availability of treatment centers and of treatment itself so all people can have fair access and be able to be healed? 4. How can we reduce the disease’s efficiency in spreading through the air? 5. What NGO’s have been working to help this issue, and how are they doing so? 6. Have they been making progress? If so, how can we implement this on a global scale to advance as a community? 7. What NGO’s can be partnered together to be even more efficient in finding a solution and how? 8. What out of the box solutions can you come up with to solve this issue? (Be reasonable and logical in your solution, but try to be unique! Use your knowledge and critical thinking) SOCOMUN XXIV Works Cited "Background Information - Tuberculosis - Infectious Diseases Prevention, Control & Outbreak Management - Leeds, Grenville and Lanark District Health Unit." Background Information - Tuberculosis - Infectious Diseases Prevention, Control & Outbreak Management - Leeds, Grenville and Lanark District Health Unit.N.p., n.d. Web. 25 Apr. 2015. <http://www.healthunit.org/infectious/tb/tb_background.htm>. "National TB Indicators Project: Initial Indicators and Performance Targets." Centers for Disease Control and Prevention. Centers for Disease Control and Prevention, 01 Sept. 2012. Web. 25 Apr. 2015. <http://www.cdc.gov/tb/programs/evaluation/indicators/background.htm>. Greenland, Sander. "Putting Background Information about Relative Risks into Conjugate Prior Distributions." Biometrics 57.3 (2001): 663-70. Web. "Background and Objectives." WHO/Europe |. N.p., n.d. Web. 25 Apr. 2015. <http://www.euro.who.int/en/health-topics/communicable diseases/tuberculosis/news/news/2010/03/tbhiv-workgroup-meeting-focused on-europe-and-central-asia/background-and-objectives>. "History of Tuberculosis." News-Medical.net. N.p., 11 Dec. 2009. Web. 25 Apr. 2015. <http://www.news-medical.net/health/History-of-Tuberculosis.aspx>. "CATIE News." Tuberculosis & HIV-background Information. N.p., n.d. Web. 25 Apr. 2015. <http://www.catie.ca/en/catienews/2012-12-04/tuberculosis-hiv background-information>. Rther, Pharmacists Can Assist Other Public And Private Care Providers By Ensuring Rational Use Of , Anti-‐Tb Medicines And Contributing To Preventing Emergence Of Drug Resistance. , •, and For Example: Concerted Efforts In Collaboration With Pharmacists, Pharmaceutical Industry Pharmacists in TB Control: Their Current Role (n.d.): n. pag. Web. "TB Background Document: New Faces of an Old Disease." TB Background Document: New Faces of an Old Disease. N.p., n.d. Web. 25 Apr. 2015. <http://www.msfaccess.org/content/tb-background-document-new-faces-old disease>. "Tuberculosis (TB)." Tuberculosis in History. N.p., n.d. Web. 25 Apr. 2015. <http://www.niaid.nih.gov/topics/tuberculosis/understanding/history/pages/de ault.asp> National Collaborating Centre for Chronic Conditions (UK). Introduction. U.S. National Library of Medicine, n.d. Web. 25 Apr. 2015. <http://www.ncbi.nlm.nih.gov/pubmedhealth/PMH0046799/>.
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