Chapter 10
DNA Replication
and Recombination
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Chapter Contents
10.1 DNA Is Reproduced by Semiconservative
Replication
10.2 DNA Synthesis in Bacteria Involves Five
Polymerases, as well as Other Enzymes
10.3 Many Complex Tasks Must Be Performed
during DNA Replication
10.4 A Summary of DNA Replication in
Prokaryotes
10.5 Replication in Prokaryotes Is Controlled
by a Variety of Genes
Continued
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10.6 Eukaryotic DNA Synthesis Is Similar to
Synthesis in Prokaryotes, but More
Complex
10.7 Telomeres Provide Structural Integrity at
Chromosome Ends but are Problematic
to Replicate
10.8 DNA Recombination, Like DNA
Replication, Is Directed by Specific
Enzymes
10.9 Gene Conversion Is a Consequence of
DNA Recombination
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Section 10.1: DNA Is Reproduced by
Semiconservative Replication
• The complementarity
of DNA strands
allows each strand to
serve as a template
for synthesis of the
other.
(Figure 10.1)
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Section 10.1
• Three possible modes of DNA replication
are possible:
• conservative
• semiconservative
• dispersive
(Figure 10.2)
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Copyright © 2009 Pearson Education, Inc.
Figure 11.2
Section 10.1
• The Meselson-Stahl experiment
demonstrated that:
• DNA replication is semiconservative
• each new DNA molecule consists of one old
strand and one newly synthesized strand
(Figure 10.3 and Figure 10.4)
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Section 10.1
• The Taylor-Woods-Hughes experiment
demonstrated that DNA replication is
semiconservative in eukaryotes
(Figure 10.5)
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Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Copyright © 2009 Pearson Education, Inc.
Section 10.1
• DNA replication
begins at the
origin of
replication and
is bidirectional
rather than
unidirectional
(Figure 10.6).
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Section 10.1
• A replicon is the length of DNA that is
replicated following one initiation event at
a single origin.
Copyright © 2009 Pearson Education, Inc.