New tools and approaches for nanomaterial safety assessment A joint conference organized by NANOSOLUTIONS, SUN, NanoMILE, GUIDEnano and eNanoMapper HOTEL BARCELÓ MÁLAGA | 7 – 9 FEBRUARY 2017 CONFERENCE PROGRAMME DAY 1 | TUESDAY, 7TH FEBRUARY 2017 12.30 – 14.00 pm Lunch (Lobby) 12.30 – 14.00 pm Registration (Lobby) 14.00 – 14.30 pm Opening Session (Andalucia 1) Excelentísimo Alcalde de Málaga, Sr. Francisco Manuel de la Torre Prados Segebarth on behalf of DG Research, European Commission / EU Nanosafety Cluster Pilar de Miguel Ortega on behalf of CDTI (Centre for the Development of Industrial Technology), Spanish Ministry of Economy Socorro Vázquez-Campos (LEITAT Technological Center) – local host and Coordinator of GUIDEnano Keynote 1: GUIDEnano Keynote: GUIDEnano: A tool for Risk assessment of nanomaterials and nano-enabled products (Andalucia 1) Socorro Vázquez-Campos (LEITAT Technological Center) Introduced by: Claus Svendsen (Centre for Ecology and Hydrology) Parallel Session 1: Exposure assessment along the life cycle of nano- Parallel Session 2: Risk assessment & management enabled products (Andalucia 1) (Andalucia 2+3) Chairs: Claus Svendsen and Antonio Marcomini Chairs: Barry Hardy and Benoit Hazebrouck Vladimir Mirsky (Brandenburgische Technische Universität): Detection, Pasquale Bove (Fondazione Istituto Italiano di Tecnologia Genova): quantification and identification of engineered nanoparticles at ppbDissolution test for risk assessment of nanoparticles – a pilot study concentrations in complex media Ana Sofia Fonseca (NRCWE): Goodness of dustiness index for predicting Chiara Civardi (EMPA): Assessing the effectiveness and environmental risk human exposure to airbourne nanomaterials of nanocopper-based wood preservatives 14.30 – 15.15 pm 15.15 – 16.00 pm 15.15 – 15.30 pm 15.30 – 15.45 pm 15.45 – 16.00 pm 16.00 – 17.00 pm 17.00 – 18.15 pm 17.00 – 17.15 pm 17.15 – 17.30 pm 17.30 – 17.45 pm 17.45 – 18.00 pm 18.00 – 18.15 pm 18.15 – 18.30 pm Alejandro Vílchez (LEITAT): Lab-scale simulations to quantify nanomaterials release from nano-enabled products (Nanosolutions) Coffee break & Poster session 1 (Lobby) Parallel Session 1 (continued) (Andalucia 1) Michael Steinfeldt (University of Bremen): Hot-spot release mapping of nanomaterials – a visual exposure assessment method for preliminary assessment (SUN highlight) Bernd Nowack (EMPA): Meeting the needs for released nanomaterials required for further testing – the SUN approach (SUN highlight) Jose Luis Muñoz Gómez (LEITAT): Experimental life-cycle simulations of nano-enabled products and characterisation of released materials Tarryn Lee Botha (North West University): Swimming performance and behavioural changes in zebrafish (Danio Rerio) after exposure to nanomaterials Keld Alstrup-Jensen (NRCWE): The SUN tiered modelling based inhalation, dermal, oral and inadvertent oral exposure assessment framework for nanomaterials (SUN highlight) Araceli Sanchez Jimenez (IOM): Exposure Assessment of GUIDEnano case studies (GUIDEnano highlight) Maaike le Feber (VITO): NanoStreeM to assess exposure and risks of nanomaterials in nanoelectronics manufacturing Parallel Session 2 (continued) (Andalucia 2+3) Philip Doganis (NTUA): Nanomaterials computations in your browser: predictions, read-across, experimental design and interlaboratory comparison using the JAQPOT modelling platform (eNanoMapper highlight) Wouter Fransman (TNO): Nano-specific risk management measures (RMM) and a proposal for effectiveness factors for modelling purposes. (GUIDEnanohighlight) Vesa Hongisto (Misvik Biology): A High-Throughput Screening Approach Evaluated Toxicity of 31 Engineered Nanomaterials Generated for the NANOSOLUTIONS Project (NANOSOLUTIONS highlight) Socorro Vázquez Campos (LEITAT): GUIDEnano: A web-based Tool for Risk assessment of nanomaterials and nano-enabled products (GUIDEnano highlight) Alex Zabeo (Ca'Foscari University Venice): SUNDS, a multi-criteria based decision support system for nanotechnology risk assessment and management (SUN highlight) Ineke Malsch (Malsch TechnoValuation): Decision support in collective dialogue on international regulation of nanomaterials DAY 2 | WEDNESDAY, 8TH FEBRUARY 2017 09.00 – 09.45 am 09.45 – 10.30 am 09.45 – 10.00 am Keynote 2: NANOSOLUTIONS Keynote: NANOSOLUTIONS: Towards ENM Safety Classification (Andalucia 1) Presenter: Harri Alenius (University of Helsinki) Introduced by: Kai Savolainen (Finnish Institute of Occupational Health) Parallel Session 3: Hazard assessment along the life cycle of nanoParallel Session 1 (continued): (Andalucia 2+3) enabled products (Andalucia 1) Chairs: Danail Hristozov and Bernd Nowack Chairs: Flemming Cassee and Richard Handy Valentina Ricottone (Heriot-Watt University): Chronic ecotoxicity of Denise Mitrano (EMPA): Life-cycle inspired protocols for aging copper oxide nanomaterials to the pond snail Lymnaea Stagnalis engineered nanomaterials: Applicability of comparing pristine and 10.00 – 10.15 am Katrin Loeschner (Technical University of Denmark): Solutions to practical challenges in developing dispersion procedures for nanoparticle characterisation and toxicological testing 10.15 – 10.30 am Taina Palosaari (JRC): On the Fast Track towards in vitro screening of manufactured nanomaterials (NanoMILE highlight) Coffee break (Lobby) Parallel Session 3 (continued) (Andalucia 1) Audrey Gallud (Karolinska Institutet): Cytotoxicty screening of panel of 31 nanomaterials in the human monocytic cell line THP.1 versus primary human monocye-derived macrophages: assessing the role of surface modifications (NANOSOLUTIONS highlight) Hannu Norppa (FIOH): Genotoxicity of 31 nanomaterials in human bronchial epithelial cells (NANOSOLUTIONS highlight) Kukka Aimonen (FIOH): In vivo genotoxic and inflammatory effects of a self-cleaning agent containing silver-doped TiO2 nanoparticles 10.30 – 11. 00 am 11.00 – 12.30 pm 11.00 – 11.15 am 11.15 – 11.30 am 11.30 – 11.45 am 11.45 – 12.00 pm Tina Buerki-Thurnherr (EMPA): A 3D human co-culture microtissue model for nanoparticle effect and uptake studies at the placental barrier 12.00 – 12.15 pm Fritz Krombach (LMU Munich): The endothelial glycocalyx controls interactions of engineered nanomaterials with the vessel wall and their translocation across the blood tissue border (NANOSOLUTIONS highlight) transformed particles to understand nanoparticle behaviour and (eco)toxicity (NanoMILE highlight) Rute Ferreira Domingos (Institut de Physique du Globe de Paris) A kinetic environmental fate model for the risk assessment of engineered nanomaterials (GUIDEnano highlight) David Boyle (Plymouth University): Assessment of dietary uptake of copper oxide nanomaterials in rainbow trout using an in vitro gut sac technique Parallel Session 1 (continued) (Andalucia 2+3) María Blázquez (Inkoa Sistemas SL): Integration of ecotoxicological effect of ENMs into life cycle impact assessment Michael Steinfeldt (University of Bremen): Life cycle thinking of nanotechnology based applications Parallel Session 4: Systems Biology (Andalucia 2+3) Chairs: Carsten Weiss and Harri Alenius Roman Zubarev (Karolinska Institutet): Cytotoxic and Pro-inflammatory Effects of Metal-based Nanoparticles on THP-1 Monocytes Characterized by Combined Proteomics Approaches (NANOSOLUTIONS highlight) Pekka Kohonen (Karolinska Institutet): In silico capture of toxicity effects related to nanomaterials using a novel predictive toxicogenomics space tool (eNanoMapper highlight) Anna von Mikecz (Leibniz Research Institute of Environmental Medicine): Nanoparticle-induced protein fibrillation and neurodegeneration cascades in the nematode Caenorhabditis Elegans 12.15 – 12.30 pm 12.30 – 14.00 pm 14.00 – 14.45 pm 14.45 – 15.30 pm 14.45 – 15.00 pm 15.00 – 15.15 pm 15.15. – 15.30 pm 15.30 – 16.30 pm 16.30 – 18.15 pm 16.30 – 16.45 pm José M. Navas (Spanish National Institute for Agricultural and Food Penny Nymark (Misvik Biology): A pathway tool for applying “big data” Research and Technology (INIA)): Development of an in vitro method to in nanosafety – focussed read across the adverse outcomes studies study long-term effects of copper nanoparticles on fish cell lines (eNanoMapper highlight) Lunch (Lobby) Keynote 3: SUN Keynote: SUN: EU project developing tools to facilitate assessment and management of nanotechnology risks (Andalucia 1) Presenters: Danail Hristozov (Ca' Foscari University of Venice), Wendel Wohlleben (BASF), Janeck Scott-Fordsmand (Aarhus University), Keld AlstrupJensen (NRCWE), Vicki Stone (Heriot-Watt University), Terry Wilkins (University of Leeds) and Antonio Marcomini (Ca' Foscari University of Venice) Introduced by: Danail Hristozov Parallel Session 3 (continued) (Andalucia 1) Parallel Session 4: Systems Biology (continued) (Andalucia 2+3) Chairs: Vicki Stone and Julia Catalan Chairs: Carsten Weiss and Harri Alenius Charles Tyler (University of Exeter): Novel models and approaches for assessing nanoparticle exposure & effects in fish (NanoMILE highlight) Janeck Scott-Fordsmand (Aarhus University): Novel tools for hazard on ecosystems services and ecological risk assessment of NMs (SUN highlight) M. Luisa Fernández-Cruz (National Institute for Agricultural and Food Research and Technology): Looking into a pattern between nanoparticle coating and toxicity to aquatic organisms Coffee & Poster session 2 (Lobby) Parallel Session 3 (continued) (Andalucia 1) Willie Peijnenburg (RIVM): Are there significant acute ecotoxicological effects of nanoparticles? 16.45 – 17.00 pm Wim H De Jong (RIVM): Toxicity of copper oxide and copper carbonate nanoparticles after short terms oral exposure 17.00 – 17.15 pm P. Kinaret (University of Helsinki): Cellular and molecular responses to engineered nanomaterials on murine airways in vivo 17.15 - 17.30 pm Tina Wahle (Leibniz Research Institute for Environmental Medicin): Neurological effects of inhaled nano-sized cerium dioxide in a mouse model of Alzheimer's disease and wildtype mice (NanoMILE highlight) Cyrill Busey (University of Manchester): Splenic Capture and Degradation of Graphene Oxide In Vivo 17.30 – 17.45 pm Roman Zubarev (Karolinska Institutet): Omics workflows implemented in the NANOSOLUTIONS project Vladimir Lobaskin (University College Dublin): Modelling bionano interactions for predictive Toxicology Egon Willighagen (Maastricht University): Answering Scientific Questions with linked European nanosafety data (eNanoMapper highlight) Parallel Session 4: Systems Biology (continued) (Andalucia 2+3) Vittorio Fortino (University of Helsinki): ENM SAFETY CLASSIFIER – A multi-view feature selection and classification algorithm for prediction of engineered nanomaterials (ENM) safety. (NANOSOLUTIONS highlight) Alexandra Murschhauser (LMU Munich): Event Correlations in the Apoptosis Signalling Cascade gained from Single Cell Time-lapsed Analysis Angela Serra (University of Salerno): A network based data integration tool for the contextualiszation of engineered nanomaterials (ENM) mode of action Nina Jeliazkova (Ideaconsult Ltd): Mapping the Nanosafety cluster data (eNanoMapper highlight) Andrew Nelson (University of Leeds): A Rapid high throughput screening platform for nanomaterials 17.45 – 18.00 pm 18.00 – 18.15 pm 20.00 – 22.00 pm Elisabeth Joossens (JRC): High-throughput analysis allows building a database to screen toxicity of nanomaterials Margriet Park (RIVM): Hazard evaluation in GUIDEnano: A web-based guidance tool for risk assessment and mitigation of nano-enabled products (GUIDEnanohighlight) Olivier Joubert (Université de Lorraine): Smartnanotox: Smart tools for gauging nano-hazards Christoph Helma (Silico Toxicology gmbh): Nano-Lazar: A framework for nanoparticle read across risk assessment (eNanoMapper highlight) Gala Dinner (with prior registration) (Los Patios de Beatas, Calle Beata 43) DAY 3 | THURSDAY, 9TH FEBRUARY 2017 09.00 – 09.45 am 09.45 – 10.30 am 09.45 – 10.00 am 10.00 – 10.15 am 10.15 – 10.30 am 10.30 – 11. 00 am 11.00 – 12.30 pm 11.00 – 11.15 am Keynote 4: NanoMILE Keynote: Towards mechanistic understanding of nanomaterials interactions: a hazard assessment framework (Andalucia 1) Presenter: Eva Valsami-Jones (University of Birmingham) Introduced by: Carsten Weiss (Karlsruhe Institute of Technology) Parallel Session 5: Safety by Design (Andalucia 1) Parallel Session 6: Categorisation and Grouping of NMs (Andalucia Chairs: Eva Valsami-Jones and Andreas Falk (TBC) 2+3) Chairs: Egon Willighagen and Iseult Lynch Jesús López de Ipiña (Tecnalia): A methodological approach for the safe David Asturiol (JRC): Applying ECHA recommendations on grouping and deisgn and putting into service of new processes for manufacturing cntread-across of nanomaterials to predict in vitro genotoxicity of titanium nano-enabled products dioxide (TiO2) Zahraa Al-Ahmady (University of Manchester): Size dependent internalisation profile of PEGylated multi-walled carbon nanotubes and the impact of protein adsorption Changyou Gao (Zhejiang University): Influences of gold nanoparticles with surface anchored chiral poly(acryloyl-l(D)-Valine) on protein adsorption, cellular uptake and cytotoxicity Coffee break (Lobby) Parallel Session 5 (continued) (Andalucia 1) Sophie Marie Briffa (University of Birmingham): Importance of multimethod characterisation approach in the development and behavioural understanding of nanomaterial libraries for nanosafety studies: polyvinylpyrrolidone (PVP)-capped metal oxide nanoparticles (NanoMILE highlight) Diluka Peiris (Attana): Cell based biosensor approach to characterize nanomaterial-cell surface receptor interactions (NanoMILE highlight) Mary Gulumian (NIOH): Surface ligands and functional groups on the surfaces of nanomaterials as determinants of their intracellular uptake and toxicity: A consideration for the grouping of nanomaterials Parallel Session 6 (continued) (Andalucia 2+3) Joanne Vassallo (Plymouth University): Modifying the minimum inhibition centration (MIC) assay from pharmaceutical testing to a method for screening bacterial toxicity of engineered nanomaterials, in combination with a systems biology approach 11.15 – 11.30 am 11.30 – 11.45 am 11.45 – 12.00 pm 12.00 – 12.15 pm 12.15 – 12.30 pm 12.30 – 14.00 pm 14.00 – 14.45 pm 14.45 – 16.15 pm Carolin Merker (University of Leipzig): Translocation and quantification of Silvia López-Vidal (IONER): Electrospray deposition system as sample nanomaterials as single cell level by means of label-free imaging and preparation technique for nanoparticle analysis by electron microscopy dosimetric techniques Vicki Stone (Heriot-Watt University): An in vitro and in vivo strategy to Anastasios Papadiamantis (University of Birmingham): The impact of prioritise nanomaterials for toxicity testing and to inform safety-byengineered nanoparticles on aquatic species: an ISA-TAB compatible design dataset minded from the literature (2007-2016) (SUN highlight) Magda Blosi (Institute of Science and Technology for Ceramics): Demetra-Danae Varsoy (NTUA): Exploring correlation patterns on toxicity Justification of safer-by-design solutions for CuO-NPS: a case study omics data Anna Luisa Costa (National Research Council of Italy): Safer nanoMargriet Park (RIVM): Implementation of read-across between product and processes by design (nano)materials for hazard assessment in GUIDEnano (SUN highlight) (GUIDEnanohighlight) Sandra Verstraelen (VITO): Safety-by-design in practice: metallic nano John Rumble (Codata): Describing nanomaterials accurately in support of inks for printed electronics and nano-modified alloys for additive categorisation and read-across manufacturing Lunch (Lobby) Keynote 5: eNanoMapper Keynote: Advancing a Sustainable Knowledge Infrastructure for the Safety Assessment of Nanotechnology (Andalucia 1) Presenters: Barry Hardy (Douglas Connect GmbH), Egon Willighagen (Maastricht University), Nina Jeliazkova (IDEAconsult Ltd.) and Haralambos Sarimveis (The National Technical University of Athens) Introduced by: Egon Willighagen Stakeholder meeting (Andalucia 1) Panel discussion 1 (Chaired by Iseult Lynch and Danail Hristozov): Stakeholder engagement – lessons learned and the path forward for H2020 projects – multi-stakeholder perspectives Panelists: Aïda Ponce del Castillo (ETUI), Blanca Serrano Ramon (CEFIC), Daniel Bernard (AFNOR), David Warheit (Chemours), Jean-Marc Aublant (CEN), Michael Stintz (ISO), and Paul Schulte (NIOSH) Panel discussion 2 (Chaired by Socorro Vázquez-Camposand Kai Savolainen): 16.15 – 16.30 pm Ensuring the legacy of EU-funded project outputs: strategies and supports needed Panelists: Germ Visser (Royal DSM), Jose Mauro Granjeiro (Inmetro), Lisa Friedersdorf (NNCO), Maila Puolamaa (EC, DG GROW), Birgit SokullKluettgen (JRC Ispra), Peter Kearns (OECD), and Karin Wiench (BASF) Closing remarks: Iseult Lynch (University of Birmingham) and Kai Savolainen (Finnish Institute of Occupational Health) (Andalucia 1) Best poster awards Close of meeting (& refreshments) List of posters for Poster Session 1 (posters to be hung lunchtime on 7th Feb. until lunchtime on 8th Feb.) Posters addressing topics: Exposure assessment along the life cycle of nano-enable products Nanosafety infrastructure Risk assessment & management Categorisation and Grouping of NMs Exposure assessment along the life cycle of nano-enable products 1. #1516 Araceli Sánchez et al. (IOM), Dermal and dermal-to-oral exposure to nanomaterials 2. #1518 Nathaniel Clark et al. (Plymouth University), Investigation Of The Dietary Bioavailability Of Silver Nanoparticles in Rainbow Trout Using An Ex Vivo Gut Sac Technique. 3. #1538 Cecile Philippot et al. (CEA), Nanocomposites end-of-life studies: a way to improve their safe by design behaviour within the frame of the GUIDEnano European project 4. #1546 Willie Peijnenburg et al. (RIVM), 5. #1550 Ahmad Hussain et al. (NDRI University), In vitro exposure of ZnO nanoparticles and Mesoporous Silica nanoparticles on immune and male germ cells 6. #1558 Wouter Fransman et al. (TNO), LICARA nanoscan - A first tier tool for the self-assessment of benefits and risks of nanoproducts in the SUN decision support system 7. #1562 Mar Viana et al. (IDAEA-CSIC), Exposure to ceramic nanoparticles during plasma spraying 8. #1565 Roel Vermeulen et al. (TNO), Release of nanomaterials: nanomaterials integrated in car bumpers 9. #1567 Eelco Kuijpers et al. (TNO), Dermal model for nanomaterials 10. #1584 Maida Domat et al. (ITENE), Replicate of GUIDEnanocase studies under controlled conditions to support dispersion models 11. #1611 Marta Pérez-Cabo et al., (ICCRAM-University of Burgos), A multi approach study of the effect of the exposition to polystyrene nanoparticles on Daphnia magna 12. #1632 Effects of medium composition on the aquatic fate of copper nanoparticles Carlos Fito et al. (ITENE), Development of a real-time information and monitoring system to support the risk assessment of nanomaterials under REACH 13. #1651 David Garry / Marguerite Esquivel-Gaon et al. (University College Dublin), Assessing the biological identity of Titania (TiO2) nanoparticles via controlled surface coatings Nanosafety infrastructure 14. #1508 Tritsida Panyosak et al. (University of Phayao), Effects of azelaic acid in nanovesicles on cell lines selection 15. #1533 Andreas Falk et al. (BioNanoNet Forschungsgesellschaft mbH), Industrial innovation liaison (I2L – NSC sub-group as supporting infrastructure for real-life application of nanosafety assessment 16. #1670 Farcal et al. (Douglas Connect), eNanoMapper applications to support the risk assessment of nanomaterials 17. #1653 M. Rautenberg et al. (In Silico Toxicology gmbh), In Silico Toxicology test services 18. #1654 D. Gebele et al. (In Silico Toxicology gmbh), ENM-ontoviewer: interactive visualisation of sparql queries for enanomapper ontologies and data 19. #1655 Christoph Helma et al. (In Silico Toxicology gmbh), Integration of in Silico Toxicology services in the enanomapper infrastructure 20. #1656 Christoph Helma et al. (In Silico Toxicology gmbh), In Silico Toxicology services for nanoparticles risk assessment Risk assessment & management 21. #1502 Michael Steinfeldt et al. (University of Bremen), Design pronciples for ‘Green nano’ 22. #1559 Elena Semenzin et al. (University Ca' Foscari Venice), Assessing sustainability of nano-enabled products through the life cycle 23. #1560 Vrishali Subramanian et al. (University Ca' Foscari Venice), Controlling the human health and ecological risks of nano-enabled products through the life cycle 24. #1570 Georgios Drakakis et al. (National Techncal University of Athens), Using KNIME and Python to access and process eNanoMapper data 25. #1574 Jordi Palau et al. (ITENE), Building a web-based risk assessment and risk-management tool: nanomaterials treatment technologies 26. #1579 Susan Wijnhoven et al. (National Institute for Public Health and the Environment, RIVM), Development of a risk assessment strategy for the GUIDEnano tool 27. #1589 María Luisa et al. (National Institute for Agricultural and Food Research and Technology), A web-tool based approach to evaluate the quality of an (eco)toxicity study performed with nanomaterials 28. #1603 Rob Stierum et al. (TNO), Review of human risk assessment models for manufactured nanomaterials applicable during different stage gates of product innovation. First results from EU “CALIBRATE” project (WP2) 29. #1630 Carlos Fito et al. (ITENE), New tools to support the mitigation and control of the exposure to ENMs in the work place 30. #1635 Sofia Ricarte and Carlos industry Fito (ITENE), Advanced web based tools to promote the application of nanotechnology and safe use of nanomaterials in the plastic 31. #1639 32. #1643 Antreas Afantitis et al. (Novamechanics), NanoMILE QSARs, grouping and mechanistic hazard assessment platform 33. #1649 Javier Pla et al. (ITENE), Recommended technical, organizational and personal protective equipment to control the exposure to ENMs in research laboratories Lisa Pizzol and Danail Hristozov (University of Venice), Human health risk assessment module mplemented in sunds risk assessment and management Categorisation and Grouping of NMs 34. #1526 Raphael Brüngel et al. (University of Applied Science and Arts Dortmund), The nanodefiner e-tool for nanomaterial classification 35. #1535 Silvia López-Vidal et al. (RAMEM), Nanomaterial characterization is a challenging subject due to limitations in analysis method and representativity of sampling procedures 36. #1541 Silvia López-Vidal et al. (RAMEM), Novel high resolution differential mobility analyser (HDRMA) for size characterisation of nanoparticles smaller than 5nm 37. #1594 Maria Gianneli et al. (Attana AB), QCM-based method to predict in vivo behaviour of nanoparticles 38. #1604 Jian Liu et al., (University of Birmingham), Atomic Ordering Determined by Choice of Iron Salt Precursor in Continuous Hydrothermally Prepared Fe-Co Bimetallic Nanoparticles 39. #1622 Franky Puype et al. (Institute for Testing and Certification) European standardization project on detection and identification of nano-objects in complex matrices: Evaluating sample preparation methods and end-characterization methods 40. #1631 Zahraa Al-Ahmady and Kostas Kostarelos (University of Manchester), Preparation and Characterisation of functionalised multi-walled carbon nanotubes List of posters for Poster Session 2 (posters to be hung lunchtime on 8th Feb. until lunchtime on 9th Feb.) Posters addressing topics: Hazard assessment along the life cycle of nano-enabled products Systems Biology Safety by Design Hazard assessment along the life cycle of nano-enabled products 1. #1501 Rob Vandebriel et al. (National Institute for Public Health and the Environment), Nanoparticle shape-dependent NLRP3 inflammasome activation 2. #1509 water Nhung Nguyen (Institute for Nanomaterials), The impact of nano-scale and micro-scale zero-valent iron particles on planktonic microorganisms in reservoir 3. #1510 Petra Rosická et al. (Institute for Nanomaterials), Biological effect of perovskite nanomaterial on Pseudomonas Putida and microorganism in activated sludge 4. #1517 Barbara Drasler et al. (University of Fribourg), Hazard assessment of aerosolized graphene-related materials in a 3D human alveolar tissue in vitro 5. #1524 Annette Piechulek et al. (Heinrich-Heine-University), From exposure to impact: Nanoecotoxicity studies in the nematode C. Elegans 6. #1534 Elisa Moschini et al. (LIST), Endothelial responses of the alveolar barrier in vitro in a realistic dose-controlled exposure to diesel exhaust particulate matter 7. #1542 Julia Catalán et al. (Finnish Institute of Occupational Health), Effect of coating on the in vivo toxicological potential of CeO2 NPs 8. #1544 Julia Catalán et al. (Finnish Institute of Occupational Health), Prediction of the mutagenic potential of nanomaterials within the GUIDEnano hazard assessment 9. #1545 Willie Peijnenburg et al. (RIVM), Nanoparticles, ions and shape governing soil microbial functional diversity: nano shapes micro 10. #1548 Andrea Brunelli et al. (Ca' Foscari University of Venice), Colloidal characterisation of nano-sized pigments in eco(toxicological media 11. #1556 Ingeborg Manita Kooter et al. (TNO), Toxicological Response Of Healthy And Asthmatic 3D in vitro airway model To CuO Particles At The Air-liquid Interface 12. #1573 Vivina Lopes et al. (Uppsala University), In vitro studies to investigate the relationship between different coatings and their effect on nanoparticle toxicity 13. #1575 Philip Doganis et al. (National Technical University of Athens), eNanoMapper tutorials: guidance to the infrastructure for nanomaterial modelling 14. #1586 Joan Cabellos et al. (LEITAT Technological center), Effect of coating on the intestinal absorption of CeO2 nanoparticles 15. #1593 Mark Miller et al. (University of Edinburgh), Free radical generation and atherosclerotic effects of redox modified cobalt oxide nanoparticles 16. #1600 Gerard Vales et al. (Finnish Institute of Occupational Health), Influence of size and surface functionalization on the genotixicity of gold nanoparticles 17. #1606 Kailen Boodhia et al. (National Institute for Occupational Health), The effect of physicochemical properties on the toxicity and intracellular uptake of Gold Nanoparticle on exposed BEAS-2B cells 18. #1610 19. #1613 Mona Connolly et al. (Heriot Watt University), The potential impact of engineered nanomaterials (ENMs) on marine ecosystems: investigations using the marine mussel Mytilus sp Marta Pérez-Cabo et al. (ICCRAM-University of Burgos), An integral study of graphene material safety on the eukaryotic model Saccharomyces cerevisiae. 20. #1615 Marianne Matzke et al. (Centre for Ecology and Hydrology), Impact of silver and silver nanoparticles on the structure and functionality of microbial communities in sewage treatment plants 21. #1616 Dirk Dressler et al. (BioTeSys GmbH), Genotoxicity of nanoparticles measured by the FADU assay - an automated assay for the assessment of DNA strand breaks in vitro 22. #1619 23. #1621 Sandra Vranic et al. (National Graphene Institute), Protein coronation is not fully protecting Beas-2b cells against toxicity of graphene oxide flakes of large lateral dimensions 24. #1626 Carolin L. Schultz et al. (Centre for Ecology and Hydrology), Can nanoparticle characteristics be used to rank toxicity to different organisms? 25. #1628 Rerio) Benjamin Shaw et al. (Plymouth University), The effects of surface coating on the toxicity of CuO engineered nanomaterials to early life-stage zebrafish (Danio 26. #1658 Iris Hansjosten et al. (Institute of Toxicology an Genetics), Microscopy-based high throughput assays enable multi-parametric analysis to assess adverse effects of nanomaterials in various cell lines 27. #1659 Sonja Mülhopt et al. (Karlsruhe Institute of Technology), Effect of cerium oxide nanoparticle aerosol on human lung cells exposed at the air-liquid interface 28. #1660 Marit Ilveset al.(University of Helsinki), Inflamatory Effect of CuO Nanomaterials in a Murine Model of Asthma 29. #1662 Adriana Sofranko et al. (IUF-Leibniz Research Institute for Environmental Medicine), Effects of SiO2 and CeO2 nanoparticles on alzheimer-like pathology in mice after 3 and 14 weeks oral exposure 30. #1669 Artur Filipe et al. (National Graphene Institute), Investigating the impact of lateral dimensions of graphene oxide flakes on the mesothelial membrane Marie Carriere et al. (Université Grenoble Alpes), Nanomaterial genotoxicity: the case of silver nanoparticles Systems Biology 31. #1551 Zhengwei Mao et al. (Zhejiang University), A high-thoruhgput approach to understand the toxicity mechanism of a supramolecular based nanoparticle with combinational chemotherapy and photodynamic therapy effect 32. #1555 Roberta Bartucci et al. (University of Groningen), Precision-cut tissue slides: a potential ex-vivo model for nanosafety studies Safety by Design 33. #1504 Peter Weyell et al. (University Jena), A concept for decision making on innovative iron oxide nanoparticles selection for a sustainable application in diagnostics 34. #1519 Cobaleda Siles et al. (Vall Hebron Research Institute), Development of optimal synthesis strategies for the reduction of nanotechnology associated risks 35. #1522 Dimiter Prodanov (IMEC), NANOSTREEM: Strategies for safety assessment in advanced integrated circuits manufacturing 36. #1537 Delphine Boutry et al. (CEA), NPs Release study turned towards the safer by design approach – different case studies investigated in thee GUIDEnanoEuropean approach 37. #1539 Changyou Gao et al. (Zhejiang University), The surface properties of nanomaterials dominate cellular uptake and differentiation of mesenchymal stem cells 38. #1549 Elena Badetti et al. (Ca' Foscari University of Venice), Characterisation and properties of modified CuO NPs in environmental and biological media 39. #1563 Ilse Gosens et al. (National Institute for Public Health and the Environment), Pulmonary toxicity of surface modified copper oxide nanoparticles 40. #1571 Susan Dekkers et al. (RIVM), Implications of redox activity of nanoparticlees on immunological pathways in vitro 41. #1572 Susan Dekkers et al. (RIVM), The influence of redox activity of inhaled nano-sized cerium dioxide on respiratory, immune and cardiovascular effects in multiple mouse models 42. #1585 43. #1592 Mark Miller et al. (University of Edinburgh), The effect of a cross-linked dextran coating on the potential thrombogenicity of superparamagnetic iron oxide nanoparticles 44. #1597 David Hernández-Moreno et al. (National Institute for Agricultural and Food Research and Technology), Ag NPs cytotoxicity differences related to primary particle size and functionalization 45. #1636 Jesús Lopez de Ipiña et al. (TECNALIA Research and Innovation), A methodological approach for the safe design and putting into service of new production process for manufacturing CNT-enabled products 46. #1640 Desirè Di Silvio et al. (CIC biomaGUNE), Iodine-124 chemisorption on metal nanoparticles with organic coating for in vivo biodistribution study Camilla Delpivo et al. (LEITAT technological center), Implementation of safe by design strategies in GUIDEnano: textile case study. Please be aware that this conference is being filmed. If you have any questions, please contact Tom Carney, NanoMILE Project Manager at [email protected] Check out and attend the additional workshop open to all interested conference participants! HACKATHON ON TEMPLATES FOR DATA COLLECTION TUESDAY, 7TH FEBRUARY 2017 Event place: Room Trinidad 2-3, Hotel Barceló, Malaga, (Spain) 09:00 - 12:30 The goal of this workshop preceding the NMSA Conference, is to make the participants familiar with the eNanoMapper solutions for data management and data access. We will demonstrate how https://search.data.enanomapper.net/ integrates various data sets, how you can search for materials and how to use the application programming interface (API) to access data. Participation on Hachathon is free of charge. Please register: http://doodle.com/poll/wu2vrxk8nqycr5av
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