ASCLS-NY Spring Seminar June 9, 2017 Definition of public health Description of the components of public health Characterization of the structure of the Laboratory Response Network Comparison of the roles of the clinical laboratory and the public health laboratory Description of the three testing areas of the Erie County Public Health Laboratory Overview of the role of the laboratory in a Sexually Transmitted Disease Clinic Discussion of career opportunities in public health laboratories for clinical laboratory scientists Differentiate between the role of the clinical laboratory and the public health laboratory Describe the testing required to detect communicable microorganisms, environmental toxins and irritants that have an adverse effect on human health Discuss career opportunities for clinical laboratory scientists in the public health laboratory The body of knowledge dealing with illnesses that affect the community Determines practices that keep the community healthy 1. Education - provide information to medical practitioners and the public on which practices keep the community healthy - examples: diabetes prevention, rabies prevention, rodent control, insect control 2. Publicity – inform the media of events threatening the health of the community - examples: chemical toxins, infectious microorganisms - demonstrate that infectious and toxic agents do not observe geographical or political boundaries Natural disasters – hurricanes, floods, evacuations, water safety when spills occur Food safety – recalls of food due to microbial or chemical contamination Biodefense (formerly Bioterrorism) – events where suspicious substances were found Communicable outbreaks – Ebola, Severe Acute Respiratory Syndrome, West Nile Virus. Chikungunya Virus, Zika Virus 3. Policy makers - the President, Governors, Health Commissioners 4. Immunization Programs - work with Clinicians and Practitioners to immunize against communicable diseases - provide immunizations for travel outside the US 5. Epidemiological Investigations - determining the cause of a community sickness ex. food borne outbreaks, contaminated water supplies 6. Laboratory Analysis - epidemiologists depend upon rapid and accurate testing for determining the cause of a community sickness Established by the Department of Health and Human Services, Centers for Disease Control and Prevention (CDC) in accordance with a Presidential Decision Directive outlined national anti-terrorism policies and assigned specific missions to federal departments and agencies objective was to ensure an effective laboratory response to bioterrorism by helping to improve the nation's public health laboratory infrastructure Involves laboratories on the national, state and local levels Sentinel Public Health Laboratories – recognize, rule out, refer o County public health laboratories Reference Public Health Laboratories – confirmatory testing o State public health laboratories National Public Health Laboratories – definitive characterization 1. National Level - Center for Disease Control and Prevention (CDC) National Public Health Laboratory - United States Army Medical Research Institute for Infectious Disease (USAMRIID) Military Public Health Laboratory - BS Level 4 laboratory facilities 2. State level - each state has a Public Health Department - New York State Wadsworth Center in Albany 3. County Level 62 counties in New York State 8 counties provide laboratory service There are 3 public health laboratories in New York State that are part of the LRN: Wadsworth Center Westchester County Public Health Laboratory Erie County Public Health Laboratory (ECPHL) ECPHL is registered with the LRN ECPHL serves 17 counties of Western New York and the Finger Lakes regions Responds to potential public health threats, including bioterrorism Aim of Clinical Laboratory - patient with symptoms diagnostic testing - treatment and discharge of patient - offer testing services on 24/7 schedule Aim of Public Health Laboratory - diseases affecting populations - screening/surveillance testing -treatment as part of prevention/control of disease - offer services during defined hours of operation Look at disease affecting a population not just an individual Surveillance and prevention means working with field personnel to coordinate information Deals with environmental issues Three laboratories Main laboratory – majority of laboratory testing • located in Buffalo Two STD Clinic laboratories: Buffalo Niagara Falls To provide proficient, cost-effective laboratory services educational programs method evaluations epidemiological support scientific study resources to health care services, laboratories, environmental sciences, government and private communities of Western New York Three major divisions: Environmental Clinical Biodefense 1. Environmental testing - test everything from A-Z a. recreational water testing - E. coli and enterococci, microcystin, Haloacetic acids (HAA) ex. beach closings b. potable water testing - well water, tap water, irrigation water - total coliform, E.coli, lead 1. Environmental testing (con’t) c. distilled water - cadmium, chromium, copper, iron, lead, nickel, zinc d. dialysis water 1. inorganics: fluoride, sulfate, nitrate 2. trace metals: aluminum antimony, arsenic, barium, beryllium, cadmium, chromium, copper, lead, manganese, mercury, nickel, selenium, silver, thallium, zinc 1. Environmental testing (con’t) e. soil, paint chips - heavy metal analysis ex. lead testing f. Organic chemicals - volatile organic compounds (VOCs) - semi-volatile compounds (pesticides, polychlorinated biphenyls [PCB], oil, grease, total petroleum hydrocarbons [TPH]) 1. Environmental testing (con’t) g. inorganic chemicals 1. physical description - color, pH, turbidity, total solids, dissolved solids, suspended solids, settleable solids 2. chemical testing - ammonia, calcium, chloride, cyanide, fluoride, nitrate, nitrite, orthophosphate, sulfate 1. Environmental testing (con’t) g. Disinfection byproducts - haloacetic acid (HAA), trihalomethanes, chlorate, chlorite, bromate, bromite f. Food and restaurant testing - coliform count, E.coli, enterococcus, endotoxin, biological oxygen demand (BOD), chemical oxygen demand (COD) 2. Clinical Testing a. Microbiology - Enteric pathogens in food and fecal outbreaks, urine cultures, Group B streptococcus, Neisseria gonorrhoeae b. Clinical Chemistry - liver function tests (for TB Clinic) c. Immunology - hepatitis, HIV, Herpes simplex, syphilis d. nucleic acid amplification (NAAT) – chlamydia, gonorrhea, Trichomonas vaginalis 2. Clinical testing (con’t) e. Respiratory infectious agents Influenza A&B, Bordetella pertussis, parapertussis, holmesii, Zika, Dengue, Chikungunya f. STD Clinics - gram stains, wet preparations, rapid HIV, pregnancy testing Satellite laboratories located in STD clinics Perform gram stains and wet mounts immediately for prompt treatment of patient and sexual contacts Gram stains screened for sexually transmitted organisms Wet mounts performed on vaginal swabs to screen for Trichomonas vaginalis, yeast and clue cells Immediate treatment to reduce non-compliance Pregnancy testing performed if antimicrobial drugs would be contraindicated in pregnancy 3. Biodefense testing performed in a BS Level 3 facility a. agents of bioterrorism - Bacillus anthracis, Yersinnia pestis, Francisella, Brucella, ricin b. Respiratory viral agents, viral hemorrhagic fever agents c. Air monitoring of events ex. sports events In New York State, any reporting on patient samples must be performed by a licensed Clinical Laboratory Technologist or Laboratory Technician Clinical laboratory practitioners also work in other areas of a public health laboratory A scientist with a degree in biology, chemistry, environmental science or similar degree may work in the environmental or biodefense sections but not in the clinical section Many employment opportunities for clinical laboratory Most testing in a PHL is performed during set business hours Generally PHL staff work Monday-Friday Occasional weekend or evening work Often work involves interactions with various practitioners and agencies Salary and benefits vary among laboratories Public health refers to any sickness that affects a community Components of PH include: education, publicity, policy makes, immunization programs, epidemiologic investigations, laboratory analysis Laboratory Response Network involves agencies that protect the public against bioterrorism The clinical laboratory detects illness within an individual; the public health laboratory detects community illness The ECPHL offers testing in 3 areas: environmental, clinical and biodefense Satellite laboratories in STD clinics provide immediate results for timely treatment PHL employ licensed Clinical Laboratory Technologist and Clinical Technicians www.emergency.cdc.gov/lrn/index/asp www.erie.gov/health/services/public_health_lab.asp
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