From: Aldose Reductase Inhibition Prevents Endotoxin-Induced Uveitis in Rats
Invest. Ophthalmol. Vis. Sci.. 2007;48(10):4634-4642. doi:10.1167/iovs.07-0485
Figure Legend:
Inhibition of AR prevented NO and PGE2 secretion in EIU. (AI, BI) NO and PGE2 levels in the AqH collected 6 and 24
hours after LPS injection were measured by ELISA. Data are expressed as the mean ± SD (n = 4), #P < 0.001 vs. the
control group and *P < 0.01 vs. the 24-hour EIU group. (AII, BII) Serial sections of paraformaldehyde-fixed rats’ eyes
were immunostained with antibodies against iNOS (AII) and COX-2 (BII) and observed by bright-field microscope. A
representative image is shown (n = 4). AqH, aqueous humor; C, cornea; CB, ciliary body; I, iris; V, vitreous; R, retina.
Magnification, ×200.
Date of download: 7/31/2017
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