THERAPEUTICS 3:
ANTIBIOTICS TUTORING
By Alaina Darby
GRAM POSITIVE AND GRAM
NEGATIVE PATHOGENS
Swanson’s Section
THE CULTURED BACTERIA IS PURPLE AND
GROWS BETTER WITHOUT OXYGEN. WHAT
IS IT?
a.
Gram positive, aerotolerant
b.
Gram positive, microaerophilic
c.
Gram negative, obligate anaerobe
d.
Gram negative, facultative anaerobe
WHICH OF THE FOLLOWING DOES NOT
DESCRIBE A GRAM POSITIVE ORGANISM?
a.
Inner cytoplasmic membrane
b.
LPS in outer membrane
c.
Vulnerable to lysozyme
d.
Low lipid content
WHERE ARE THE PENICILLIN BINDING PROTEINS
LOCATED?
a.
Outer membrane of gram positive organisms
b.
Outer membrane of gram negative organisms
c.
Cell wall of gram positive organisms
d.
Cytoplasmic membrane of gram positive organisms
JR HAS SEPTIC ARTHRITIS. WHICH OF THE FOLLOWING
PATHOGENS IS THE MOST LIKELY CAUSE?
a.
Staph aureus
b.
Staph epidermidis
c.
Strep viridans
d.
Strep pyrogenes
PBP2A MAKES S. AUREUS RESISTANT TO WHICH
OF THE FOLLOWING MEDICATIONS?
a.
Penicillin
b.
Amoxicillin
c.
Nafcillin
d.
Vancomycin
JD HAS A S. AUREUS INFECTION. IT IS
COMMUNITY ACQUIRED. WHICH OF THE
FOLLOWING WOULD BE THE FIRST CHOICE?
a.
Dicloxacillin
b.
Methicillin
c.
Ceftaroline
d.
Vancomycin
IT TURNS OUT THAT JD’S INFECTION IS
MRSA. WHAT IS NOT A SUITABLE OPTION?
a.
Vancomycin PO
b.
Linezolid PO
c.
Clindamycin PO
d.
Bactrim PO
THE CULTURE FROM VF’S BIOPSY HIS CELLULITIS COMES
BACK WITH GROWTH OF PURPLE CHAINS OF SPHERICAL
BACTERIA. THE BACTERIA EXHIBITS COMPLETE HEMOLYSIS.
WHAT IS THE LIKELY PATHOGEN?
a.
S. agalactiae
b.
S. pyrogenes
c.
S. viridans
d.
S. pneumoniae
THE CULTURE FROM VF’S BIOPSY HIS CELLULITIS COMES
BACK WITH GROWTH OF PURPLE CHAINS OF SPHERICAL
BACTERIA. THE BACTERIA EXHIBITS COMPLETE HEMOLYSIS.
HOW WOULD YOU TREAT HIM IF HE PREVIOUSLY HAD A
RASH FROM PCN EXPOSURE?
a.
Penicillin
b.
Erythromycin
c.
PCN + Clindamycin
d.
PCN + Gentamicin
FOR WHICH OF THE FOLLOWING IS S. PNEUMO
NOT THE MOST COMMON CAUSE?
a.
Meningitis
b.
Otitis media
c.
Endocarditis
d.
CAP
WHICH OF THE FOLLOWING WOULD BE
PREFERRED FOR TREATMENT OF MENINGITIS?
a.
Cefazolin
b.
Cefoxitin
c.
Ceftazidime
d.
Ceftriaxone
OK HAS AN ENTEROCOCCAL UTI. WHICH OF THE
FOLLOWING WOULD BE LEAST APPROPRIATE?
a.
Ampicillin
b.
Levofloxacin
c.
Vancomycin
d.
Nitrofurantoin
WHICH OF THE FOLLOWING WOULD BE A PO
OPTION FOR VRE?
a.
Linezolid
b.
Daptomycin
c.
Synercid
d.
Bactrim
WHICH OF THE FOLLOWING SHOULD NEVER BE
GIVEN IN A PERIPHERAL LINE?
a.
Linezolid
b.
Daptomycin
c.
Synercid
JR IS BEING TREATED FOR A CLOSTRIDIUM INFECTION. HE
PRESENTED WITH DIARRHEA. HIS MEDICATION INCLUDES
PCN AND A HYPERBARIC OXYGEN CHAMBER. WHICH
OF THE FOLLOWING DOES HE HAVE?
a.
Botulinum
b.
Difficile
c.
Perfringens
d.
Tetani
PR HAS FOOD POISONING. THE BACTERIA
CULTURES PURPLE AND IS AEROBIC. WHICH
OF THE FOLLOWING SHOULD BE
SUSPECTED?
a.
C. botulinium
b.
B. cereus
c.
L. monocytogenes
d.
E. coli
PR HAS FOOD POISONING. THE BACTERIA
CULTURES PURPLE AND IS AEROBIC. HOW
SHOULD IT BE TREATED?
a.
PCN
b.
Ampicillin
c.
Bactrim
d.
No treatment is necessary
PB HAS SEPTIC ARTHRITIS AND INITIAL
CULTURES ARE RED DIPLOCOCCI. HOW
SHOULD IT BE TREATED INITIALLY?
a.
Ceftriaxone
b.
Moxifloxacin
c.
Penicillin
d.
Ampicillin
WHICH OF THE FOLLOWING IS NOT A
COMMON GUT PATHOGEN?
a.
E. coli
b.
Klebsiella
c.
Pseudomonas
d.
Salmonella
E. COLI, PROTEUS, AND KLEBSIELLA ALL
COMMONLY CAUSE WHICH OF THE
FOLLOWING?
a.
Diarrhea
b.
Community acquired UTI
c.
Noscomial pneumonia
d.
Community acquired pneummonia
JH HAS BLOODY DIARRHEA WITH ELEVATED
WBC’S. WHAT WOULD BE THE MOST
APPROPRIATE TREATMENT?
a.
Ceftriaxone
b.
Ciprofloxacin
c.
Ceftolozane
d.
Bactrim
JH HAS BLOODY DIARRHEA WITH ELEVATED
WBC’S. WHAT WOULD BE THE MOST
APPROPRIATE TO ADD TO CEFTRIAXONE?
a.
Imipenem
b.
Amoxcillin
c.
Gentamicin
d.
Levofloxacin
KT HAS DUODENAL ULCERS. WHAT
BACTERIA SHOULD BE MOST SUSPECTED?
a.
Campylobacter
b.
Shigella
c.
H. pylori
d.
Salmonella
WHICH IS LEAST LIKELY TO CAUSE
BLOODY DIARRHEA?
a.
Campylobacter
b.
V. cholera
c.
Shigella
d.
E. coli
FR HAS A BURN WOULD THAT SMELLS
EERILY LIKE GRAPES. CULTURES SHOW REDCOLORED BACILLI. WHAT IS THE BEST
TREATMENT?
a.
Zosyn + gentamicin
b.
Zosyn + amikacin
c.
Zosyn + tobramycin
d.
Zosyn
REMEMBER THE “ABC”S OF H. FLU!

Amoxicillin/Azithromycin

Bactrim

Clarithromycin/Cephalosporins

Type B… blood, brain, bone
AH CHECKS INTO THE VA MEDICAL CENTER AND HAS
TO BE INTUBATED DUE TO PNEUMONIA. THE CULTURE IS
A G(-) ROD. HE ALSO HAD CONFUSION AND A
HEADACHE BEFORE HE WAS ADMITTED. HOW SHOULD
YOU TREAT HIM?
a.
Azithromycin + rifampin
b.
Ceftriaxone
c.
Bactrim
d.
Zosyn + gentamicin