Confidential
Astra Zen
Why !
Hydrogen Water
What is Hydrogen Water ?
Introduced on SBS program, ‘Living Economy’ on April 26, 2013.
http://netv.sbs.co.kr/player/netv_player.jsp?uccid=10002157841
Oxygen Free Radicals,
cause of aging and a variety of diseases
Hydrogen Water gets rid of Oxygen Free Radicals.
The Japanese has been interested in hydrogen
water for a long time.
Published more than 200 theses relevant to
the efficacy of hydrogen water.
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Studies on Efficacy of Hydrogen Water
Hydrogen-rich water gets rid of oxygen free radicals, cause of aging and a variety of diseases
Efficacy in the prevention and treatment of cancer and a variety of lifestyle-related diseases
• Diabetes
• Neurological disease
• Cancer
• Metabolic Syndrome
• muscular disease
• Eye disease
• Arteriosclerosis
• Liver disease
• Hearing impairment
• Hyperlipidemia
• Pancreas disease
• Radioprotective effect
• Myocardial infarction
• Kidney disease
• Skin care
• Cerebral infarction
• Respiratory disease
• Dental and gingival disease
• Obesity
• Organ transplant
• Allergy
• Dementia
• Heart disease
• Atopic disease
• Alzheimer's disease
• Large intestine disease
• Immunity
• Parkinson's disease
• Lung disease
• Bone disease
Anti-Aging Effects of H(H2O)m in Human Skin
: Department of Dermatology, Seoul National University College of Medicine, Seoul, Korea
Published on PLOS ONE, International online publication, in the April of 2013
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Example 1 : Effect in Skin Care
Journal of Photochemistry and Photobiology B : Biology, 2011.Oct. 20
Hydrogen-rich electrolyzed warm water represses wrinkle formation against UVA ray together with type-1
collagen production and oxidative-stress diminishment in fibroblast and cell-injury prevention in
keratinocytes
Kato S, Saitoh Y, Iwai K, Miwa N.
(Laboratory of Cell-Death Control BioTechnology, Faculty of Life and Environmental Sciences, Prefectural University of
Hiroshima, Nanatsuka 562, Shobara, Hiroshima 727-0023, Japan.)
Abstract
Hydrogen-rich electrolyzed warm water (HW) was prepared at 41°C and exhibited dissolved hydrogen (DH) of 1.13 ppm and
an oxidation-reduction potential (ORP) of -741 mV in contrast to below 0.01 ppm and+184 mV for regular warm water (RW).
Fibroblasts OUMS-36 and keratinocytes HaCaT were used to examine effects of HW against UVA-ray irradiation. Type-I
collagen was synthesized 1.85- to 2.03-fold more abundantly by HW application for 3-5 days than RW in OUMS-36
fibroblasts, and localized preferentially around the nuclei as shown by immunostain. HW application significantly prevented
cell death and DNA damages such as nuclear condensation and fragmentation in UVA-irradiated HaCaT keratinocytes as
estimated by WST-1 and Hoechst 33342 assays. HW significantly suppressed UVA-induced generation of intracellular
superoxide anion radicals in both the cell lines according to NBT assay. Wrinkle repression was clinically assessed using a
HW-bathing. Six Japanese subjects were enrolled in a trial of HW-bathing (DH, 0.2-0.4 ppm) every day for 3 months. HWbathing significantly improved wrinkle in four subjects on the back of neck on 90th day as compared to 0 day. Thus, HW may
serve as daily skin care to repress UVA-induced skin damages by ROS-scavenging and promotion of type-I collagen
synthesis in dermis.
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Example 2 : Effect in Diabetes
Nutrition Research, 28 (2008) p137 ~ 143
Supplementation of hydrogen-rich water improves lipid and glucose metabolism in patients with type 2
diabetes or impaired glucose tolerance.
Kajiyama S, Hasegawa G, Asano M, Hosoda H, Fukui M, Nakamura N, Kitawaki J, Imai S, Nakano K, Ohta M,
Adachi T, Obayashi H, Yoshikawa T.
(Kajiyama Clinic, Kyoto 615-0035, Japan.)
Abstract
Oxidative stress is recognized widely as being associated with various disorders including diabetes, hypertension, and
atherosclerosis. It is well established that hydrogen has a reducing action. We therefore investigated the effects of hydrogenrich water intake on lipid and glucose metabolism in patients with either type 2 diabetes mellitus (T2DM) or impaired glucose
tolerance (IGT). We performed a randomized, double-blind, placebo-controlled, crossover study in 30 patients with T2DM
controlled by diet and exercise therapy and 6 patients with IGT. The patients consumed either 900 mL/d of hydrogen-rich
pure water or 900 mL of placebo pure water for 8 weeks, with a 12-week washout period. Several biomarkers of oxidative
stress, insulin resistance, and glucose metabolism, assessed by an oral glucose tolerance test, were evaluated at baseline
and at 8 weeks. Intake of hydrogen-rich water was associated with significant decreases in the levels of modified low-density
lipoprotein (LDL) cholesterol (ie, modifications that increase the net negative charge of LDL), small dense LDL, and urinary 8isoprostanes by 15.5% (P < .01), 5.7% (P < .05), and 6.6% (P < .05), respectively. Hydrogen-rich water intake was also
associated with a trend of decreased serum concentrations of oxidized LDL and free fatty acids, and increased plasma levels
of adiponectin and extracellular-superoxide dismutase. In 4 of 6 patients with IGT, intake of hydrogen-rich water normalized
the oral glucose tolerance test. In conclusion, these results suggest that supplementation with hydrogen-rich water may have
a beneficial role in prevention of T2DM and insulin resistance.
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Why !
Astra Zen
No. 1 Technology
No. 1 Technology in the World
Generation of hydrogen-rich water over 1,000 ppb
within 3 minutes regardless of original water
3
minutes
1,000~1,200ppb
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Technology of Hydrogen-rich Water Generation
Hydrogen
Concentration
ORP
1,000 ~ 1.200 ppb
(1,000ppb = 1ppm)
(Oxidation Reduction
Potential)
(-) 350 ~ (-) 550mV
pH
Neutral (6.5~7.5)
Core Technology – Astra Cell
Hydrogen
Concentration
Astra Cell
Patent Registration
S. Korea, Japan, USA, China,
UK, France, Germany, Italy, Spain
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Hydrogen Concentration
[Japan Hydrogen Water Promotion
Association]
Hydrogen Concentration Test
Result
1,248 ppb
(November 18, 2013)
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Product introduction
Power Consumption
80 W
Dimension (W x H x D)
130x375x282 (Body) mm
Body Weight
3.8 Kg
Capacity
1,000cc
Generation Time
2 ~ 3 minutes
(According to amount of water)
Hydrogen Concentration
1,000ppb ~ 1,200ppb
Generation Type
Electrolysis
Cleaning
Automatic circulation cleaning
!! Astra Zen is superior to other products competing in the Japanese market. !!
ü 1,000 ~ 1,200 ppb of high hydrogen concentration
Competitor : 300 ~ 1,000ppb
ü Generation of hydrogen-rich water over 1,000 ppb within 3 minutes
ü Generation of hydrogen from all kinds of water is available.
Competitor : 5 ~ 10 minutes
Competitor : Limited kinds of water
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Key Features
Hygiene
ü Triple-cover structure to block the entry of particles and bacteria
ü Stainless tank which prevents scale and the growth of bacteria, is very easy to clean.
Easy
to Operate
ü All operations can be controlled by 4 buttons only.
ü Function to alert that the tray is filled with drainage water
ü Tray is removable easily.
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Key Features
Portable
Portable Bottle is provided.
[Holder for portable bottle]
ü Simple
Design
ü Compact
ü Modern
Cutting-edge
ü Cutting-edge MICOM and User-friendly Software
ü Real-time display on self-test and operating
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SPECIFICATION
Brand
Spec.
Astra Zen
Dimension
(W x H x D) mm
130 x 375 x 282
Hydrogen
Concentration
1,000~1,200 ppb
Generation Time
2 ~ 3 minutes
ORP
-350 ~ -550mV
pH
6.5 ~ 7.5 (Neutral)
Capacity
1,000 cc
ETC
Automatic circulation cleaning
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Astra Zen in Japan
Market Size
* Being sold at Rakuten, Yodobashi, Biccamera, Amazon
Source : Health industry Newspaper
on Nov. 16, 2013
• 2012 : 16.5 billions of Japanese Yen
• 2013 : Over 20 billions of Japanese Yen
Product registered with
Japan Hydrogen Water Promotion Association
• Going to Growth from Introduction
• Panasonic’s Market Entry
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Thank you.
HAEKEON CORPORATION
333 Worldcup Bukro 4gil 77 Mapo Seoul South Korea
Tel. 82 70 8679 2340 Fax. 82 32 624 1940 Mobile. 82 10 3208 4999
E-mail. [email protected]
Web- Site. www.haekeon.co.kr