CENTRAL REGION Integrated Systemic Biology Unit Pharmacogenomics Centre Universiti Teknologi MARA (UiTM) Offers qualitative and quantitative determination of molecular features for global and targeted metabolomics and proteomic study. • Services offered by Integrated Biosignature Transcriptomic Unit: • • Chemical/ molecular extraction / purification / quantification: Profiling and identification of metabolites from plants and cell extracts in search of drug targets. Clinical pharmacology (ADME / toxicology / bioavailability/ bioequivalence): Semi quantitations small molecules and proteins for systemic biology study including profiling of toxic metabolites responsible for ADR using metabolomics approach. CONTACT PERSON Biomarker identification/ characterisation/ selection: Disease markers identification and monitoring of markers for response to therapy. Comprehensive nonselective and targeted analysis of all metabolites and proteins of a biological system (human, cell lines, animals) for identification and quantification. The metabolites and proteins are indicative of disease, therapeutic progression, or adverse drug reactions. Equipment / Facilities Available: • Liquid Chromatography Mass Spectrometry Assoc Prof Dr Teh Lay Kek Prof Dr Mohd Zaki Salleh Head Integrated Systemic Biology Unit Pharmacogenomics Centre Level 7, Building FF3 Faculty of Pharmacy Puncak Alam Campus 42300 Puncak Alam Selangor Tel : +6 03-3258 4661 Fax : +6 03-3258 4602 Email : [email protected] [email protected] Head Pharmacogenomics Centre Level 7, Building FF3 Universiti Teknologi MARA Faculty of Pharmacy Puncak Alam Campus 42300 Puncak Alam Selangor Tel Fax Email : +6 03-3258 4685 : +6 03-3258 4602 : [email protected] [email protected]
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