Brainstorming session: what interest can
there be in thinking about a possible new
HeC 2 project to follow-up the current
one, after its end by 2009
Edwin Morley-Fletcher,
Lynkeus
HeC PMT Meeting Tallinn 10 July 2008
ICT Work Programme
Structure:
• A limited set of Challenges
• Each of which is addressed through a limited
set of Objectives
• That form the basis of Calls for Proposals
• A total of 25 Objectives expressed within 7
Challenges
2
Health-e-Child, July 10th, 2008
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Focus on application-led challenges
• New technology-based systems, products and
services that provide step-changes in the
capabilities of the resulting application solution
• Evolution and interoperability of service platforms
• Scale and complexity in dynamic, distributed
heterogeneous environments, including open
service networks
• Advanced user-driven open innovation
methodologies integrating all relevant actors in a
flexible service and technology innovation
ecosystem
• Standardisation, recognised as important research
outcome and as visible way to promote research
results
3
Health-e-Child, July 10th, 2008
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Focus on ICT tools for sustainable and
personalised healthcare
• Ensuring delivery of quality healthcare at affordable
costs contributing to greater efficiency of health
systems
• Saving lives and resources by focusing on:
• prevention and prediction of diseases
• improved patient safety by optimising medical
interventions and preventing errors
• Developing new ICT-based environments for
biomedical research and predictive medicine
• that push the boundaries of technologies like grid
computing, modelling and simulation
4
Health-e-Child, July 10th, 2008
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Challenge 5: Towards sustainable and
personalised healthcare
• Looking for changes in the way healthcare is
delivered and the way medical knowledge is
managed and transferred to clinical practice
• Recent capabilities of modelling, simulation
and biomedical imaging, combined with the
latest knowledge about diseases, give rise to a
new generation of predictive medicine
• In this challenge, support will go to highly
interdisciplinary research
5
Health-e-Child, July 10th, 2008
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Two Objectives within the ICT Work
Programme 2009-10
• Objective ICT for Patient Safety
(within Call 4)
• Objective Virtual Physiological Human
(within Call 6)
6
Health-e-Child, July 10th, 2008
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Objective ICT for Patient Safety
b) ICT for integration of clinical research and clinical care
• Seamless, secure and consistent integration of clinical care information
in electronic health records (EHR) with information in clinical research
information systems
• Research focusing on areas improving semantic interoperability
between EHR and clinical research systems
• Definition and validation of core data set enabling scalable and
standardised link between clinical research systems and EHR
repositories
• Leading to well defined use cases with high potential for improving
patient safety
Possible budget distribution for a) and b): IP/STREP – around 30 M€
The objective is to support at least 1 IP under a) and at least 1 IP under
b) in addition to STREPs
7
Health-e-Child, July 10th, 2008
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Objective Virtual Physiological Human (1)
a) Development of patient-specific computer based
models and simulation of the physiology of human
organs and pathologies
• The models should be multiscale by integrating relevant aspects
of anatomy and physiology across different levels (from
molecular and cellular to tissue and organ levels)
• The emphasis should be on the integration of existing models
rather than on development of new models.
• The use and benefits of the models must be demonstrated for a
specific clinical need covering prediction of disease and/or early
diagnosis
• Any organ or pathology could be targeted as clinical application.
• If an initial phase of basic clinical research or data collection is
needed it will represent less than 25% of the total effort
8
Health-e-Child, July 10th, 2008
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Objective Virtual Physiological Human (2)
b) Development of ICT tools, services and specialised infrastructure
for the bio-medical researchers
to support at least two of the following three activities:
• i) to share data and knowledge needed for a new integrative research
approach in medicine (biomedical informatics),
• ii) to share or jointly develop multiscale models and simulators,
• iii) to create collaborative environments supporting this highly multidisciplinary
field.
•
•
•
•
9
When necessary, computing power and data management could be
sought through access to existing advanced grid
New tools, services and applications will also be evaluated on their
effectiveness and their ability to interface with existing medical research
infrastructures. Their targeted services will facilitate the clinical use of
computer based organ and disease models as well as biomedical data
These tools and services will complement and be compatible with
existing methods and standards (terminologies, ontologies, mark-up
languages)
International Cooperation in this field is encouraged.
Health-e-Child, July 10th, 2008
[email protected]
Objective Virtual Physiological Human (3)
• Possible budget distribution for a) and b)
IP/STREP – around 60 M€
• with more than 50% to IPs
• with a minimum of 3 IPs including at least one
under a) and at least one under b)
10
Health-e-Child, July 10th, 2008
[email protected]
HeC’s new possible goals
Establishing itself as the paediatric platform by:
• Broadening and deepening its clinical
scope
• Multiplying the number of paediatric
hospitals being active members of HeC
• Increasing its overall technological
integration by moving from being a SOA to
becoming a SOKU
11
Health-e-Child, July 10th, 2008
[email protected]
Specifically with reference to call 4
Establishing HeC as the paediatric paltform also
by:
• Assuring advanced risk-management and
improved patient safety by checking internal
hospital communication, appropriateness of
procedures and prescriptions according to clinical
indicators, and by making use of specific DSS
tools
• Anticipating the development of EHR within paediatric
hospitals by establishing common standards of
electronic data input and data retrieval on HeC’s Grid
platform
12
Health-e-Child, July 10th, 2008
[email protected]
What does SOKU mean?
• The evolution of Grid from a tool to solve computeand data-intensive problems towards a generalpurpose infrastructure enabling complex business
processes and work flows across virtual
organisations spanning multiple administrative
domains
• Three complementary dimensions:
• an end-user perspective (simplicity of access to and use
of Grid technologies)
• an architectural perspective (where the Grid is seen as a
large evolutionary system made of billions of
interconnected nodes of any type)
• a software perspective (a fully programmable and
customisable Grid)
13
Health-e-Child, July 10th, 2008
[email protected]
David Manset’s SOKU flower
14
Health-e-Child, July 10th, 2008
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Getting ready for Call 4?
Advantages of:
• Submitting a proposal for Call 4 (Patient safety),
keeping open the default solution of submitting
also a proposal for Call 6 (Virtual Physiological
Human) a year later, if unsuccessful in the first
attempt
• Starting in time a complex decision-making
process within HeC, and getting appropriate
feed-back from the ICT for Health Unit of the EC,
which seems willing to support HeC’s further
development
15
Health-e-Child, July 10th, 2008
[email protected]
When to communicate with ICT for
Health Unit?
• Need to express appropriate interests in the
specific definition of Call 4
• Tight timing:
• Any expression of interest should be signaled in the
coming weeks
• The Call is due to be issued by the Fall of 2008
• The deadline for submission will be in Spring 2009
April
• If successful, funding could then start in 2010
16
Health-e-Child, July 10th, 2008
[email protected]
What specific clinical and technological
developments should we focus on?
• Giacomo
• Martin
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Health-e-Child, July 10th, 2008
[email protected]