Supplemental Digital Content 2 Kaplan Meier curves for single sum values of the prognostic score (raw data) Single sum values of Prognostic score (raw data) and survival. sum value 3 4 5 6 7 8 9 patients (n) 43 33 50 76 84 72 70 mean OS (months) not reached not reached 91 61 34 14 12 95% CI . . 21-101 11-57 9-19 9-16 For the assessment of the prognostic groups, first survival analysis was performed for all sum scores separately. The results of this analysis showed that there were apparently three groups of patients with comparable clinical outcomes (group A: 3-4 points; group B: 5-7 points; group C: 8-9 points). In a second step, we used this division for further evaluation of the PRSC as it is described in the main manuscript.
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