Transport of Oxygen
• 3% in dissolved form i. e. dissolved in plasma.
• 97% bound to Haemoglobin
O2 Transport as dissolved in plasma
• At Arterial Po2 = 0.29 ml of O2 dissolved in 100 ml of
blood
• At Venous Po2 = 0.12 ml of O2 dissolved in 100 ml of
blood
0.17 ml of O2 is carried in dissolved state to tissue by each
100 ml of blood
O2 transport as bound to Hb
1gm Hb can carry = 1.39 ml of O2.
But due to impurities like met Hb
1gm Hb carries 1.34 ml of O2
15 gms will carry 1.34 x 15 = 20.10 ml of O2
This happens at or more than 250 mmHg when
Hb is 100% saturated.
At arterial PO2 only 97% of Hb is saturated
O2 transport as bound to Hb
At arterial PO2 19.4 ml of O2 is bound to Hb.
At venous PO2 14.4 ml of O2 is bound to Hb.
5 ml of O2 is transported as bound form from
lungs to tissues by each 100 ml of blood.
O2 Hb dissociation curve
Factors affecting O2 Hb dissociation curve
1.
2.
3.
4.
5.
6.
7.
8.
CO2--------- Bohr effect
Hydrogen Ion
Temperature
BPG( Bisphosphoglycerate )
Electrolytes
Met Hb
HbF
Hormones