Cell Signaling (2)
Supplemental Instruction
Iowa State University
Leader:
Course:
Instructor:
Date:
Caleb I.
BIOL 212
Dr. Kukday
3/6/2017
1.) Vocabulary Review- Match the Terms & Definitions:
a. Receptors located inside the cell
i.
Glucocorticoid ___
b. The protected tip of grass or a
ii.
Apoptosis ____
stem of a plant
iii. Intracellular Receptors _____
c. A molecule that absorbs
iv.
Phototropic Response ____
specific wavelengths of light
v.
Coleoptile ____
d. Programmed death of a cell
vi.
Pigment ______
e. Pigments involved in the
specific light response
vii.
Phototropins ______
f. A steroid hormone made of 4
6-carbon rings
g. A change in an organism to
react specifically toward light
2.) Can you predict the effect of mutations in proteins that are part of cell signaling
pathways? ----- Discuss in your groups examples of how mutations could effect cell
signaling pathways: Think of examples from class, and talk about how cells could be
affected by mutations. (Look at both cell signaling powerpoints).
3.) Can you identify potential therapeutic strategies for compensating in overactive or
underactive signaling?
i.
If a cell is overactive we could:
ii.
If a cell is underactive we could:
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
4.) Can you summarize the steps in the process of signal transduction in plants? ----- List the
3 main steps below then list what occurs in each of those steps:
i.
ii.
iii.
5.) Can you analyze data from key experiments that led to the discovery of auxin as the
hormone signal in the phototropic response? -----
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
Dr. Kukday’s “Can You?” Questions: (Italicized steps were discussed in cell signaling 1)
Cell Signaling:
1.) Can you connect the 4 steps in cell signaling to each of the examples provided? For
example, what part of the apoptosis pathway can be considered signal processing?
2.) Can you identify the types of receptors (cell surface and intracellular) that a cell uses to
receive signals from their environment?
3.) Can you describe the role of cAMP in signal transduction? Are there examples of other
molecules that perform a similar role?
4.) Can you illustrate key steps in the signaling pathway for EGF and epinephrine? How is
the signal transmitted in both cases? What is the final response for each pathway? What
are the differences between the two pathways?
5.) Can you identify steps in the apoptosis pathway?
6.) Can you predict the effect of mutations in proteins that are part of cell signaling
pathways?
7.) Can you identify potential therapeutic strategies for compensating in overactive or
underactive signaling?
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu
Plant Cell Signaling:
1.) Can you summarize the steps in the process of signal transduction in plants?
2.) Can you identify two pathways that are used to transduce signals inside plant cells?
3.) Can you identify responses that plant cells can launch after receiving signals from the
outside environment?
4.) Can you analyze data from the experiment that led to the discovery of the mechanism of
PHOT1, the phototropic receptor protein?
5.) Can you analyze data from key experiments that led to the discovery of auxin as the
hormone signal in the phototropic response?
1060 Hixson-Lied Student Success Center  515-294-6624  [email protected]  http://www.si.iastate.edu