Chapter 7: The Nervous System HUMAN ANATOMY AND PHYSIOLOGY I. II. Introduction A. The Nervous System B. General Functions 1. Sensory Input 2. Integration 3. Motor Output Organization of the Nervous System CENTRAL NERVOUS SYSTEM (CNS) Structure Function Sensory (Afferent) Division PERIPHERAL NERVOUS SYSTEM (PNS) Motor (Efferent) Division Sensory (Afferent) Division AUTONOMIC NERVOUS SYSTEM SYMPATHETIC NERVOUS SYSTEM Motor (Efferent) Division SOMATIC NERVOUS SYSTEM PARASYMPATHETIC NERVOUS SYSTEM Chapter 7: The Nervous System HUMAN ANATOMY AND PHYSIOLOGY III. Histology of Nervous Tissue A. Neuroglia/ Glial Cells 1. Neuroglia in the CNS a. Astrocytes [green] b. Microglia [yellow] c. Ependymal Cells [orange] d. Oligodendrocytes [purple] 2. Neuroglia in the PNS a. Satellite Cells b. Schwann Cells B. Neurons (Nerve Cells) 1. Special Characteristics a. Excitable b. Extreme Longevity c. Amitotic d. High Metabolic Rate Chapter 7: The Nervous System HUMAN ANATOMY AND PHYSIOLOGY 2. Structure a. Cell Body/Soma [yellow] b. Dendrites [green] c. Axon [blue] d. Axon Terminals [red] e. Myelin Sheath [purple] f. Nodes of Ranvier [label} Homeostatic Imbalance: What is multiple sclerosis (MS)? Identify its causes and symptoms. ________________________________ ________________________________ ________________________________ ________________________________ ________________________________ ________________________________ ________________________________ ________________________________ ________________________________ ________________________________ ________________________________ 3. Functional Classification of Neurons a. Sensory (Afferent) Neuron ________________________________ ________________________ b. Motor (Efferent) Neuron c. Interneurons (Association Neurons) Chapter 7: The Nervous System HUMAN ANATOMY AND PHYSIOLOGY IV. Neurophysiology A. Membrane Potential Membrane potential is the difference in charge (measured in millivolts) between the ______________ ___________________________________________________________________________________. V. Resting Membrane Potential A. Description 1. Concentration Gradient a. b. 2. VI. Polarized Membrane Potentials That Act as Signals A. Changes in Membrane Potential Neurons use changes in their ____________________________ as communication signals for receiving, integrating, and sending information. Changes in membrane potential are caused by three events: 1. Depolarization 2. Repolarization 3. Hyperpolarization Chapter 7: The Nervous System HUMAN ANATOMY AND PHYSIOLOGY B. Action Potentials 1. Definition a. Generation of an Action Potential b. Threshold c. Role of the Sodium- Potassium Pump i. ii. d. All – or – None Phenomenon e. Refractory Period Chapter 7: The Nervous System HUMAN ANATOMY AND PHYSIOLOGY f. Saltatory Conduction i. ii. Homeostatic Imbalance: Local anesthetics, like those used by your dentist, act by blocking Na + channels. How exactly do these anesthetics prevent you from feeling pain? ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ___________________________________________________________________ ______ VII. The Synapse The operation of the nervous system depends on the flow of information through chains of neurons functionally connected by ____________________. A. Definition B. Components 1. Presynaptic Neuron 2. Postsynaptic Neuron Chapter 7: The Nervous System HUMAN ANATOMY AND PHYSIOLOGY C. 3. Synaptic Cleft 4. Synaptic Vesicles Synaptic Transmission When a __________________________________ reaches the ____________________________, it sets into motion a chain of events that triggers ____________________________________________________. 1. Steps i. Ca2+ channels open in the presynaptic axon terminal. ii. Neurotransmitter is released. iii. Neurotransmitter binds to receptors on the postsynaptic neuron. iv. Ion channels open in the postsynaptic membrane. v. Neurotransmitter effects are terminated. Chapter 7: The Nervous System HUMAN ANATOMY AND PHYSIOLOGY VIII. Reflexes A. Definition 1. Receptor 2. Sensory Neuron 3. Integration Center 4. Motor Neuron 5. Effector
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