IGA
Istituto di Genomica Applicata
Institute of Applied Genomics
Scientific & Technological Park, Udine, Italy
at the roots
of diversity
Legal information
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Research Institute (ONLUS)
funded on April 13th, 2006
legally recognised by FVG Regional Adiministration on August 4th, 2008
Mission
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understand the genetic variation underlying the phenotypic diversity
develop algorithms for the analysis of biological systems
promote the scientific culture and the advancement of the society
promote the technological innovation in agro-food
Research activity
The mission is targeted by multidisciplinary approaches bridging genetics,
biochemistry, cell biology and bioinformatics that serve to:
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analyse structural and functional features of genomes
study evolutionary dynamics of genomes and population genetics
link genetic diversity with phenotypic variation
discover the molecular basis of complex traits
describe, simulate and predict biological processes through algorithms and
bioinformatics tools
• characterise, protect and exploit natural resources relevant to agriculture, food and
non-food industry
• promote innovation by transferring the results of research to the industry
• disseminate the scientific culture
Fields of Research
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strctural & functional genomics (genome sequencing and
annotation ...)
bioinformatics (development of algorithms and tools for the
management of genomic databases and the interpretation of
functional DNA motifs)
assisted breeding (development of breeding programs in food
and non-food chains)
molecolare diagnostic (genotyping platforms, forensic
fingerprinting , comparative genomics and transcriptomics...)
Core facilities
DNA sequencing core
• 4 ABI Prism 3730xl 96 capillary Sanger sequencers (5 Mb/giorno)
• 2 NG sequencers Illumina/Solexa GALII/ GALIIx (50 Gb/run)
• 1 NG sequencer Illumina/Solexa HiSeq2000 (200 Gb/run)
• 2 robots Beckmann, 9 PCRs ...
Centre of computational biology
• bar-coded pipeline and integrated LIMS for lab data management
• 64 bit cluster, 180 CPU-cores, 16 with parallel access at 128 GB RAM, 650
Gb RAM computational core
• 70 TB data storage
• proprietary software for data management, analysis and interpretation
Personnel
Staff (17 people)
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Michele Morgante, molecular geneticist, CEO of IGA
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Federica Cattonaro, molecular biologist, CEO of IGA_TS
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Gabriele Di Gaspero, plant molecular geneticist
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Alessandro Gervaso, systems administrator
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Eleonora Di Centa, molecular biologist
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Erica Ietri, administration
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Irena Jurman, molecular biologist
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Moira Livon, molecular biologist
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Federica Magni, molecular biologist
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Fabio Marroni, molecular biologist
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Elena Misdariis, administration
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Felice Nicoletta, chemist
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Alberto Policriti, bioinformatician
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Simone Scalabrin, bioinformatician
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Alberto Stefan, molecular biologist
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Raffaele Testolin, plant geneticist
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Daniele Trebbi, plant geneticist
Visiting scientists (3 people)
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Alberto Casagrande, University of Trieste, bioinformatician
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Rajora Om P, University of New Brunswick, forest geneticist
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Sugavanam Swaminathan, Univ. of Hyderabad, India, bioinformatician
PhD students, Post-doc (7 people)
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Dario Copetti, molecular biologist
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Cristian Del Fabbro, bioinformatician
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Stefania Giacomello, molecular biologist
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Sara Pinosio, bioinformatician
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Alessandro Spadotto, molecular biologist
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Vera Vendramin, plant molecular geneticist
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Francesco Viezzi, engineer
Projects
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VIGNA/VIGNE. Grape genome sequencing project (MiPAF with Genoscope 2006-2010)
Grape. Development of new grapevine varieties (FVG Region, 2007-2009)
Grape. Genotyping grapevine varieties and clones (FVG winemakers, 2008-)
Grape. Rapid analysis of secondary metabolite profiles (FVG Region, 2008-2010)
Coffee. Quality-controlling genes (Illy Co, 2008)
Barley. BAC end sequencing (IPK, Gatersleben, 2008-)
Wheat. Marker-assisted breeding (Barilla SpA, 2008-)
Wheat. Physical map of 4 chromosomes (EU Triticeae, 2008-)
Wheat. Physical map of chromosome 5 (MiPAF, 2009-)
Poplar. Energy poplar: gene mining (EU Energy Poplar, 2008-)
Peach. Peach genome sequencing project (MiPAF-Drupomics with JGI-USA, 2009-)
Citrus. Clementine genome sequencing (MiPAF Citromics with JGI-USA, 2009-)
Bees. Studies on CCD (Colony Collapse Disease) (MiPAF , 2009-)
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… other projects on plants, animals, fishes, and microorganisms under negotiation …
Services
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DNA and RNA sequencing and re-sequencing
genetic and physical maps
individual genotyping
production of genomic and cDNA libraries
DNA sequence alignment and querries on gene banks
analysis of DNA and set up of client-oriented software
data storage, backup and remote access to data
remote management of computing facilities
clients
• Universities and public/private Research Institutes
• Hospitals
• Private Companies (seed firms, agro-industries...)
Since September 2009
Services on demand are managed by
IGA - TECHNOLOGY SERVICES
Contacts
web site: www.appliedgenomics.org
e-mail: [email protected]
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Raffaele Testolin
Michele Morgante
Alberto Policriti
Gabriele Di Gaspero