endocrinology expected values and si unit conversion tables

ENDOCRINOLOGY EXPECTED VA LUES AND
S. I . UNIT CONVERSION TAB L ES
TABLE OF CON TE NTS
Introduction. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 2 – 3
Expected Values. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 4 – 73
References. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 74-77
S.I. Unit Conversion Table. . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 78-89
(E) = Esoterix Test Number
(L) = LabCorp Test Number
Esoterix is a wholly owned subsidiary of LabCorp where its Endocrine Sciences laboratory
operates as a Center of Excellence for specialized endocrinology. Endocrine Sciences' testing can
be accessed directly from Esoterix or through LabCorp and any of its regional facilities.
1
E X P E C T E D VA LU E S
I N T R O D U CT I O N
I N T RODUCT I ON
It is essential that a clinical laboratory establish reference ranges appropriate for its own methods.
The practice of using normal values obtained from the literature, or from other laboratories may
often be misleading. Confusion over test results often occurs because significant variations exist
in individual patient values and normal ranges reported by different clinical laboratories.This
variability is likely the result of dissimilar standard preparations, assay reagents, sample purification
procedures or other methodological factors.
As a specialized laboratory, Endocrine Sciences has long recognized the need for comprehensive
normal values for hormone tests. In response to this need, we have maintained an active program
to determine hormone levels in healthy individuals at all ages and over a broad range of
physiologic conditions.The value of this information is readily apparent to physicians who because
of the nature of endocrine disease, tend to rely heavily on laboratory results for diagnosis.
Diagnostic problems in pediatric endocrinology are further complicated by dramatic changes
in hormone levels which occur during the neonatal and prepubertal periods, at adrenarche,
and during pubertal development. Comprehensive normal values are indispensable to the
assessment of hormonal dysfunction in children. Since its founding in 1972, we have maintained
a continuous program to obtain normal ranges in children.
2
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Through collaborative studies conducted with pediatricians, hospitals and university research
centers, we have obtained comprehensive pediatric normals for the majority of our tests.
The information we have accumulated over the past several years is summarized in this section
to facilitate the interpretation of endocrine test results on pediatric patients.We would like to
express our gratitude to the many clinicians and researchers who have participated in our
program by generously contributing their time and patient samples.
The difficult nature of certain studies has made it impossible to collect all of the data through
our own program, necessitating that we obtain some values from research publications.
This was done only after extensive review and careful examination to insure that methods
demonstrated adequate specificity and that values were comparable to those determined at
Endocrine Sciences. In the future, it will be necessary to collect data in a few areas where we
were previously unsuccessful. Also, as new tests become available, we will need to establish
normal values for them as well.We cordially invite interested physicians to join us in this
continuing project.
(E) Esoterix Test Number
(L) LabCorp Test Number
3
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
A ci d L a b i l e S u b u n i t ( A LS )
5 0 00 1 2 (E )
BLOOD ASSAYS
5 00 1 20 (L )
R a n g e ( m g /L )
I N FA N TS
0 – 2 Months:
3 – 6 Months:
7 – 12 Months:
0.2 – 5.1
0.7 – 5.6
0.7 – 7.9
P R E P U B E RTA L
1 – 2 Years:
3 – 4 Years:
5 – 7 Years:
8 – 10 Years:
0.9 – 9.3
1.9 – 10
2.3 – 11
4.2 – 13
P U B E RTA L
11 – 13 Years:
14 – 18 Years:
5.6 – 16
5.6 – 16
A D U LT S
19 – 25 Years:
26 – 35 Years:
36 – 45 Years:
46 – 55 Years:
56 – 65 Years:
7.0 – 16
7.0 – 16
7.0 – 16
7.0 – 16
7.0 – 16
4
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Al d o ste ron e
BLOOD ASSAYS
5 00 0 14 (E)
5 00 4 67 (L )
SUPINE
( n g/ d L )
UP RI GH T
( n g/ d L )
P R E MAT U RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
5 – 635
19 – 141
not applicable
not applicable
FU LL-T ERM I NFA N TS
3 Days:
7 Days:
1 – 11 Months:
7 – 184
5 – 175
5 – 90
not applicable
not applicable
not applicable
C HILD RE N
12 – 23 Months:
24 Months – 9 Years:
10 – 14 Years:
7 – 54
3 – 35
2 – 22
not applicable
5 – 80
4 – 48
3 – 16
7 – 30
Ad Lib Sodium Intake
A D ULT S
Values are based on early morning samples from subjects on ad lib sodium intake.
Diurnal variations and values in pediatric patients on different sodium diets are
currently unavailable.
(E) Esoterix Test Number
(L) LabCorp Test Number
5
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Ad renocor ticot ropic Ho rmone (ACTH)
5 0 00 1 1 (E )
BLOOD ASSAYS
50 0 47 1 ( L )
C HI LDRE N:
ACTH levels in infants after one day, prepubertal and pubertal children are not significantly
different from adults.
A D U LT S
R A NG E
6 – 48 pg/mL
6
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
A l d o s t e r o n e, U r i n e ( I n c l u d e s C r e a t i n i n e )
5 00 0 18 (E)
50 0 76 0 ( L )
R A NG E
(u g / 2 4 h our s )
Ad Lib Sodium Intake
N EW B O R N
1 – 3 Days:
URINE ASSAYS
0.5 – 5
R A NG E
( u g /g c re a t i n i n e )
20 – 140
P R E P U B E RTAL C HIL DREN
4 – 10 Years:
1–8
4 – 22
Normal Sodium Intake
A D ULT S
1.5 – 20
3 – 19
Aldosterone excretion rates in infants and children on high and low sodium intake are not
available. Aldosterone excretion rates in newborns correlate highly with potassium: sodium
ratios but not with sodium intake.
(E) Esoterix Test Number
(L) LabCorp Test Number
7
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
A lpha Su bu nit
URINE ASSAYS
5 0 00 1 6 (E )
1 4 02 6 9 (L )
R A NG E ( ng / m L)
A D U LT
Males:
< 50 Years
>/= 50 Years
0.05 – 0.53
0.09 – 0.76
Females:
Premenopausal
Postmenopausal
0.04 – 0.38
0.09 – 1.23
A n d ro s t a n e d i o l G l u c u r o n i d e
5 0 00 2 6 (E )
BLOOD ASSAYS
5 0 08 8 1 (L )
R A NG E ( ng / d L )
P R E P U B E RTA L C HILDRE N
0-10 Years:
< 5 – 42
A D U LT S
Males:
Females*:
190 – 900
35 – 200
*Occasionally, normal females with no evidence of hirsutism may have levels well above the
normal range.
8
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
A n d r o s te n e d i o n e
BLOOD ASSAYS
5 0 00 3 0 (E )
5 0 01 5 2 (L )
R A NG E ( ng / d L )
R E MAT UR E IN FA NTS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
92 – 892
80 – 446
FU LL–TE RM I NFA N TS
1 – 7 Days:
20 – 290
Levels decrease rapidly to a range of 18 – 80 ng/dL after one week.
1 – 11 Months:
6 – 68
Androstenedione gradually decreases during the first six months to prepubertal levels.
P R E P U B E RTA L C HILDRE N
1 – 10 Years:
8 – 50
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(ng/dL)
MEAN
(ng/dL)
TANNER
STAGE
FEMALE
AGE
(years)
RANGE
(ng/dL)
MEAN
(ng/dL)
1
2
3
4
5
8 – 50
31 – 65
50 – 100
48 – 140
65 – 210
24
45
67
82
105
1
2
3
4
5
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
8 – 50
42 – 100
80 – 190
77 – 225
80 – 240
24
65
123
131
160
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
A D U LT S
18 – 40 Years:
Postmenopausal:
(E) Esoterix Test Number
R A NG E ( ng / d L )
MALE
75 – 205
(L) LabCorp Test Number
R A NG E ( ng / d L )
FEMALE (entire cycle)
60 – 245
30 – 120
9
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
A n t i d i u r e t ic H o r m o n e ( A D H ) * RUO *
5 0 00 3 5 (E )
BLOOD ASSAYS
5 0 08 4 6 (L )
R A N G E ( p g /m L )
A D U LT S
0.7 – 3.8
With normal serum osmolality
10
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
A n t i - M u l l e r i an Ho r m o ne ( A M H ) , S e r u m * RU O *
5 00 0 43 (E)
BLOOD ASSAYS
5 00 1 83 (L )
R A NG E ( ng / m L)
MA LE S
0 – 13 Days
14 Days -11 Months
12 Months – 6 Years
7 – 8 Years
Adult
15.5 – 48.7
39.1 – 91.1
48.0 – 83.2
33.8 – 60.2
3.0 – 5.4
F EM A LE S
0 – 8 Years
Adult
0.0 – 7.1
0.0 – 6.9
B o n e S p e c i f i c A l k a l i n e P h o s p h a t a s e, S e r u m
5 00 0 74 (E)
BLOOD ASSAYS
5 0 06 0 2 (L )
R A NG E
A D ULT S
20 – 79 Years:
(E) Esoterix Test Number
< 2 – 24 u/L
(L) LabCorp Test Number
11
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Ca l c i t o n i n
BLOOD ASSAYS
5 0 00 4 7 (E )
50 0 63 6 ( L )
R A N G E ( p g / mL )
MALES
0 – 150y
< 8.4
F EMAL ES
0 – 150y
< 5.0
Catecholamines, Fr ac tionated, P las m a
BLOOD ASSAYS
5 0 00 5 2 (E )
5 0 08 8 3 (L )
N OR E P IN E P HR IN E
R A N G E ( p g / mL )
E PI N E PHR I NE
R A N G E ( p g / mL )
N EW B O R N
1 – 7 Days:
200 – 420
20 – 130
C H IL DR EN
1 – 16 Years:
Basal:
150 – 400
20 – 115
A D U LT S
20 – 55 Years:
Basal:
Standing:
125 – 310
167 – 515
20 – 97
20 – 109
Values were obtained from samples collected under optimal, basal conditions whenever
possible. Catecholamine levels are elevated by many variables, including the stress of
venipuncture and by numerous pharmacological agents.
12
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Catecholamines, Fr ac tion ated, Ur ine
URINE ASSAYS
5 00 0 62 (E)
50 0 52 0 ( L )
R A N GE
( u g/ 2 4 h o u r s )
R A N GE
( ug / g c r e a t i n i n e )
I NFA N TS
< 1 Year:
Not Determined
37 – 195
C HILD RE N
1 – 10 Years:
Not Determined
24 – 140
O L DE R CHI L D R E N
AND ADU LT S
16 – 125
12 – 110
I NFA N TS
< 1 Year:
Not Determined
2 – 180
C HILD RE N
1 – 10 Years:
Not Determined
20 – 149
O L DE R CHI L D R E N
AND ADU LT S
3 – 38
9 – 25
N OR EP I N EP HRI N E
E P I N EP HRI N E
Pediatric values were determined on both random and 8 hour urine collections.
(E) Esoterix Test Number
(L) LabCorp Test Number
13
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Catecholamines, Tot al, Ur ine (Includes Cr e atinine)
5 0 00 6 0 (E )
5 0 04 7 3 (L )
R AN G E
(u g / 2 4 h our s )
R A NG E
( u g /g c re a t i n i n e )
I N FA N TS
< 1 Year:
Not Determined
34 – 286
C H IL DR EN
1 – 10 Years:
Not Determined
16 – 255
O L D E R C HI L DR E N
AND AD ULT S
30 – 118
22 – 115
14
URINE ASSAYS
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Co r ticoste roid Binding Globulin (CBG)
5 00 0 76 (E)
BLOOD ASSAYS
5 00 1 30 (L )
R A N G E (m g / d L)
N EW B O R N
0 – 3 Weeks:
1.6 – 2.5
I NFA N TS
4 Weeks – 11 Months:
2.2 – 8.3
F EM A LE S
12 Months – 8 Years
4.3 – 10
MA LE S
12 Months – 9 Years
4.3 – 10
O L DE R CHI L D R E N
AND ADU LT S
2.3 – 3.9
E S T R O GE N T H E R A P Y
AN D P R EG NA NCY
> 6.0
(E) Esoterix Test Number
(L) LabCorp Test Number
15
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Co r ticos te rone
BLOOD ASSAYS
5 0 00 8 4 (E )
5 0 01 35 (L )
R A N GE ( n g/ d L )
R A N GE ( n g/ d L )
P R E M ATU RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
235 – 1108
150 – 1700
N EW B O R N
1 – 7 Days:
30 Days – 11 Months:
70 – 850
80 – 1500
C H IL DR EN
1 – 16 Years:
8 : 0 0 a. m .
135 – 1860
4 :0 0 p. m .
70 – 620
A D U LT S
130 – 820
60 – 220
Co r tis ol, Fr ee, Ur ine (Includes Cr e atinine )
URINE ASSAYS
5 0 01 0 2 (E )
5 0 04 10 (L )
P R E P U B E RTA L C HI LD REN
R A NG E
( ug / 2 4 ho u r s )
3–9
R A NG E
( u g/g c r e a t i n i n e )
7 – 25
A D U LT MALE
11 – 84
7 – 45
A D U LT FEMA LE
10 – 34
9 – 32
P R E GN A NC Y
16 – 60
14 – 59
16
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Co r tis ol, S a li va
BLOOD ASSAYS
5 0 00 9 4 (E )
5 0 01 7 9 (L )
R A NG E ( u g / d L)
C HILDREN AND AD ULT S
8:00 a.m. 0.025 – 0.600
4:00 p.m. 0.010 – 0.200
Midnight <0.010 – 0.090
(E) Esoterix Test Number
(L) LabCorp Test Number
17
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Co r tis ol, S e rum
BLOOD ASSAYS
5 0 00 9 2 (E )
5 0 01 5 4 (L )
R A NG E ( u g / d L)
P R E M AT U RE I N FA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
1 – 11
2.5 – 9.1
FU LL–TE RM I NFA N TS
Day 3:
Day 7:
31 Days – 11 Months:
1.7 – 14
2.0 – 11
2.8 – 23
C H IL DR EN
12 Month – 15 Years:
8 :0 0 a . m .
3.0 – 21
4 : 0 0 p. m .
A D U LT S
8.0 – 19
4.0 – 11
18
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
C - Pe p t i d e , P l a s m a
BLOOD ASSAYS
5 0 01 0 4 (E )
5 0 06 4 2 (L )
R A N GE ( n g / m L )
C H IL DR EN
8:00 a.m. Fasting:
0.4 – 2.2
A D U LT S
8:00 a.m. Fasting:
2 Hours Post Prandial
(Sustacal):
2 Hours Post Glucose:
1.2 – 3.4
2.0 – 4.5
(E) Esoterix Test Number
(L) LabCorp Test Number
0.4 – 2.1
19
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
D e hy d r o e p i a n d r o s t e r o n e ( D H E A )
BLOOD ASSAYS
5 00 1 16 (E)
5 00 1 56 (L )
R A N G E (n g / d L)
P R E MAT U RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
236 – 3640
80 – 3150
FUL L–T ERM INFA N TS
3 Days:
8 – 30 Days:
31 Days – 5 Months:
6 – 11 Months:
65 – 1250
50 – 760
26 – 385
20 – 100
P R E P U B E RTAL C HIL DREN
12 Months – 5 Years:
20 – 130
6 – 7 Years:
20 – 275
8 – 10 Years:
31 – 345
Values begin to increase progressively at
about six years of age prior to any physical
evidence of puberty.
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(ng/dL)
MEAN
(ng/dL)
TANNER AGE
STAGE (years)
FEMALE
RANGE
(ng/dL)
MEAN
(ng/dL)
1
2
3
4
5
31 – 345
110 – 495
170 – 585
160 – 640
250 – 900
156
300
390
395
505
1
2
3
4
5
31 – 345
150 – 570
200 – 600
200 – 780
215 – 850
156
330
385
430
540
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
A D ULT S
20 – 50 Years:
20
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
160 – 800
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
D e hy d r o e p i a n d r o s t e r o n e S u l f a t e ( D H E A - S )
BLOOD ASSAYS
5 0 01 2 0 (E )
5 0 01 6 1 (L )
R A N G E (ug / d L )
P R E M ATU RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
FU LL–TE RM I NFA N TS
3 Days:
1 – 12 Months:
123 – 882
122 – 710
88 – 356
5 – 111 ug/dL by first month,
5 – 48 ug/dL by 6 months.
P R E P U B E RTAL
1 – 5 Years:
C H IL DR EN
6 – 7 Years:
8 – 10 Years:
P U B E RT Y
< 5 – 57
9 – 72
13 – 115
TANNER AGE
STAGE (years)
MALE
RANGE
(ug/dL)
MEAN
(ug/dL)
TANNER AGE
STAGE
(years)
FEMALE
RANGE
(ug/dL)
MEAN
(ug/dL)
1
2
3
4
5
13 – 83
42 – 109
48 – 200
102 – 385
120 – 370
36
93
122
206
230
1
2
3
4
5
19 – 144
34 – 129
32 – 226
58 – 260
44 – 248
40
72
88
120
148
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
A D U LT S
21 – 30 Years:
31 – 40 Years:
41 – 50 Years:
51 – 60 Years:
61 – 70 Years:
71 – 80 Years:
(E) Esoterix Test Number
M A L E R A N G E ( u g/ d L )
100 – 460
88 – 305
70 – 218
29 – 220
26 – 213
20 – 172
(L) LabCorp Test Number
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
F E M A L E R A N G E ( u g/ d L )
76 – 255
48 – 247
19 – 210
20 – 157
10 – 115
not determined
21
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Deox y cor ticoste rone (DOC)
5 00 1 24 (E)
BLOOD ASSAYS
5 00 1 38 (L )
R A NG E ( ng / d L )
P R E MAT U RE I NFA N TS
26 – 28 Weeks, Day 4:
34 – 36 Weeks, Day 4
20 – 105
28-78
N EW B O R N
Levels are markedly elevated at birth and
decrease rapidly during the first week to
the range of 7-49 as found in older infants.
FUL L–T ERM INFA N TS
1 – 11 Months:
P R E P U B E RTAL C HIL DREN
2 – 10 Years:
P U B E RTAL CHILDREN
AND ADU LT S
8:00 a.m.:
22
7 – 49
2 – 34
2 – 19
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Deox y py ridin olin es, Ur ine (Includes Cr e atinine)
5 0 01 2 7 (E )
URINE ASSAYS
5 0 02 11 (L )
R A NG E
A D U LT S
Males:
up to 5.4 nmole/mmole creatinine
Females:
Premenopausal:
Postmenopausal:
up to 7.4 nmole/mmole creatinine
up to 8.5 nmole/mmole creatinine
Results higher than the above ranges indicate an accelerated bone resorption rate.
Des ox y cor tis ol, 1 1- , (Compound S for M ety ra pone Test)
5 0 01 3 6 (E )
BLOOD ASSAYS
5 0 05 5 0 (L )
R A NG E ( u g / d L)
C HILDREN AND AD ULT S
Baseline:
<1
Post Metyrapone:
Single Dose Test:
Multiple Dose Test:
(E) Esoterix Test Number
7 – 18
10 – 25
(L) LabCorp Test Number
23
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Desox yco r tis ol, 1 1-, ( Specific Compound S)
5 00 1 32 (E)
BLOOD ASSAYS
5 00 1 71 (L )
R A N G E (n g / d L)
P R E MAT U RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
110 – 1376
48 – 579
FUL L–T ERM INFA N TS
3 Days:
31 Days – 11 Months:
13 – 147
< 10 – 156
P R E P U B E RTAL C HIL DREN
8:00 a.m.:
20 – 155
P U B E RTAL CHILD REN
AND ADU LT S
8:00 a.m.:
24
12 – 158
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
D ex am e t h a s o n e
BLOOD ASSAYS
5 0 01 4 0 (E )
50 0 11 8 ( L )
R A N G E ( n g /d L )
A D U LT S
Baseline:
< 30
8:00 a.m.
140 – 295
Following 1 mg Dexamethasone, Previous Evening
8:00 a.m.
1600 – 2850
Following 8 mg Dexamethasone, (4 x 2 mg Doses) Previous Day
(E) Esoterix Test Number
(L) LabCorp Test Number
25
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
D i hy d r o t e s t o s t e r o n e ( D H T )
BLOOD ASSAYS
5 00 1 44 (E)
5 00 1 42 (L )
M A L E R A N G E ( n g/ d L )
10 – 53
5 – 60
P RE MAT U RE IN FA N TS
F ULL– T ERM NEW B O RN S
F E M A L E R A N GE ( n g/ d L )
2 – 13
< 2 – 15
R A NG E ( ng / d L)
F ULL– T ERM NEW B O RN S
2 Weeks – 6 Months:
Male:
DHT decreases rapidly the first week, then increases to
12–85 ng/dL between 30–60 days. Levels then decrease
gradually to prepubertal values by seven months.
Female:
Levels decrease during the first month to < 3 ng/dL and
remain there until puberty.
P R E P U B E RTAL C HILD REN
<3
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(ng/dL)
1
2
3
4
5
<3
3 – 17
8
8 – 33
19
22 – 52 36
24 – 65 43
R A N GE ( n g/ d L )
A DU LT S
Male:
Female:
26
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
MEAN
(ng/dL)
TANNER
STAGE
FEMALE
AGE
(years)
RANGE
(ng/dL)
MEAN
(ng/dL)
1
2
3
4
5
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
<3
5 – 12
7 – 19
4 – 13
3 – 18
8
12
7
9
30 – 85
4 – 22
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
E s t ra d i o l
BLOOD ASSAYS
5 0 01 5 2 (E )
N EW B O R N
1 – 6 Months:
Male:
1 – 11 Months:
Female:
50 0 10 8 ( L )
R A NG E ( ng / d L )
Levels are markedly elevated at birth and fall rapidly during the first
week to prepubertal values of < 1.5 ng/dL.
Levels increase to 1.0 – 3.2 ng/dL between 30 and 60 days, then
decline to prepubertal levels of < 1.5 ng/dL by six months.
Levels increase to 0.5 – 5.0 ng/dL between 30 and 60 days, then
decline to prepubertal levels of < 1.5 ng/dL during the first year.
P R E P U B E RTA L C HILDRE N
1 – 10 Years:
< 1.5 ng/dL
P U B E RT Y
TANNER
STAGE
MALE
AGE
(years)
RANGE
(ng/dL)
MEAN
(ng/dL)
TANNER
STAGE
FEMALE
AGE
(years)
RANGE
(ng/dL)
MEAN
(ng/dL)
1
2
3
4
5
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
0.5 – 1.1
0.5 – 1.6
0.5 – 2.5
1.0 – 3.6
1.0 – 3.6
0.8
1.1
1.6
2.2
2.1
1
2
3
4
5
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
0.5 – 2.0
1.0 – 2.4
0.7 – 6.0
2.1 – 8.5
3.4 – 17
0.8
1.6
2.5
4.7
11
A D U LT S
Male:
0.8 – 3.5 ng/dL
Female:
Follicular:
Luteal:
Postmenopausal:
3 – 10 ng/dL
7 – 30 ng/dL
< 1.5 ng/dL
(E) Esoterix Test Number
(L) LabCorp Test Number
27
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
E s trogens, Total
BLOOD ASSAYS
5 00 1 48 (E)
5 00 7 14 (L )
R A NG E ( ng/ d L)
FUL L–T ERM INFA N TS
Newborn:
30 Days – 11 Months:
Male:
Female:
Markedly elevated at birth and fall rapidly during the first week
to < 2.5 by seven days.
Levels increase to 1.0 – 4.0 between 30 – 60 days then decline to
< 2.5 by 12 months
Levels increase to 1.0 – 6.0 between 30 – 60 days then decline to
< 2.5 by 12 months
P R E P U B E RTAL C HILD REN
1 – 10 Years:
< 2.5 ng/dL
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(ng/dL)
MEAN
(ng/dL)
TANNER AGE
STAGE
(years)
FEMALE
RANGE
(ng/dL)
MEAN
(ng/dL)
1
2
3
4
5
1.0 – 3.8
1.7 – 4.5
2.2 – 5.5
2.7 – 8.0
2.5 – 8.0
2.0
3.0
4.1
5.3
5.0
1
2
3
4
5
1.0 – 4.6
2.2 – 6.3
2.4 – 11
4 – 18
6 – 28
2.3
4.1
6.1
9.1
17
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
A DU LT S
Male:
2 – 8 ng/dL
Female:
Follicular:
6 – 20 ng/dL
Luteal:
16 – 40 ng/dL
Postmenopausal:
< 5 ng/dL
* Esoterix’ assay is specific for estrone and estradiol, and does not measure estriol.
28
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
E s t ro n e
BLOOD ASSAYS
5 0 01 7 2 (E )
5 0 06 3 4 (L )
R A N G E ( n g /d L )
N EW B O R N
Values are strikingly elevated at birth, then
decrease rapidly during the first week to
prepubertal levels of < 1.5.
P R E P U B E RTA L C HILDRE N
1 – 10 Years:
< 1.5 ng/dL
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(ng/dL)
MEAN
(ng/dL)
TANNER AGE
STAGE
(years)
FEMALE
RANGE
(ng/dL)
MEAN
(ng/dL)
1
2
3
4
5
0.5 – 1.7
1.0 – 2.5
1.5 – 2.5
1.5 – 4.5
2.0 – 4.5
1.1
1.6
2.1
3.3
3.2
1
2
3
4
5
0.4 – 2.9
1.0 – 3.3
1.5 – 4.3
1.6 – 7.7
2.9 – 10.5
1.3
2.1
3.0
3.6
6.1
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
A D U LT S
Male:
1.0 – 5.0 ng/dL
Female:
Follicular:
Luteal:
3.0 – 10 ng/dL
9.0 – 16 ng/dL
Postmenopausal:
< 4.0 ng/dL
(E) Esoterix Test Number
(L) LabCorp Test Number
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
29
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
F o l l i c l e St i m u l a t i n g H o r m o n e ( F S H ) I C M A
BLOOD ASSAYS
500192 (E) (Expressed in terms of W.H.O. International Standard,
5 00 09 7 (L )
Human Pituitary FSH 83/575)
R AN GE ( mIU/mL )
I NFA N TS
4 Weeks – 11 Months:
Male:
0.16 – 4.1
Levels are for infants from 4 weeks of age to one year. FSH in males
declines to prepubertal levels by the end of the first year.
Female:
0.24 – 14.2
Levels are for infants from 4 weeks of age to one year. FSH declines
more slowly than in males to reach prepubertal levels by the end
of the second year.
P R E P U B E RTAL C HILD REN
MAL E
FE M A LE
12 Months – 8 Years:
0.26 – 3.0
1.0 – 4.2
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(mIU/mL)
MEAN
(mIU/mL)
TANNER AGE
STAGE (years)
FEMALE
RANGE
(mIU/mL)
MEAN
(mIU/mL)
1
2
3
4
5
0.26 – 3.0
1.8 – 3.2
1.2 – 5.8
2.0 – 9.2
2.6 – 11.0
0.98
2.5
2.9
4.4
6.1
1
2
3
4
5
1.0 – 4.2
1.0 – 10.8
1.5 – 12.8
1.5 – 11.7
1.0 – 9.2
2.1
4.0
5.1
6.4
4.9
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 16.2
12.8 – 17.3
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
A D ULT
Males 20 – 50 Years: 2.0 – 9.2
Females 18 – 34 Years:
Follicular & Luteal: 1.8 – 11.2
Mid–cycle:
6 – 35
Post Menopausal: 30 – 120
30
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Fr uc tos am ine
BLOOD ASSAYS
5 0 06 0 8 (E )
R A NG E
< 285 umol/L
Glutamic Acid Deca r box ylase (GAD-65) Autoantibodies
5 0 02 3 6 (E )
A L L AG E S
50 0 61 1 ( L )
R AN G E
< 0.5 U/mL
G l y co M a r k
BLOOD ASSAYS
5 0 06 0 9 (E )
50 0 11 5 ( L )
R ANG ES
R E F E R E N C E I N T E R VA L
(ug/mL) 1 , 5 AG
ME A N ( S D )
( u g / m L) 1 , 5 A G
M ALE :
FE MALE :
10.7-32.0
6.8-29.3
22.5 (5.8)
17.7 (6.2)
(E) Esoterix Test Number
BLOOD ASSAYS
(L) LabCorp Test Number
31
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
G r o w t h H o r m on e A n t i b o d i e s
5 00 2 14 (E)
A L L AG E S
BLOOD ASSAYS
50 0 14 4 ( L )
R A N GE
Negative
G r o wt h H o r m o n e B i n d i n g Pr o t e i n ( G H B P )
5 00 2 09 (E)
BLOOD ASSAYS
5 00 1 77 (L )
R A N G E ( pm o l / L)
C HILD RE N
Under 2 Years:
3 – 10 Years:
10 – 15 Years:
<125 – 762
267 – 1638
431 – 1892
A D ULT S
20 – 50 Years:
686 – 2019
L A RON DWA R F I S M
< 125
32
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
G r o w t h H o r m o n e, I C M A
5 0 02 1 3 (E )
A L L AG E S
BLOOD ASSAYS
5 00 6 47 (L )
R AN G E
0 – 6 ng/mL
NOTE: GH is secreted episodically. An individual may have levels ranging from undetectable
to elevated over the course of a day.
RESPONSE TESTING (CHILDREN AND ADULTS):
GH response to provocative stimuli among normal individuals is highly variable. Response
values greater than 6 ng/mL using two-site assays have historically been considered to
reflect normal GH secretory function, while values below 6 ng/mL have been considered to
indicate some degree of GH deficiency. However, it should be noted that this limit is
arbitrarily derived. A significant percentage of normal controls exhibit response values well
below this 6 ng/mL limit.The clinical research literature should be consulted for a more
recent detailed review of the interpretation of GH response data.
(E) Esoterix Test Number
(L) LabCorp Test Number
33
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
G r o wt h H o r m o ne, R I A
5 00 2 12 (E)
BLOOD ASSAYS
50 0 63 2 ( L )
R A N G E ( n g/ m L )
N EW B O R N
1 Day:
2 – 7 Days:
31 Days – 11 Months:
5 – 53
5 – 27
2 – 10
Following an 8 – 12 hour overnight fast:
C HILD RE N
0–6
A D ULT S
0–6
RESPONSE TESTING (CHILDREN AND ADULTS):
The assessment of GH secretory capacity is complicated because of the episodic nature of
GH release from the pituitary. Basal GH levels can exhibit considerable variability throughout
a 24-hour period, thus limiting their clinical utility. Alternatively, measurement of GH
response to various stimuli has commonly been used to improve the diagnostic assessment
of GH secretion. GH response to provocative stimuli among normal individuals, however, is
highly variable. Response values greater than 10 ng/mL have historically been considered to
reflect normal GH secretory function, while values below 10 ng/mL have been considered to
indicate some degree of GH deficiency. However, it should be noted that this limit is
arbitrarily derived. A significant percentage of normal controls exhibit response values well
below this 10 ng/mL limit.The clinical research literature should be consulted for a more
recent detailed review of the interpretation of GH response data.
34
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
G r o w t h H o r m o n e, U r i n e ( I n c l u d e s C r e a t i n i n e )
5 0 02 1 1 (E )
URINE ASSAYS
5 00 3 30 (L )
R A NG E ( n g/ g c r e a t i n i n e )
O v e r n i g h t Co l l e c t i o n
P R E P U B E RTA L C HILDRE N
1 – 8 Years
7.5 – 42
P U B E RTAL C HILD REN
9 – 18 Years
6.7 – 39
A D U LT S
19 – 43 Years
0.2 – 14.8
2 4 h r Co l l e c t i o n
P R E P U B E RTA L C HILDRE N
1 – 8 Years
10.2 – 30.1
P U B E RTAL C HILD REN
9 – 18 Years
9.3 – 29
A D U LT S
19 – 43 Years
0.2 – 13
H e m o g l ob in A 1 c
BLOOD ASSAYS
5 0 20 8 0 (E )
A D U LT S
(E) Esoterix Test Number
5 01 2 70 (L )
R AN G E
4.2% – 5.9%
(L) LabCorp Test Number
35
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Hyd rox yco r ticoste roids, 1 7 , Ur ine (Includes Cr e atinine)
5 00 2 16 (E)
URINE ASSAYS
5 00 8 52 (L )
Glenn–Nelson Procedure
R A NG E
( m g/ 2 4 ho u r s )
R A NG E
( mg / g cr e a t i n i n e )
P R E P U B E RTAL C HIL DREN
1 – 4 Years:
5 – 9 Years:
0.2 – 2.5
0.5 – 2.5
1.7 – 6.4
2.2 – 6.0
P U B E RTAL CHILD REN
AND ADU LT S
Male:
Female:
3 – 10
2–6
2.4 – 4.3
1.6 – 3.6
36
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Hy d rox yco r ticos te rone, 1 8
BLOOD ASSAYS
5 0 00 8 8 (E )
50 0 77 8 ( L )
1 8 – O H – C o r t i co s t e r o n e
R A N GE ( n g/ d L )
1 8 – O H – C o r t i c o s t e r o n e/
A l d o s te r o ne R a t i o
R A N GE ( n g/ d L )
P R E M ATU RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
10 – 670
57 – 410
1.0 – 4.5
1.1 – 5.2
FU LL–TE RM I NFA N TS
3 Days:
31 Days – 11 Months:
31 – 546
5 – 220
2.6 – 5.3
2.3 – 6.0
C H IL DR EN
12 – 23 Months:
24 Months – 9 Years:
10 – 14 Years:
18 – 155
6 – 85
10 – 72
1.7 – 5.0
2.4 – 10.5
2.0 – 8.3
9 – 58
4 – 21
5 – 46
1.7 – 8.8
A D U LT S
8:00 a.m. Supine
8:00 a.m. Upright
Samples were collected without regard to posture from subjects on ad lib sodium
intake. For additional information on the effects of posture and sodium intake, contact
the laboratory.
(E) Esoterix Test Number
(L) LabCorp Test Number
37
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Hyd rox yindoleacetic Acid, 5- ( 5-HIAA), Ur ine
( Inc l udes Cr e ati n i n e )
5 00 2 15 (E)
A D ULT S
38
URINE ASSAYS
5 00 7 20 (L )
R AN GE( mg/24 h ou r)
< 16.0
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
H y d r o x y p r e g n e n o l o n e, 1 7 -
BLOOD ASSAYS
5 0 02 6 2 (E )
14 0 71 5 ( L )
R A NG E ( ng / d L )
P R E M ATU RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
375 – 3559
64 – 2380
FU LL–TE RM I NFA N TS
3 Days:
1 – 5 Months:
6c11 Months:
10 – 829
36 – 763
42 – 540
P R E P U B E RTA L C HILDRE N
12 – 23 Months:
24 Months – 5 Years:
6 – 9 Years:
14 – 207
10 – 103
10 – 186
P U B E RTAL AGE GROU P S
44 – 235
A D U LT S
53 – 357
(E) Esoterix Test Number
(L) LabCorp Test Number
39
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Hyd rox y p rogeste rone, 17 a- , (17-OHP)
BLOOD ASSAYS
5 00 2 70 (E)
5 00 1 63 (L )
R A N G E (n g / d L)
P R E MAT U RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
124 – 841
26 – 568
FUL L–T ERM INFA N TS
3 Days:
Male 1 – 11 Months:
Female 1 – 11 Months :
7 – 77
Levels increase after the first week to peak values
ranging from 40 – 200 ng/dl between 30 and 60 days.
Values then decline to prepubertal range before one year.
13 – 106
P R E P U B E RTAL C HIL DREN
1 – 10 Years:
3 – 90
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(ng/dL)
MEAN
(ng/dL)
1
< 9.8
3 – 90
38
2
9.8 – 14.5
5 – 115
51
3
10.7 – 15.4 10 – 138 57
4
11.8 – 16.2 29 – 180 80
5
12.8 – 17.3 24 – 175 97
A D ULT S
M A L E R A N G E ( n g/ d L )
27 – 199
40
TANNER AGE
STAGE (years)
FEMALE
RANGE
(ng/dL)
1
< 9.2
3 – 82
2
9.2 – 13.7 11 – 98
3
10.0 – 14.4 11 – 155
4
10.7 – 15.6 18 – 230
5
11.8 – 18.6 20 – 265
F E M A L E R AN G E ( n g / d L )
Follicular:
Luteal:
MEAN
(ng/dL)
31
49
70
290
108
15 – 70
35 – 290
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
I C A - 5 12 Au t o a nt i b o d i e s * R U O *
5 0 02 5 5 (E )
BLOOD ASSAYS
1 41 5 31 (L )
R A NG E
< 1.0 U/mL
A L L AG E S
I G F B i n d i n g Pr o t e i n - 1 ( I G F B P - 1 )
5 0 02 8 3 (E )
BLOOD ASSAYS
14 0 82 2 ( L )
R A N GE ( n g / m L )
P R E P U B E RTA L C HILDRE N
Fasting:
Random:
30 – 1000
10 – 500
P U B E RTAL C HILD REN
Fasting:
Random:
20 – 200
20 – 100
A D U LT S
Fasting:
Random:
10 – 150
0 – 40
(E) Esoterix Test Number
(L) LabCorp Test Number
41
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
I G F B i n d i n g Pr o t e i n - 2 ( I G F B P - 2 )
5 00 2 84 (E)
0 – 11 Months:
12 – 23 Months:
24 Months – 5 Years:
6 – 9 Years:
10 – 14 Years:
15 – 24 Years:
25 – 44 Years:
45 – 64 Years:
65 – 74 Years:
75 – 85 Years:
42
BLOOD ASSAYS
5 0 01 3 3 (L )
R A N G E ( n g/ m L )
348 – 922
280 – 750
275 – 700
255 – 540
200 – 470
215 – 518
220 – 570
225 – 710
225 – 850
300 – 1038
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
I G F B i n d i n g Pr o t e i n - 3 ( I G F B P - 3 )
BLOOD ASSAYS
5 0 02 8 1 (E )
5 00 6 44 (L )
R A NG E ( m g/ L )
M EA N ( m g/ L )
P R E M ATU RE I NFA N TS
0 Days – 1 Month:
2 – 3 Months:
4 – 5 Months:
6 –11 Months:
0.3 – 1.4
0.9 – 2.3
0.4 – 2.2
1.0 – 2.3
0.9
1.6
1.5
1.5
FU LL- TE RM INFA N TS
0 Days – 1 Month:
2 – 3 Months:
4 – 5 Months:
6 –11 Months:
0.4 – 1.7
0.5 – 2.1
0.6 – 2.4
0.5 – 2.4
0.9
1.3
1.4
1.4
C H IL DR EN
12 Months – 4 Years:
5 – 6 Years:
7 – 8 Years:
9 – 11 Years:
12 – 13 Years:
14 – 15 Years:
16 – 18 Years:
0.8 – 3.0
1.5 – 3.4
2.1 – 4.2
2.0 – 4.8
2.1 – 6.2
2.2 – 5.9
2.5 – 4.8
2.1
2.4
3.0
3.3
3.8
4.2
3.8
A D U LT S
19 – 30 Years:
31 – 70 Years:
2.0 – 4.2
1.9 – 3.6
3.0
2.7
(E) Esoterix Test Number
(L) LabCorp Test Number
43
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
IGF- I
BLOOD ASSAYS
5 00 2 82 (E)
5 00 4 85 (L )
T ERM
R A NG E ( ng / m L)
P R E – T E R M*
R A NG E ( ng / m L)
15 – 109
15 – 109
7 – 124
7 – 93
15 – 101
21 – 93
23 – 163
23 – 171
15 – 132
15 – 179
N EWBORNS A ND INFA N TS
Birth:
1 Day – 2 Months:
3 – 4 Months:
5 – 6 Months:
7 – 11 Months:
* Values from preterm infants were determined at these ages from expected term gestation
MAL E
F EM A LE
CHILD REN AND YOUNG AD ULT S
1 – 2 Years:
3 – 4 Years:
5 – 6 Years:
7 – 8 Years:
9 – 10 Years:
11 – 12 Years:
13 – 14 Years:
15 – 16 Years:
17 – 18 Years:
19 – 20 Years:
30 – 122
54 – 178
60 – 228
113 – 261
123 – 275
139 – 395
152 – 540
257 – 601
236 – 524
281 – 510
56 – 144
74 – 202
82 – 262
112 – 276
140 – 308
132 – 376
192 – 640
217 – 589
176 – 452
217 – 475
A D ULT S
21 – 30 Years:
31 – 40 Years:
41 – 50 Years:
51 – 60 Years:
61 – 70 Years:
71 – 80 Years:
155 – 432
132 – 333
121 – 237
68 – 245
60 – 220
36 – 215
87 – 368
106 – 368
118 – 298
53 – 287
75 – 263
54 – 205
44
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
I GF-I I
BLOOD ASSAYS
5 0 02 2 8 (E )
14 1 77 0 ( L )
P R E P U B E RTA L
R A NG E ( ng / m L)
334 – 642
P U B E RTA L
245 – 737
A D U LT S
288 – 736
I nsu l i n
BLOOD ASSAYS
5 0 02 2 0 (E )
50 0 56 4 ( L )
R A NG E ( u U / m L )
Following a 4 –12 hour fast:
0 – 8 Years
0 – 13
P U B E RTAL C HILDREN
AND AD ULT S
0 – 17
A D U LT S
2 Hours Post Meal
(Sustacal):
7.6 – 26
2 Hours Post
Glucose (75 gm):
15 – 53
(E) Esoterix Test Number
(L) LabCorp Test Number
45
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
I n s u l i n An t i b o d i e s
BLOOD ASSAYS
5 00 2 25 (E)
1 4 15 9 8 (L )
BINDING C A PAC I T Y (uU/mL)
C HIL D RE N:
4 – 19 Years:
< 5.0
A D ULT S :
20 – 40 Years:
< 5.0
T Y P E I D IA B ET E S
5 – 420
46
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
I ns ulin , Fr ee and Tot al
BLOOD ASSAYS
5 0 02 2 6 (E )
R A N G E ( u U / m L)
N O N – DI ABE TI C
In the absence of insulin–binding antibodies, the free and total
insulin assays are equivalent. However, this assay is intended for
use in diabetics with insulin autoantibody present. Measurement
is performed on acid–treated samples and,therefore,the sensitivity
and absolute values by this method may differ from our direct
insulin RIA.
Following a 4 – 12 hour fast:
I N FA N TS A ND PR EP U BERTAL
C H IL DR EN
0 -13 uU/mL
P U B E RTAL C HILDREN
AND AD ULT S
0 -17 uU/mL
I NSULI N D EP END ENT
D I AB ET IC PAT I E N TS
Total insulin levels are dependent on the binding capacity of
circulating antibodies and the patient’s insulin dose.Values
range from about 50 uU/mL to more than 1000 uU/mL. Free
insulin levels vary depending on the capacity and affinity of
circulating insulin–binding antibodies and the dose of insulin
given to the patient.Values range from non–diabetic levels up
to about 100 uU/mL.
(E) Esoterix Test Number
(L) LabCorp Test Number
47
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
K e t o s t e r o i d s, 1 7 - , ( 1 7 - K S ) , U r i n e (I n cl u d e s C r e a t i n i n e )
URINE ASSAYS
5 00 2 30 (E)
C HILD RE N
1 – 4 Years
5 – 9 Years:
10 – 12 Years:
13 – 14 Years:
15 – 16 Years:
Male:
Female:
A D ULT S
Male:
Female:
48
R A N GE
(m g / 2 4 ho u r s )
R A N GE
(m g / g c r e a t i n i n e )
< 1.0 – 2.0
< 1.0 – 3.2
1.0 – 5.0
1.0 – 5.5
Not Determined
Not Determined
Not Determined
Not Determined
3.0 – 13
2.5 – 8.0
Not Determined
Not Determined
10 – 25
6 – 14
6 .7 – 12
5.6 – 10
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
L e p ti n
BLOOD ASSAYS
5 0 02 3 7 (E )
5 00 7 16 (L )
R A NG E ( ng / m L)
M ALE
R A NG E ( ng / m L)
F EM A LE
0.7 – 5.3
3.3 – 18.3
A D U LT S (BMI = 22)
Range is 5th – 95th percentile.
NOTE: Leptin values are gender–dependent and highly correlated with the Body Mass Index
(BMI).This reference range is provided only for an average BMI value. Contact Esoterix to
obtain reference ranges correlated with other BMI’s.To obtain appropriate data, please
furnish patient’s age and sex, plus height and weight, or BMI.
(E) Esoterix Test Number
(L) LabCorp Test Number
49
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
L u t e i ni z i n g H o r m o n e ( L H ), I C M A
BLOOD ASSAYS
5 00 2 34 (E)
5 0 00 9 4 (L )
R A NG E (m I U / m L )
(Expressed In Terms of W.H.O. 2ND International Standard, Human Pituitary LH 80/552)
I NFA N TS
2 Weeks – 11 Months:
Values begin to increase about two weeks after birth to a range
of 0.02 – 7.0 mIU/mL within the first three months, then decline
to prepubertal values by the end of the first year.
P R E P U B E RTAL C HIL DREN
12 Months – 8 Years:
0.02 – 0.3
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(mIU/mL)
MEAN
(mIU/mL)
TANNER AGE
STAGE (years)
FEMALE
RANGE
(mIU/mL)
MEAN
(mIU/mL)
1
2
3
4–5
0.02 – 0.3
0.2 – 4.9
0.2 – 5.0
0.4 – 7.0
0.09
1.8
1.9
2.6
1
2
3
4–5
0.02 – 0.18
0.02 – 4.7
0.10 – 12.0
0.4 – 11.7
0.06
0.72
2.3
3.3
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 17.3
A D ULT S
Male:
Female:
Follicular:
Mid–cycle:
Luteal:
Postmenopausal:
50
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 18.6
1.5 – 9.0 mIU/mL
2.0 – 9.0 mIU/mL
18.0 – 49.0 mIU/mL
2.0 – 11.0 mIU/mL
20.0 – 70.0 mIU/mL
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
M a cro prola c t i n
BLOOD ASSAYS
5 0 03 7 5 (E )
50 0 32 4 ( L )
R A NG E
< 50%
(E) Esoterix Test Number
(L) LabCorp Test Number
51
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
M e t a n e p h r i n e s , F r ac t i o n a t e d U r i n e
URINE ASSAYS
5 00 2 40 (E)
501533(L)
R A N GE
( u g/ 2 4 h o u r s )
R A N GE
( ug / g c r e a t i n i n e )
N OR ME TA NE P H RI N E
C HILD RE N
< 1 Year:
1 – 2 Years:
2 – 8 Years:
8 – 15 Years:
Not Determined
Not Determined
Not Determined
Not Determined
180 – 1900
250 – 830
150 – 735
95 – 705
A D ULT S :
110 – 720
109 – 596
M E TA N E P HR IN E
C HILD RE N
< 1 Year:
1 – 2 Years:
2 – 8 Years:
8 – 15 Years:
Not Determined
Not Determined
Not Determined
Not Determined
150 – 310
60 – 250
55 – 460
70 – 380
A D ULT S
35 – 278
22 – 205
Pediatric values were determined on both random and overnight urine collections.
52
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
M etaneph rines, Total , Ur ine (Includes Cr eatinine)
5 0 02 4 2 (E )
URINE ASSAYS
50 0 48 0 ( L )
R AN G E
(u g / 2 4 h our s )
R AN G E
( u g /g c re a t i n i n e )
C H IL DR EN
Birth – 1 Year:
1 – 2 Years:
2 – 8 Years:
8 – 15 Years:
Not Determined
Not Determined
Not Determined
Not Determined
410 – 2000
300 – 1200
200 – 900
140 – 830
A D U LT S
300 – 900
180 – 700
Pediatric values were determined on both random and overnight collections.
M i c r o a l b u m i n , U r i ne ( Incl u d e s Cr e a t i n i n e )
5 0 24 4 0 (E )
A D U LT S
Overnight Collection:
24 Hour Collection:
(E) Esoterix Test Number
URINE ASSAYS
5 0 08 7 0 (L )
R AN G E
( m g/ 2 4 ho u r s )
R AN G E
( mg / g cr e a t i n i n e )
< 25
< 15
< 20
(L) LabCorp Test Number
53
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
N-Telopeptides, Ur ine (Includes Cr eatinine)
5 00 2 47 (E)
URINE ASSAYS
5 00 1 88 (L )
R A NG E
( n m o l e s BC E / m m o l e c r e a t i n i n e )
A D ULT S
Males and Premenopausal Females:
Postmenopausal Females:
Post Therapy:
10 – 65
25 – 110
Three to six months following
effective therapy, N-Telopeptide
values should decline to ≤ 35
nmoles BCE/mmole creatinine
or decrease by ≥ 40% of base
line value
BCE = Bone Collagen Equivalents
NOTE: Individuals exhibit significant daily variation in N-Telopeptide excretion. Postmenopausal values also vary over a wide range depending upon the stage of menopause
and the rate of bone resorption. Results are most useful when compared to a baseline value.
54
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
O s t e o ca l c i n
BLOOD ASSAYS
5 0 02 4 5 (E )
50 0 71 8 ( L )
0 – 11 Months:
R A N GE ( n g / m L )
5 – 25
P R E P U B E RTA L C HILDRE N
12 Months – 7 Years:
5 – 60
P U B E RTAL C HILD REN
8 – 9 Years:
10 – 11 Years:
12 – 15 Years:
30 – 103
37 – 154
42 – 225
A D U LT S
2 – 22
P a r a t hy r o i d H o r m o n e, I n t a c t ( I P T H ) ( I n c l u d e s C a l c i u m )
5 0 02 4 6 (E )
C HILDREN AND AD ULT S
(E) Esoterix Test Number
BLOOD ASSAYS
5 00 6 92 (L )
R A NG E
<10 – 65 pg/mL
(L) LabCorp Test Number
55
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
P r e g n a n e t r i o l , U r i n e ( I n c l u d e s C r e at i n i n e )
5 00 2 56 (E)
5 0 03 4 0 (L )
I NFA N TS
R AN GE ( m g/ g c r e a t i n i n e )
Not determined
C HILD RE N
0.1 – 0.9
A D ULT S
0.1 – 1.6
56
URINE ASSAYS
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
P r e g n en o l o ne
BLOOD ASSAYS
5 0 02 5 8 (E )
14 0 70 7 ( L)
R A NG E ( ng / d L )
P R E M ATU RE I NFA N TS
26 – 28 Weeks, Day 4:
260 – 2104
N EONAT E S
1 – 7 Days:
150 – 2000
Levels decrease after birth, and are within the prepubertal range by three months.
P R E P U B E RTA L C HILDRE N 20 – 140
P U B E RTAL AND ADULT S < 20 – 150
(E) Esoterix Test Number
(L) LabCorp Test Number
57
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
P r o g e s t e ro n e
BLOOD ASSAYS
5 00 2 66 (E)
5 00 1 67 (L )
MA LE S
1-16 Years
Adults
R A N G E ( n g /d L )
<10 – 15
<10 – 11
F EM A LE S
1 – 10 Years
11 Years
12 Years
13 Years
14 Years
15 Years
16 Years
R A NG E
<10 – 26
<10 – 255
<10 – 856
<10 – 693
<10 – 1204
<10 – 1076
<10 – 1294
A D ULT
C YCLE DAYS
1–6
7 – 12
13 – 15
16 – 28
R A NG E
<10 – 17
<10 – 135
<10 – 1563
<10 – 2555
P OST MENOPAU S A L
<10
Note: Luteal progesterone peaked from 350 to 3750 ng/dL on days ranging from 17 to 23.
58
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
P r o i ns u l i n, P l a s ma
BLOOD ASSAYS
5 0 02 7 2 (E )
5 00 7 22 (L )
P RO I N S U L I N
R A NG E (p M / L)
P RO I N S U L I N / I N S U L I N *
( M o l a r R a ti o As % )
R A NG E
N O R MA L CH I L DR E N
Fasting:
1.8 – 10
6.4 – 16
NORMA L AD ULT S
Fasting:
1.7 – 12
3.4 – 21
* Ratio calculated using actual insulin value, not the sum of insulin and proinsulin in the
denominator.
P r o lac t i n
BLOOD ASSAYS
5 0 02 7 4 (E )
5 00 5 57 (L )
R A NG E ( ng / m L)
N EW B O R N
1 – 7 Days:
1 – 8 Weeks:
30 – 495
Values decline during the first two months
of life to those observed in adult males 3-18
and females 3-24.
C HILDREN AND AD ULT S
Male:
3 – 18
Female:
3 – 24
(E) Esoterix Test Number
(L) LabCorp Test Number
59
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
R e n i n , P l a s m a ( P l a s m a R e n i n Ac t i v i t y )
5 00 2 78 (E)
BLOOD ASSAYS
5 00 4 58 (L )
R A N G E ( n g/ d L / hr )
P R E MAT U R E
1 – 7 Days:
1100 – 16, 700
FU L LT E R M
1 – 7 Days:
200 – 3500
Plasma renin activity in newborns is elevated and highly variable. Premature infants
generally exhibit substantially higher values ranging from 1100 – 16,700 ng/dL/hr.
C HILD RE N*
31 Days – 11 Months:
12 Months – 2 Years:
3 – 4 Years:
5 – 9 Years:
10 – 14 Years:
235 – 3700
171 – 1115
100 – 650
50 – 585
50 – 330
A D ULT S **
S U PI NE
UPR IGHT
R A N G E ( n g/ d L / hr ) R A N G E ( n g/ d L / hr )
20 – 160
70 – 330
* Normal Sodium Diet, Supine Posture
** Normal Sodium Diet
NOTE: Normal studies of plasma renin activity in young children and adolescents
are incomplete.
60
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
S ex Ho r m o n e B i n d i ng G l o b u l i n ( S H B G ) , I R M A
5 0 02 9 9 (E )
BLOOD ASSAYS
5 00 8 48 (L )
R A N G E (n m o l / L)
I N FA N TS
1 Month – 2 Years:
60 – 252
P R E P U B E RTA L C HILDRE N
2 – 8 Years:
72 – 220
P U B E RTAL AG E S
Males:
Females:
16 – 100
36 – 125
A D U LT S
Males:
Females:
Premenopausal
Postmenopausal
(E) Esoterix Test Number
20 – 60
40 – 120
28 – 112
(L) LabCorp Test Number
61
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Tes toste rone, B io available
BLOOD ASSAYS
5 00 2 88 (E)
5 00 6 50 (L )
R A N G E (n g / d L)
I NFA N TS AN D P RE P UB ERTAL
C HILD RE N
1 – 9 Years:
< 0.2 – 1.3 ng/dL
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(ng/dL)
1
2
3
4–5
< 0.2 – 3.4
2 – 58
12
12 – 70
30
84 – 350 210
< 9.8
9.8 – 14.5
10.7 – 15.4
11.8 – 17.3
MEAN
(ng/dL)
A D ULT S
Male:
20 – 39 Yrs:
40 – 49 yrs
50 – 69 yrs
70 – 79 yrs
128 – 430
95 – 350
95 – 285
60 – 240
Female:
1.1 – 14.3
TANNER AGE
STAGE (years)
FEMALE
RANGE
(ng/dL)
1
2
3
4–5
< 0.2 – 3.4
0.8 – 4.7 3.6
1.1 – 9.6 4.7
2.3 – 13.9 6.1
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 18.6
MEAN
(ng/dL)
R A NG E ( ng / d L )
NOTE: For additional information on interpretation of Bioavailable Testosterone levels,
contact the laboratory.
62
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Testoste rone, Fr ee
BLOOD ASSAYS
5 0 02 9 0 (E )
FU LL–TE RM I NFA N TS
1 – 15 Days:
1 – 2 Months:
3 – 4 Months:
5 – 6 Months:
50 0 10 2 ( L )
M A L E R A N G E ( p g / mL )
F E M A L E R A N G E ( p g/ m L)
1.5 – 31
3.3 – 18
0.7 – 14
0.4 – 4.8
0.5 – 2.5
0.1 – 1.3
0.3 – 1.1
0.2 – 0.6
P R E P U B E RTA L C HILDRE N
1 – 10 Years:
0.15 – 0.6
P U B E RT Y
Same as males
Comprehensive values for free testosterone by dialysis for both
males and females throughout puberty are currently unavailable.
A D U LT S
52 – 280
% F R E E T E S TO S T E R O N E
M AL E RA NG E (%)
FU LL–TE RM I NFA N TS
1 – 15 Days:
0.9 – 1.7
1 – 2 Months:
0.4 – 0.8
3 – 4 Months:
0.4 – 1.1
5 – 6 Months:
0.4 – 1.0
P R E P U B E RTA L C HILDRE N
1 – 10 Years:
0.4 – 0.9
1.1 – 6.3
FE M AL E RA NG E (% )
0.8 – 1.5
0.4 – 1.1
0.5 – 1.0
0.5 – 0.8
Same as males
P U B E RT Y
Comprehensive values for free testosterone by dialysis for both
males and females throughout puberty are currently unavailable.
A D U LT S
1.5 – 3.2
(E) Esoterix Test Number
(L) LabCorp Test Number
0.8 – 1.4
63
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Tes toste rone, Total
BLOOD ASSAYS
5 00 2 86 (E)
P R E MAT U RE I NFA N TS
26 – 28 Weeks, Day 4:
31 – 35 Weeks, Day 4:
5 00 1 59 (L )
M A L E R A N G E ( n g/ d L )
F E M A L E R A NG E ( ng / d L)
59 – 125
37 – 198
R A NG E ( ng / d L )
5 – 16
5 – 22
FUL L–T ERM INFA N TS
Newborns 1 – 7 Months: 75 – 400
20 – 64
Male: Levels decrease rapidly the first week to 20 – 50 ng/dL, then increase to 60 – 400 ng/dL
(Mean = 190) between 20 – 60 days. Levels then decline to prepubertal range of
< 3 – 10 by seven months.
Female: Levels decrease during the first month to <10 ng/dL and remain there until puberty.
P R E P U B E RTAL C HIL DREN
1 – 10 Years:
< 3 – 10
P U B E RT Y
TANNER AGE
STAGE (years)
MALE
RANGE
(ng/dL)
MEAN
(ng/dL)
1
< 9.8
< 3 – 10
4.9
2
9.8 – 14.5
18 – 150 42
3
10.7 – 15.4 100 – 320 190
4
11.8 – 16.2 200 – 620 372
5
12.8 – 17.3 350 – 970 546
A D ULT S 20 – 50 Ye a r s
R A N G E (n g / d L)
Male:
350 – 1030
Female:
Premenopausal:
10 – 55
Postmenopausal:
7 – 40
64
TANNER AGE
STAGE (years)
FEMALE
RANGE
(ng/dL)
MEAN
(ng/dL)
1
2
3
4
5
< 3 – 10
7 – 28
15 – 35
13 – 32
20 – 38
4.9
18
25
22
28
< 9.2
9.2 – 13.7
10.0 – 14.4
10.7 – 15.6
11.8 – 18.6
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
T h y r o g l o b u l i n ( w / A n t i - t hy r o g l o b u l i n S c r e e n ) ,
Com prehe nsive
BLOOD ASSAYS
5 0 03 1 6 (E )
5 0 05 4 0 (L )
R A N GE ( n g / m L )
M EA N ( n g / m L )
T H Y ROGLOBULI N ICMA
P R E P U B E RTA L C HILDRE N
2.9 – 56
17
P U B E RTAL C HILD REN
AND AD ULT S
1.3 – 37
8.5
T H Y ROGLOBU LI N RI A
I N FA N TS
1 – 12 Months
12 –113
42
P R E P U B E RTA L C HILDRE N
5 – 72
29
P U B E RTAL C HILD REN
AND AD ULT S
< 3 – 39
16
T h y ro g l o b u l i n An t i b o d i es ( A n t i - T g )
5 0 00 3 8 (E )
BLOOD ASSAYS
5 0 05 5 5 (L )
R A N G E (I U / m L )
A L L AG E S
(E) Esoterix Test Number
0 – 100
(L) LabCorp Test Number
65
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
T h y r o i d Pe r o x i d a s e A n t i b o d i e s ( A n t i - T P O )
5 00 0 42 (E)
ALL AG E S
BLOOD ASSAYS
5 00 6 38 (L )
R AN GE ( IU/mL )
0 – 20
T h y r o i d S t i m u l a t i n g H o r mon e ( T S H ) , I C M A
5 00 3 05 (E)
BLOOD ASSAYS
5 00 4 77 (L )
R A NG E ( u U / m L )
P R E MAT U RE I NFA N TS
26 – 32 Weeks,
3 – 4 Days:
FULL T E RM IN FA N TS
4 Days:
Newborns:
0.8 – 6.9
1 – 11 Months:
1.3 – 16
TSH surges within the first 15 – 60 minutes of life reaching
peak levels between 25 – 60 at about 30 minutes.Values then
decline rapidly and after one week are within the dult
normal range.
0.9 – 7.7
P R E P U B E RTAL C HIL DREN
0.6 – 5.5
P U B E RTAL CHILD REN
AND ADU LT S
0.5 – 4.8
66
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
T h y rox i n e ( T - 4 )
BLOOD ASSAYS
5 0 03 1 0 (E )
50 0 34 8 ( L )
R A N G E (ug / d L )
P R E M ATU RE I NFA N TS
26 – 30 Weeks,
3 – 4 Days:
2.6 – 14.0
FU LL–TE RM I NFA N TS
1 – 3 Days:
1 Week:
1 – 11 Months:
8.2 – 19.9
6.0 – 15.9
6.1 – 14.9
P R E P U B E RTA L C HILDRE N
12 Months – 2 Years:
3 – 9 Years:
6.8 – 13.5
5.5 – 12.8
P U B E RTAL C HILD REN
11 – 17 Years:
4.9 – 13.0
A D U LT S
4.2 – 13.0
(E) Esoterix Test Number
(L) LabCorp Test Number
67
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Thy roxine Binding Globulin ( T B G )
BLOOD ASSAYS
5 00 3 18 (E)
5 00 7 24 (L )
R A N G E (m g / d L)
T-4 /TBG R AT I O
P R E MAT U RE I NFA N TS
26 – 30 Weeks,
3 – 4 Days:
1.2 – 3.8
2.2 – 3.7
I NFA N TS
31 Days – 23 Months:
2.1 – 6.0
2.1 – 4.3
P R E P U B E RTAL C HIL DREN
2 – 9 Years:
2.0 – 5.3
1.7 – 4.0
P U B E RTAL CHILD REN
AND ADU LT S
1.8 – 4.2
1.8 – 4.5
T BG DE F IC IE N CY
0.1 – 0.9
4 – 42
68
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
T h y r o x i n e, F r ee
BLOOD ASSAYS
5 0 03 1 4 (E )
50 0 45 4 ( L )
R A N GE ( n g/ d L )
P R E M ATU RE I NFA N TS
26 – 30 Weeks,
3 – 4 Days:
0.4 – 2.8
FU LL–TE RM I NFA N TS
3 Days:
1 – 11 Months:
2.0 – 4.9
0.9 – 2.6
P R E P U B E RTA L C HILDRE N
0.8 – 2.2
P U B E RTAL C HILDREN
AND AD ULT S
0.8 – 2.3
(E) Esoterix Test Number
(L) LabCorp Test Number
69
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
Tr iiodothy ronine ( T-3)
BLOOD ASSAYS
5 00 3 22 (E)
5 00 5 63 (L )
R A NG E ( ng / d L )
P R E MAT U RE I NFA N TS
26 – 30 Weeks,
3 – 4 Days:
24 – 132
FUL L–T ERM INFA N TS
1 – 3 Days:
1 Week:
1 – 11 Months:
89 – 405
91 – 300
85 – 250
P R E P U B E RTAL C HIL DREN
119 – 218
P U B E RTAL CHILD REN
11 – 17 Years:
80 – 185
A D ULT S
55 – 170
Tr iiodothy ronine, Fr ee Only
5 00 3 23 (E)
A D ULT S
70
BLOOD ASSAYS
5 00 8 34 (L )
R A N G E ( p g /m L )
2.3 – 4.2
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
Tr iiodothy ronine, R ever se *RUO*
5 0 03 2 6 (E )
BLOOD ASSAYS
50 0 87 5 ( L )
R A NG E ( ng / d L )
N EW B O R N S
90 – 250
Reverse T–3 levels are elevated at birth and during the first few days of life. Values then
decrease rapidly and are within the adult range by one week.
C HILDREN AND AD ULT S 10 – 50
T S H Rec ep to r A nt i b o d y ( T R A b)
5 0 03 0 8 (E )
A L L AG E S
BLOOD ASSAYS
5 0 05 3 8 (L )
R A NG E ( U / L)
Antibody Titer
<1 U/L = Negative
1.1 - 1.5 U/L = Equivocal
>1.5 U/L = Positive
(E) Esoterix Test Number
(L) LabCorp Test Number
71
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
V a n i l l y l m a n d e l i c Ac i d ( V M A ) , U r i n e ( I n c l u d e s C r e a t i n i n e )
5 00 3 30 (E)
BLOOD ASSAYS
5 00 4 96 (L )
R A N GE
(m g / 2 4 ho u r s )
R A N GE
(m g / g c r e a t i n i n e )
C HILD RE N
Birth – 1 Year:
1 – 2 Years:
2 – 8 Years:
8 – 15 Years:
Not Determined
Not Determined
Not Determined
Not Determined
3 – 17
4 – 12
2 – 11
2 – 11
A D ULT S
0.7 – 6.8
1.5 – 7.0
Pediatric values were determined on both random and 8 hour urine collections.
Vitamin D, 1 , 25-Dihyd rox y
5 00 3 42 (E)
BLOOD ASSAYS
5 0 06 0 0 (L )
R A N G E ( p g /m L )
N EW B O R NS
0 – 30 Days
8 – 72
I NFA N TS AND CHILD REN
31 Days – 17 Years
15 – 90
A D ULT S
> 18 Years
21 – 65
72
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
E XP E CT E D VA LU E S
V itamin D, 25-Hyd rox y
BLOOD ASSAYS
5 0 03 3 8 (E )
50 0 51 0 ( L )
N E W B O R NS
R A NG E ( ng / m L )
5 – 42
C HILDREN AND AD ULT S
10 – 55
Note: Adult target levels are 32-100 ng/mL
Expected values apply to assays performed at Endocrine sciences only.
73
E X P E C T E D VA LU E S
E N DO C RI NO LO G Y
1. Cacclari, E., Cicognani, A., Pirazoli, P., Dallacosa, P., Mazzaracchio,
M.A.,Tassoni, P., Bernardi, F., Salardi, S., and Zappulle, F. GH, ACTH, LH and
FSH Behaviour in the First Seven Days of Life. Acta Paediatr. Scan. 65:
337, 1976.
2. Forest, M.G., and Bertrand, J. Sexual Steroids in Neonatal Period.
Abstracts of the 7th Congress of the International Study Group for
Steroids. J. Steroid Blochem. 6: xxiv, 1975.
3. Tanner, J.M., and Whitehouse, R.H. Clinical Longitudinal Standards for
Height, Weight, Height Velocity, and the Stages of Puberty. Arch. Dis.
Childhood 51: 170, 1976.
As used herein, Tanner stages in males encompass development of
both pubic hair and genitalia. In females, each stage encompasses
both pubic hair and breast development. While this expands the
chronological age range for each stage of pubertal development, it
results in a better correlation with hormonal values.
4. Day of cycle not determined for pubertal females.
5. Data adapted from De Peretti, E., and Forest, M.G. Unconjugated
Dehydroepiandrosterone Plasma Levels in Normal Subjects from Birth
to Adolescence in Human:The Use of a Sensitive Radioimmunoassay. J.
Clin. Endocrinol. Metab. 43: 982, 1976.
6. De Peretti, E., and Forest, M.G. Unconjugated Dehydroepiandrosterone
Plasma Levels in Normal Subjects from Birth to Adolescence in Human:
The Use of a Sensitive Radioimmunoassay. J. Clin. Endocrinol. Metab. 43:
982, 1976.
74
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
RE FE RE N C E S
7.
Results in children are not significantly different than those found in
adults. See Limal, J.M., Basmaciogullari, and Rapaport, R. Evaluation of
Single Oral Dose Metyrapone Tests in Children with Hypopituitarism.
Acta Paed. Scand. 65: 177, 1976.
8.
Data adapted from Pang, S., Levine, L.S., Chow, D., Sagiani, F., Saenger,
P., and New, M.I. Dihydrotestosterone and Its Relationship to
Testosterone in Infancy and Childhood. J. Clin. Endocrinol. Metab. 48:
821, 1979.
9.
Data adapted from Ducharme, J-R., Forest, M.G., De Peretti, E., Sempe,
M., Collu, R., and Bertrand, J. Plasma Adrenal and Gonadal Sex Steroids
in Human Pubertal Development. J. Clin. Endocrinol. Metab. 42:
468, 1976.
10. Bidlingmaier, F., Versmold, H., and Knorr, D. Sex Differences in Plasma
Estrogen Concentrations in Infancy. 21 Symp. Dtsch. Ges. Endokrin
Abstract 103. Acta Endoc. Suppl. 193: 103, 1975.
11. Data adapted from Bidlingmaier, F., Wagner-Barnack, M., Butenandt,
O., and Knorr, D. Plasma Estrogens in Childhood and Puberty under
Physiologic and Pathologic Conditions. Pediat. Res. 7: 901, 1973.
12. Sann, L., Chayvialle, J.A.P., Bremond, A., and Lambert, R. Serum Gastrin
Level in Early Childhood. Arch. Dis. Childhood 50: 782, 1975.
13. Data adapted from Janik, J.S., Akbar, A.M., Burrington, J.D., and Burke,
G. Serum Gastrin Levels in Infants and Children. Pediatrics 60: 60, 1977.
14. Luna, A.M., Wilson, D.M., Wibbeisman, C.J., Brown, R.C., Nagashima, R.J.,
Hintz, R.L., and Rosenfeld, R.G. Somatomedins in Adolescence: A CrossSectional Study of the Effect of Puberty on Plasma Insulin-Like
Growth Factor I and II Levels. J. Clin. Endocrinol. Metab. 57: 268, 1983.
(E) Esoterix Test Number
(L) LabCorp Test Number
75
REFERENCES
E N DO C RI NO LO G Y
15. Arnaud, S.B., Goldsmith, R.S., Stickler, G.B., McCall, J.T., and Arnaud, C.D.
Serum Parathyroid Hormone and Blood Minerals: Interrelationships in
Normal Children. Pediat. Res. 7: 485, 1973.
16. Hillman, L.S., Rojanasathit, S., Slatopolsky, E., and Haddad, J.G. Serial
Measurements of Serum Calcium, Magnesium, Parathyroid Hormone,
Calcitonin, and 25-Hydroxy-Vitamin D in Premature and Term Infants
During the First Week of Life. Pediat. Res. 11: 739, 1977.
17. Guyda, H.J., and Friesen, H.G. Serum Prolactin Levels in Humans from
Birth to Adult Life. Pediat. Res. 7: 534, 1973.
18. Aubert, M.L., Grumbach, M.M. and Kaplan, S.L. Heterologous
Radioimmunoassay for Plasma Human Prolactin (hPRL) Values in
Normal Subjects, Puberty, Pregnancy and in Pituitary Disorders. Acta
Endocrinol. 77: 460, 1974.
19. Stark, P., Beckerhoff, R., Leumann, E.P., Veter, W., and Siegenthaler, W.
Control of Plasma Aldosterone in Infancy and Childhood. Helv.
Paediat. Acta 30: 349, 1975.
20. Dillon, M.J., and Ryness, J.M. Plasma Renin Activity and Aldosterone
Concentration in Children. Brit. Med. Journ. 4: 316, 1975.
21. Sassard, J., Sann, L., Vincent, M., Francois, R., and Cier, J.F. Plasma Renin
Activity in Normal Subjects from Infancy to Puberty. J. Clin.
Endocrinol. Metab. 40: 524, 1975.
22. Data adapted from Forest, M.G., Cathiard, A.M., and Bertrand, J.A.
Evidence of Testicular Activity in Early Infancy. J. Clin. Endocrinol.
Metab. 37: 148, 1973.
76
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
RE FE RE N C E S
23. Forest, M.G., Sizonenko, P.C., Cathiard, A.E., and Bertrand, J.
Hypophysio- Gonadal Function in Humans During the First Year of
Life. J. Clin. Invest. 53: 819, 1974.
24. Forest, M.G., Cathiard, A.M., and Bertrand, J.A. Total and Unbound
Testosterone Levels in the Newborn and in Normal and Hypogonadal
Children: Use of a Sensitive Radioimmunoassay for Testosterone. J.
Clin. Endocrinol. Metab. 36: 1132, 1973.
25. Ket, J.L., De Vijlder, J.M., Bikker, H., Gons, M.H., and Tegelaers, W.H.H.
Serum Thyroglobulin Levels: The Physiological Decrease in Infancy
and the Absence in Athyroidism. J. Clin. Endocrinol. Metab. 53:
1301, 1981.
26. Penny, R., Spencer, C.A., Frasier, S.D., and Nicoloff, J.T. ThyroidStimulating Hormone and Thyroglobulin Levels Decrease with
Chronological Age in Children and Adolescents. J. Clin. Endocrinol.
Metab. 56: 177, 1983.
27. Chopra, I.J., Sach, J., and Fisher, D.A. Circulatory Reverse T-3 in the
Human Newborn. J. Clin. Invest. 55: 1137, 1975.
28. Raux-Eurin, M.G., Pham-Huu-Trung, M.T., Marrec, D., and Girard, F.
Plasma Aldosterone Concentrations during the Neonatal Period.
Pediat. Res. 11: 182, 1977.
29. Aperia, A., Broberger, O., Herin, P., and Zefterstrom, R. Sodium Excretion
in Relation to Sodium Intake and Aldosterone Excretion in Newborn
Pre-Term and Full-Term Infants. Acta Paediatr. Scand. 68: 813, 1979.
30. Follicular and luteal phases only; does not include midcycle peak.
(E) Esoterix Test Number
(L) LabCorp Test Number
77
S . I . UNI T CO NV E R S I O N TA B L E
E N DO C RI NO LO G Y
H O R MO NE
WHEN
YO U
K N OW
ACTH (Corticotropin)
Antidiuretic Hormone (ADH)
Albumin
Aldosterone, Serum
Aldosterone, Urine
Aldosterone/Creatinine
Androstanediol
Androstanediol Glucuronide
Androstenedione
Androsterone, Urine
Androsterone/Creatinine
Angiotensin I
Angiotensin II
Angiotensin III
Angiotensin I Converting Enzyme
Atrial Natriuretic Peptide (ANP)
C-Peptide
C-Peptide, Urine
C-Peptide/Creatinine
Calcitonin
Calcium
Calcium, Urine
pmol/L
4.5000
pmol/L
1.0840
g/L
0.1000
pmol/L
0.0360
nmol/d
0.3604
nmol/mmol 3.1859
pmol/L
0.0292
pmol/L
0.0469
pmol/L
0.0286
umol/d
0.2905
umol/mmol 2.5680
pmol/L
1.2960
pmol/L
1.0460
pmol/L
0.9310
U/L
1.0000
pmol/L
3.0800
nmol/L
3.0210
nmol/L
3.0210
nmol/mmol 26.7109
pmol/L
3.4180
mmol/L
4.0080
mmol/d
40.0800
78
M U LT I P LY
BY
TO
FIND
pg/mL
pg/mL
g/dL
ng/dL
ug/24 h
ug/g
ng/dL
ng/dL
ng/dL
mg/24 h
mg/g
pg/mL
pg/mL
pg/mL
mU/mL
pg/mL
ng/mL
ng/mL
ug/g
pg/mL
mg/dL
mg/24 h
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
S . I . UNI T CO N VE R S I O N TA B L E
HOR M O NE
WHEN
YO U
K N OW
Catecholamines, Urine
Catecholamines/Creatinine
Corticosterone
18-Hydroxycorticosterone
Cortisol, Serum
Cortisol, Urine
Cortisol/Creatinine
Cortisone
Creatinine, Urine
Cyclic Amp, Urine
Cyclic Amp/Creatinine
Dehydroepiandrosterone (DHEA)
Dehydroepiandrosterone-Sulfate
(DHEA-S)
Deoxycorticosterone (DOC)
18-Hydroxydeoxycorticosterone
(18-OH-DOC)
11-Desoxycortisol (Compound S)
Dexamethasone
Dihydrotestosterone (DHT)
Dopamine, Plasma
Dopamine, Urine
nmol/d
0.1762
nmol/mmol 1.5572
pmol/L
0.0347
pmol/L
0.0362
nmol/L
0.0363
nmol/d
0.3625
nmol/mmol 3.2045
pmol/L
0.0361
umol/d
0.1131
umol/L
1.0000
nmol/mmol 0.0088
pmol/L
0.0288
nmol/L
0.0368
ug/24 h
ug/g
ng/dL
ng/dL
ug/dL
ug/24 h
ug/g
ng/dL
mg/24 h
nmol/mL
umol/g
ng/dL
ug/dL
pmol/L
pmol/L
0.0331
0.0347
ng/dL
ng/dL
pmol/L
pmol/L
pmol/L
pmol/L
nmol/d
0.0346
0.0393
0.0290
0.1530
0.1530
ng/dL
ng/dL
ng/dL
pg/mL
ug/24 h
(E) Esoterix Test Number
(L) LabCorp Test Number
M U LT I P LY TO
BY
F IN D
79
S . I . UNI T CO NV E R S I O N TA B L E
E N DO C RI NO LO G Y
H O R MO NE
WHEN
YO U
K N OW
Dopamine/Creatinine
Endorphin, Beta
Epinephrine, Plasma
Ephinephrine, Urine
Epinephrine/Creatinine
Estradiol
Estriol
Estrogens, Serum
Estrone
Estrone Sulfate
Folic Acid
Follicle Stimulating Hormone (FSH)
Follicle Stimulating Hormone, Urine
FSH/Creatinine
Gastrin
Glucagon
Growth Hormone
Human Chorionic Gonadotropin
(HCG)
HCG, Urine
HCG/Creatinine
5-Hydroxyindoleacetic Acid
(5-HIAA), Urine
nmol/mmol 1.3528
pmol/L
4.0000
pmol/L
0.1831
nmol/d
0.1831
nmol/mmol 1.6186
pmol/L
0.0272
pmol/L
0.0288
pmol/L
0.0271
pmol/L
0.0270
pmol/L
0.0350
pmol/L
0.0441
IU/L
1.0000
IU/d
1.0000
IU/mmol 8.8420
ng/L
1.0000
ng/L
1.0000
ug/L
1.0000
IU/L
1.0000
ug/g
pg/mL
pg/mL
ug/24 h
ug/g
ng/dL
ng/dL
ng/dL
ng/dL
ng/dL
ng/dL
mIU/mL
IU/24 h
IU/g
pg/mL
pg/mL
ng/mL
mIU/mL
IU/d
IU/mmol
nmol/d
IU/24 h
IU/g
ug/24 h
80
M U LT I P LY
BY
1.0000
8.8420
0.1912
TO
FIND
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
S . I . UNI T CO N VE R S I O N TA B L E
HOR M O NE
WHEN
YO U
K N OW
M U LT I P LY TO
BY
F IN D
5-HIAA/Creatinine
nmol/mmol 1.6906
Homovanillic Acid (HVA), Urine
nmol/d
0.1822
HVA/Creatinine
nmol/mmol 1.6110
17-Hydroxycorticosteroids, Urine
nmol/d
0.3625
17-Hydroxycorticosteroids/Creatinine nmol/mmol 3.2045
IGF-I (Somatomedin C)
nmol/L
7.6490
IGF-II
nmol/L
7.5000
Inhibin
U/L
0.0010
Insulin
pmol/L
0.1394
17-Ketosteroids, Urine
umol/d
0.2884
17-Ketosteroids/Creatinine
umol/mmol 2.5495
Luteinizing Hormone (LH)
IU/L
1.0000
Luteinizing Hormone, Urine
IU/d
1.0000
LH/Creatinine
IU/mmol 8.8420
Metanephrine, Urine
nmol/d
0.1972
Metanephrine/Creatinine
nmol/mmol 1.7432
Metanephrines,Total, Urine
nmol/d
0.1902
Metanephrines,Total/Creatinine
nmol/mmol 1.6814
Methoxytyramine, Urine
nmol/d
0.1672
Methoxytyramine/Creatinine
nmol/mmol 1.4786
Norepinephrine, Plasma
pmol/L
0.1692
Norepinephrine, Urine
nmol/d
0.1692
Norepinephrine/Creatinine
nmol/mmol 1.4957
(E) Esoterix Test Number
(L) LabCorp Test Number
ug/g
ug/24 h
ug/g
ug/24 h
ug/g
ng/mL
ng/mL
U/mL
uU/mL
mg/24 h
mg/g
mIU/mL
IU/24 h
IU/g
ug/24 h
ug/g
ug/24 h
ug/g
ug/24 h
ug/g
pg/mL
ug/24 h
ug/g
81
S . I . UNI T CO NV E R S I O N TA B L E
E N DO C RI NO LO G Y
H O R MO NE
WHEN
YO U
K N OW
Normetanephrine, Urine
Normetanephrine/Creatinine
Osteocalcin
Parathyroid Hormone
Prednisolone
Prednisone
Pregnanediol, Urine
Pregnanediol/Creatinine
Pregnanetriol, Urine
Pregnanetriol/Creatinine
Pregnenolone
17-Hydroxypregnenolone
Progesterone
17-Hydroxyprogesterone
20-Hydroxyprogesterone
Prolactin
Renin (Plasma Renin Activity)
Reverse T-3
Secretin
Sex Hormone Binding Globulin
(SHBG)
nmol/d
0.1832
nmol/mmol 1.6195
nmol/L
6.5000
pmol/L
9.5000
pmol/L
0.0361
pmol/L
0.0358
umol/d
0.3205
ng/dLumol 2.8332
umol/d
0.3365
umol/mmol 2.9747
pmol/L
0.0317
pmol/L
0.0333
pmol/L
0.0315
pmol/L
0.0331
pmol/L
0.0317
ug/L
1.0000
ng/L/s
3.6000
pmol/L
0.0651
pmol/L
3.0550
nmol/L
0.0288
82
M U LT I P LY
BY
TO
FIND
ug/24 h
ug/g
ng/mL
pg/mL
ng/dL
pmol/L
mg/24 h
mg/g/mmol
mg/24 h
mg/g
ng/dL
ng/dL
ng/dL
ng/dL
ng/dL
ng/mL
ng/mL/h
ng/dL
pg/mL
ug/dL
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
S . I . UNI T CO N VE R S I O N TA B L E
HOR M O NE
WHEN
YO U
K N OW
(Binding Capacity)
Somatostatin-14
Somatostatin-28
Testosterone
Free Testosterone
Testosterone, Urine
Testosterone/Creatinine
Thyroglobulin
Thyroid Stimulating Hormone
(TSH)
Thyroxine (T-4)
Thyroxine Binding Globulin
Thyrotropin Releasing Hormone
(TRH)
Triiodothryonine (T-3)
Vanillylmandelic Acid (VMA), Urine
VMA/Creatinine
Vitamin B-12
25-Hydroxy-Vitamin D
1, 25-Dihydroxy-Vitamin D
(E) Esoterix Test Number
(L) LabCorp Test Number
M U LT I P LY TO
BY
F IN D
pmol/L
1.6380
pmol/L
3.2760
pmol/L
0.0288
pmol/L
0.2884
nmol/d
0.2884
nmol/mmol 2.5495
ug/L
1.0000
mU/L
1.0000
pg/mL
pg/mL
ng/dL
pg/mL
ug/24 h
ug/g
ng/mL
uU/mL
nmol/L
mg/L
pmol/L
ug/dL
mg/dL
pg/mL
0.0777
0.1000
0.3620
pmol/L
0.0651
nmol/d
0.1982
nmol/mmol 1.7525
pmol/L
0.1355
nmol/L
0.4006
pmol/L
0.4166
ng/dL
ug/24 h
ug/g
ng/dL
ng/mL
pg/mL
83
S . I . UNI T CO NV E R S I O N TA B L E
E N DO C RI NO LO G Y
H O R MO NE
WHEN
YO U
K N OW
M U LT I P LY
BY
TO
FIND
ACTH (Corticotropin)
Antidiuretic Hormone (ADH)
Albumin
Aldosterone, Serum
Aldosterone, Urine
Aldosterone/Creatinine
Androstanediol
Androstanediol Glucuronide
Androstenedione
Androsterone, Urine
Androsterone/Creatinine
Angiotensin I
Angiotensin II
Angiotensin III
Angiotensin I Converting Enzyme
Atrial Natriuretic Peptide (ANP)
C-Peptide
C-Peptide, Urine
C-Peptide/Creatinine
Calcitonin
Calcium
Calcium, Urine
pg/mL
pg/mL
g/dL
ng/dL
ug/24 h
ug/g
ng/dL
ng/dL
ng/dL
mg/24 h
mg/g
pg/mL
pg/mL
pg/mL
mU/mL
pg/mL
ng/mL
ng/mL
ug/g
pg/mL
mg/dL
mg/24 h
0.2222
0.9225
10.0000
27.7469
2.7747
0.3139
34.1997
21.3447
34.9162
3.4423
0.3894
0.7716
0.9560
1.0741
1.0000
0.3247
0.3310
0.3310
0.0374
0.2926
0.2495
0.0250
pmol/L
pmol/L
g/L
pmol/L
nmol/d
nmol/mmol
pmol/L
pmol/L
pmol/L
umol/d
umol/mmol
pmol/L
pmol/L
pmol/L
U/L
pmol/L
nmol/L
nmol/L
nmol/mmol
pmol/L
mmol/L
mmol/d
84
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
S . I . UNI T CO N VE R S I O N TA B L E
HOR M O NE
WHEN
YO U
K N OW
M U LT I P LY TO
BY
F IN D
Catecholamines, Urine
Catecholamines/Creatinine
Corticosterone
18-Hydroxycorticosterone
Cortisol, Serum
Cortisol, Urine
Cortisol/Creatinine
Cortisone
Creatinine, Urine
Cyclic Amp, Urine
Cyclic Amp/Creatinine
Dehydroepiandrosterone (DHEA)
Dehydroepiandrosterone-Sulfate
(DHEA-S)
Deoxycorticosterone (DOC)
18-Hydroxydeoxycorticosterone
(18-OH-DOC)
11-Desoxycortisol (Compound S)
Dexamethasone
Dihydrotestosterone (DHT)
Dopamine, Plasma
Dopamine, Urine
Dopamine/Creatinine
ug/24 h
ug/g
ng/dL
ng/dL
ug/dL
ug/24 h
ug/g
ng/dL
mg/24 h
nmol/mL
umol/g
ng/dL
ug/dL
5.6770
0.6422
28.8600
27.5938
27.5862
2.7586
0.3121
27.7393
8.8420
1.0000
113.1000
34.6741
27.2109
nmol/d
nmol/mmol
pmol/L
pmol/L
nmol/L
nmol/d
nmol/mmol
pmol/L
umol/d
umol/L
nmol/mmol
pmol/L
nmol/L
ng/dL
ng/dL
30.2572
28.8600
pmol/L
pmol/L
ng/dL
ng/dL
ng/dL
pg/mL
ug/24 h
ug/g
28.8684
25.4777
34.4353
6.5359
6.5359
0.7392
pmol/L
pmol/L
pmol/L
pmol/L
nmol/d
nmol/mmol
(E) Esoterix Test Number
(L) LabCorp Test Number
85
S . I . UNI T CO NV E R S I O N TA B L E
E N DO C RI NO LO G Y
H O R MO NE
WHEN
YO U
K N OW
M U LT I P LY
BY
TO
FIND
Endorphin, Beta
Epinephrine, Plasma
Ephinephrine, Urine
Epinephrine/Creatinine
Estradiol
Estriol
Estrogens, Serum
Estrone
Estrone Sulfate
Folic Acid
Follicle Stimulating Hormone (FSH)
Follicle Stimulating Hormone, Urine
FSH/Creatinine
Gastrin
Glucagon
Growth Hormone
Human Chorionic Gonadotropin
(HCG)
HCG, Urine
HCG/Creatinine
5-Hydroxyindoleacetic Acid
(5-HIAA), Urine
pg/mL
pg/mL
ug/24 h
ug/g
ng/dL
ng/dL
ng/dL
ng/dL
ng/dL
ng/dL
mIU/mL
IU/24 h
IU/g
pg/mL
pg/mL
ng/mL
mIU/mL
0.2500
5.4615
5.4615
0.6178
36.7107
34.6741
36.8450
36.9822
28.6123
22.6552
1.0000
1.0000
0.1131
1.0000
1.0000
1.0000
1.0000 I
pmol/L
pmol/L
nmol/d
nmol/mmol
pmol/L
pmol/L
pmol/L
pmol/L
pmol/L
pmol/L
IU/L
IU/d
IU/mmol
ng/L
ng/L
ug/L
U/L
IU/24 h
IU/g
ug/24 h
1.0000
0.1131
5.2301
IU/d
IU/mmol
nmol/d
86
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
S . I . UNI T CO N VE R S I O N TA B L E
HOR M O NE
WHEN
YO U
K N OW
Homovanillic Acid (HVA), Urine
ug/24 h
HVA/Creatinine
ug/g
17-Hydroxycorticosteroids, Urine
ug/24 h
17-Hydroxycorticosteroids/Creatinine ug/g
IGF-I (Somatomedin C)
ng/mL
IGF-II
ng/mL
IGF-II
ng/mL
Inhibin
U/mL
Insulin
uU/mL
17-Ketosteroids, Urine
mg/24 h
17-Ketosteroids/Creatinine
mg/g
Luteinizing Hormone (LH)
mIU/mL
Luteinizing Hormone, Urine
IU/24 h
LH/Creatinine
IU/g
Metanephrine, Urine
ug/24 h
Metanephrine/Creatinine
ug/g
Metanephrines,Total, Urine
ug/24 h
Metanephrines,Total/Creatinine
ug/g
Methoxytyramine, Urine
ug/24 h
Methoxytyramine/Creatinine
ug/g
Norepinephrine, Plasma
pg/mL
Norepinephrine, Urine
ug/24 h
Norepinephrine/Creatinine
ug/g
(E) Esoterix Test Number
(L) LabCorp Test Number
M U LT I P LY TO
BY
F IN D
5.4885
0.6207
2.7586
0.3121
0.1307
0.1333
0.1333
1000.0
7.1750
3.4674
0.3922
1.0000
1.0000
0.1131
5.0710
0.5736
5.2576
0.5948
5.9809
0.6764
5.9100
5.9100
0.6686
nmol/d
nmol/mmol
nmol/d
nmol/mmol
nmol/L
nmol/L
nmol/L
U/L
pmol/L
umol/d
umol/mmol
IU/L
IU/d
IU/mmol
nmol/d
nmol/mmol
nmol/d
nmol/mmol
nmol/d
nmol/mmol
pmol/L
nmol/d
nmol/mmol
87
S . I . UNI T CO NV E R S I O N TA B L E
E N DO C RI NO LO G Y
H O R MO NE
WHEN
YO U
K N OW
M U LT I P LY
BY
TO
FIND
Normetanephrine, Urine
Normetanephrine/Creatinine
Osteocalcin
Parathyroid Hormone
Prednisolone
Prednisone
Pregnanediol, Urine
Pregnanediol/Creatinine
Pregnanetriol, Urine
Pregnanetriol/Creatinine
Pregnenolone
17-Hydroxypregnenolone
Progesterone
17-Hydroxyprogesterone
20-Hydroxyprogesterone
Prolactin
Renin (Plasma Renin Activity)
Reverse T-3
Secretin
Sex Hormone Binding Globulin
(SHBG)
ug/24 h
ug/g
ng/mL
pg/mL
ng/dL
ng/dL
mg/24 h
mg/g
mg/24 h
mg/g
ng/dL
ng/dL
ng/dL
ng/dL
ng/dL
ng/mL
ng/mL/h
ng/dL
pg/mL
ug/dL
5.4585
0.6175
0.1538
0.1053
27.7393
27.9018
3.1201
0.3530
2.9718
0.3362
31.5956
30.0752
31.7965
30.2572
31.5956
1.0000
0.2778
15.3610
0.3273
34.6741
nmol/d
nmol/mmol
nmol/L
pmol/L
pmol/L
pmol/L
umol/d
umol/mmol
umol/d
umol/mmol
pmol/L
pmol/L
pmol/L
pmol/L
pmol/L
ug/L
ng/L/s
pmol/L
pmol/L
nmol/L
88
Expected values apply to assays performed at Endocrine Sciences only.
EN D O C RI N O LO G Y
S . I . UNI T CO N VE R S I O N TA B L E
HOR M O NE
(Binding Capacity)
Somatostatin-14
Somatostatin-28
Testosterone
Free Testosterone
Testosterone, Urine
Testosterone/Creatinine
Thyroglobulin
Thyroid Stimulating Hormone (TSH)
Thyroxine (T-4)
Thyroxine Binding Globulin
Thyrotropin Releasing Hormone
(TRH)
Triiodothryonine (T-3)
Vanillylmandelic Acid (VMA), Urine
VMA/Creatinine
Vitamin B-12
25-Hydroxy-Vitamin D
1, 25-Dihydroxy-Vitamin D
(E) Esoterix Test Number
(L) LabCorp Test Number
WHEN
YO U
K N OW
M U LT I P LY TO
BY
F IN D
pg/mL
pg/mL
ng/dL
pg/mL
ug/24 h
ug/g
ng/mL
uU/mL
ug/dL
mg/dL
pg/mL
0.6105
0.3053
34.6741
3.4674
3.4674
0.3922
1.0000
1.0000
12.8717
10.0000
2.7624
pmol/L
pmol/L
pmol/L
pmol/L
nmol/d
nmol/mmol
ug/L
mU/L
nmol/L
mg/L
pmol/L
ng/dL
ug/24 h
ug/g
ng/dL
ng/mL
pg/ml
15.3610
5.0454
0.5706
7.3779
2.4963
2.4004
pmol/L
nmol/d
nmol/mmol
pmol/L
nmol/L
pmol/L
89