Cost-effectiveness acceptability curve (CEAC). The CEAC illustrates the probability that a strategy is cost-effective given different willingness to pay
(WTP) thresholds. The probability that a strategy is cost-effective is plotted on the y-axis, and the WTP is plotted on the x-axis. As the WTP threshold
increases, the probability that a strategy is cost-effective increases. A strategy that has a 50% probability is equivalent to an equilibrium point where the
comparator also has a 50% probability of being cost-effective. If a strategy is dominant at all WTP thresholds, then the curve will be a straight line with a
100% probability of being cost-effective (denoted as Dominant strategy). However, when a strategy is dominated entirely across all WTP, then the curve
will be a straight line with no fluctuations and a 0% probability of being cost-effective (as denoted by Dominated strategy).
Source: Chapter 10. Understanding the Use of Pharmacoeconomic Analysis to Assess the Economic Impact of Pharmacogenomic Testing,
Pharmacogenomics: An Introduction and Clinical Perspective
Citation: Bertino JS, Jr, DeVane C, Fuhr U, Kashuba AD, Ma JD. Pharmacogenomics: An Introduction and Clinical Perspective; 2013 Available
at: http://mhmedical.com/ Accessed: July 28, 2017
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