Health Care Choice Modeling Training Jane Tang October 26, 2010 - All the flavors of conjoint analysis - History - What we do today, comparison of methods -“Calibration” - Market share vs. Choice Share - Forecasting – when do we need it? - Pricing for choice models - Input from clients - Key impact areas History of Conjoint • 1970s – Full Profile Conjoint – Rating/Ranking based Conjoint (Paul Green) – Dan McFadden introduced Choice theory in Transportation • 1980s – ACA & CBC – Rich Johnson invented Adaptive Conjoint Analysis – launching Sawtooth Software – Dick Wittink introduced Conjoint analysis (ACA) to patient-based health care research – Jordan Louviere introduced Choice Based Conjoint to Marketing • 1990s – HB estimation • 2000s – CBC Becomes Most Widely Used • 2008/9 – Adaptive CBC (A/CBC) was introduced. Overview of Conjoint Analysis: • Conjoint analysis is a popular marketing research technique that marketers use to determine what features a new product should have and how it should be priced. • Conjoint analysis became popular because it was a far less expensive (smaller sample size) and more flexible way to address these issues than concept testing. – When there are just too many potential product combinations for concept testing – Need to understand the tradeoff respondents make – Need to understand the competitive context http://intranet/download/attachments/10027862/Discrete+Choic e+Modeling+vs+Concept+Tests.pdf?version=1 Overview of Conjoint Analysis: • Conjoint analysis involving showing respondent potential product combinations. • Products can be factored into parts, called factors. Different options within each factor represents factor levels. • The basic premise of Conjoint Analysis that a respondent makes purchase decision based on the inherent value he places on factor levels. – He will tradeoff the levels within different factors. E.g. trade in his favourite color for lower price, etc… – However, the recent development of A/CBC has changed this where we non-compensatory rules are allowed. Overview of Conjoint Analysis: • These three steps form the basics of conjoint analysis: – collecting trade-offs: questionnaire with statistical design showing various options of the product, and respondents input in terms of product preference. – estimating buyer value systems: modeling by the analytics team. – making predictions: simulation based on the model developed. Analytics team working with you for results best suited to answer your client’s marketing question. Different flavors of a conjoint: Rating based Conjoint • We design conjoint cards that represent possible products based on factor levels. Respondents are asked to rate each cards in terms of purchase intent. Please rate this product in terms of how likely you would use it for your … patients? Use the scale where 1 being Very unlikely to use this product, and 10 being very unlikely to use this product. PRIMARY ENDPOINT (compared to Warfarin): Incidence of stroke or systemic embolism at the end of No warfarin data available treatment period (2 years) PRIMARY ENDPOINT (compared to Aspirin): 1.56% vs 2.6% for aspirin 40% Relative Rate Incidence of stroke or systemic embolism at the end of Reduction p<0.05 Statistically significant (compared to treatment period (2 years) aspirin) PRIMARY SAFETY ENDPOINT: OVERALL POPULATION (Compared to Warfarin) No warfarin data available Major Bleeding PRIMARY SAFETY ENDPOINT: WARFARIN NAIVE POPULATION Major Bleeding PRIMARY SAFETY ENDPOINT: OVERALL POPULATION 2.1% vs 1.48% for aspirin -42% Relative Rate (Compared to Aspirin) Reduction p<0.05 Statistically significant (compared to Major Bleeding aspirin) Dosing Oral, twice-daily Half life 10-15 hrs Renal Elimination 25% Average CHADS2 score of participants 2 • Alternatively we can show respondents a stack of cards and ask him to rank all the cards in terms of his preference. Different flavors of a conjoint: Rating based Conjoint • Analysis: based on regression. Linear (ratings), Logistic (ranking). • Individual level estimate is possible, i.e., each respondents will have a model based his own data: collect lots of information from each individual. • Problems: – Ratings: scale usage issues, “yeah”ers vs. “nay”ers. – Ranking: only works with very small problem • Output: – Preference for the various product options on the same rating scale • simulated preference rating – Relative preference for the various levels within each factor • Isotherm Different flavors of a conjoint: Adaptive Conjoint Analysis • Adaptive Conjoint Analysis (ACA): Sawtooth proprietary technology. Only works within the Sawtooth SSI Web interviewing interface. • Most popular conjoint technique in the 1990s. Still enjoys popularity among certain research area. • The respondent task is adaptive. That is, rather than a fixed statistical design, the respondent’s later conjoint tasks are determined by his preference selection made earlier. • Claims to be able to handle large number of factors: – by focusing respondents on a few factors that are considered most important through direct solicitation. Different flavors of a conjoint: Adaptive Conjoint Analysis • Output: – Similar to rating based, except we can simulate respondent’s share of preference for the product by assigning each respondent to his most preferred product. – The model is produced for each individual separately. It is possible at the end of the interview to then build an ideal product for each respondent. • E.g. Tailoring patient preference to treatment options. Different flavors of a conjoint: Self-Explicated Conjoint • The poor-man’s conjoint • Use direction questioning to get at respondent’s factor importance and preferences for the different levels within the factors. • allocate 100 points across all the factors • Rate each level within each factor in terms of preference. • Not recommended. What we do today: Choice Based Conjoint • Choice Based Conjoint: we design conjoint cards that represent possible products based on factor levels. Products are grouped into options within a card, and respondents are asked to choose within the group. • Over the last decade, academics and practitioners have favored choice over ratings-based methods: – Stronger mathematical theory (McFadden: MNL theory) – Stronger psychological underpinnings – Argued to be more accurate (comparison to market data) option1 One month free supply of medication Activiation is required in order to obtain the savings. option2 option3 Receive savings over 3 months: Pay no more than $22.50 in your Receive 60% off your co-pay for 6 first month, $20 in your second months month, and $17.50 in your third month. Includes a one month free supply of medication Includes a one month free supply of medication Activation is optional. A small additional financial discount per redemption will be provided with activation. Activation is optional. Additional disease education and/or health and wellness information will be provided with activation. What we do today: Discrete Choice Model • DCM is really just one type of CBC, where the focus is less on optimizing the product offer, more on the market competitive context. DCM CBC • • • Uses with multiple factors (6-10) to describe products Respondents are shown limited number of options per card (4-6). Usually come at the earlier stage in product development for – – – Market potential Best feature combination Rough price level • • • Mostly use Brand/Price combo to describe products Respondents are shown many options that represents most of the market Usually at later stage in product development to: – – Test for various marketing inputs, such as package, POS Determine pricing scenario, product lineup vs. competitions. CBC Choice Tasks DCM Choice Tasks What we do today: CBC & DCM • Output: the basic output is still the similar as those from ACA/Rating based conjoint – CBC: • Factor importance/Level preference - Isotherm • Simulation: simulator, product optimization • Individual level estimation allows you to further segment the respondents. – Potentially developing different optimized product for each segment. Caution: no simple typing tools for these. – DCM: • Usually no isotherm except for impact of packaging change, sale/promotions • Simulator: line optimization, pricing optimization • Unlike ACA, no individual level recommendation. Variations on CBC • MaxDiff/Best-Worst Scaling – One factor CBC – Often used for the stated importance question – Output: isotherm – relative preference of the items • Anchored MaxDiff – Add a direction question at the end – Turn relative preference to “absolute”/anchored preference • Adaptive MaxDiff – when there are too many items. Total Unweighted MaxDiff – Relative Preference Output, Anchored Attribute F Attribute K Attribute C Attribute Attribute Attribute Attribute Attribute Attribute Attribute Attribute Attribute D P E IJ G O B A M Attribute H Attribute N Attribute L Total sample Variations on CBC • Best-Worst Conjoint – Standard CBC – Ask respondents to choose both the most and least preferred option to get more data out of each respondent • Respondent can do this additional task very easily and quickly since they have already evaluated all the options – The additional information improves the model significantly. • To be tested: could mean potentially smaller sample/less number of tasks. – Output: same as before What we would like to do: Adaptive CBC • We have only done one of these study – internal R on R on technology product. Never been tried in health care. • Allows for non-compensatory decisions – What process do the respondents go through to make decisions? How likely will non-compensatory rules apply? – More likely in patient based research • Issues: – Longer interview length, 50%-100% longer – Sawtooth Proprietary software: respondents are routed out of Sparq for this portion. Market Share vs. Choice share • Choice shares are NOT market shares – 100% awareness, – 100% availability – “Overstatement” on the new products – “Price is no object” • In our experience, we generally under-estimate price elasticity – Other issues …. Comparison should only be made to the “BASE CASE” – not to current market share “Calibration” • When client insists on comparison to market information: – We calibrate the “Base Case” to market information: external effects adjustment – We apply the same adjustment to all the simulated scenarios – Effectively we are doing the same comparison – only that we have now moved the “Base Case”. – However, even the calibrated choice shares are still NOT the market shares. Forecast • Market Shares are NOT one-time measures. They reflect decisions consumers make over time. – Trial: first purchase - Would you buy it? – Repeat: subsequent purchases – Would you buy it again? • Calibrated choice shares, adjusted for media spend and marketing plans, can be used to assess “Trial”. – We have no information on “repeat”. DCM alone will not give you “forecast” • Bring in the “forecast” expert. • Dr. Lin Pricing for CBC – Analytics cost • A standard CBC is about 60 hrs in the PPE, – $9K internal cost • Analytics will bill you the actual hours only – If it will be more than 60 hrs, you will get notified. – Rosanna bills at a lower rate than Jane, but might take more time, so the cost will be about same in the end. – $15K external to the client • Your SBU keeps the difference CBC Pricing - what do we need from the client? • Sample specs: – Sample size • Who’s in the sample? How interested are they in this product? • Model specs: – Factors and levels • # of factors, how many levels in each • Restrictions: none/some/lots – How the factors go together. • Can we show everybody everything? – Or do we have to worry about scenarios? • Task specs: – What question is asked to respondents: • How many product options can we show? How many fixed competitive options? • What type of answers are we asking for? – Choose one vs. allocation What is reasonable? • If we can show multiple product options per task to the respondents, – A sample size of 300 physicians should support a model with 6 factors, each with 5 levels, with no restrictions in the model – We need n=1,500 patients for the same model – assuming 50% are interest in the product • If we can show one product option per task to the respondents, – A sample size of 300 physicians would only support a model with 4 factors, each with 3 levels – We need n=1,500 patients for the same model – assuming 50% are interest in the product Ask Jane or Sample planning paper or http://intranet/pages/viewpage.action?pageId=10027862 What impacts pricing? • Factors that impacts Analytics cost: – Complexity of the model: • • • • • restrictions scenarios Choices in stages/ selection from menus Large categorical factors: 8+ levels (except in MaxDiff) “unusual” requirements: purchases/ virtual shopping – Output requirement other than isotherm and simulator: • • • • • “Calibration” Optimization scenarios Premium calculations/Willingness-to-pay Standard error estimates on choice shares/ factor importance. Segmentations What impacts pricing? • Factors that impacts Sample/Ops cost: – Size of the model: • larger model requires more sample, • longer task length, more incentive – More complex design may require more programming and PM cost as well. • Options enabled/disabled based on previous choice on the same page • Adaptive factor levels – Virtual shopping http://intranet/display/research/Analytics [email protected]
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