Application for RESEARCH Protocol Using Animals Bio-Molecular Imaging Center (BMIC) Univ er s it y of W a sh in gt on Sout h L a k e Unio n Ca mpu s 81 5 M erc e r St ., Se at t l e, W A 9 8 10 9 Project #YY-NNNN Date Received: ( N o t e : i n e a c h " F o r m F i e l d " c e l l , c l i c k i n s i d e s h a d e d a r e a t o h i g h l i g h t & t h e n b e g i n e n t e r i n g yo u r d a t a ) ( T o e n t e r a n " X" i n t o a n y " c h e c k b o x" , d o u b l e - c l i c k o n t h e c h e c k b o x & s e l e c t " c h e c k e d " f r o m " D e f a u l t va l u e " ) PROTOCOL 1. INFORM ATION PROJECT TITLE SHORT TITLE (30 characters max.) which should be generic for the online schedule that is viewable by the general public ANTICIPATED STARTING DATE PROJECTED END DATE CONTACT 2. INFORMATION Principal Investigator Name: Title: Department: Box: Address: Phone: Fax: E-mail: 3. Primary Contact Name: Title: Department: Box: Address: Phone: Fax: E-mail: FUNDING 4. AGENCY INFORM ATION Funded Research Project Budget Information If funded project has a UW budget, please complete the information below: UW Budget Number: Budget Name: Source of Funding: Duration of Funding: Start date End Date: If funded project is not affiliated with the University of Washington, please provide the following information: Purchase order number: Contact Name: Phone Number: Contact Address: Protocol Development hours requested? D:\81895105.doc Yes No 1 Bio-Molecular Imaging Center (BMIC) Univ er s it y of W a sh in gt on Sout h L a k e Unio n Ca mpu s 81 5 M erc e r St ., Se at t l e, W A 9 8 10 9 5. Application for RESEARCH Protocol Using Animals Project #YY-NNNN Date Received: Brief summary of the proposed project. a) Objectives: b) Research Plan: D:\81895105.doc 2 Application for RESEARCH Protocol Using Animals Bio-Molecular Imaging Center (BMIC) Univ er s it y o f W a sh in gt on Sout h L a k e Unio n Ca mpu s 81 5 M erc e r St ., Se at t l e, W A 9 8 10 9 Project #YY-NNNN Date Received: Attachm ent E – CBIC MRI Pro cedures MRI PROCEDURES (To enter an "X" into each "check box" below, double-click on the check box & select "checked" from the "Default value") 6. Indicate who will be responsible for animal handling during imaging BMIC core personnel Personnel listed on this protocol in conjunction with BMIC core staff Personnel listed on this protocol working without assistance from BMIC staff (list personnel): 7. List the following for animals to be imaged: a) Number; b) Species; c) Sex; d) Age a) Number: ; b) Species: ; c) Sex: ; d) Age: 8. Duration and number of scanning sessions requested: a) Duration for each imaging session; b) Interval between sessions; c) Total number of imaging sessions per animal; d) Total number of sessions a) Duration of each imaging session: ; requested. b) Interval between sessions: ; c) Total number of sessions per animal: ; d) Total number of sessions requested: 9. Indicate whether the animals to be imaged have been exposed to any of the following: NO YES Infectious and hazardous agents (If yes, describe agents & usage precautions below) Human cells or blood (If yes, describe usage precautions below) Viral vectors (If yes, describe vectors & usage precautions below) Radioisotopes If "yes" to any of question number #4 above, please describe the agents or viral vectors that will be used and the precautions that will be taken to prevent personnel exposure: √ 10. Use of Contrast Agents No contrast agents will be used Contrast agents will be used in this study. If yes, please answer the following: Provide the following information for each contrast agent: a) Volume per injection & total volume per imaging session; b) Route & frequency of administration; c) Time interval between subsequent intervals a) Volume/injection & total volume/imaging session: b) Route & frequency of administraiton: c) Time interval between subsequent intervals: 11. ; ; Describe any procedures or treatments that will be given or performed on the animal(s) prior to or during imaging (e.g. Tail vein injections, perfusion, oral administration, etc.) √ D:\81895105.doc 3 Application for RESEARCH Protocol Using Animals Bio-Molecular Imaging Center (BMIC) Univ er s it y o f W a sh in gt on Sout h L a k e Unio n Ca mpu s 81 5 M erc e r St ., Se at t l e, W A 9 8 10 9 12 . NO Project #YY-NNNN Date Received: Indicate the additional instrumental equipment will be used: YES Physiological monitoring system ECG gating Respiratory gating Anesthesia 13. Describe the agents used for anesthesia (name of the agent, administration, dosage) √ 14. IACUC policy on rodent handling in bio-imaging core I have read and agree to adhere to the IACUC Policy on Rodent Handling in BMIC I have read and agree to adhere to the IACUC Policy on Rodent Handling in BMIC with the following exceptions. (list exceptions and provide scientific justification for requested change) 15. Animals originating from non-UW facilities Please indicate the name of the non-UW institute from which the animals originate: √ A copy of the IACUC approved animal protocol from the non-UW institution is attached. A copy of a complete protocol animal application for approval by the UW IACUC is attached. 16. BMIC Administrative Use A. Date application received: Study Number: B. Cost for the use of the BMIC 3T scanner: $ /hour x hours/each session=a): $ Total sessions=b): Total cost for the entire imaging study: a) x b) Charges for requested supplies Optical Disks - $95/ea DAT Tape - $6.00/ea Retrieval of Exam - $51.00 $ $ $ $ TOTAL SUPPLIES $ C. Reviewed and approved by the BMIC director Chun Yuan, PhD Signature Date Please submit this application as well as any requested documentation in both hard copy (signed) and electronic copy (MS Word document without signature) to Bio-Molecular Imaging Center, Box 358050, [email protected]. D:\81895105.doc 4
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