From: HIV Salvage Therapy Does Not Require Nucleoside Reverse Transcriptase InhibitorsA Randomized, Controlled Trial Ann Intern Med. 2015;163(12):908-917. doi:10.7326/M15-0949 Figure Legend: Time to regimen failure. Results in panel A are from an intention-to-treat analysis (all randomly assigned participants included). Results in panels B, C, and D are from an as-treated analysis (only participants who started study treatment; events occurring after discontinuation of NRTI assignment are censored). NRTI = nucleoside reverse transcriptase inhibitor. A. Secondary efficacy outcome: Time to primary outcome of regimen failure (first virologic failure or discontinuation of NRTI strategy). B. Primary safety outcome: Time to first grade 3 or 4 sign, symptom, or laboratory abnormality ≥1 grade higher than baseline. C. Secondary safety outcome: Time to first grade 3 or 4 sign or symptom ≥1 grade higher than baseline. D. Secondary safety outcome: Time to first grade 3 or 4 laboratory abnormality ≥1 grade higher than baseline. Date of download: 7/28/2017 Copyright © American College of Physicians. All rights reserved.
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