CURRICULUM VITAE
Carolina Verónica Barillas Mury
Address:
Telephone:
Fax:
Laboratory of Malaria and Vector Research
NIH/NIAID, Twinbrook III Facility,
12735 Twinbrook Parkway, Room 2E-20
Rockville, MD 20852
(301) 761 5059
(301) 480 1337
e-mail: [email protected]
PERSONAL INFORMATION
Place of Birth:
Citizenship:
Guatemala City, Guatemala, Central America
Guatemalan, American and Swiss
EDUCATION
B.S. Biology, Universidad del Valle de Guatemala, Guatemala, 1981
M.D. Medicine, Universidad Francisco Marroquín de Guatemala, Guatemala, 1985
Ph.D. Biochemistry, University of Arizona, Tucson, Arizona, 1992
APPOINTMENTS
Distinguished Investigator
2016-present
National Institutes of Health
Head of the Mosquito Immunity and Vector Competence Section
Laboratory of Malaria and Vector Research
Rockville, MD
Program Director
2015-present
Malaria Research Program
National Institute of Allergy and Infectious Diseases
National Institutes of Health
Senior Investigator
2010-2015
National Institutes of Health
Head of the Mosquito Immunity and Vector Competence Section
Laboratory of Malaria and Vector Research
Rockville, MD
Investigator
2003-2010
National Institutes of Health
Head of the Mosquito Immunity and Vector Competence Unit
Laboratory of Malaria and Vector Research
Rockville, MD
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Assistant Professor
1998 - 2003
Colorado State University
Department of Microbiology, Immunology and Pathology
Fort Collins, CO
Post Doctoral Fellow
1994-1998
European Molecular Biology Laboratory
Dr. Fotis C. Kafatos’ laboratory
Heidelberg, Germany
Post Doctoral Fellow
1993-1994
Harvard University,
Department of Cellular and Developmental
Biology, Dr. Fotis C. Kafatos’ laboratory,
Cambridge, MA
Research Associate
1992-1993
University of Arizona,
Biochemistry Department,
Dr. Michael Wells’ laboratory,
Tucson, AZ
Research Assistant
1987-1992
University of Arizona,
Biochemistry Department,
Dr. Michael Wells’ laboratory,
Tucson, AZ
Research Associate
1986-1987
Center for Studies of Sensory Impairment,
Aging and Metabolism (CeSSIAM),
National Committee of the Blind and Deaf of
Guatemala, Dr. Noel Solomons, Guatemala.
Research Assistant
1985-1986
Institute of Nutrition of Central America and
Panama (INCAP), Division of Nutrition and
Health, Dr. Noel Solomons, Guatemala.
HONORS, FELLOWSHIPS AND AWARDS
2016 Doctor Honoris Causa
Universidad del Valle de Guatemala.
In
recognition of distinguished professional
accomplishments.
2014 National Academy of Science
Elected as NAS Member. Primary Affiliation:
Section 44 - Microbial Biology. Secondary
Affiliation: Section 61-Animal, Nutritional,
and Applied Microbial Sciences
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2013 Sanofi/Pasteur Award
In recognition for her outstanding contributions
to understanding the mosquito immune responses
that affect malaria transmission.
2013 NIAID Outstanding Mentor Award
In recognition for an exceptional positive impact
on the professional development of post-doctoral
fellows.
2010 Bailey K. Ashford Medal
Awarded by the American Society of Tropical
Medicine and Hygiene for distinguished work in
tropical medicine.
2010 NIH/NIAID Individual Merit Award
In recognition of outstanding accomplishments in
advancing the understanding of malaria
transmission by mosquitoes, including mosquito
immune defenses and malaria parasite coping
mechanisms.
NIH/NIAID Annual Performance Awards
2004-2016
2005 NIH/NIAID Group Merit Award to the
Laboratory of Malaria and Vector Research
Outstanding Contributions and Efforts in
Support of the NIAID Mission
Swiss National Science Foundation
Training and Mobility of Researchers Fellowship,
1996-1998
European Molecular Biology Organization
Long Term Research Fellowship, 1995-1996
Alexander von Humboldt Foundation
Research Fellowship, 1994-1995.
Center for Insect Science
University of Arizona
Graduate Student Trainee Fellowship
1989-1991.
Faculty of Medicine
Univ. Francisco Marroquín de Guatemala
Best Thesis of the year 1986.
TEACHING EXPERIENCE
MB/PA 581 Biology of Disease Vectors (1998-2003) The purpose of the course was to
introduce graduate students working with vectors, vector borne diseases or veterinary medicine
to current advanced topics in vector physiology, genomics, new strategies in vector control and
tools to study vector/parasite/host interactions. Dr. Barillas-Mury established, organized and
taught this senior graduate levels course jointly with Dr. William Black while at Colorado State
University.
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FUNDING AGENCIES REVIEWER
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The French National Research Agency, Since 2012
NIH Drug Discovery and Mechanisms of Antimicrobial Resistance Study Section, June
2006
NIH Vector Biology Study Section, 2005
Medical Research Council, London, UK. Since 2005
The Welcome Trust, London, UK. Since 2001
Special Reviewer: Allergy, Immunology, and Transplantation Research Committee,
NIH, 1999.
ORGANIZATION OF INTERNATIONAL MEETINGS AND COURSES
Chair, Gordon Research Conference on Tropical Infectious Diseases, 2019
Vice-Chair, Gordon Research Conference on Tropical Infectious Diseases, 2017
Chair, NIH Malaria Research Program Mini-Symposium, NIH, December 2016
International steering committee member, Molecular Approaches to Malaria (MAM) Lorne,
Australia 2016
Co-organizer and speaker in the Keystone Symposium on “Malaria”, New Orleans,
Louisiana, January 2013. Chair of the “Biology of Plasmodium Transmission Stages” Session.
Co-organizer and Head of the Vector Biology Module. Biology of Parasitism: Modern
Approaches (2010 and 20111) Woods Hole Summer Course, MA. This is a unique course
for advanced graduate students, post-docs, and independent investigators, who are seeking
thorough training in modern approaches to the study of protozoan and helminthic parasites.
The focus of this course is on the molecular basis of parasite function and the
host/parasite/vector interaction with special emphasis on the most recent and exciting
developments in these areas.
Co-organizer of the Arthropod Immunity Workshop and the Parasite Immunity Section. 10th
International Congress of the International Society for Developmental and Comparative
Immunology, Charleston, South Carolina, July 2006
Co-organizer of the Keystone Symposium on “Genetic Manipulation of Insect Vectors”,
Taos, New Mexico, February 2004.
Co-organizer of the International Course on the Biology of Disease Vectors (BDV),
Colorado State University, Fort Collins, Colorado, June 2000. This is an intensive 2-week
course of international reputation that has been offered in CSU for the last 14 years. It includes
lectures and laboratory practices with participation of world experts in multiple disciplines.
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Organizer, coordinator and lecturer in the mini-symposium on “Insect and Vertebrate
Responses to Pathogens” which was offered as part of the BDV-2000 course.
PARTICIPATION IN GENOME ANNOTATION CONSORTIUMS
2006 Comparative genome and proteome analysis of Aedes aegypti, Anopheles gambiae and
Drosophila melanogaster immunity-related genes.
2002 Comparative genome and proteome analysis of Anopheles gambiae and Drosophila
melanogaster.
2002 Immunity-related genes and gene families in Anopheles gambiae.
PARTICIPATION IN COMMITEES

Chair of the NIH Promotion and Tenure Title-42 Subcommittee, 2013-present

Chair of the Laboratory of Malaria and Vector Research (LMVR) Insectary Safety
Committee, 2010-present

Associate Chair of the NIH Promotion and Tenure Title-42 Subcommittee, 2012-present

Member of the NIH Promotion and Tenure Title-42 Subcommittee, 2011-2012

Member of the Laboratory of Malaria Immunology and Vaccinology (LMIV) Senior
Scientist Search Committee, December, 2009.

Member of the NIH Program in Systems Immunology and Infectious Disease Modeling
(PSIIM) Search Committee to recruit three new NIH Investigators in: Computational
Biology, Infectious Diseases and Molecular/Cell Biology, Spring 2007.

Member of the CSU University College Research Council, 2001-2003.

Outside Member of the Animal Development Faculty Search Committee, Biology
Department, Spring 2001.

Member of the College Council for Higher Education departmental evaluation report,
Pathology Department 2001.

Member of the Education Sub-Committee, of the Departmental Reorganization Steering
Committee, Summer 2000.
5
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Outside Member of the Animal Development Faculty Search Committee, Biology
Department, Fall 1999.
MENTORSHIP
Thesis Advisor:
Joseph Bradley Charles
Cel. & Molec. Biol., CSU
M.S. 2001-2003
Giovanna Jaramillo-Gutierrez
Free University of Brussels &
NIH Graduate Partnership
Ph.D. 2006-2009
Gianmarco Raddi
NIH/Oxford/Cambridge
Program
PhD. 2015-present
LampouguinYenkoidiok-Douti
University of Maryland
NIH Graduate Partnership
PhD. 2016-present
Microbiology, CSU 2001-2003
Biochemistry, CSU 2001
NIH 2005 and 2006
NIH 2005
NIH 2005-2006
NIH 2005-2006
NIH 2006-present
NIH 2006-2007
NIH 2007
NIH 2008-2009
NIH 2010-2011
NIH 2011-2012
NIH 2011-2013
NIH 2012-2014
NIH 2013-2015
NIH 2013-2014
NIH 2015-2016
NIH 2015-2016
NIH 2015-present
NIH 2016-presetn
Honors Thesis
Pre-med student
Summer student
Summer student
Post-Bac IRTA
Post-Bac IRTA
NIH Academy
Post-Bac IRTA
Summer student
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Post-Bac IRTA
Undergraduate Student Training:
Lisa Vollmer
Ryan Ragle
Sara M. Leszczynski
Carrington Koebele
Joshua Lieberman
Rodolfo Zamora
Ekua Abban
Georges Ndikuyeze
Lindsay Kleeman
Jared Winikor
Amy Alabaster
Lois Bangiolo
Alejandro Padron
Emma Taylor Salmon
Nitin Kamath
Rebecca Greene
Bianca Nagata
Simardeep Nagyal
Bretta Hixson
Smith Agyingi
Visiting International Graduate Students:
Gracia Gomez Anduro
2004
Centro de Investigación en Alimentación
y Desarrollo, Hermosillo, México.
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Jose Henrique Maia Oliveira
2009
Institute of Medical Biochemistry,
Federal University of Rio de Janeiro
Renata de Lima Sales Gonçalves
2009
Institute of Medical Biochemistry,
Federal University of Rio de Janeiro
Ana Beatriz Barletta Ferreira
2014
Institute of Medical Biochemistry,
Federal University of Rio de Janeiro
Alessandra da Silva Orfano
2014
Laboratory of Medical Entomology,
Rene Rachou Institute, Fiocruz, Brazil
Former Post-Doctoral Fellows:
Dr. Yeon-Soo Han
1998-2003
Dr. Alvaro Molina-Cruz
2003-2006
Dr. Randall DeJong
Dr. Sanjeev Kumar
2004-2006
2002-2008
Dr. Lalita Gupta
2002-2008
Dr. Rajnikant Dixit
2007-2010
Dr. Janneth Rodrigues
2006-2011
Dr. Giselle Oliveira
2009-2012
Dr. Lindsey Garver
2009-2013
Dr. Urvashi Ramphul
2012-2015
Dr. Jose Luis Ramirez
2011-2015
Dr. Julio Cesar Castillo
2013-2016
Associate Professor and Department Head at
Chonnam National University, Korea.
Promoted to LMVR Staff Scientist in September
2006.
Associate Professor at Calvin College, Michigan.
Associate Professor, Birla Institute of Technology
and Science, Rajasthan, India
Associate Professor, Birla Institute of Technology
and Science, Rajasthan, India
Independent Researcher, National Institute of
Malaria Research (NIMR), Delhi, India
Scientist at GlaxoSmithKline (GSK), Tres Cantos,
Madrid, Spain
Visiting Researcher, Science without Borders
Program, Rene Rachou Institute, Fiocruz, Brazil
Senior Research Scientist, Vector and Parasite
Biology, Walter Reed Army Institute of Research
Senior Research Associate, Perrett Laver,
London
Research Entomologist, Agricultural Research
Service, USDA, Preoria, Illinois
Post-Doctoral Fellow, Dr. Jose Ribeiro’s
Laboratory, LMVR, NIH
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Current Post-Doctoral Fellows:
Dr. Gaspar Canepa
Dr. Fabio Mendonca Gomes
Dr. Nathani Trisnadi
Dr. Thiago Luiz Alves Silva
Dr. Ana Beatriz Barletta Ferreira
Dr. Caeul Lim
DISSERTATION COMMITEES
Bridget Robinson
Esther Sanchez Venable
Amy Rullkoetter
Lisa M. Williams
Kevin Myles
Andre Kipnis
Kristine Bennett
Francisco Diaz
Isabel Salazar Sanchez
Teresa Gollas Galvan
Gracia Gomez Andurro
NIH
NIH
NIH
NIH
NIH
NIH
Cel. & Molec. Biol., CSU
Foreign Languages, CSU
Pathology, CSU
Microbiology, CSU
Microbiology, CSU
Microbiology, CSU
Microbiology, CSU
Microbiology, CSU
Microbiology, CSU
CIAD, Hermosillo, Mexico
CIAD, Hermosillo, Mexico
2012-present
2014-present
2015-present
2015-present
2016-present
2016-present
M.S.
M.S.
Ph.D
Ph.D
Ph.D
Ph.D
Ph.D
Ph.D
Ph.D
Ph.D.
Ph.D.
UNIVERSITY SERVICE
Organizer, Administrator and Instructor of the Confocal Microsopy Unit at Colorado State
University 1998-2003.
FUNDING
Special Visiting Scientist Award, Science without Borders Program, CNPq Brazil
“Adaptation and Selection of Plasmodium falciparum Parasites by Anopheline Mosquito
Vectors from the New World”
8/1/2012-7/31/2015
Faculty Research Grant, Colorado State University
7/1/99-6/30/00
$ 4,500
College Research Council Grant, Colorado State University
7/1/99-6/30/00
$10,000
NIH-R01 Grant
“The Mosquito Immune Response and Malaria Transmission”
4/1/00-3/31/04
$1,011,220
EDITORIAL ACTIVITIES
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Member of the Editorial Board, PNAS 2014-2016
Member of the Advisory Board, Oncotarget, Immunology-Microbiology Section, since 2015
Member Editor, Proceedings of the National Academy of Sciences (PNAS) since 2014
Member of the Editorial Board, PloS ONE, since 2014
Associate Editor, PloS Genetics, since 2013
Member of the Editorial Advisory Board, Invertebrate Immunity, since 2012
Associate Editor, PloS Pathogens, since 2012
Referee, Cell, since 2010
Referee, Cell Host & Microbe, since 2010
Referee, BMC genomics, since 2010
Referee, PLoS Neglected Tropical Diseases, since 2008
Referee, PLoS One, since 2008
Referee, Biochimica et Biophysica Acta, since 2006
Referee, Science, since 2005
Referee, PLoS Pathogens, since 2005
Referee, Cellular Microbiology, since 2005
Referee, Free Radical Biology and Medicine, since 2005
Referee, European Journal of Biochemistry, since 2004
Referee, Journal of Parasitology, since 2004
Referee, Trends in Parasitology, since 2001
Referee, Proceedings of the National Academy of Sciences, U.S.A., since 2000
Referee, Gene, since 2000
Referee, Journal of Biological Chemistry, since 1999
Referee, Insect Biochemistry and Molecular Biology, since 1999
Referee, Insect Molecular Biology, since 1998
SOCIETY MEMBERSHIPS AND SERVICE
Councilor, American Committee of Medical Entomology of ASTMH, 2006-2010
Member, American Association for the Advancement of Science, since 1998
Member, American Society of Tropical Medicine and Hygiene, since 1998
Member, Sigma Xi, The Scientific Research Society, since 1987
Member, Guatemalan College of Medicine, since 1985
INTERNATIONAL ACTIVITES
Member
International Network of Science, Technology and Innovation.
National Council of Science and Technology, Guatemala.
Associate Researcher
Universidad del Valle de Guatemala
Instituto de Investigaciones
1999 - present.
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INTERNATIONAL VISITING SCIENTIST
Ana Paula Marques Duarte 2014
Laboratory of Medical Entomology,
Rene Rachou Institute, Fiocruz, Brazil
Lalita Gupta
2011
Birla Institute of Technology and Science (BITS),
Pilani, Rajasthan, India
Fábio Brayner dos Santos
2010
Centro de Pesquisas Aggeu Magalhães (Fiocruz),
Recife, Brazil.
Luiz Carlos Alves
2010
Centro de Pesquisas Aggeu Magalhães (Fiocruz),
Recife, Brazil.
Michael Povelones
2008
Imperial College, London, England.
Gustavo Ferreira Martins
2008
Kansas State Univ., Manhattan, KS.
Marco Neira Oviedo
2008
The Whitney Laboratory, St. Augustine, FL
Gloria Yepiz Plascencia
2004
Centro de Investigación en Alimentación y Desarrollo,
Hermosillo, México
FIELDS OF INTEREST
1. Interactions between Plasmodium parasites, the gut microbiota and mosquito midgut
epithelial cells.
2. Immune pathways that mediate antiplasmodial responses.
3. Hemocyte differentiation and immune memory in mosquitoes.
4. Plasmodium evasion of the mosquito immune system.
PUBLIC MEDIA AND INTERVIEWS
ScienceNews 2017
What a mosquito's immune system can tell us about fighting malaria
https://www.sciencenews.org/article/what-mosquitos-immune-system-can-tell-us-about-fighting-malaria
Medical Express 2017
New clue to how mosquitoes fend off malaria
https://medicalxpress.com/news/2017-01-clue-mosquitoes-fend-malaria.html
Profile of Carolina Barillas-Mury by Paul Gabrielsen 2015
http://www.pnas.org/content/112/5/1245.full.pdf
Sanofi-Pasteur Award Videos of Award Winners 2013
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https://www.youtube.com/watch?v=l5gBHm08sgY
Prensa Libre, Guatemala by Brenda Martinez, October 15, 2013
Carolina Barillas-Mury: “Con la ciencia saldremos adelante”
You can read the story at: https://issuu.com/prensalibregt/docs/plmt15102013
Correio Brazilense, Brasilia, Brasil by Thais de Luna 2012
Estudo contra a malária busca fortalecer o sistema imunológico do mosquito.
Your can read the report at: http://www.correiobraziliense.com.br/o-sistema-imunologico-do-mosquito
National Public Radio (NPR), Science Friday, host: Ira Flatow 2010
The Cure For Malaria Could Be In A Mosquito's Gut. You can listen to the story at:
http://www.npr.org/templates/story/story.php?storyId=129777523
Profiles in Tropical Medicine and Hygiene and Global Health 2010
You can read the interview at: http://www.astmh.org/news-events/in-the-news-old/barrillas-mury-profile
Science NOW by Dolly J. Krishnaswamy 2010
How mosquitoes Fight Malaria. You can read the story at:
http://news.sciencemag.org/health/2010/09/how-mosquitoes-fight-malaria
PATENTS FILED
Lead Inventor, U.S. Patent Application No. 62/463,011
Filed: February 24, 2017
“Compositions and Methods for Blocking Transmission of Plasmodium”
Lead Inventor, US patent No. 61/684,333
Filed: August 17, 2012
“Use of P47 from Plasmodium falciparum (Pfs47) or Plasmodium vivax (Pvs47) as a Vaccine
or Drug Screening Targets for the Inhibition of Human Malaria Transmission”
Lead Inventor, US patent No. 61/308,249
Filed: February 25, 2010
“Peroxidase and Peroxidase Substrate Peptides (PSPs) for Treatment of Inflammatory
Disorders and Allergies”
INVITED SPEAKER
NIH-University of Pennsylvania, Immunology Mini-course. Lecture: “What mosquitoes can
teach us about innate immunity”. NIH, Bethesda, January 2017
Plenary Speaker, II International ParaFrap Conference on Protozoan Pathogens, Les Embiez,
France, October, 2016
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INSERM Institute of Molecular and Cellular Biology, Strasbourg, France. Departmental
Seminar “Mosquito Immunity, Plasmodium immune evasion and Global Malaria
Transmission” October, 2016
Keynote Speaker at the XXVI International Congress of Entomology, Orlando, Florida,
“Mosquito Immunity and the Invisible Parasite: Implications for Global Malaria
Transmission”, September 2016
Keynote Speaker at the International Symposium entitled “Parasitology in the 21st century”
Pasteur Institute in Paris, France in November 2015
NIAID Bridging the Career Gap for Underrepresented Minority Scientists, NIH, “Plasmodium
Evasion of Mosquito Immunity and Global Malaria Transmission”, October 215
ASTMH 64th Annual Meeting, co-chair Scientific Session 61 Mosquitoes: Biochemistry and
Molecular Biology, “Molecular Mechanisms Mediating Innate Immune Priming in An.
gambiae mosquitoes”, Philadelphia, Pennsylvania, October, 2015.
XIV National Brazilian Meeting on Malaria Research. “Mosquito Immunity and Global
Malaria Transmission”, Sao Paulo, Brazil, September, 2015.
Centro de Pesquisa Gonçalo Moniz, Fiocruz-Bahia, “Plasmodium Evasion of Mosquito
Immunity and Global Malaria Transmission”, Salvador Bahia, Brazil, June 2015.
Federal University of Rio de Janeiro, “Plasmodium Evasion of Mosquito Immunity and Global
Malaria Transmission”, Rio de Janeiro, Brazil, June 2015.
Harvard School of Public Health, Departmental Seminar. “Mosquito Immunity and
Globalization of Malaria”, Boston, April, 2015
Gordon Research Conference on Tropical Infectious Diseases.
Global Malaria Transmission”, Galveston, Texas, March 2015
“Mosquito Immunity and
Johns Hopkins Malaria Research Institutes “Microbe-based malaria control”, “Mosquito
Immunity and the Invisible Parasite: Implications for Global Malaria Transmission”, Johns
Hopkins University, Rockville, Maryland, October 2014.
Laboratory of Parasitic Diseases (LPD), “Mosquito Immunity and the Invisible Parasite:
Implications for Global Malaria Transmission”, National Institutes of Health, Bethesda,
Maryland, October, 2014
Department of Veterinary Medicine Departmental Seminar, University of Maryland “Mosquito
Immunity and the Invisible Parasite: Implications for Global Malaria Transmission”,
College Park, Maryland, October, 2014.
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Sao Paulo University (USP), “Mosquito Immunity and the Invisible Parasite: Implications for
Global Malaria Transmission”, Sao Paulo, Brazil, September 2014.
Centro de Pesquisa Rene Rachou, Fiocruz-Mina Gerais, “Mosquito Immunity and the Invisible
Parasite: Implications for Global Malaria Transmission”, Brazil, September 2014.
13th International Congress on Parasitology (ICOPA), “Mosquito Defense Responses and
Plasmodium Immune Evasion: Implications for Global Malaria Transmission”, Mexico
City, Mexico, August 2014.
Keynote Speaker, 10th Annual BioMalPar I EVIMalaR Conference - Biology and Pathology
of the Malaria Parasite, “Mosquito Immunity and the Invisible Parasite: Implication for
Global Malaria Transmission”, EMBL, Heidelberg, Germany, May 2014.
Demystifying Medicine Lectures “Malaria: Origin and Advances in the World's Major Killer”,
National Institutes of Health, April, 2014
Keynote Speaker, ASTMH 62th Annual Meeting, ACME Symposium, “Mosquito Immunity
and Malaria Transmission: Insights into immune activation and Plasmodium immune
evasion”, Washington DC, November, 2013.
FNIH-NIAID Workshop on Population Replacement Strategies for Malaria Vectors.
Washington, November, 2013.
Institute Pasteur Sanofi-Pasteur Awards Symposium. “Mosquito Immunity and the in invisible
parasite: Implication for global malaria transmission”, Paris, France, November 2013.
Gordon Research Conference on Molecular and Cell Biology of Malaria, “Mosquito immune
activation and Plasmodium immune evasion”, Lucca, Italy, August, 2013.
Centro de Pesquisa Gonçalo Moniz, Fiocruz-Bahia, “Mosquito immune activation
and Plasmodium immune evasion”, Brazil, June, 2013.
Centro de Pesquisa Rene Rachou, Fiocruz-Mina Gerais, “Mosquito immune activation
and Plasmodium immune evasion”, Brazil, June, 2013.
I Workshop on Malaria Vectors in the Amazon, Fundação de Medicina Tropical Dr. Heitor
Vieira Dourado, “Mosquito Immunity and Malaria Transmission”, Manaus, AM, Brazil,
June, 2013.
Harvard School of Public Health, Departmental Seminar. “Malaria Transmission: a tale of
mosquito immune activation and Plasmodium immune evasion”, Boston, March, 2013.
Co-organizer and speaker in the Keystone Symposium on “Malaria” and Chair of the “Biology
of Plasmodium Transmission Stages” Session, New Orleans, January, 2013.
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Stockholm University, Frontiers in Molecular Life Sciences Lecture Series.
Immunity and Malaria Transmission”, Stockholm, September, 2012.
“Mosquito
GlaxoSmithKlein, Guest Seminar Speaker. “Mosquito Immunity and Malaria Transmission”,
Tres Cantos, Madrid, Spain, September, 2012.
Keynote Speaker, US-Brazil Vector Biology Meeting. “Plasmodium falciparum evasion of
the A. gambiae immune system” NIH Rocky Mountain Laboratories, Hamilton, Montana,
August, 2012.
XVI Arthromint Encounter. “Mosquito Immunity and Malaria Transmission”, Ihla Grande,
Rio de Janeiro, Brazil, August, 2012.
Radboud Summer Frontiers Symposium on Training the innate immunity: immunological
memory in innate host defense. “Innate Immune Memory in Mosquitoes”. Nijmegen, The
Netherlands, June 2012
Gordon Research Conference on Biology of Host-Pathogen, “Mosquito Immunity and Malaria
Transmission”. Newport RI, June 2012
Vector Encounter, Johns Hopkins University, “Plasmodium falciparum evasion of the A.
gambiae immune system”, Baltimore, July 2012.
Guest Lecturer, Molecular Entomology Course, Johns Hopkins University, Baltimore. “A.
gambiae immunity and malaria transmission”, May 2010.
ASTMH 60th Annual Meeting, Symposium 168 - Cellular Immunity in Mosquito-Pathogen
Interactions “Mosquito Immune Memory”, Philadelphia, December 2011.
Guest Speaker, European Virtual Institute For Malaria Research (EviMalaR) Clusters 1&3
Mini-Symposium: Genetics, Immunity And Vaccine Development Against Malaria.
“Mosquito Immunity and Malaria Transmission”, Barcelona, Spain, October 2011.
Department of Medicine, Departmental Seminar, “Mosquito Immunity and Malaria
Transmission”, University of Massachusetts Medical School, Worcester MA, September
2011.
EMBO Workshop on Molecular and Population Biology of Mosquitoes and Other Disease
Vectors, “Midgut epithelial nitration and complement activation in A. gambiae”
Kolymbari, Crete, Greece, July 2011.
Biology of Parasitism: Modern Approaches, Summer Course. “Mosquito Immune Responses
to Plasmodium Infection” and “Midgut epithelial nitration and complement activation in A.
gambiae”, Woods Hole, MA, July, 2011.
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Vector Encounter, Johns Hopkins University, “Epithelial Nitration and Complement
Activation in A. gambiae”, Baltimore, July 2011.
Institute for Integrative Genome Biology & Department of Entomology Seminar Series.
“Mosquito Immunity and Malaria Transmission”, University of California, Riverside, CA,
May, 2011.
XL Meeting of the Brazilian Society of Biochemistry and Molecular Biology. “Mosquito
epithelial responses to Plasmodium infection”, Foz de Iguazu, Brazil, May, 2011.
ASTMH 59th Annual Meeting, Symposium on Post-genomic Discoveries Leading the Way for
Disease Control “Identification of the gene(s) that allow Plasmodium falciparum to evade
the mosquito immune system”, Atlanta, Georgia, November, 2010.
XII National Brazilian Meeting on Malaria Research. “Interactions between Plasmodium
parasites, the gut microbiota and the immune system of A. gambiae mosquitoes”, Ouro
Preto, Brazil, October, 2010.
Biology of Parasitism: Modern Approaches, Summer Course. “Mosquito Immune Responses
that limit Plasmodium Infection” and “Innate Immune Memory in A. gambiae”, Woods
Hole, MA, July, 2010.
Global Health Institute, Ecole Polytechnique Fédérale de Lausanne, EPFL-GHI-SV-UPLEM,
“Plasmodium-mosquito interactions: A story of insect immune memory and parasite
immune evasion”, Lausanne, Switzerland, June 2010.
Guest Speaker at the Gordon Research Conference on Nox Family NADPH Oxidases:
Towards Understanding Nox/Duox Function: “Mosquito Duox and Nox interact with
midgut peroxidases and modulate Plasmodium infection” Les Diablerets, Switzerland,
June, 2010.
Guest Lecturer, Molecular Entomology Course, Johns Hopkins University, Baltimore. “An.
gambiae immune responses to Plasmodium infection”, May 2010.
Mosquito Biology and Biotechnology Conference, “Plasmodium-mosquito interactions”,
Duke University, North Carolina, December 2009
ASTMH 58th Annual Meeting, Symposium on Anopheles immunity to Plasmodium, “Can the
mosquito immune system learn from experience?” Washington D.C., December, 2009.
Catholic University of Leuven, Departmental Seminar, Department of Molecular and
Developmental Genetics, “Plasmodium-mosquito interactions: A story of insect immune
memory and parasite immune evasion”, Leuven, Belgium, September, 2009.
Free University of Brussels, Departmental Seminar, Laboratory of Molecular Parasitology,
“Plasmodium-mosquito interactions”, Gosselies, Belgium, September, 2009.
15
EMBO Workshop on Molecular and Population Biology of Mosquitoes and Other Disease
Vectors, “Immunological memory in A. gambiae: Can mosquitoes “learn” from a
challenge with Plasmodium?”, Kolymbari, Crete, Greece, July 2009.
Department of Entomology Seminar Series, University of Georgia. “Mosquito immune
responses to Plasmodium”, Athens, Georgia, March, 2009.
Intramural NIAID Research Opportunities (INRO) Program, Coordinator of the Symposium
on “Career Paths”. NIH, Twinbrook III Facility, Rockville, Maryland, February, 2009.
Guest Speaker at the Gordon Research Conference on Emergent/Re-Emergent Tropical
Diseases. “How does Plasmodium evade the mosquito’s immune system?” Galveston,
Texas, January, 2009.
ASTMH 57th Annual Meeting, Plasmodium-mosquito interactions symposium, “The STAT
pathway mediates late-phase immunity against Plasmodium oocysts”, New Orleans,
December, 2008.
Department of Biology Seminar Series, Florida International University, “Mosquito immune
responses to Plasmdoium and mechanisms of immune evasion”, Miami, Florida, November
2008.
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDKD) Departmental
Seminar Series, NIH Main Campus, Bethesda MD. “Mosquito-Plasmodium interactions”,
Bethesda, Maryland, October, 2008.
Universidad Rafael Landivar de Guatemala, Department of Medicine, “El estudio de la
immunidad innata en insectos ha revolucionado la immunologia medica”, Guatemala City,
Guatemala, July, 2008.
Universidad del Valle de Guatemala, Department of Biochemistry, “Mecanismos que le
permiten a Plasmodium evadir la respuesta immune del mosquito”, Guatemala City,
Guatemala, July 2008.
Plenary Speaker, Guatemalan National Council of Science and Technology,
CONVERCIENCIA 2008 Science Encounter, “Immunidad innata y la susceptibilidad a
infecciones”, Guatemala City, Guatemala, July, 2008.
Vector Encounter, Johns Hopkins University, “How does Plasmodium evade the mosquito’s
immune system?” Baltimore, July 2008.
Guest Speaker at the NCI/CCR/NIAID Symposium “Manipulation of Host Immune
Response”, NIH Campus, Bethesda, June 2008.
16
Guest Speaker, Guest speaker in the "World Malaria Day" Symposium. Center for Infectious
Disease and Mortara Center, Georgetown University. “Evasion of mosquito immune
responses by Plasmdoium falciparum”, Washington DC, April 2008.
Guest Lecturer, Molecular Entomology Course, Johns Hopkins University, “Defense
responses of An. gambiae midgut epithelial cells to Plasmodium infection”, Baltimore,
Maryland, April 2008.
Guest speaker at the Division of Biology Seminar Series, Kansas State University, “Anopheles
gambiae immune responses that determine susceptibility to Plasmodium infection”,
Manhattan, Kansas, March 2008.
Guest Speaker. International Malaria Research Conference, The Johns Hopkins University,
Baltimore, MD. “How do Plasmodium parasites evade the mosquito’s immune system?”
March, 2008.
Intramural NIAID Research Opportunities (INRO) Program, “Mosquito-parasite interactions
that affect human malaria transmission”. NIH, Twinbrook III Facility, Rockville,
Maryland, February, 2008
2007/2008 DIR Grand Rounds Seminar Series: “Immune Responses of An. gambiae that
determine susceptibility to Plasmodium infection”, Lipsett Auditorium, NIH Campus,
Bethesda, Maryland, December, 2008.
Invited Participant in the “Leadership and Gender Training for Women in the Health
Sciences in Latin America” Meeting, Stone House, NIH Campus, Bethesda, Maryland,
December 2007.
ASTMH 56th Annual Meeting, speaker and co-chair of the Vector Biology Session, “The
STAT pathway limits Plasmodium infection in An. gambiae, Philadelphia, November,
2007
10th International Union of Biochemistry and Molecular Biology (IUBMB) Conference,
Arthropod Immunity and Pathogen Transmission Symposium: “A. gambiae immune
responses limit Plasmodium infection”, Salvador, Brazil, May 2007.
Centro de Pesquisa Gonçalo Moniz, Fiocruz-Bahia, “An. gambiae responses to Plamodium
infection”, Brazil, May 2007.
Georgetown University School of Medicine, Department Biochemistry & Molecular Biology
Seminar Series. “A. gambiae immune responses to Plasmodium infection”, May 2007.
Guest Lecturer, Molecular Entomology Course, Johns Hopkins University, “Reactive Oxygen
Species modulate A. gambiae immune responses to Plasmodium infection”, Baltimore,
Maryland, April 2007.
17
11th International Congress on Parasitology (ICOPA), Co-chair of the Immune Responses in
Disease Vectors Session. “A secreted midgut peroxidase mediates refractoriness to
Plasmodium infection in A. gambiae, Glasgow, Scotland, August 2006.
10th International Congress of the International Society for Developmental and Comparative
Immunology, “The role of reactive oxygen species (ROS) on mosquito immune responses
to bacteria and Plasmodium”, “A secreted midgut peroxidase mediates refractoriness to
Plasmodium infection in A. gambiae, Charleston, South Carolina, July 2006.
The Fogarty International Center (FIC) and the Office of Research on Women’s Health
(ORWH). International Women’s Day Celebration, NIH, “A Tale of Female Mosquitoes,
Malaria in the Tropics, and Women in Science”, Bethesda, Maryland, March 2006.
Immunology Interest group Seminar Series, NIH, “The defense responses of mosquito midgut
epithelial cells limit Plasmodium infection”, Bethesda, Maryland, February 2006.
Laboratory of Parasitic Diseases Seminar Series, NIH, Bethesda. “Mosquito immune
responses that determine malaria transmission”, November 2005.
7th Biennial Bridging the Career Gap Workshop, Bethesda, Maryland. “My Career as an
Intramural NIH Researcher”. Office of Special Populations and Research Training, DEA,
NIAID, November 2005.
Immunology Seminar Series, Twinbrook II Facility, NIH, Rockville. “Anopheles gambiae
immune responses and malaria transmission”, October 2005.
EMBO Workshop on Molecular and Population Biology of Mosquitoes and Other Disease
Vectors, Kolymbari, Crete, Greece. “Two peroxidases mediate refractoriness in A.
gambiae”, July 2005.
Johns Hopkins University, Baltimore, Vector Encounter. “Midgut peroxidases mediate
refractoriness to Plasmodium in A. gambiae”, July 2005.
Guest Lecturer, Molecular Entomology Course, “Defense responses of migut epithelial cells
to Plasmodium invasion”, Johns Hopkins University, Baltimore, May 2005.
Keynote Speaker, Malaria Meeting, British Society for Parasitology, Mosquito Genome and
Vector Competence Section. “The role of midgut peroxidases in malaria ookinete survival
in anopheline mosquitoes”, Nottingham, UK, April 2005.
Penn State University, Department of Entomology, “The role of midgut peroxidases in
vectorial capacity of anopheline mosquitoes”, Philadelphia, March 2005.
Johns Hopkins University, “The role of midgut peroxidases in vectorial capacity of
anopheline mosquitoes”, Baltimore, Malaria Meeting, March 2005.
18
New York University, Department of Medical & Molecular Parasitology, “Inducible midgut
peroxidases mediate nitration of ookinete-invaded midgut cells in anophelines”, New York,
December 2004.
Johns Hopkins University, Vector Encounter,“Mosquito midgut epithelial responses in
different vector-parasite systems”, Baltimore, July 2004.
Centro de Investigaciones en Alimentación y Desarrollo (CIAD), “La nitracion y apoptosis de
las celulas intestinales de A. stephensi en respuesta a la invasion por ookinetos de P.
berghei es mediada por peroxidasas inducibles”, Hermosillo, México, April 2004.
Keystone Symposium, Genetic Manipulation of Insect Vectors, “Inducible peroxidases
mediate protein nitration and apoptosis of An. stephensi midgut cells in response to P.
berghei ookinete invasion”, Taos, New Mexico, February 2004.
Kansas State University, Department of Biochemistry, “The Role of Reactive Oxygen Species
(ROS) in the Melanotic Encapsulation Refractory Mechanism”, Manhattan, Kansas,
December 2003.
ASTMH Annual Meeting, "The role of Reactive Oxygen Species (ROS) on Plasmodium
melanotic encapsulation", Denver, Colorado, November 2002.
FASEB Research Conference on Microbial Pathogenesis: Mechanisms of Infectious Diseases,
“Cell biology and signal transduction pathways mediating midgut epithelial cell responses
to ookinete invasion”, Snowmass, Colorado, August 2002.
Gordon Research Conference on Parasitism,“Cell biology and signal transduction pathways
mediating midgut epithelial cell responses to ookinete invasion”, Salve Regina University,
Newport, Rhode Island, June 2002.
Laboratory of Parasitic Disease and Laboratory of Malaria and Vector Research, NIH, “Cell
biology of ookinete midgut invasion: elucidating the signal transduction pathways
mediating epithelial defense responses”, Bethesda, Maryland, January 2002.
V Annual Arthromint Encounter. Arthropod and Helminth Research, “La Immunidad de los
Insectos y los Receptores Toll”, “Herramientas Moleculares para el estudio de
Artropodos”, Caxambu, Mina Gerais, Brazil, November 2001.
Imperial College, Department of Biology, “Molecular interactions between ookinetes and
midgut epithelial cells, The Time Bomb Theory of ookinete invasion”, London, England,
June 2001.
19
International Course on the Biology of Disease Vectors, Plenary lectures: “Molecular
interactions between ookinetes and midgut epithelial cells, The Time Bomb Theory of
ookinete invasion”, “Modern Molecular Tools in Vector Biology” and “The Toll
Receptors and innate immunity in insects and vertebrates”, Ceske Budejovice, Czech
Republic, June 2001.
Universita' di Roma, Tor Vergata, Biology Department, “Molecular interactions between
ookinetes and midgut epithelial cells, The Time Bomb Theory of ookinete invasion”,
Rome, Italy, June 2001.
Centro de Investigaciones en Alimentación y Desarrollo (CIAD), “Interacciones entre los
oocinetos y las celulas del epitelio intestinal, La Teoria de la Bomba de Tiempo”,
Hermosillo, México, May 2001.
Keystone Symposium, Genetic Manipulation of Insect Vectors, “Midgut epithelium responses
to ookinete invasion”, Taos, New Mexico, February 2001.
International Course on the Biology of Disease Vectors, Colorado State University, Plenary
lectures: “Molecular interactions between ookinetes and midgut epithelial cells” and “The
Toll Receptors and innate immunity in insects and vertebrates”, Fort Collins, Colorado,
June 2000.
I Reunion Internacional del Biomed: Biologia de vectores y de los patogenos que ellos
transmiten. “Regulacion de la respuesta immune en insectos, implicaciones para la
capacidad vectorial en moquitos e immunidad innata en humanos” “Interacciones
Moleculares entre los oocinetos de Plasmodium y las celulas del epitelio intestinal: La
Teoria de la Bomba de Tiempo de la invasion del mosquito”, Maracay, Venezuela,
December 2000.
Centro de Pesquisas René Rachou-Fiocruz, “Interacciones entre los oocinetos y las celulas del
epitelio intestinal, La Teoria de la Bomba de Tiempo”, Belo Horizonte, Brazil. November
2000.
XVI Meeting of the Brazilian Society of Protozoology, “Molecular interactions between
ookinetes and midgut epithelial cells, The Time Bomb Theory of ookinete invasion”,
Caxambu, Brazil, November 2000.
Annual Meeting of the American Society of Tropical Medicine and Hygiene, Molecular
interactions between ookinetes and midgut epithelial cells, Houston, October 2000.
Institut de Biologie Moléculaire et Cellulaire, "The Time Bomb theory of ookinete invasion”,
Strasbourg, France, May 2000.
Leiden University Medical Centre, Department of Parasitology, “Responses of mosquito
midgut epithelial cells to ookinete invasion”, Leiden, The Netherlands, May 2000.
20
Entomological Society of America (ESA) Annual Meeting, “Activation of Ag-STAT in
response to infection in Anopheles gambiae”, Atlanta, Georgia, December 1999.
Gordon Research Conference on Parasitism, Salve Regina University, “Signaling pathways
and cell biology of mosquito immune responses to Plasmodium: If the vector responds,
why is parasite transmission still taking place?”, Newport, Rhode Island, June 1999.
Centro de Investigaciones en Alimentación y Desarrollo (CIAD), "Regulacion de la respuesta
inmune en el mosquito Anopheles gambiae”, Hermosillo, México, November 1998.
Third International Symposium on Molecular Insect Science, “Anopheles gambiae Ag-STAT,
a new insect member of the STAT family is activated in response to infection”, Snowbird,
Utah, June 1998.
Universidad del Valle de Guatemala, “Los factores de transcripcion rel y la respuesta immune
del mosquito Anopheles gambiae”, Guatemala City, Guatemala. December, 1996.
Stockholm University, Department of Molecular Biology and Department of Genetics,
"Immune response in A. gambiae; the first rel-family member is identified”, Stockholm,
Sweden, September 1995.
Institut de Biologie Moléculaire et Cellulaire, "Immune response in An. gambiae and Relfamily members", Strasbourg, France, November 1994.
Annual Meeting of the American Society of Tropical Medicine and Hygiene, Symposium on
Biology of Disease Vectors, "Proteolytic enzymes of insect vectors", Seattle, November
1992.
MacArthur Network on the Biology of Parasite Vectors, Scientific Institute, "Molecular
characterization of a blood-meal induced trypsin from the mosquito Aedes aegypti", Santa
Cruz, California. April 1992.
IX Aniversary Lectures, Centro de Investigaciones en Alimentación y Desarrollo (CIAD),
"Caracterización de una tripsina del mosquito Aedes aegypti inducible mediate la ingesta de
sangre", Hermosillo, México, March 1991.
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42. DeJong R.J., Miller L.M., Molina-Cruz A., Gupta L., Kumar S., Barillas-Mury C. (2007)
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43. Noh MY, Jo YH, Oh SH, Dong HK, Park HJ, Kim I, Barillas-Mury C. et al. (2006)
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44. Gomez-Anduro G.A., Barillas-Mury C., Peregrino-Uriarte A.B., Gupta L., Gollas-Galvan
T., Hernandez-Lopez J., Yepiz-Plascencia G. (2006) The cytosolic manganese superoxide
dismutase from the shrimp Litopenaeus vannamei: Molecular cloning and expression. Dev
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45. Barillas-Mury C. and Kumar S. (2005) Plasmodium-mosquito interactions: a tale of
dangerous liaisons. Cell Microbiol. 7(11):1539-45.
46. Gupta L., Kumar S., Han Y.S., Pimenta P.F. and Barillas-Mury C. (2005) Midgut
epithelial responses in different mosquito-Plasmodium combinations: the Actin Cone
Zipper Model of epithelial repair in Aedes Aegypti. Proc. Nat.l Acad. Sci. U S A
102(11):4010-5.
47. Molina-Cruz A., Gupta L., Richardson J., Bennett K., Black IV W. and Barillas-Mury, C.
(2005) Effect of mosquito midgut trypsin activity on dengue-2 virus infection and
dissemination in Aedes aegypti. Am. J. Trop. Med. Hyg. 72(5):631-7.
48. Kumar S. and Barillas-Mury C. (2005) Ookinete-induced midgut peroxidases detonate the
Time Bomb in anopheline mosquitoes. Insect Biochem. Molec. Biol. 35(7):721-7.
49. Barillas-Mury C., Paskewitz S. and Kanost M.R. (2005) Immune Responses of Vectors.
In: The Biology of Disease Vectors, Second Edition. Editors: WC Marquardt, WC Black, J
Freier, H Hagedorn, J Hemingway, S Higgs, AA James and B Kondratieff. Elsevier
Science. pp. 363-376.
50. Kumar S, Gupta L, Han YS, Barillas-Mury C. (2004) Inducible peroxidases mediate
nitration of Anopheles midgut cells undergoing apoptosis in response to Plasmodium
invasion. J Biol Chem. 279:53475-82.
51. Danielli A., Barillas-Mury C., Kumar S, Kafatos F.C. and Loukeris T.G. (2004)
Overexpression and altered nucleocytoplasmic distribution of Anopheles ovalbumin-like
SRPN10 Serpins in Plasmodium infected midgut cells. Cellular Microbiology 7(2):181190.
52. Kamhawi S, Ramalho-Ortigao M, Pham VM, Kumar S, Lawyer PG, Turco SJ, BarillasMury C, Sacks DL, Valenzuela JG. (2004) A role for insect galectins in parasite survival.
Cell. 119(3):329-41.
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53. Tavares-Sanchez OL, Gomez-Anduro GA, Felipe-Ortega X, Islas-Osuna MA, SoteloMundo RR, Barillas-Mury C, Yepiz-Plascencia G (2004) Catalase from the white shrimp
Penaeus (Litopenaeus) vannamei: molecular cloning and protein detection. Comp Biochem
Physiol B Biochem Mol Biol. 138(4):331-7
54. Kumar S., Christophides G.K., Cantera R., Charles B., Han Y.H., Meister S., Dimopoulos
G., Kafatos F.C. and Barillas-Mury C. (2003) The role of Reactive Oxygen Species
(ROS) on Plasmodium melanotic encapsulation in Anopheles gambiae. Proc. Nat.l Acad.
Sci. U S A 100(24): 14139-14144.
55. Zdobnov EM, von Mering C, Letunic I, Torrents D, Suyama M, Copley RR, Christophides
GK, Thomasova D, Holt RA, Subramanian GM, Mueller HM, Dimopoulos G, Law JH,
Wells MA, Birney E, Charlab R, Halpern AL, Kokoza E, Kraft CL, Lai Z, Lewis S, Louis
C, Barillas-Mury C, Nusskern D, Rubin GM, Salzberg SL, Sutton GG, Topalis P, Wides
R, Wincker P, Yandell M, Collins FH, Ribeiro J, Gelbart WM, Kafatos FC, Bork P. (2002)
Comparative genome and proteome analysis of Anopheles gambiae and Drosophila
melanogaster. Science, 298(5591):149-59
56. Christophides GK, Zdobnov E, Barillas-Mury C, Birney E, Blandin S, Blass C, Brey PT,
Collins FH, Danielli A, Dimopoulos G, Hetru C, Hoa NT, Hoffmann JA, Kanzok SM,
Letunic I, Levashina EA, Loukeris TG, Lycett G, Meister S, Michel K, Moita LF, Muller
HM, Osta MA, Paskewitz SM, Reichhart JM, Rzhetsky A, Troxler L, Vernick KD,
Vlachou D, Volz J, von Mering C, Xu J, Zheng L, Bork P, Kafatos FC. (2002) Immunityrelated genes and gene families in Anopheles gambiae. Science. 298(5591):159-65.
57. Han, Y.S. and Barillas-Mury, C. (2002) Implications of the Time Bomb model of
ookinete invasion of midgut cells. Insect Biochem. Molec. Biol. 32(10): 1311-1316.
58. Dimopoulos, G., Christophides, G.K., Meister, S., Schultz, J., White, K.P., Barillas-Mury,
C. and Kafatos, F.C. (2002) Genome expression analysis of Anopheles gambiae: responses
to injury, bacterial challenge, and malaria infection. Proc. Nat.l Acad. Sci. U S A. 99(13):
8814-9.
59. Black, W.C. 4th, Bennett, K.E., Gorrochotegui-Escalante, N., Barillas-Mury, C.,
Fernandez-Salas, I., de Lourdes Munoz, M., Farfan-Ale, J.A., Olson, K.E. and Beaty, B.J.
(2002) Flavivirus susceptibility in Aedes aegypti. Arch. Med. Res. 33(4):379-88.
60. Sigurdson, C.J., Barillas-Mury, C., Miller, M.W., Oesch, B., van Keulen, L.J.M.,
Langeveld, J.P.M. and Hoover, E.A. (2002) PrPCWD lymphoid cell targets in early and
advanced chronic wasting disease of mule deer. J Gen Virol 83: 2617-2628.
61. Han, Y.S., Thompson, J., Kafatos, F.C., Barillas-Mury, C. (2000) Molecular interactions
between Anopheles stephensi midgut cells and Plasmodium berghei: the time bomb theory
of ookinete invasion of mosquitoes. EMBO J. 19(22):6030-6040.
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62. Barillas-Mury, C., Wizel, B. and Han Y.S. (2000) Mosquito immune responses and
malaria transmission: lessons from insect model systems and implications for vertebrate
innate immunity and vaccine development. Insect Biochem. Molec. Biol. 30, 429-442.
63. Cramer, P., Varrot, A., Barillas-Mury, C., Kafatos, F. C. and Muller, C. W. (1999)
Structure of the specificity domain of the Dorsal homologue Gambif1 bound to DNA.
Structure 7(7), 841-852.
64. Barillas-Mury, C., Han Y.S., Seeley, D. C. & Kafatos, F. C. (1999). Anopheles gambiae
Ag-STAT, a new insect member of the STAT family is activated in response to bacterial
infection. EMBO J. 18: 959-967.
65. Cantera, R., Kozlova, T., Barillas-Mury, C. & Kafatos, F. C. (1999). Muscle structure and
innervation are affected by loss of dorsal in the fruit fly, Drosophila melanogaster. Mol
Cell Neurosci 13(2), 131-41.
66. Thompson, J., Richman, A., Barillas-Mury, C., Dimopoulos, G., Loukeris, T.G., Müller,
H.-M., Wang, R., Zheng, L., Kafatos F.C. (1998) Immune responses of Anopheles gambiae
and mosquito/parasite interactions. In: "Strategies for Microbial Persistence" contributions
from Nobel Symposium 106 on "Intracellular and Persistent Infections" June 7-10, 1998.
67. Charlesworth A., Georgieva T., Gospodov I., Law J.H., Dunkov B.B., Ralcheva N.,
Barillas-Mury C., Ralchev K. and Kafatos F.C. (1997) Isolation and properties of
Drosophila melanogaster ferritin, molecular cloning of a cDNA that encodes one subunit,
and localization of the gene on the third chromosome. Eur. J. Biochem 247: 470-475.
68. Barillas-Mury C., Charlesworth A., Gross I., Richman A., Hoffmann J.A. and Kafatos
F.C. (1996) Immune factor Gambif1, a New rel-Family Member from the Human Malaria
Vector, Anopheles gambiae. EMBO J. 15: 4691-4701.
69. Richman A.M., Bulet P., Hetru C., Barillas-Mury C., Hoffmann J.A. and Kafatos F.C.
(1996) Inducible immune factors of the vector mosquito Anopheles gambiae: biochemical
purification of a Defensin antibacterial peptide and molecular cloning of preprodefensin
cDNA. Insect Molec. Biol. 5, 203-210.
70. Noriega F.G., Wang X-Y., Pennington J.E., Barillas-Mury C. and Wells M.A. (1996)
Early trypsin, a female-specific midgut protease in Aedes aegypti: isolation, amino-terminal
sequence determination and cloning and sequencing of the gene. Insect Biochem. Molec.
Biol. 26: 119-126.
71. Noriega F.G., Pennington J.E., Barillas-Mury C., Wang X-Y. and Wells M.A. (1996)
Aedes aegypti midgut early trypsin is post-transcriptionally regulated by blood feeding.
Insect Molec. Biol. 5: 25-29.
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72. Barillas-Mury C., Noriega F.G. and Wells M.A. (1995) Early trypsin activity is part of the
signal transduction system that activates transcription of the late trypsin gene in the midgut
of the mosquito, Aedes aegypti. Insect Biochem. Molec. Biology. 25: 241-246.
73. Peterson A.M., Barillas-Mury C. and Wells M.A. (1994) Sequence of three cDNAs
enconding an alkaline midgut trypsin from Manduca sexta. Insect Biochem. Molec. Biol.
24: 463-471.
74. Noriega F.G., Barillas-Mury C. and Wells M.A. (1994) Dietary control of late trypsin
gene transcription in Aedes aegypti. Insect Biochem. Molec. Biol. 24: 627-631.
75. Barillas-Mury C. and Wells M.A. (1993) Cloning and sequencing of the blood mealinduced late trypsin gene from the mosquito Aedes aegypti and characterization of the
upstream regulatory region. Insect Molec. Biol. 2: 7-12.
76. Lin Y., Hamblin M.T., Edwards MJ, Barillas-Mury C., Kanost M.R., Knipple D.C.
Wolfner M.F. and Hagedorn H.H. (1993) Structure, expression and hormonal control of
genes from the mosquito, Aedes aegypti, which encode proteins similar to the vitelline
membrane proteins of Drosophila melanogaster. Developmental Biology. 155: 558-568
77. Yonggu L., Hamblin M.T., Edwards M.J., Barillas-Mury C., Kanost M.R., Knipple D.C.,
Wolfner M.F. and Hagedorn H.H. (1993) Structure, expression and hormonal control of
genes from the mosquito, Aedes aegypti, which encode proteins similar to the vitelline
membrane proteins of Drosophila melanogaster. Developmental Biology 31: 558-568.
78. Barillas-Mury C. (1992) Molecular characterization of a blood-meal induced trypsin from
the mosquito Aedes aegypti. Doctoral Dissertation.
79. Rivera M., Barillas-Mury C., Christensen K.A., Little J.W., Wells M.A. and Walker F.A.
(1992) Gene Synthesis, Bacterial Expression and 1H NMR Spectroscopic Studies of the
Rat Outer Mitochondrial Membrane Cytochrome b5. Biochemistry 31: 12233-12240.
80. Vettorazzi C., Canales D., Rosales F., Barillas-Mury C, Van Woert J., Pineda O. and
Solomons N.W. (1992) Milk, lactose and ethanol as dietary factors in cataractogenesis in
Guatemala. A case-control study. Int J Food Sci Nutr 43 (3): 155-162.
81. Barillas-Mury C., Graf R., Hagedorn H.H. and Wells M.A. (1991) cDNA and deduced
amino acid sequence of a blood meal-induced trypsin from the mosquito, Aedes aegypti.
Insect Biochem. 21: 825-831.
82. Barillas-Mury C. and Solomons N.W. (1987) Effective reduction of lactose malabsorption
in preschool children by direct addition of ß-galactosidases to milk at mealtime. Pediatrics
79: 776-772.
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83. Barillas-Mury C. and Solomons N.W. (1987) Variance in fasting breath hydrogen
concentrations in Guatemalan preschool children. J. Pediatr. Gastroenterol. Nutr. 6: 109113.
84. Barillas-Mury C. and Solomons N.W. (1987) Test-retest reproducibility of an abbreviated
breath-hydrogen test for survey studies in preschool children. J. Pediatr. Gastroenterol.
Nutr. 6: 281-285.
85. Barillas-Mury C., Vettorazzi C., Molina S. and Pineda O. (1987) Experience with
bioelectrical impedance determinations in young children: sources of variability.
Proceedings of the International Symposium on in vivo Body Composition Studies. London,
IPSM Publications, pp. 87-90.
86. Guzman M.J., Elsen R., Padilla A., Solomons N.W., Whalen C., Siu M.L., Mazariegos M.,
Molina S., Neufeld L., Rosas A., Barillas-Mury C, Canales D., Vettorazzi C., Beltranena
F. and Pineda O. (1987) Body composition determinations by bioelectrical impedance in
olympic-class athletes at the Third Central American Games. Proceedings of the
International Symposium on in vivo Body Compositon Studies. London, IPSM Publications,
pp. 100-104.
87. Solomons N.W. and Barillas-Mury C. (1986) The cut-off criterion for a positive hydrogen
breath test in children: a reppraisal. J. Pediatr. Gastroenterol. Nutr. 5: 920-925.
88. Barillas-Mury C. (1985) Efecto de dos ß-galacosidasas de origen microbiano sobre la
digestion de lactosa dietética en niños pre-escolares. Faculty of Medicine Graduation
Thesis.
89. Vasquez L., Barillas-Mury C. and Torún B. (1983) Prevalencia de malabsorción de dosis
dietéticas de lactosa en niños pre-escolares guatemaltecos. Informe anual INCAP, Pub. V76: 119-121.
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