ICD-10
CODE GUIDE
These codes are provided for reference and this list does not contain all possible applicable codes.
Codes should be chosen based on the patient’s relevant family and personal history and multiple
codes may be selected.
Bladder/Renal
ICD-10 Code
Code Description
C64.9
Malignant neoplasm of unspecified kidney, except renal pelvis
C65.9
Malignant neoplasm of unspecified renal pelvis
C66.9
Malignant neoplasm of unspecified ureter
C67.9
Malignant neoplasm of bladder, unspecified
C68.9
Malignant neoplasm of urinary organ, unspecified
D09.0
Carcinoma in situ of bladder
D09.10
Carcinoma in situ of unspecified urinary organ
D09.19
Carcinoma in situ of other urinary organs
Z80.51
Family history of malignant neoplasm of kidney
Z80.52
Family history of malignant neoplasm of bladder
Z80.59
Family history of malignant neoplasm of other urinary tract organ
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.50
Personal history of malignant neoplasm of unspecified urinary tract organ
Z85.51
Personal history of malignant neoplasm of bladder
Z85.520
Personal history of malignant carcinoid tumor of kidney
Z85.528
Personal history of other malignant neoplasm of kidney
Z85.53
Personal history of malignant neoplasm of renal pelvis
Z85.54
Personal history of malignant neoplasm of ureter
Z85.59
Personal history of malignant neoplasm of other urinary tract organ
ICD-10 Code
Breast / Ovarian
Code Description
C50.919
Malignant neoplasm of unspecified site of unspecified female breast
C50.929
Malignant neoplasm of unspecified site of unspecified male breast
C56.9
D05.00
Malignant neoplasm of unspecified ovary
Lobular carcinoma in situ of unspecified breast
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Breast / Ovarian continued
D05.10
Intraductal carcinoma in situ of unspecified breast
D05.90
Unspecified type of carcinoma in situ of unspecified breast
D07.30
Carcinoma in situ of unspecified female genital organs
Z15.01
Genetic susceptibility to malignant neoplasm of breast
Z15.02
Genetic susceptibility to malignant neoplasm of ovary
Z15.03
Genetic susceptibility to malignant neoplasm of prostate
Z80.3
Family history of malignant neoplasm of breast
Z80.41
Family history of malignant neoplasm of ovary
Z80.42
Family history of malignant neoplasm of prostate
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.3
Personal history of malignant neoplasm of breast
Z85.43
Personal history of malignant neoplasm of ovary
Colorectal
ICD-10 Code
C18.9
Code Description
Malignant neoplasm of colon, unspecified
C19
Malignant neoplasm of rectosigmoid junction
C20
Malignant neoplasm of rectum
C21.0
Malignant neoplasm of anus, unspecified
D01.0
Carcinoma in situ of colon
D01.1
Carcinoma in situ of rectosigmoid junction
D01.2
Carcinoma in situ of rectum
D01.3
Carcinoma in situ of anus and anal canal
D01.40
Carcinoma in situ of unspecified part of intestine
D01.7
Carcinoma in situ of other specified digestive organs
D01.9
Carcinoma in situ of digestive organ, unspecified
K63.5
Polyp of colon
Z80.0
Family history of malignant neoplasm of digestive organs
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Colorectal continued
Z83.71
Family history of colonic polyps
Z83.79
Family history of other diseases of the digestive system
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.00
Personal history of malignant neoplasm of unspecified digestive organ
Z86.010
Personal history of colonic polyps
Endocrine
ICD-10 Code
Code Description
C70.0
Malignant neoplasm of cerebral meninges
C70.1
Malignant neoplasm of spinal meninges
C70.9
Malignant neoplasm of meninges, unspecified
C73
Malignant neoplasm of thyroid gland
C75.0
Malignant neoplasm of parathyroid gland
C75.1
Malignant neoplasm of pituitary gland
C75.9
Malignant neoplasm of endocrine gland, unspecified
D09.3
Carcinoma in situ of thyroid and other endocrine glands
D17.9
Benign lipomatous neoplasm, unspecified
D34
Benign neoplasm of thyroid glands
D35.9
Benign neoplasm of endocrine gland, unspecified
D42.9
Neoplasm of uncertain behavior of meninges, unspecified
E21.5
Disorder of parathyroid gland, unspecified
E23.7
Disorder of pituitary gland, unspecified
Z15.81
Genetic susceptibility to multiple endocrine neoplasia [MEN]
Z83.41
Family history of multiple endocrine neoplasia [MEN] syndrome
Z83.49
Family history of other endocrine, nutritional and metabolic diseases
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.850
Personal history of malignant neoplasm of thyroid
Z85.858
Personal history of malignant neoplasm of other endocrine glands
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Endometrial / Uterine
ICD-10 Code
Code Description
C18.9
Malignant neoplasm of colon, unspecified
C54.1
Malignant neoplasm of endometrium
C55
Malignant neoplasm of uterus, part unspecified
C56.9
Malignant neoplasm of unspecified ovary
D07.0
Carcinoma in situ of endometrium
Z15.04
Genetic susceptibility to malignant neoplasm of endometrium
Z80.0
Family history of malignant neoplasm of digestive organs
Z80.3
Family history of malignant neoplasm of breast
Z80.41
Family history of malignant neoplasm of ovary
Z80.49
Family history of malignant neoplasm of other genital organs
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.00
Personal history of malignant neoplasm of unspecified digestive organ
Z85.3
Personal history of malignant neoplasm of breast
Z85.43
Personal history of malignant neoplasm of ovary
Z85.44
Personal history of malignant neoplasm of other female genital organs
Gastric
ICD-10 Code
Code Description
C15.9
Malignant neoplasm of esophagus, unspecified
C16.9
Malignant neoplasm of stomach, unspecified
C17.9
Malignant neoplasm of small intestine, unspecified
D00.1
Carcinoma in situ of esophagus
D00.2
Carcinoma in situ of stomach
D05.90
Unspecified type of carcinoma in situ of unspecified breast
Z80.0
Family history of malignant neoplasm of digestive organs
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.00
Personal history of malignant neoplasm of unspecified digestive organ
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Li-Fraumeni
ICD-10 Code
Code Description
C41.9
Malignant neoplasm of bone and articular cartilage, unspecified
C49.9
Malignant neoplasm of connective and soft tissue, unspecified
C50.919
Malignant neoplasm of unspecified site of unspecified female breast
C50.929
Malignant neoplasm of unspecified site of unspecified male breast
C71.9
Malignant neoplasm of brain, unspecified
C74.90
Malignant neoplasm of unspecified part of unspecified adrenal gland
D05.00
Lobular carcinoma in situ of unspecified breast
D05.10
Intraductal carcinoma in situ of unspecified breast
D05.90
Unspecified type of carcinoma in situ of unspecified breast
D09.8
Carcinoma in situ of other specified sites
D43.2
Neoplasm of uncertain behavior of brain, unspecified
D43.4
Neoplasm of uncertain behavior of spinal cord
Z85.830
Personal history of malignant neoplasm of bone
Lynch
ICD-10 Code
Code Description
C15.9
Malignant neoplasm of esophagus, unspecified
C16.9
Malignant neoplasm of stomach, unspecified
C17.9
Malignant neoplasm of small intestine, unspecified
C18.9
Malignant neoplasm of colon, unspecified
C25.9
Malignant neoplasm of pancreas, unspecified
C54.1
Malignant neoplasm of endometrium
D01.0
Carcinoma in situ of colon
D07.0
Carcinoma in situ of endometrium
D07.30
Carcinoma in situ of unspecified female genital organs
Z80.0
Family history of malignant neoplasm of digestive organs
Z80.41
Family history of malignant neoplasm of ovary
Z85.00
Personal history of malignant neoplasm of unspecified digestive organ
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Lynch continued
Z85.07
Personal history of malignant neoplasm of pancreas
Z85.43
Personal history of malignant neoplasm of ovary
Melanoma
ICD-10 Code
Code Description
C25.9
Malignant neoplasm of pancreas, unspecified
C43.9
Malignant melanoma of skin, unspecified
D01.7
Carcinoma in situ of other specified digestive organs
D01.9
Carcinoma in situ of digestive organ, unspecified
D03.9
Melanoma in situ, unspecified
D04.9
Carcinoma in situ of skin, unspecified
Z80.0
Family history of malignant neoplasm of digestive organs
Z80.8
Family history of malignant neoplasm of other organs or systems (skin, melanoma)
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.820
Personal history of malignant melanoma of skin
Pancreatic
ICD-10 Code
Code Description
C25.9
Malignant neoplasm of pancreas, unspecified
C80.1
Malignant (primary) neoplasm, unspecified (adenocarcinoma)
D01.7
Carcinoma in situ of other specified digestive organs (pancreas)
D01.9
Carcinoma in situ of digestive organ, unspecified
Z80.0
Family history of malignant neoplasm of digestive organs
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.07
Personal history of malignant neoplasm of pancreas
Prostate
ICD-10 Code
C61
D07.5
Code Description
Malignant neoplasm of prostate
Carcinoma in situ of prostate
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Prostate continued
R97.2
Elevated prostate specific antigen [PSA]
Z15.02
Genetic susceptibility to malignant neoplasm of ovary
Z15.03
Genetic susceptibility to malignant neoplasm of prostate
Z80.41
Family history of malignant neoplasm of ovary
Z80.42
Family history of malignant neoplasm of prostate
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Z85.46
Personal history of malignant neoplasm of prostate
Single Site
ICD-10 Code
Code Description
Z15.01
Genetic susceptibility to malignant neoplasm of breast
Z15.02
Genetic susceptibility to malignant neoplasm of ovary
Z15.03
Genetic susceptibility to malignant neoplasm of prostate
Z15.09
Genetic susceptibility to other malignant neoplasm
Z15.81
Genetic susceptibility to multiple endocrine neoplasia [MEN]
Z15.89
Genetic susceptibility to other disease
Z84.81
Family history of carrier of genetic disease (includes at risk for heritable disorder based on family
history, family history of gene mutation, family history of hereditary disease etc)
Other
ICD-10 Code
Code Description
D09.9
Carcinoma in situ, unspecified
Z80.8
Family history of malignant neoplasm of other organs or systems
Z80.9
Family history of malignant neoplasm, unspecified
Z85.89
Personal history of malignant neoplasm of other organs and systems
Z85.9
Personal history of malignant neoplasm, unspecified
Reference: www.icd10data.com/ICD10CM/Codes
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