Cattle have more
to gain from DECTOMAX®
and VALBAZEN®.
Important Safety Information:
DECTOMAX® Injectable has a 35-day
pre-slaughter withdrawal period.
DECTOMAX Pour-On has a 45-day
pre-slaughter withdrawal period. Do
not use in dairy cows 20 months of
age or older. DECTOMAX has been
developed specifically for cattle
and swine. Use in dogs may result
in fatalities. With VALBAZEN®, cattle
must not be slaughtered within 27
days after the last treatment. Not
for use in lactating dairy cattle. Do
not administer to female cattle
during the first 45 days of pregnancy
or for 45 days after removal of bulls.
Lawrence JD. Economic analysis of pharmaceutical
technologies in modern beef production in bioeconomy
era. Iowa State University. 2007. Available at: http://www.
econ.iastate.edu/faculty/Lawrence/documents/GET7401LawrencePaper.pdf. Accessed Aug. 9, 2010.
2
Data on file. Study Report Nos. 2839A-60-94-050 and
2839A-60-95-051, Pfizer Inc.
3
Vercruysse J, Rew RS. Macrocyclic lactones in antiparasitic
therapy. Pennsylvania: CABI Publishing, 2002;31-146.
4
Lifschitz A, et al. Distribution of endectocide compounds to
target tissues in cattle, in Proceedings. 43rd Annual Meeting
of Amer Assoc Vet Parasitologists 1998;43-59.
5
When comparing cattle plasma profiles.
6
DECTOMAX and other products noted. Freedom of
Information summaries.
7
Data on file. Study Report No. 2239A-60-94-068, 2239A-6092-027, 2239A-60-94-067, 2239A-60-95-156, 2839A-60-95156, 2839A-60-00-025, 2239A-60-00-030, 2230A-60-97-158,
2239A-60-00-033, 2839A-60-97-123, 2239A-60-00-029,
2239A-60-94-007, 2239A-60-94-070, 2239B-60-95-047,
2239B-60-96-063, 2239B-60-97-029, 2239B-60-96-212,
2239B-60-97-020, 2239A-60-97-053, Pfizer Inc.
8
Data on file, Study Report No. 2339D-02-003D, Pfizer Inc.
9
Gayrard V. Alvinerie M, Toutain PL. Comparison of
pharmacokinetic profiles of doramectin and ivermectin
pour-on formulations in cattle. Vet Parasitol 1998;81:47-55.
1
All brands are the property of their respective owners.
©2011 Pfizer Inc. All rights reserved. DMX10011
Powerful parasite control for a b
The economic losses from parasite infections can
really add up. Even moderate parasite burdens
can diminish productivity. The brown stomach
worm (Ostertagia ostertagi), for example, can
damage the digestive tract and cause appetite
suppression. The problem is exacerbated by
the small intestinal roundworm (Cooperia spp.),
which causes further destruction and prevents
proper nutrient absorption.
Other detrimental parasites include the
stomach worm (Haemonchus placei), the
nodule worm (Oesophagostomum radiatum)
and the lungworm (Dictyocaulus viviparus).
These parasites can result in significant
losses from poor weight gain, impaired feed
conversion and increased disease. And infected
cattle can contaminate pastures, spreading
parasites to other cattle.
Deworming lowers the cost of production
Cattle operations continue to earn a rising return
on investment for deworming, with $201/head
Administration and dosing
Administer DECTOMAX Injectable solution at the
recommended dosage of 1 mL (10 mg doramectin)
per 110 pounds body weight by subcutaneous (SC)
or intramuscular (IM) injection in the neck region.
SC injection is recommended to minimize the risk of
injection-site blemishes and is in accordance with
Beef Quality Assurance guidelines.
DECTOMAX Pour-On solution should be applied
topically along the mid-line of the back in a narrow
strip between the withers and tailhead, at the
recommended dosage of 1 mL (5 mg doramectin)
per 22 pounds body weight (or 10 mL/220 pounds
body weight).
VALBAZEN should be administered to cattle at the
recommended rate of 4 mL/100 pounds of body
weight (equivalent to 4.54 mg of albendazole/
pound, 10 mg/kg).
Best time to treat.
etter return on your investment.
for cow/calf operators and $24/head for stocker
operations.1
Heavier cattle, better profits
DECTOMAX® (doramectin) and VALBAZEN®
(albendazole) provide long-lasting control that
eliminates the toughest parasites, and protects
your bottom line.
With DECTOMAX®
• At weaning in cow/calf operations
• At arrival at stocker facilities
• Spring to reduce pasture
contamination
With VALBAZEN®
• At weaning in cow/calf operations
• At arrival at feeding facilities
• When adult liver flukes are most
prevalent
– Winter in Northern regions
– Summer in Southern regions
With fewer worms, cattle experience improved
appetite and greater weight gain. In comparison
studies under different levels of parasite burdens,
cattle treated with DECTOMAX showed greater final
body weights.2 That adds up to more profitable
cattle and higher-quality carcasses.
Powerful and effective
DECTOMAX offers up to 28 days of protection
against the most damaging internal parasites, giving
you powerful control over more parasite stages,
including immatures, for longer periods of time.
For liver fluke-endemic areas, VALBAZEN delivers
effective control of liver flukes and internal parasites.
DECTOMAX® 1% Injectable: Targ control, including liver flukes.
DECTOMAX® Injectable delivers greater
therapeutic effectiveness against internal
parasites, putting more killing power directly
into the bloodstream, for faster delivery to
the site of worm infections.3,4
The broadest range of parasite
control available.
No other single injectable product controls
a broader spectrum of internal and external
parasites than DECTOMAX. It knocks out
36 stages of adult parasites, L 4 larvae and
inhibited larvae.
Product label comparison
Parasite
VALBAZEN
Suspension
(10 mg/kg)
Fasciola hepatica, Adult
X
Moniezia benedeni
X
M. expansa
X
Ostertagia ostertagi, Adult
X
O. ostertagi, L4 , inhibited L4
X
Haemonchus contortus, Adult, L4
X
Safe-Guard®
Suspension
(5 mg/kg)
X
X
H. placei, Adult, L4
X
X
Internal parasites controlled in cattle:
Trichostrongylus axei, Adult, L4
X
X
• Gastrointestinal roundworms
• Lungworms
• Eyeworms
Nematodirus spathiger, Adult, L4
X
External parasites controlled in cattle:
• Grubs
• Sucking lice
• Mange mites
X
X
X
X
C. oncophora, Adult, L4
X
X
Bustomum phlebotomum, Adult
X
X
X
B. phlebotomum, L4
Label comparisons:
Length of protection from reinfection
DECTOMAX
Injectable
Ivomec®
Injectable
Cydectin®
Injectable
Ostertagia ostertagi
(brown stomach worm)
21 days
21 days
14 days
Cooperia oncophora
(small intestinal worm)
14 days
14 days
0 days
C. punctata
(small intestinal worm)
28 days
14 days
0 days
Parasite
N. helvetianus, Adult, L4
Cooperia punctata, Adult, L4
T richostrongylus colubriformis,
Adult
X
X
T. colubriformis, L4
esophagostomum radiatum,
O
Adult
X
X
X
X
O. radiatum, L4
Dictyocaulus viviparus, Adult
X
D. viviparus, L4
X
X
VALBAZEN®: Broad-spectrum eted control of internal parasites.
Efficacy comparison of
DECTOMAX Injectable vs. Ivomec vs. Cydectin
Parasite/Stage
VALBAZEN® (albendazole) is a broad-spectrum
oral cattle dewormer suspension that controls
four major groups of parasitic worms plus liver
flukes.
Control liver flukes as part of a strategic
deworming program.
Ostertagia ostertagi, Adult
O. ostertagi, L4
O. ostertagi, Inhibited L4
O. lyrata, Adult, L4
Haemonchus placei, Adult, L4
Trichostrongylus axei, Adult, L4
T. colubriformis, Adult, L4
T. longispicularis, Adult
Cooperia oncophora, Adult, L4
C. punctata, Adult, L4
C. pectinata, Adult
C. surnabada, Adult, L4
Bunostomum phlebotomum, Adult
Strongyloides papillosus, Adult
Oesophagostomum radiatum, Adult, L4
Trichuris spp., Adult
Dictyocaulus viviparus, Adult, L4
Thelazia spp., Adult
Hypoderma bovis
H. lineatum
Haematopinus eurysternus
Linognathus vituli
Solenopotes capillatus
Psoroptes bovis
Sarcoptes scabei
DECTOMAX
Injectable
X
X
X
X
X
X
X
X
X
X
X
X
Ivomec
Injectable
X
X
X
X
X
X
X
Cydectin
Injectable
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
X
With one product, you can control four major
groups of parasitic worms — tapeworms,
intestinal worms, stomach worms and
lungworms — plus liver flukes. VALBAZEN kills
inhibited fourth-stage Ostertagia (brown stomach
worm) larvae. And a special drench gun makes it
fast and easy to administer.
Internal parasites controlled in cattle:
• Mature liver flukes
• Tapeworms
• Stomach worms
• Intestinal worms
• Lungworms
Total drug availability comparison of
DECTOMAX Injectable vs. Ivomec and Cydectin
Lanusse C, Lifschitz A, Virkel G, Alvarez L, Sanchez S, Sutra JF, Galtier P, Alvinerie M.
Comparative plasma disposition kinetics of ivermectin, moxidectin and doramectin in cattle.
J Vet Pharmacol Therap 1997;20:91-99.
DECTOMAX Injectable provides more total drug availability at the target
tissues than either Ivomec or Cydectin.4
DECTOMAX® Pour-On: Weatherproof protection for external parasites.
Parasite control that beats ivermectin
by up to 21 pounds
Average weight differences
Ivermectin Pour-On
(Durvet)
DECTOMAX Pour-On
700
720
740
752
21 lb.
difference
760
Pounds
773
780
800
Data on file, Study Report No. 2339D-02-003D, Pfizer Inc.
Convenient parasite control that won’t
wash off.
DECTOMAX Pour-On lasts up to twice as long as
Ivomec® (ivermectin) Pour-On and generic ivermectin
pour-on brands.5 It controls more parasites, including
immatures, than Ivomec.6 Even when parasites are
ingested after treatment, DECTOMAX Pour-On kills
them in their tracks. And it drastically reduces fecal
egg counts for nematodes.7
Internal parasites controlled in cattle:
Compared with ivermectin pour-on, cattle treated with DECTOMAX
Pour-On demonstrated greater live weight at slaughter.8
DECTOMAX Pour-On delivers lower fecal egg
counts than ivermectin
40
Fecal Egg Counts (eggs/gram)
DECTOMAX® Pour-On delivers consistent efficacy
against worms, with a weatherproof formula that
keeps external parasites at bay.
24
16
8
0
Day -6 or -3
(P = 0.002)
Day 14
(P = 0.001)
Day 30
(P = 0.015)
Cattle treated with DECTOMAX Pour-On had significantly lower egg
counts on Days 14 and 30.8
Plasma-level comparison of
DECTOMAX Pour-On vs. Ivomec Pour-On
• Horn flies
• Mange mites
Label comparisons:
Length of protection from reinfection
DECTOMAX
Pour-On
Ivomec
Pour-On
Cydectin
Pour-On
Ostertagia ostertagi
(brown stomach worm)
28 days
14 days
28 days
Cooperia oncophora
(small intestinal worm)
28 days
14 days
0 days
C. punctata
(small intestinal worm)
35 days
21 days
0 days
Drug Concentration (ng/mL)
External parasites controlled in cattle:
Parasite
Generic ivermectin
Data on file, Study Report No. 2339D-02-003D, Pfizer Inc.
• Gastrointestinal roundworms
• Lungworms
• Eyeworms
• Biting lice
• Sucking lice
• Grubs
DECTOMAX Pour-On
32
DECTOMAX Pour-On provides a 45 percent greater total drug
availability5 than Ivomec over a 40-day period following application.9