Improving the health of Queenslanders
by delivering genomic medicine
1
QGHA Round 1 Project Fund:
Information Session
Webinar – Series 2
[email protected]
Executive Director
Improving the health of Queenslanders by
delivering genomic medicine
2
Call for Applications – Information
ApplicationsOpen:
12October2016
Face-to-FaceInformationSession:
7November2016
Webinar-basedInformationSession throughoutCall
ApplicationsClose:
16December2016
ApplicationDecisionMaking:
February2017
RegistrationandApplicationInformationis
availableatwww.qgha.org/project-round1
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Information Sessions
• Webinar Series 1: QGHA Status and Process
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Wednesday 19 October – 6:00pm
Monday 24 October – 3:00pm
Wednesday 26 October – 7:30am
Friday 4 November – 3:00pm
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• Face to Face Information Sessions
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• Webinar Series 2: Program Logic and Arrangements
• Date: Tuesday 7 November – 9:30am to 11:30am
• Location: Brisbane Entertainment & Convention Centre
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Tuesday 8 November – 7:30am
Monday 14 November – 10:00am
Thursday 17 November – 6:00pm
Tuesday 22 November – 7:30am
Thursday 24 November – 6:00pm
Thursday 1 December – 3:00pm
Queensland Genomics Health Alliance
w w w . q g h a . o r g
WEBINAR SERIES 2:
Information Session Agenda
1.An overview of the face to face Information Session
2.QGHA Round 1 Obligations and Milestones
3.Program Logic Overview and Application
4.Awarding Arrangements and Timing
Queensland Genomics Health Alliance
w w w . q g h a . o r g
• Recognising Queensland’s capabilities in clinical genomics research
• Queensland Health investment - $25M, 5 Year Program
• Clinically-led and patient-centred translational research and
implementation focus
• Capability building through evidence-based research and researchclinician collaboration
“to demonstrate the value of genomic medicine in
everyday Queensland healthcare”.
Proudlysupportedby:
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Objectives and Goals
1.Workforce able to incorporate genomics into healthcare
2.Evidence base for clinical genomics
3.Timely and cost-effective diagnostic workflows
4.Genomic sequencing results are used for the benefits of
patients
5.Public awareness and understanding
6.System for the management of clinical genomic data
7.Accelerated translation of research
8.Positive contribution nationally and internationally
Queensland Genomics Health Alliance
w w w . q g h a . o r g
A strategic perspective of the QGHA
funding program
$5.8m
$5.8m
$4.8m
Round 3
Round 2
Institute legacy
Round 1
Start-Up &
Business
Readiness
Workshops
Statewide
Implementation
“Business as Usual”
Considered further investment
Discovery, Learn &
identify future investment
Queensland Genomics Health Alliance
w w w . q g h a . o r g
QGHA Projects
Queensland Genomics Health Alliance
w w w . q g h a . o r g
WEBINAR SERIES 2:
Information Session Agenda
1.An overview of the face to face Information Session
2.QGHA Round 1 Obligations and Milestones
3.Program Logic Overview and Application
4.Awarding Arrangements and Timing
Queensland Genomics Health Alliance
w w w . q g h a . o r g
QGHA: Obligations, Deliverables and
Milestones
Context – The QGHA high level Timeline:
Not to scale
QGHAWorkshops
Jul16
Round1
Business
Readiness
Round1:
CallFor
Projects
Jun17
Round1:
Review&
Awarding
Jan18
Dec18
4xClinicalDemonstrations
5xCapability-buildingWorkstreams
Round2:
Prep
Round2:Programme
QGHARound1Contract
October2016
Funding
Funding
Feb17
Jan 20
Jun21
Round1:Programme
Round1Preparation
QGHA
Establishment
Contract
Jan-Jun2016
Funding
Dec16
Round3:
Prep
Funding
Aug17
Funding
Feb18
Funding
Aug18
Queensland Genomics Health Alliance
w w w . q g h a . o r g
IndicativeTimingfor
Subsequent
ProjectRounds
Round3:Programme
QGHA Milestones (Schedule 2)
KeyMilestones
DatesandTiming
Delivery Plan&ProgramLogic
FinalbyJanuary2017
CallforApplications
October 2016
Applications CloseforRound1
16December
Independent PanelRecommendations
4weeksafterclose(noteXmas/new-year)
SuccessfulApplicantsadvised
WithinonemonthofQHDecision
ContractsExecuted
Withintwomonthofnotification
Round1ProjectsCommence
Withinonemonth ofcontractexecution
Program ProgressReport
Withinnine monthsofprojectcommencement
Program ReviewReport/Meetings
Quarterly
ProgramFinancialReporting
Within60daysofthe endoffinancialperiods
ConductGovernanceReview
Withinninemonthsofproject commencement
GovernanceReviewReport
Withintwelvemonthsofproject commencement
Queensland Genomics Health Alliance
w w w . q g h a . o r g
QGHA: Obligations
• Delivery Plan including the Program Logic
• Program Governance Meeting Reports
• Progress and Activity Reports
• Financial Expenditure/Commitment Reports
• Governance Review Report
Queensland Genomics Health Alliance
w w w . q g h a . o r g
QGHA: Making the time work
Jan 17
February
Decision
Award
March
April
Contract
May
Initiation
1. Clinical Projects Detailed Planning
2. Capability Workstream Program
3. Round 1 Program Planning
4. Round 1 Operational Governance
5. Program Startup
Queensland Genomics Health Alliance
w w w . q g h a . o r g
June
QGHA: Data Management
To ensure progress and outcomes resulting from this
proposal are well communicated to the clinical
genomics research community and to foster
potential collaborations, please outline plans for
1. communicating the research results to other
researchers and the broader community,
including scholarly and public communication
and dissemination;
2. the management of data produced as a result of
the proposed project, including but not limited to
storage, access and re-use arrangements.
Queensland Genomics Health Alliance
w w w . q g h a . o r g
QGHA: Data Management
Effective research data management is a cornerstone of the
responsible conduct of research.
Sounddatamanagementprocedurescan:
• Increasetheefficiencyofresearch
• Helpguaranteethequalityandauthenticity
ofdata
• Enabletheexposureofresearchoutcomes
throughcollaborationanddissemination
• Provideforthereproducibilityof
experimentalandcomputationaloutcomes
• Facilitatethevalidationandverificationof
results
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Shared Resources
• Support ‘common project needs’ across
projects and the overall Alliance.
• Shared resources may include, but not be
limited to: project communication and
marketing, Data Entry staff, Bio-informaticians
and a Coordinator of Genetic Counsellors.
• The final allocation of Shared Resource Pool
Fund will be established through requirements
assessment against the successful project
applications.
Queensland Genomics Health Alliance
w w w . q g h a . o r g
WEBINAR SERIES 2:
Information Session Agenda
1.An overview of the face to face Information Session
2.QGHA Round 1 Obligations and Milestones
3.Program Logic Overview and Application
4.Awarding Arrangements and Timing
Queensland Genomics Health Alliance
w w w . q g h a . o r g
QGHA Program Logic in Operation
The Program Logic will address the following Critical
Success Factors for QGHA:
• A Collaborative and Integrated program approach
• Embedded Change Strategies and Enablers
• Clear Governance, Ownership & Accountability
• Interdisciplinary, cross-organisational collaboration
• A Phased Approach
• Practical standards, methods and processes
• Continued Financial Support
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Program Logic – Adaptive Management
• Adaptive Management strategies are at the heart
of the Program Logic
• A proportion of resources are therefore dedicated
to planning, monitoring and evaluation
• Stakeholders are critical to planning and
evaluation
• Centralised monitoring and evaluation
• Learning come from the projects into the centre
• Application of smart or double learning loops
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Program Logic - Evaluation
The Program Logic will employ an ongoing and
dynamic evaluation framework to assess the extent
to which the outcomes have been achieved.
The Program logic directs the evaluation and frames
the questions and enables adaptive management
and learnings across the program.
The Program Logic determines the type of evaluation
to be conducted:
1. Needs Assessment
2. Process Evaluation
3. Outcome Evaluation
4. Impact Evaluation
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Project Requirements
• Section C: Project Plan, Budget, and Logic (Weighting: 25%)
This section focus on the proposed project plan, hypothesis,
clear deliverables and milestones; a realistic and defensible
budget within the limits set by QGHA; and includes a sound
project logic supporting an effective roll-up to program level
to identify and manage risks, inter-project dependencies and
collaboration opportunities.
The key outputs and deliverables should provide a solid
foundation and detailed scoping of future QGHA projects in
the context of the QGHA’s long-term goals and objectives.
• C.1 Project Plan, hypothesis, milestones, and proposed
project timelines and deliverables. (Maximum 750 words)
• C.2 Project methodology and logic diagram (approach,
design, and techniques proposed). (Maximum 500 words)
Queensland Genomics Health Alliance
w w w . q g h a . o r g
QGHA Program Logic
Inputs
Commissioning
Agent
Administering
Agent
Alliance
Members
Genomic
Initiatives
Project
Teams
QGHA
MajorRole
Funding&
Approval
Contracting&
Operational
Oversight
Inputexpertise.
Collaborate asa
community.
Inputexpertise.
Informed
strategic
investment.
Deliver
Projects
Programme
Management&
Stakeholder
Engagement
Outcome
Themes
1. Acceleratingintegrationofclinical
genomicsinhealthcare.
2.Growingclinical
genomicscapability.
3.Buildingclinicalgenomics
serviceinfrastructure.
1.1Anevidencebaseforclinical
genomicsinpractice.
1.2.Acceleratedtranslationofclinical
genomicresearchintohealthcare.
Outcomes
1.3 Genomicsequenceresultsare
usedforbenefitofpatients.
3.1Asinglesetof
standards,policiesand
proceduresexistwhich
supportacommon
infrastructureofthe
managementanduseof
genomicdata.
2.1Emergingand
existingQueensland
healthworkforceis
abletoconfidently
andaccuratelyuse
genomicinformation
inclinicaldecision
making.
Patients
Benefits
Improved
Patient
Outcomes
Clinical&Diagnostic
Workforce
HealthService
Infrastructure
Researchers
GenomicData
Knowledge&PracticeGenomics
Standardised
Queensland
Health Availability
Alliance
Increasedpatientflow
Practice
4.1Demonstrate
thevalueof
genomic
medicinein
everyday
healthcare.
3.2Timelyandeffective
diagnosticworkflows
providedinanevidencebasedmanner.
1.4 Publicawarenessand
understandingofclinicalgenomics.
Outcome
Recipients
4.Contribute,
nationallyand
internationally.
CommunityLink
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PolicyMakers
Health
System
Economic
Assessment
Clinical
Implementati
on
WEBINAR SERIES 2:
Information Session Agenda
1.An overview of the face to face Information Session
2.QGHA Round 1 Obligations and Milestones
3.Program Logic Overview and Application
4.Awarding Arrangements and Timing
Queensland Genomics Health Alliance
w w w . q g h a . o r g
QGHA Projects – Legal Structure
• The QGHA initiative is funded by Queensland Heath
• The University of Queensland (UQ) has been appointed
by Queensland Health to lead the initiative
• To enable UQ to facilitate the program, UQ has signed a
Funding Agreement with Queensland Health
• UQ is required to conduct the program and expend the
funding in accordance with the terms of the Funding
Agreement
• The Funding Agreement sets out how UQ is to engage
those parties who have been chosen to conduct the
projects
• Queensland Health, as a condition of the funding
provided to UQ, requires that Research Services
Agreement contains certain terms and conditions
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Research Service Agreements
• Successful project applicants will be required to enter
into a Research Services Agreement with UQ.
• Certain terms and conditions contained in Research
Services Agreement are a requirement of the Funding
Agreement between UQ and Queensland Health.
• These prescribed terms include matters such as:
•
•
•
•
•
milestones and delivery
intellectual property
reporting on progress and financials
privacy and personal information
Indemnity and termination
• UQ will enter into the Research Services agreement
with the successful project lead only
• It will be the responsibility of the project lead to enter
into agreements with other collaborators,
subcontractors and service providers (as relevant).
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Concluding Statements:
Please visit the Round One Project Fund website:
www.qgha.org/project-round1
All correspondence and enquiries should be
forwarded to [email protected]
Telephone conversations will not be conducted to
ensure consistency of information provided.
Queensland Genomics Health Alliance
w w w . q g h a . o r g
Thankyouforattendingtoday’sinformation
sessions.Moreinformationisavailableat
theQGHAProjectWebsite.
Improving the health of Queenslanders
by delivering genomic medicine
28