Industrial & Consumer Specialties
Personal Care
A unique solution for complete skin repair
VitipureTM
Formulating with
VITIPURETM
VITIPURE™ can be formulated into O/W
and W/O emulsions as well as aqueous
gels. It is most conveniently incorporated
after preservatives have been added to
the formulation. Various aesthetic
properties can be achieved with
VITIPURETM depending on addition order:
•
•
•
Water phase – aqueous & light touch
Oil phase – caring feel
At the end – rich and substantive feel
The addition of VITIPURE™ could lead to
moderately higher viscosities. It is best to
incorporate the product below 50˚C,
although temperatures of 80˚C are
tolerated for a brief period. VITIPURE™ is
stable over a wide pH range.
Recommended
Use Levels
• VITIPURE™ can be used in the range of 0.5 – 2.0%.
• Studies conducted on the anti-aging and skin repair benefits of
VITIPURE™ included 1.5% VITIPURETM Feeling in test formulations.
• VITIPURE™ can be used in the range of 0.5 – 1.0% for a sensory effect.
Compatibility
• There are no known incompatibilities for VITIPURE™ in cosmetic
products.
• For Deco-Cosmetics the use of VITIPURE™ Sensation is recommended
due to its smaller particle size.
Solubility
• VITIPURE™ is easily dispersible in water, oil and hydroalcoholic
solutions.
VITIPURETM
VITIPURETM is a novel biotech innovation that benefits consumers of
all age groups by providing the advantages derived from natural
products without sacrificing product performance or aesthetics.
VITIPURETM has been shown to enhance skin elasticity and firmness,
while making it feel luxuriously smooth to the touch. The unique
complex provides superior benefits for skin repair and anti-aging.
The unique, patented biopolymer, VITIPURETM, consists of a covalently
linked chitin-glucan polysaccharide complex. It is of vegetal origin,
derived from bio-fermentation of Aspergillus Niger. This novel
approach to vegetal chitin provides a unique solution for healthy,
youthful skin.
Beta (1,3)-glucan
Key Functions
•
•
•
•
•
Skin barrier function restoration
Immune-stimulating properties
Improvement in skin elasticity and firmness
Skin surface micro relief organization
Skin hydration
Chitin
Which VITIPURETM fits your formulation needs?
VITIPURETM Feeling
• Larger particle size: ≥ 95 % are ≤125 µm
• Ideal for use in skin, hair and sun care formulations
VITIPURETM Sensation
• Finer particle size: ≥ 95 % are ≤30 µm
• Ideal for use in color cosmetics and lip care formulations
VITIPURE™ at a Glance
Specification
INCI: Chitin, Beta-Glucan
Fine, off-white powder
Odorless
>90% Dry matter
Source & Process
Renewable, Inexhaustible, Traceable
Consistent quality
Non-GMO
ISO & HAACP compliant
Toxicity
Non-irritating
Hypoallergenic
Non-phototoxic
Non-ecotoxic
Regulatory
Considered a polymer under the EU REACH legislation
Anti-Aging Benefits
Multi-dimensional wrinkle reduction
Panelists using cream with 1.5% VITIPURETM Feeling had a significant reduction in the number and depth of skin
microreliefs, as determined using image analysis. The total wrinkled surface area was reduced by 24% after only 8
weeks. 90% of panelists observed a positive effect in the 16 week study.
Cream Efficacy
According to a subjective questionnaire,
the panelists perceived
•
•
•
•
Softer skin: 90%
More lifted skin: 77%
Smoother complexion: 75%
More hydrated skin: 71%
Panelists
N=20, Age 57-60, Women
Formulation
Moisturizing cream containing
1.5% VITIPURE™ Feeling vs.
control
Administration
Twice daily to the crow’s feet
region for 16 weeks
Instrumentation
Image analysis of skin replica
Reduced appearance of fine lines and wrinkles
Significant smoothing of skin microrelief was achieved in just 4 weeks with a cream containing 1.5% VITIPURETM
Feeling, in comparison to the control cream. Consistent improvement occurred throughout the 16 week study.
Panelists
N=20, Age 54-62, Men
Formulation
Moisturizing cream
containing 1.5%
VITIPURE™ Feeling vs.
control
Administration
Twice daily to forearm
for 16 weeks
Instrumentation
Optical profilometry of
skin surface replicas
0
4
Time (weeks)
Optical Profilometry
Fine lines, wrinkles, and deep microreliefs
due to aging, were quantified using optical
profilometry. A lower Rz value indicates
smoother skin. Smoother skin provides a
more healthy, radiant appearance.
8
12
16
0
2
4
6
8
Mean Depth Measurement , Rz (µm)
Cream with VITIPURETM Feeling 1.5%
10
Control
Statistical Significance: * p < 0.05, ** p < 0.01 vs. control
12
Skin Repair Benefits
Improved skin hydration with prolonged use
Skin hydration significantly increased for panelists using a cream with 1.5% VITIPURE™ Feeling throughout the 16 week
study. Short-term and long-term hydration benefits were observed in comparison to the control cream.
VITIPURE™ is an excellent water-binding
biopolymer, capable of retaining 10 times its
own weight in water. It forms an efficient, nonocclusive barrier that limits water loss through
evaporation. A higher electrical capacitance
value indicates greater water retention
capacity of the stratum corneum.
Time (weeks)
0
4
8
12
Panelists
N=20, Age 54-62, Men
Formulation
Moisturizing cream
containing 1.5%
VITIPURE™ Feeling vs.
control
Administration
Twice daily to forearm for
16 weeks
Instrumentation
Corneometer
Measurement 10h post-application
16
50
55
60
65
Smooth
skin
70
Electrical Capacitance Measurement, arbitrary units
Cream with VITIPURETM Feeling 1.5%
Control
Statistical Significance: * p < 0.05, ** p < 0.01 vs. control
Enhanced overall health of compromised skin
VITIPURETM Feeling reduced the physical parameters associated with Atopic Dermatitis and the need for steroid
cream in just 1 week. Initial benefits observed were maintained over 4 weeks.
Panelists
N=13, Exhibiting
atopic dermatitis;
4 adults, 9
children (6
children < 3yrs)
Formulation
Moisturizing
cream containing
1.5% VITIPURE™
Feeling
Following 2-day
steroid cream
initiation
period, twice
Administration
daily to 10 precise
regions (front and
back) for 4 weeks
Evaluation
Dermatologist
evaluation:
Average score = sum of
SCORAD scores for all 10
regions, average of all 13
panelists
Panelist evaluation:
Average number of sites =
number of sites panelists
needed to apply steroid
cream; average score
Clinical Signs of Atopic Dermatitis
Dermatologist evaluation
-62%
0
10
Average
SCORAD
Score
20
30
40
50
60
70
80
90
100
Improved Skin Health
Need for Steroid Cream
Panelist evaluation
-50%
0
10
Average
Number of
Sites
20
30
40
50
60
70
Improved Skin Health
80
90
100
www.personalcare.clariant.com
Clariant Corporation
Industrial & Consumer Specialties
625 E. Catawba Avenue
Mount Holly, NC 28120
Phone: 800 942 7239
Fax: 704 822 2241
E-mail: [email protected]
This information corresponds to the present state of our knowledge and is intended as
a general description of our products and their possible applications. Clariant makes
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sufficiency or freedom from defect and assumes no liability in connection with any
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property rights must be observed. Due to possible changes in our products and
applicable national and international regulations and laws, the status of our products
could change. Material Safety Data Sheets providing safety precautions, that should
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applies in addition: NO EXPRESS OR IMPLIED WARRANTY IS MADE OF THE
MERCHANTABILITY, SUITABILITY, FITNESS FOR A PARTICULAR PURPOSE OR
OTHERWISE OF ANY PRODUCT OR SERVICE. 9/2010
Copyright© Clariant Corporation, 2012