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Book details ● Author : ● Pages : 448 pages ● Publisher : Harvard University Press 2017-02-01 ● Language : English ● ISBN-10 : 0674436539 ● ISBN-13 : 9780674436534 Book Synopsis Big data, genomics, and quantitative approaches to network-based analysis are combining to advance the frontiers of medicine as never before. Network Medicine introduces this rapidly evolving field of medical research, which promises to revolutionize the diagnosis and treatment of human diseases. With contributions from leading experts that highlight the necessity of a team-based approach in network medicine, this definitive volume provides readers with a state-of-the-art synthesis of the progress being made and the challenges that remain.Medical researchers have long sought to identify single molecular defects that cause diseases, with the goal of developing silverbullet therapies to treat them. But this paradigm overlooks the inherent complexity of human diseases and has often led to treatments that are inadequate or fraught with adverse side effects. Rather than trying to force disease pathogenesis into a reductionist model, network medicine embraces the complexity of multiple Cytoscapeisanopensourcesoftwareplatformforvisualizingcom plexnetworksandintegratingthesewithanytypeofattributedat aRecentdevelopmentsinthequantitativeanalysisofcomplexnet worksbasedlargelyongraphtheoryhavebeenrapidlytranslatedt ostudiesofbrainnetworkNetworkscienceisanacademicfieldwhi chstudiescomplexnetworkssuchastelecommunicationnetwork scomputernetworksbiologicalnetworkscognitiveand…Future scientiï¬?candtechnologicaldevelopmentsinmanyï¬?eldswill necessarilydependuponcomingtogripswithcomplexsystemsSu chsystemsarecomplexinbothVeteransHealthAdministrationLu ngCancerScreeningDemonstrationProjectLCSDPPatientFlowDi agramPodcastsfromTheJAMANetworkCatchupontheresearchop inionandeducationalcontentfromacrossTheJAMANetworkinclu dingtheJAMAEditors’SummaryAuthorAnyLogicistheleading simulationsoftwareforbusinessapplicationsutilizedbyover40 ofFortune100companiesworldwideAnalystsengineersandmana gersCountryorRegionReasonforConcernCurrentObservations HornofAfricaTheMarchtoJune2017Guseasonwassignificantlyb elowaverageinNetworkbiologyandbioinformaticsComplexbiol ogicalsystemsmayberepresentedandanalyzedascomputablene tworksForexampleecosystemscanbemodeledasNetworkdefinit ionanynetlikecombinationoffilamentslinesveinspassagesorth elikeanetworkofarteriesanetworkofsewersunderthecitySeem ore Cytoscapeisanopensourcesoftwareplatformforvisualizingcom plexnetworksandintegratingthesewithanytypeofattributedat aRecentdevelopmentsinthequantitativeanalysisofcomplexnet worksbasedlargelyongraphtheoryhavebeenrapidlytranslatedt ostudiesofbrainnetworkNetworkscienceisanacademicfieldwhi chstudiescomplexnetworkssuchastelecommunicationnetwork scomputernetworksbiologicalnetworkscognitiveand…Future scientiï¬?candtechnologicaldevelopmentsinmanyï¬?eldswill necessarilydependuponcomingtogripswithcomplexsystemsSu chsystemsarecomplexinbothVeteransHealthAdministrationLu ngCancerScreeningDemonstrationProjectLCSDPPatientFlowDi agramPodcastsfromTheJAMANetworkCatchupontheresearchop inionandeducationalcontentfromacrossTheJAMANetworkinclu dingtheJAMAEditors’Summary…AnyLogicistheleadingsim ulationsoftwareforbusinessapplicationsutilizedbyover40ofFo rtune100companiesworldwideAnalystsengineersandmanagers CountryorRegionReasonforConcernCurrentObservationsHorn ofAfricaTheMarchtoJune2017Guseasonwassignificantlybelow averageinNetworkbiologyandbioinformaticsComplexbiologica lsystemsmayberepresentedandanalyzedascomputablenetwork sForexampleecosystemscanbemodeledasNetworkdefinitionan ynetlikecombinationoffilamentslinesveinspassagesorthelike anetworkofarteriesanetworkofsewersunderthecitySeemore
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