Papers Results What is already known on this topic We identified 292 eligible trials including a total of 258 315 participants that evaluated 75 different strategies for increasing response to postal questionnaires (for references see bmj.com). The trials identified were not restricted to medical surveys: one third were medical, epidemiological, or health related; one quarter were psychological, educational, or sociological; and two fifths were marketing, business, or statistical. All tests for selection bias were significant (P < 0.05) in five strategies: monetary incentives, varying length of questionnaire, follow up contact with non-respondents, saying that the sponsor will benefit if participants return questionnaires, and saying that society will benefit if participants return questionnaires. Tests were not possible in 15 strategies where fewer than three trials were included. The method of randomisation was not known in most of the eligible trials. Where information was available, the quality of the concealment of participants’ allocation was poor in 30 trials and good in 12 trials. The figure shows the pooled odds ratios and 95% confidence intervals for the 40 different strategies in which the combined trials included more than 1000 participants. We found significant heterogeneity among trial results in 17 out of the 31 strategies that included more than one trial. For trials of monetary incentives the heterogeneity among the results was significant (P < 0.0001): the odds of response initially increased with an increasing amount of money. This effect, however, levelled off when the amount greatly increased. Heterogeneity was also found among the results of trials examining the effect of questionnaire length (P < 0.00001): with increasing length of the questionnaire the odds of response decreased Postal questionnaires are widely used in the collection of data in epidemiological studies and health research Non-response to postal questionnaires reduces the effective sample size and can introduce bias What this study adds This systematic review includes more randomised controlled trials than any previously published review or meta-analysis on questionnaire response The review has identified effective ways to increase response to postal questionnaires this systematic review. Some strategies will require additional materials or administrative time, whereas others can be implemented at little extra cost. We have presented odds ratios for methodological reasons,4 but the practical implications of the odds ratio for a strategy may be difficult to interpret without knowing the response at baseline without the strategy. If the size of the effect that would be expected if a specific strategy were used is an important consideration for researchers, the data used in this review may be accessed through the Cochrane Library, where they will be updated regularly.5 We thank Peter Sandercock, Iain Chalmers, and Catherine Peckham for their help and advice with the study. Contributors: see bmj.com Funding: The study was supported by a grant from the BUPA Foundation and a Nuffield Trust short term fellowship. Competing interests: None declared. Discussion Before these results are implemented, several methodological issues must be considered. Identification and inclusion of all relevant trials We estimate that our search strategy retrieved nearly all eligible trials (estimated sensitivity 95%; 84% to 99%) and that we missed very few relevant records during screening.3 We excluded some trials because we could not confirm that participants had been randomly allocated to intervention or control groups, and we have not examined whether the results of these trials differ systematically from the included trials. Tests for selection bias were significant in five strategies. Although these results may be due to true heterogeneity between trial results rather than bias in the selection of trials,2 we cannot rule out the possibility of selection bias having an effect on the results. Methodological quality of trials In our review, information on allocation concealment was unavailable for most of the included trials. If they had inadequate concealment, this may have biased the results, which is unlikely in this context because the researchers making the allocations would find it difficult to predict propensity to respond to a questionnaire. Conclusions Researchers can increase response to postal questionnaires by using the strategies shown to be effective in BMJ VOLUME 324 18 MAY 2002 bmj.com 1 2 3 4 5 Armstrong BK, White E, Saracci R. Principles of exposure measurement in epidemiology. Monographs in epidemiology and biostatistics. Vol 21. New York: Oxford University Press, 1995:294-321. Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple graphical test. BMJ 1997;315:629-34. Edwards P, Clarke M, DiGuiseppi C, Pratap S, Roberts I, Wentz R. Identification of randomised controlled trials in systematic reviews: accuracy and reliability of screening records. Stat Med (in press). Engels EA, Schmid CH, Terrin N, Olkin I, Lau J. Heterogeneity and statistical significance in meta-analysis: an empirical study of 125 meta-analyses. Stat Med 2000;19:1707-28 Edwards P, Roberts I, Clarke M, DiGuiseppi C, Pratap S, Wentz R, Kwan I. Methods to influence response to postal questionnaires. Cochrane Library. Issue 2. Oxford: Update Software, 2002. (Accepted 3 December 2001) Corrections and clarifications This Week in the BMJ We inadvertently gave the dates the wrong way round in the key to the figure that accompanied the summary of the paper by Chiara Pandolfini and Maurizio Bonati (9 March, pp 582-3). This gave the impression that the quality of health information on the internet had decreased, whereas in fact it had improved. Canada sees a bigger role for private companies in health care In the news article by David Spurgeon (2 February, p 259) we were wrong to say that hip replacements have been contracted to private clinics in Alberta. Although standards for facilities that seek to provide overnight postoperative care and major arthroplasties were approved recently by the College of Physicians and Surgeons of Alberta, no private surgical facility in Alberta has been approved (yet) to provide those services. 1185
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